OBJECTIVE To investigate the significance of the Fas and TNF-? receptor mediated apoptosis and IL-8 associated with the pathogenesis of aged COPD.METHODS We measured the circulating soluble Fas,tumor(necrosis) factor alpha(TNF-?) and interleukin-8 level in peripheral blood of 40 patients with aged chronic(obstructive) pulmonary disease (COPD).In contrast with the aged COPD group,30 healthy old people were(observed) as a control.RESULTS The level of soluble Fas,TNF-? and IL-8 in peripheral blood of these patients was higher than control((P

This study is based on the requirements of the construction of applied undergraduate colleges and development of excellent doctor education training pilot project of the ministry of education. The situation of higher medical education and the requirement of health career development are analyzed. The medical talents training mode of three oriented which is taking the post competency of medical students as the frame is constructed. This paper expounds the background proposed by training mode from the internal drive, external drive and project boosting. With the national education policy as the basis, the theoretical basis of the international advanced education teaching idea, theory and standard is explained. The connotation of the training mode is revealed by the humanistic quality education, professional quality training and physical and psychological quality cultivating. The evaluation strategy of clinical medical per-sonnel training standards, index system, the implementation approach and evaluation methods which have certain feasibility and timeliness is established.

BACKGROUND:Cam-type femoroacetabular impingement can impose elevated mechanical loading in the hip, and may eventual y result in hip osteoarthritis, while mechanical mechanism on how this deformity leads to osteoarthritis is stil unclear.
OBJECTIVE:To analyze intra-articular mechanical environment of Cam-type femoroacetabular impingement in hip joint using three-dimensional finite element method, and to further understand the features of pathological mechanics.
METHODThree-dimensional geometry models of normal and Cam-type femoroacetabular impingement joints were constructed using Mimics and Hypermesh software with the CT data of normal hip joint. These hip models were imported into LS-DYNA analysis system, then dynamic loads and motions for standing up and sitting down were applied to al joint models. Intra-articular cartilage contact pressures and stresses were analyzed in normal hip joint and hip joint with Cam-type femoroacetabular impingement.
RESULTS AND CONCLUSION:Based on CT data, models of normal hip joint and hip joint with Cam-type femoroacetabular impingement including articular cartilage for three-dimensional finite element analysis were accurately constructed. Peak contact pressures were 4.43 and 4.59 MPa at the anterosuperior region of the acetabular rim during sitting down and standing up. The peaks of Cam-type femoroacetabular impingement hip joint were 14.96 and 14.86 MPa. Peak pressures and stress concentration were found at the anterosuperior area of acetabular rim. High contact pressure at the acetabular cartilage may be the mechanical mechanism of osteoarthritis induced by Cam-type femoroacetabular impingement.

5.5 the separation was not achieved.The compound of cyclodextrin and terbutaline increased with the increase of cyclodextrin when the volume rate of cyclodextrin was 0.4% 1.6%,making terbutaline easier for separation.Conclusion:The types of ? CD,the concentration and pH of buffer are the major factors influencing the separation of terbutaline and it can be completely separated.

Dens in dente is a rare malformation of teeth.This article reports one case of type Ⅲ dens in dente of maxillary bilateral incisors with acute periapical lesion.The case was treated successfully by apexification with Vitapex paste.

Objective To implement XML-based electronic medical records' searching and querying using new technology of XML storing and indexing.Methods The information in electronic records was expressed with CDA XML standard,and XML Query and XML IR were used for querying of electronic records.Results Based on XML querying and indexing models,a new electronic medical record XML querying and searching system was built.Conclusion Querying and searching over XML database has been paid more attention to,with wide use of data adapting to HL7 CDA XML standard in electronic medical records.

