4.Research progress of Mesenchymal stem cells and its function
Cheng CHANG ; Jingxiang SONG ; Lie WANG ; Xiaohuang TU
International Journal of Surgery 2011;38(5):331-334
Mesenehymal stem cells(MSCs)have been successfully isolated from almost all tissues in Mammals,and their multi-lineage differentiation ability leads to the attractive application of MSCs in regenerative medicine.More understanding of the biological characteristics of MSCs,the interaction between MSCs and the local environment,the molecules regulating MSC homing and differentiation have been achieved,which will benefit the effective clinical trials using MSCs as repair cells and/or vehicles for exogenous genes.
5.Application of nursing project in improving self-management ability of outpatients with chronic kidney disease
Xinyuan SONG ; Jie HAO ; Li XIAO ; Wenxiu CHANG ; Shen WANG
Chinese Journal of Nursing 2017;52(6):692-697
Objective To enhance patients' abilities in self-management. Methods We used the nursing project method to analyze reasons and develop standard process of follow-up management and health education. A retro-spective analysis of 84 patients with stage 3 to 4 CKD was performed by nursing project method. This analysis compared the changes after the intervention program,including the ability of self-management,follow-up,medication and diet compliance,and the control rate of physiological indicators. Results By comparison with the intervention before and after,there were significant improvements in each dimension of self-management ability (P<0.001),follow-up, medication and diet compliance were significantly improved(P<0.05),and there were significant improvements in the control rate of systolic pressure and blood uric acid(P<0.001),the differences were statistically significant. Conclusion The application of nursing project can improve self-management ability,the compliance of follow-up,medication and diet as well as physiological indicators in patients with stage 3 to 4 CKD.
6.Relationship between the expression of iNOS and tumor angiogenesis and prognosis of gastric carcinoma
Zhengjun SONG ; Fenrong WANG ; Hongxia LI ; Xinming CHANG
Journal of Xi'an Jiaotong University(Medical Sciences) 2003;0(06):-
Objective To investigate the expression of indu ci ble initric oxide synthase(iNOS) in gastric carcinoma and its relationship with angiogenesis and the prognosis. Methods Immunohistochemical staining method was used to det ect the expression of iNOS, VEGF CD34 in gastric carcinoma. Results The positive expression of iNOS in gastric carcinom a was 58.70% and iNOS was not detected in normal gastric tissue. The rate of the positive expression of iNOS in stage Ⅳ was higher than that in stageⅠ~Ⅲ. Th e positive expression of iNOS in gastric carcinoma with lymph node metastasis wa s higher than those with no metastasis. The MVD was 59.88? 18.02/HP and 55.5 9+ 19.39/HP in gastric carcinoma positive for iNOS and VEGF, repectively, obviou sly higher than those with negative expression of iNOS and VEGF, repectively ( P
7.Effect of Suitable Sport Walking on Heart and Lungs Functions in Old Women
Jian-guo ZHAO ; Ke-xin TANG ; Song WANG ; Huamei CHANG
Chinese Journal of Rehabilitation Theory and Practice 2006;12(8):729-730
ObjectiveTo observe the effect of sport walking on heart and lungs functions in old women.MethodsForty-two old women aged from 60 to 69 had sport walking for 4 months; the speed and intensity were controlled according to their heart rate respectively. The indexes of respiration, circulation and rheoencephalography were measured before and after exercise.ResultsAfter exercise, blood-pumping function of heart improved obviously, stroke volume increased from (65.22±11.41)ml to (72.10± 10.78)ml, ejection fraction increased from (60.10±5.03)% to (68.78±6.25)%, while heart rate declined from (77.45±8.69) times/min to (7.89±8.21)times/min, capacity increased from (2.86±0.36)L to (3.34±0.53)L, and maximal voluntary ventilation for every minute increased from (96.14± 15.21)L to (114.02±16.01)L, significantly different compared with that before treatment ( P<0.01). The fluid time of rheoencephalography reduced from (0.171±0.058)s to (0.128±0.049)s ( P<0.01).ConclusionSport walking under proper intensity can improve the function of respiration and circulation system in old women, so it is a good way to keep health for the elders.
8.Influences of Compound Kusanqi Capsules on expressions of Bcl-2, Bax, Fas and FasL of colonic mucosal cells in rat model of ulcerative colitis
Chang-Song WANG ; Song-Ping QIU ; Jian CHEN
Journal of Beijing University of Traditional Chinese Medicine 2010;33(2):110-112
Objective To observe the interventional effect of Compound Kusanqi Capsules on the apoptosis of colonic mucosal cells in rat model of ulcerative colitis (UC).Methods The rat model of UC was established by administrating dinitrochlorbenzene (DNCB), alcohol and acetic acid. The model then was intervened by Compound Kusanqi Capsules in high dose, middle dose and low dose respectively. The curative effect was observed through detecting the expressions of modulin Bcl-2, Bax, Fas and FasL of colonic mucosal cells in the model.Results After the intervention for 15 days the expressions of Bcl-2, Bax, Fas and FasL of colonic mucosal cells were improved in varying degrees in the groups of high-dose, mid-dose and low-dose Compound Kusanqi Capsules, which had significant difference statistically compared with those in the model positive control group (P<0.01 or P<0.05).Conclusion Compound Kusanqi Capsules has the regulation effect on the apoptosis of colonic mucosal cells in rat model of UC.
9.Determination of Lonicerae Flos in Compound Yuxingcao Tablets
Qiaoji GUO ; Chang SU ; Qian SONG ; Jing LUO ; Jue WANG ; Shuhong WANG ; Tiejie WANG
China Pharmacist 2015;(8):1416-1419
To study the quality of Lonicerae iaponicae flos in compound Yuxingcao tablets. Methods: HPLC-ELSD and LC-MS/MS were used to determine Lonicerae flos using macranthoidin A, macranthoside B and dipsacoside B as the control. Re-sults:HPLC-ELSD was suitable for the detection of Lonicerae flos in compound Yuxingcao tablets. LC-MS/MS was used to verify the results, which could identify the certified or counterfeit Lonicerae iaponicae flos in the samples. Conclusion:The two methods can be used to control the quality of Lonicerae iaponicae flos in compound Yuxingcao tablets.
10.Investigation on the morbidity and mortality of pneumosilicosis in a quartz factory.
Dan-Cheng YAO ; Guang-Song WANG ; Guang-Cheng ZHU ; Zhu-Ping CHANG ; Hong-Chun WANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2004;22(4):277-277
Adult
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Aluminum Silicates
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China
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epidemiology
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Female
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Humans
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Male
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Middle Aged
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Occupational Exposure
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adverse effects
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statistics & numerical data
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Quartz
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adverse effects
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analysis
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Silicosis
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epidemiology
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mortality