1.A New Algorithm for Displaying the Cutting Isosurface of Structures
Hou QING ; Zhiyong CHANG ; Yeying GUI ; Qing CAI ; Shong QING
Journal of Biomedical Engineering 2001;18(2):312-315
The existing algorithms for displaying the cutting isosurface of the structure are not suitable for interactive display because they spend too much time on calculation when a fair amount of data is submitted to processing. This paper presents a new algorithm for accelerating the cutting of structure by using the area partition and the increment calculation to reduce the unnecessary calculation in cutting the structure. It is suitable for real time interactive displaying, especially in the case of a vast amount of data.
2.Significance of fiberoptic bronchoscopic brush cytology in lung carcinoma diagnosis
Yong CHEN ; Yanhua CHANG ; Qing GUO ; Ying CAI ; Rongchao SUN
Clinical Medicine of China 2015;31(8):737-739
Objective To evaluate the significance of fiberoptic bronchoscopic brush cytology in the diagnosis and histological classification of lung carcinoma.Methods Data of 309 patients with lung carcinoma were retrospectively analyzed.Both bronchoscopic cytology and histology diagnosis were available.The positive rate of bronchoscopic cytology and tissue biopsy were calculated respectively.The classification accuracy of cytological diagnosis for lung carcinoma was evaluated.In tissue biopsy standard,evaluated the significance of bronchoscopic cytology in diagnosis and histological diagnosis.Results The positive rate of bronchoscopic cytology and tissue biopsy were 86.1% (266/309) and 83.8% (259/309),respectively.Bronchoscopic cytology combined with bronchial biopsy could obviously improve the positive rate to 94.2% (291/309) in lung carcinoma diagnosis.Taking the tissue biopsy histological type as a standard,the cytotyping accuracy for brush method was 85.1%(74/87) in squamous carcinoma,82.4%(108/131) in adenocarcinoma and 100%(11/11) in small cell carcinoma for higher.However,the accuracy in diagnosing poorly differentiated carcinomas was only 12.2% (5/ 41).Conclusion Fiberoptic bronchoscopic brush cytology plays an stable and important role in diagnosing lung carcinomas and histological type determination.However,it has limited use in diagnosing poorly differentiated carcinomas.
3.Epidemiological analysis of brucellosis in Jinan city, Shandong province from 2002 to 2008
Hua-ru, XU ; Cai-yun, CHANG ; Qing-mei, SUI
Chinese Journal of Endemiology 2010;29(5):556-558
Objective To evaluate the epidemiological characteristics of brucellosis in Jinan city and to identify its cause in order to provide evidence for development of specific preventive strategies in the future.Methods Epidemic information of the disease and survey data of brucellosis cases from 2002 to 2008 in the Infectious and Endemic Disease Control Jinan Centre for Disease Control and Prevention were analyzed statistically.Results From 2002 to 2008, 52 cases were diagnosed as brucellosis, among which 39 cases from Zhangqiu city.The incidence rate ranged from 0.02 to 0.10 hundred thousandth from 2002 to 2006, and 0.25 and 0.26 hundred thousandth in 2007 and 2008, respectively. The disease was found each mouth throughout the year, marked with summer peak[38.46%(20/52)]. Patients increased year after year in summer and spring seasons(r = 0.92, P < 0.01) .The disease was most commonly found in 30 - 59 age group[69.23%(36/52)];men women incidence ratio was 1.67: 1.00;farmers accounting for 94.23%(49/52). There were 5 clusters of family outbreak brucellosis, involving 12 cases. Forty five patients contacted with sheep, accounting for 86.54% (45/52). Conclusions Brucellosis epidemic in Jinan is in an upward trend, mainly in summer and spring, elderly and middle-aged men farmers are the majority of patients. Zhangqiu of Jinan city is a key place for prevention and control of brucellosis;source of infection is not completely eliminated, exotic livestock have not been effectively quarantined, practitioners with weak sense of self-protection is the main reason of the epidemic rise.
4.Surface replacement of hip in the treatment of osteoarthrithis of hip
Wei PENG ; Qing CHANG ; Xiaojun CAI ; Guangsen WU
Chinese Journal of Primary Medicine and Pharmacy 2006;0(04):-
Objective To study the therapeutic effect of the hip surface replacement on osteoarthrithis of hip.Methods The clinical data of 5 cases with osteoarthrithis of hip treated by hip surface replacement were retrospectively reviewed.Results Patients were followed up for an average period of 2.1 years(6~28 months).There were no femoral neck fracture,no dislocation,no infection in all patients.The average Harris score was 85.4(48.3 scores before surgery).Postoperatively quality of life improved obviously.Conclusion The therapeutic effect on osteoarthrithis of hip treated by the hip surface replacement is satisfactory,and the quality of patient's life can be improved,espcially for the youth.
5.Multi-resolution Blending Rendering of the Medical Structure
Zhiyong CHANG ; Hou QING ; Xiaoqiang YANG ; Yeying GUI ; Qing CAI
Journal of Biomedical Engineering 2001;18(1):46-49
This paper presents a new medical data visualiz ation method called multi-resolution blending rendering which has been deve lope d for visualizing the large medical volume data sets. Different from those multi -resolution rendering methods which simplify the structures by polygon mesh opt imization technique, the new method uses different resolution levels to represen t different parts of a structure at the same time. So, it can preserve the integ rality of the structure and emphasize the important part of the structure when simplifying the structure. The new method also takes advantage of the good qualit ies of the wavelet transform and constructs the multi-resolution blending model of the structureby orthogonal wavelet transform and transition operator. The experiment proves that our method can effectively simplify the model of the structure, enormously reduce the number of the triangle of the structure and speedup the structure rendering. It is especially suitable for interactive observations on a complex medical structure.