Moyamoya disease (MMD) is a chronic progressive cerebrovascular disease with its reason remaining unclear; the disease has different morbidities among different races, with East Asia countries including China having higher incidence. The pathogenesis of MMD is still unclear and the clinical characteristics lack specificity, making it difficult for early diagnosis. Researches have shown that revascularization surgery can slow down the ischemic process, but no sufficient evidence indicates that revascularization surgery can be used for hemorrhagic MMD. Imaging approachs, including morphological and functional imaging, are the main diagnosis, evaluation and follow-up method for cerebrovascular diseases. This review aimed to summarize the application and research on multiple imaging methods for MMD.

Objective To observe the biocompatibility of bacterial cellulose and Schwann cells during in vitro co-culture, so as to lay a foundation for preparing tissue-engineered nerve with bacterial cellulose. Methods The bacterial cellulose was co-cultured with the dorsal root ganglion. The morphology, proliferation, and migration of the Schwann cells were examined by scanning electron microscope and optical microscope at day 1, 2, and 5, and the protein expression of S-100 was detected by immunocytochemical method. Schwann cells were also cultivated in the leach liquor of bacterial cellulose, and then optical microscope and immunocytochemical were used to observe the morphology and S-100 protein expression after 24, 48 and 72 hours; MTT and flow cytometry were used to evaluate the biocompatibility of the bacterial cellulose and Schwann cells. Results Schwann cells could grow and migrate on the surface of bacterial cellulose's membrane. The Schwann cell growth, proliferation and S-100 expression were not significantly affected by the leach liquor of bacterial cellulose as compared with the control group. Conclusion Schwann cells can grow well on the surface of the bacterial cellulose membrane and in its leach liquor, suggesting good biocompatibility with bacterial cellulose in vitro.

Objective To analyze the risk factors of venous thromboembolism (VTE) in elderly patients with diffuse large B-celllymphoma (DLBCL). Methods A total of 142 elderly DLBCL patients who were treated in our hospital from Jun. 2003 to Oct. 2013 were included in the present study. The relationship of VTE with gender, body mass index (BMI), physical score (ECOG-PS), tumor stage, lactate dehydrogenase level, hypertension, diabetes, hemoglobin level, white blood cell count, and platelet count were analyzed. The efficacy of current treatment of thrombosis was also analyzed. Results Univariate analysis showed that PS scor02 (P= 0. 027), IPI points= 3-4 (P= 0. 051), and non-CRafter 3-4 cycles of chemotherapy (P=O. 016) were risk factors for thrombosis in elderly DLBCL patients; multivariate analysis displayed that PS score2 and non-CRafter 3-4 cycles of chemotherapy were independent risk factors for thrombosis CP

Objective To compare the anti-infective effects of levofloxacin lactate and ceftizoxime in treatment of acute edema biliary pancreatitis, so as to provide reference for clinical anti-infective therapy of acute pancreatitis. Methods A total of 180 consecutive patients with acute edema biliary pancreatitis, who were treated in the emergency department of Changhai Hospital from January 2014 to November 2014, were selected in the present study, and they were randomly divided into levofloxacin lactate treatment group and ceftizoxime treatment group. In addition to conventional treatment including water fasting, gastrointestinal decompression, acid suppression, enzyme suppression and nutrition support, etc., levofloxacin lactate therapy and ceftizoxime were given separately to control the infection in the two groups. Then the following parameters were observed: remission of vomiting, abdominal pain and bloating, open eating time, hospital stays, blood routine and biochemistry test, C reaction protein (CRP), serum amylase, and the absorption of inflammation of the pancreas in imaging. Results The levofloxacin lactate treatment group had a significantly higher effective rate than the ceftizoxime treatment group (P <0.05). Compared with the ceftizoxime treatment group, the remission of vomiting and abdominal pain and bloating was significantly faster in the levofloxacin lactate treatment group (P <0.01); the open eating time, hospital stays hemogram and blood amylase recovery were also significantly improved in the levofloxacin lactate treatment group (P <0.05); and the absorption of inflammation of the pancreas in CT imaging was significantly faster (P <0.05). Conclusion The study shows that levofloxacin lactate is more effective than ceftizoxime in the anti-infective therapy of acute edema biliary pancreatitis.