OBJECTIVE:To provide reference for standardizing the names of TCM from Rumex. METHODS:According to lit-erature research,the most frequently used names (such as Jinbuhuan,Tudahuang,Yangti) of TCM in Rumex were combed,and suggestions for existing problems were put forward. RESULTS & CONCLUSIONS:The TCM names were used confusedly,main-ly showing that inconsistent names of TCM from the same plant in different areas,same name of TCM from different plants in the same area,same name of TCM from different plants in different areas. The key to solving the confused use of names of TCM in Rumex is standardization and unification of medicinal plant source and names. It can be developed and solved in order by resource investigation and identification,establishing quality standard and excavating medicinal value,in which,conducting the resource in-vestigation and specie identification,determining the medicinal names,stipulating the official names and establishing the quality standard are the important work in future.

As inhibitors of osteoclasts, Bisphosphonates are a group of drugs used in the treatment of oncology patients with bone metastases. However, some reports have described osteonecrosis of the jaws occurring after taking drugs containing bisphosphonates. The advances in clinical manifestation, imaging findings as well as the mechanisms of bisphosphonate-associated osteonecrosis of the jaws were reviewed in this article.

Objective To study the relationship between the activity of interleukin-4 and interferon-? with steroid effect in children with primary nephrotic syndrome before initiation of steroid therapy. Methods The activity of interleukin-4 and interferon-? in the supernatants of monocytes cell cultures activated with phytohemagglutinin was assessed with enzyme-linked immunosorbentassay in 31 children with primary nephrotic syndrome before iniatiation of steroid therapy. After steroid treatment for 8 weeks, data of steroid sensitivity and resistance were analyzed. Results Before initiation of steroid treament, in steroid sensitivity children with primary nephrotic syndrome an increased proliferative response of interleukin-4 was found (P0.05). Conclusion The activity of interleukin-4 is a useful tool for evaluating the likelihood of steroid sensitivity in children with primary nephrotic syndrome.

Senecio cannabifolius var integrilifolius (Compositae), locally known as "Fanhuncao" in China, is a folk herb used for the treatment of pneumonia, virus influenza and bronchitis. To investigate the chemical constituents of this herb, water extract of the aerial parts was subjected to various chromatography on normal/reversed phase silica gel and Sephadex LH-20 column. Eleven compounds were obtained and identified on the basis of their physicochemical properties and spectroscopic analysis as senecine (1), p-hydroxy-benzeneacetic acid (2), protocatechuic acid (3), 2,5-dihydroxy-benzeneacetic acid (4), 3,4-dihydroxy-benzeneacetic acid (5), vanillic acid (6), caffic acid (7), succinic acid (8), 2-furoic acid (9), 1,2,4,5-tetrahydro-jacaranone (10), and 4-(pyrrolidin-2-one)-phenylacetic acid (11). Compound 1 was structurally identified to be a new compound;the other compounds were isolated from this plant for the first time.

Objective To assess the MRI features of cerebrum in idiopathic hypoparathyroidism (IHP). Methods MR images of 27 IHP patients were analyzed retrospectively emphasized on the location, appearance and signal intensity of the lesions. Results MRI showed symmetric abnormal signals in basal ganglia in 27 patients, in thalami and dentate nucleus in 21 patients, and in corona radiata-centrum ovale in 9 patients. All the lesions were hyperintensity on T1WI. Local hypointensity in basal ganglia was found in 4 patients, while hyperintensity or slight hyperintensity on both T2WI and T2-FLAIR were found in 26 patients, and slight hyperintensity with hypointensity on both T2WI and T2-FLAIR in 1 patient. Conclusion MRI of IHP has some features. Symmetric high signals on both T1WI and T2WI in basal ganglia, thalami and dentate nucleus have important diagnostic value for IHP.

Cisplatin is effective in the treatment of various solid tumors. However, its clinical application is limited because of the severe side-effects such as nephrotoxicity, hepatotoxicity, ototoxicity and so on. Drug combination is advocated in clinics for synergism and detoxication. In order to provide some referencs for the research of drug combination and clinical treatment regimen, the research advances in the synergism and detoxication of drug combination of cisplatin with chemicals/ traditional Chinese medicines in recent years are reviewed in the paper.

0.05 ). And the fitness values(?m) of the crown of DA9-4 alloy were:the margin gap of the crown 71.3 ?8.34, the shoulder gap 53.4?4.83, the axial wall gap 41.85?8.08, the occlusal lift amount 55.2?9.21.Conclusion:DA9-4 alloy has good fitness and can meet the require of clinic.

