It is important to establish successfully animal models in the study of pathogenesis,diagnosis and treatment of heart failure.This article reviewe drecent animal models of heart failure.

Objective: Various quantitative assessments of coronary heart disease(CHD) risk factors was performed to evaluate severity and predicting its occurrence rate.Methods:282 cases,were selected to be scored by Framingham,PROCAM(The Prospective Cardiovascular Munster Study) and Chinese risk scores respectively.We compared the relationship between three risk scores and severity,extent of coronary artery through correlation analysis,and subsequently analyzed their predictive value.Results: Chinese risk score,PROCAM risk score,Framingham risk score were significantly correlated with extent and severity of coronary artery atherosclerosis(CAAS),with PROCAM risk score,the highest correlation of it and Framingham risk score,the smallest.Risk scores increased with coronary artery pathological change advancing.The areas under resident operation character(ROC) of Framingham risk score was the least,whereas that of PROCAM was the largest.Conclusion: Among the three risk scores described above used to evaluate the severity of CAAS and predict incidence of CHD,PROCAM risk scores was the superior.