1.Non-open operation approach for the treatment of bening prostatic hyperplasia (BPH) complicated with Big Bladder Stones.
Chinese Journal of Minimally Invasive Surgery 2001;0(03):-
Objective To evaluate the mini-invasion approach for the treatment of BPH complicated with big bladder stones. Methods The clinical data of 30 cases of BPH complicated with big bladder stones treated by ESWL,mechanical lithotripsy using the visual lithotriptoscope and TURP or TUVP were retrospectively reviewed. Results 29 cases of big bladder stones were cleared up completely,and all of them were operated on successfully by TURP of TUVP.The operation time was short with minimal invasion The results were satisfactory.No severe complications and bladder stones have recurred up to now. Conclusions ESWL combined with mechanical lithotropsy using the visual lithotroptoscopy and TURP or TUVP is an effective.and non-open operation approach with mini-invasion for the treatment of BPH with big bladder stones.It applys to old patients with cardiovascular and pulmonary conditions,which would elevate the risk of operation.Proficiency in the technique is a key to a successful operation.
2.Research on the Influences of the Implementing Essential Medicine System on Compensation Mechanism of Primary Medical Institutions:analysis on system dynamics
Lülin ZHOU ; Feng JIN ; Changchun ZHAN
Chinese Health Economics 2013;(10):21-23
Objective: To analyze the influences of implementing essential medicine system on primary medical institutions and give suggestions. Methods: Using system dynamics method to construct the compensation mechanism model for primary medical institutions. Compare the growth in revenue and expenditure of primary medical institutions before and after essential medicine system implementation. Results: After the implement of essential medicine system, the growth in total expenditure and total income of primary medical institutions is steadier; when the annual growth rate of government financial subsidies invested more than 13%, the growth in total receipts will keep balance. Conclusion: It’s better to guarantee the government financial subsidies invested in time, raise medical service price properly and establish comprehensive compensation mechanism for implementing compensation mechanism of primary medical institutions.
3.Effects of the Increasing-Energy and Renewing-Wisdom granule on charting-assessed vitality of vascular dementia patients
Jianying ZHOU ; Changchun SUN ; Yuexin GU
Journal of Medical Postgraduates 2003;0(05):-
Objective:To observe the effects of the Increasing-Energy and Renewing-Wisdom granule on vascular dementia(VD) patients. Methods:42 VD patients were divided randomly into 2 groups. The patients in treatment group administered the Iincreasing-Energy and Renewing-Wisdom granule. The patients in control group administered piracetam. All the patients were treated for 3 months. Results: The patients' scores of HDS, MMSE, Wechsler (order), MQ in the treatment group were higher than those before the study (P
4.Effect of Xiao Jianzhongtang on AMPK/PGC1-α Signal Pathway in Skeletal Muscle of Exercise Fatigue Mice
Zhi-hui LIN ; Qing-ying ZHOU ; Meng-ni WANG ; Bing LING ; Pai LIU ; Jun-peng GUO ; Hong-yan LIU
Chinese Journal of Experimental Traditional Medical Formulae 2020;26(13):73-78
Objective:To observe the effect of Xiao Jianzhongtang on Adenylate-activated protein kinase/peroxidase proliferation-activated receptor coactivator 1-
5.Research progress on Parkinson disease pain classification and treatment plans
Journal of Apoplexy and Nervous Diseases 2023;40(12):1149-1152
Parkinson disease is a common neurodegenerative disease characterized by motor and non-motor symptoms, and pain is one of the typical non-motor symptoms that has considerable negative impact on the daily life of patients with Parkinson disease, which has been a clinical focus. For the various types of pain in Parkinson disease, the treatment options are different, and early pain identification and early reasonable and effective treatment can delay the progression of the disease. This study presents the Parkinson disease pain classification and treatment plans, aiming to provide a basis for clinical diagnosis and treatment.
6.Nosocomial Lower Respiratory Infection and General Anesthesia: A Risk Factor Analysis and Prophylaxis
Guoming HAO ; Hongjun ZHU ; Xiangwei LIN ; Zhou ZHANG ; Changchun ZHANG
Chinese Journal of Nosocomiology 2006;0(05):-
OBJECTIVE To explore the factors and effective preventive method of nosocomial lower respiratory(infection) after general anesthesia through trachea intubation.METHODS Using bacterial culture and identification technique to detect the samples collected from pipe and the sides of anesthetic machine,from disposable virus/(bacteri)a respiratory filter and buccal and bronchial secretion of patients with general anesthesia through trachea(intubation.) RESULTS Eight of 15 anesthetic machines without disinfection were with positive bacterial culture.All sides of virus/bacteria respiratory filter,and buccal and bronchial secretion of patients during operation had same(bacteria.) No bacteria growth was found in anesthetic machine and disposable virus/bacteria respiratory filter used after operation.The same bacteria as from buccal secretion were isolated from anesthetic machine in patients(without) using virus/bacteris respiratory filter.CONCLUSIONS The(results) showed the anesthetic machine is more easy to be contaminated by patients,and the reuse of anesthetic machine is an important factor for nosocomial(lower) respiratory infection after general anesthesia through trachea intubation.Intensifying periodic disinfection of(anesthetic) machine and using virus/bacteria respiratory filter can prevent contamination between anesthetic(machine) and patients and decrease nosocomial lower respiratory(infection) after operation.