6.Surgical treatment of popliteal aneurysms in 25 patients
Haidi HU ; Chong LIU ; Qing CHANG ; Yanying REN ; Yongchang CAI ; Zhiquan DUAN ; Jian ZHANG ; Shijie XIN
Chinese Journal of General Surgery 2012;(12):985-987
Objective To evaluate surgical therapies in patients with popliteal aneurysms (PA).Method The clinical data of 25 PA patients admitted from January 1988 to January 2012 were retrospectively analyzed.There were 21 men and 4 women,the mean age was (56 ± 16)years.There were 27 PA in these 25 patients,with bilateral PA in 2 cases.The main symptoms were pulsatile mass in the popliteal fossa,limb pain,acute or chronic distal limb ischemia and limb edema.Result In this series 23out of 25 PA cases recieved operations,17 of them were treated with aneurysmectomy and saphenous vein interposition or bypass grafting,4 of them were treated with aneurysmectomy and prosthetic grafts interposition,1 was treated with aneurism ligation and 1 underwent end-to-end anastomosis after aneurysm resection.There was no perioperative mortality.One patient recieved amputation for distal anastomotic thrombosis and severe limb ischemia.The mean follow-up time is (6.5 ± 0.5) years.After 4 years,a right subclavian artery aneurysm was found in a bilateral PA case and treated surgically.Conclusions Early elective surgical treatment is recommended for patients with PA because PA may go rupture or induce dital limb ischemia and these patients may have good outcome after surgical treatment.Long-term follow-up is warranted to detect the new aneurysm formation.
8.Analysis of implementation situation and influencing factors of long-acting reversiblecontraception measures after PAC in 4 068 artificial abortion women
Huifen CAI ; Xiaoyan LIU ; Jiang WANG ; Shan MENG ; Hui WANG ; Jia LIU ; Qing CHANG
Chongqing Medicine 2017;46(24):3378-3380
Objective To explore the implementation situation and influencing factors of long-acting reversible contraception (LARC) after receiving post-abortion care (PAC) in artificial abortion women.Methods According to the demographic characteristics and abortion risks,4 068 artificial abortion women in the family planning clinic of our hospital were classified.The LARC implementation situation after receiving PAC was compared among different characteristic populations.The Chi square test was utilized to analyze the statistical significance of the data by SAS software.Results The LARC rate in young women was 7.9%),which was lower than 27.7% in 19-40 years old women and 11.8% in perimenopausal women;the LARC rate in nulliparous women was 10.6%,which was lower than 27.7% in parous women;the LARC rate in high-risk abortion women was 33.1%,which was higher than 16.6% in low-risk abortion women,these data analysis had statistically significant significance (P<0.05).The LARC rate in ≤ 20 years old women among high-risk abortion women,breastfeeding women,delivery women within three months,cesarean section women within six months and more than three times artificial abortion women was low (< 50%).However,the LARC rate in the scar pregnancy women and more than two times cesarean section women was high (> 80%).Conclusion Young women,nulliparous women and postpartum women in high-risk artificial abortion should be ranked the focus group for PAC consulting.
9.Alstrom syndrome in children:a case report and literature review
Qingxia CAI ; Guoying CHANG ; Yu DING ; Juan LI ; Qing CHENG ; Xin LI ; Jian WANG ; Xiumin WANG ; Yiping SHEN
Journal of Clinical Pediatrics 2017;35(4):278-281
Objective To analyze the clinical feature, diagnosis and treatment of Alstrom syndrome. Method The clinical data of a case of Alstrom syndrome and the result of her ALMS1 sequencing by the two generation sequencing were retrospectively reviewed. Results The 12 year and 10 month old female suffered from dilated cardiomyopathy, obesity, optic nerve diseases, sensorineural hearing loss, high blood glucose and irregular menstruation since one month of birth. Laboratory examination showed she had high testosterone level, hyperglycemia, hyperlipidemia and fatty liver. High-throughput sequencing confirmed there was ALMS1 gene mutation which includes hybrid frameshift mutations of c.5418delC and p.Y1807Tfs*23, and heterozygous nonsense mutation of c.10549C>T and p.Q3517*, and c.5418delC was a new variation reported for the first time. Conclusion Alstrom syndrome is an autosomal recessive genetic disease, which is characterized by multiple organ dysfunction and metabolic syndrome, and can be diagnosed by gene detection.
10.Film dose analysis system and its application in radiotherapy verification.
Shun-guan WANG ; Wen-song HONG ; Chang-qing CAI
Journal of Southern Medical University 2006;26(7):1039-1040
OBJECTIVETo propose a new computer software-based medical image processing technique with high resolution digital scanner for radiotherapy verification.
METHODSUnder the platform of Windows 2000, the software, programmed with Visual C++.NET, was developed according to modular design. All data of the films and the treatment planning system could be processed as images or dose curves for a robust result.
RESULTSMany functions such as data acquisition, automatic analysis and computation and image processing were integrated in the system. Both geometric and dosimetric errors could be calculated at the same time to verify the radiotherapy accuracy.
CONCLUSIONThis system has good accuracy and stability for cost-effective radiotherapy verification.
Film Dosimetry ; instrumentation ; Humans ; Image Processing, Computer-Assisted ; Radiotherapy Dosage ; standards ; Radiotherapy Planning, Computer-Assisted ; methods ; Reproducibility of Results ; Software