BACKGROUND:Recent research has shown that the proper concentration of aspirin can increase the proliferation and osteogenic ability of MG-63 cells.OBJECTIVE:To explore the effects of different concentrations of aspirin on osteoblast proliferation on the implant-cell interface under fluid shear stress.METHODS:(1) MG-63 cells were cultured in low-glucose DMEM containing 10％ fetal bovine serum and different concentrations of aspirin (0,0.023,0.046,0.0625,0.125,0.25,0.5,1.0,2.0,4.0 mmol/L) for 1-7 days.Then cell proliferation was detected using MTS method.(2) MG-63 cells were cultured on three different surfaces:glass slide,PT titanium surface and SLA titanium surface.After 3 days of culture with aspirin at a concentration of 0 or 0.5 mmol/L,the cells were subjected to fluid shear stress.MTS test was applied to estimate the proliferation of MG-63 cells at 0,0.5,1,2,4 hours after stress application.RESULTS AND CONCLUSION:(1) After 1-3 days of culture,0.023,0.046,0.5 mmol/L aspirin promoted the proliferation of MG-63 cells,while after 1-7 days of culture,1,2,4 mmol/L aspirin inhibited the proliferation of MG-63 cells.(2) Under the fluid shear stress,aspirin showed significant effects on the cell proliferation as confirmed by one-way analysis of variance (F=8.349,P=0.004),and 0.5 mmol/L aspirin inhibited the cellular proliferation of MG-63 cells.However,surface modification and stress loading time showed no significant effects on the cell proliferation (F=2.826,P=0.064;F=0.893,P=0.406).(3) Under the fluid shear stress,surface modification showed no significant effect on the cell proliferation of MG-63 cells cultured with 0.5 mmol/L aspirin (F=1.803,P=-0.171).Under the fluid shear stress,0.5 mmol/L aspirin significantly inhibited the proliferation of MG-63 cells on the glass slide (P=-0.003),while PT and SLA titanium surfaces showed on inhibitory effect on the cell proliferation (P=0.891,P=0.051).The present results demonstrate that the cell proliferation of MG-63 is related with aspirin in a concentration-dependent manner.In addition,different titanium surfaces may decrease the sensitivity of MG-63 cell proliferation to aspirin.

AIM To study the relationship between the activity of glutamate transporters and Parkinson's disease (PD), examine whether a novel ATP sensitive potassium (K ATP) channel opener Iptakalim (Ipt) hydrochloride enhances glutamate uptake activity, and to investigate its mechanisms. METHODS Rats were stereotaxically injected with 6 hydroxydopamine (6 OHDA) in SNpc. The synaptosomes from normal and PD rats were isolated, and [ 3H] glutamate uptake in synaptosomes was measured by using liquid scintillation counting. RESULTS [ 3H] glutamate uptake by synaptosomes from striatum and cerebral cortex of PD rats decreased and the redution was recovered by administration with Ipt (10, 50, 100 ?mol?L -1 ). The protective effect of Ipt was blocked by co adiministration with glibenclamide (20 ?mol?L -1 ), an inhibitor of sulphonylurea receptors. CONCLUSION Our results demonstrate for the first time the protective role of K ATP channel in glutamate uptake of synaptosomes and conceptually support the view that Ipt may have potential and feasibility in therapy for PD.

Objective To evaluate the value of MRI in the diagnosis of complex congenital heart disease.Methods Twenty-one patients with complex congenital heart disease,who had undergone MRI examination were enrolled in this research.The MRI data of every patient was analyzed and abnormalities of anatomy was counted by two experienced cardiovascular radiologist.Surgical diagnosis (17 cases) or consistent diagnosis (4 cases) of ultrasonic,cardiac catheter and cardiac CT was regarded as reference standards.Accuracy and misdiagnosis rate were obtained.Results Twenty-one patients had 63 main abnormalities,61 malformations was found by MRI examination,the diagnostic accuracy was 96.8％,and the misdiagnosis rate was 4.8％ (1 atrial septal defect (ASD) and 1 major aorta pulmonary collateral arteries (MAPCAS) were missed,1 arterialduct stump was misdiagnosed as patent ductus arteriosus (PDA).Conclusion MRI has excellent diagnosticaccuracy on complex congenital heart disease,it is another good noninvasive cardiac examination method beside ultrasonic.