7.Mitochondrial DNA Polymorphism Associated with Longevity in Taklimakan Desert Uygur Centenarians
Nijiati MUYESAI ; Changchun QIU ; Zuheng CHENG ; Wenyu ZHOU
Journal of Medical Research 2006;0(06):-
Objective Sequence variations in mitochondrial DNA genes have been found to influence successful aging and longevity. The aim of this study was to examine whether mitochondrial DNA polymorphisms influenced the longevity in Chinese Uygur population.Methods We genotyped the mt5178A and mt10398G in 277 sampels representing three age group (centenarian, n=65; longevity, n=100; controls, n=112) from Taklimakan desert Uygur centenarians,China Results The distribution frequency of the 5178A in the centenarian (51/65, 78.5%) is slightly higher than in those of controls (63/112,56.3%,P=0.0029) . The frequency of the 10398G were significantly higher among the centenarian(47/65,72.3%)and longevity(68/100,68%) in comparison to the controls(60/112,53.6%,P
8.Effect of Intensive Insulin Therapy on Inflammatory Level of Biliary Pyemia
Changchun PU ; Xigui ZHOU ; Jieliang HU ; Faping LI
Chinese Journal of Bases and Clinics in General Surgery 2008;0(12):-
Objective To explore the possible anti-inflammatory mechanism of intensive insulin therapy (IIT) by studying the effect of IIT on the levels of TNF-?,IL-6,C-reactive protein (CRP) and APACHE Ⅱ score in biliary pyemia.Methods Twenty eight patients with biliary pyemia who were admitted by our department and given an operation within 24 h form Jan.2005 to Dec.2008 were randomly divided into two groups by using random number table numbers:one group treated with IIT (IIT group,n=14) and another group treated with routine insulin therapy (RIT group,n=14).The inflammatory factors,such as TNF-?,IL-6 and CRP were detected dynamically and the APACHEⅡ score was calculated.Results The level of CRP and APACHEⅡ score on day 5 and 7 and the levels of TNF-? and IL-6 on day 3,5 and 7 after operation in IIT group were significantly lower than those in RIT group (P
9.Effect of spinal anesthesia on serum troponin T in the elderly patients during the perioperation
Zhou ZHANG ; Changchun ZHANG ; Ping WU ; Xinfa CHEN ; Liangjie ZHENG
Chinese Journal of Primary Medicine and Pharmacy 2009;16(3):484-486
Objective To explore the security of spinal anesthesia by observing the pefioperation serum troponin T in the elderly patients with coronary heart disease who underwent spinal anesthesia.Methods 40 case8 were divided into two groups according to the elderly patients with or without the history of coronary heart disease.Group Ⅰ 0f 20 cases were the patients with the history of coronary heart disease.Group Ⅱ of 20 cases were the patients without the history of coronary heart disease.Both groups were undertaken single spinal anesthesia combined with epidural anesthesia.The blood samples were collected at the time of perioperation,the end of the operation and 24 hours after surgery.The serum troponin T Was tested by Roche fully automated ehemiluminescent analyzer E170.The symptoms and signs of the coronary heart disease in the patient were observed.And the age,operation time,anesthesia lever,the amount of bleeding and transfusion were recorded,and at the same time,electrocardiogram,heart rate,pulse,cerebral oxygen saturation were monitored.Results There was no significant difference between two groups in age,operation time,anesthesia lever,the amount of bleeding and transfusion,heart rate,pulse,cerebral oxygen saturation.There was no significant difference between two groups in seram troponin T.No symptoms and signs of the coronary heart disease were observed in two groups.There Was no significant difference between two groups in constituent ratio of positive rate of serum troponin T.There was one case in each group that serum lroponin T was more than reference value (0.010μg/L)during the perioperation while the patient was no discomfort.Conclusion Spinal anesthesia has no impact on the change of perioperative 8ertlm troponin T in the elderly patients with coronary heart disease.
10.Genetic analysis of ?-ADDUCIN and GNB3 in essential hypertension patient
Hongye ZHAO ; Jun CAO ; Li ZHOU ; Bin WANG ; Changchun QIU
Basic & Clinical Medicine 2006;0(04):-
Objective To explore the polymorphism at position G460W of ?-ADDUCIN and at position C825T of GNB3,and the genetic interaction between ?-ADDUCIN and GNB3 genes in a QiQihr essential hypetension population.Methods Three hundreds and thirty-one patients with EH and two hundreds and ninety-three healthy controls were enrolled.Genotyping was performed using PCR-RFLP technique.Results(1)genotype distributions of ?-ADDUCIN G460W(GG 0.177 vs 0.160,GW 0.580 vs 0.481,WW 0.242 vs 0.359,P=0.006) and GNB3(CC0.177 vs 0.353,CT 0.468 vs 0.541,TT 0.355 vs 0.106,P