1.Urea Combine with Glucocorticoid Treatment of Infancy Hemangioma Associated with Thrombopenia Syndrome
hong-lin, ZHOU ; chang-xian, DONG ; yu-chun, MA
Journal of Applied Clinical Pediatrics 2006;0(23):-
Objective To explore the treatment of hemangioma associated with thrombopenia(Kasabach-Merritte syndrome,KMS) in infant.Methods The clinical manifestation and the therapy of 14 cases patients with KMS in hospital from 2003 to 2006 were collected ang analyzed,the 400 g/L urea(manufactured by ourself)combined with methylprednisolone local injection were used and followed 0.5 to 1.0 year.Results Two in 14 cases were emergency exairesis,7 cases were recurred for several times,12 cases were cured,1 case was improved,1 case was loss the connection.Conclusions It is an ideal therapy method to use the urea combined with glucocorticoid to treat infancy KMS,little trauma,definite effective,low side effect,high cure rate.
2.Expression of hypoxia-inducible factor-1? and aspartyl-(asparaginyl) beta-hydroxylase in missed abortion patients' villi
Chun-Mei MI ; Chang-Ju ZHOU ; Min XUE ; Yi LU ;
Medical Journal of Chinese People's Liberation Army 1983;0(05):-
4 weeks of arrested embryos.The AAH expression was found to have the similar result as HIF-1?'s.Conclusions The expression level of HIF-1? and AAH in villi of missed abortion patients is much lower than that of normal early pregnant women.HIF-1? and AAH have a function of supporting normal pregnancy,so their low expression may be an important cause of missed abortion.
5.Current state of community nurse training in Jilin province and its development orientation
Xiao-Nan ZHOU ; Chun-Yu LI ; Chun-Chang LI ; Yu-Hui GAO ; Ping SHANG ; Cai-Fu LI ; Ren-Shang CUI
Chinese Journal of Modern Nursing 2011;17(10):1117-1120
Objective To understand the current state of community nurses in Jilin Province and its nursing training so as to provide basis for constructing community nursing training system. Methods 583 community nurses from community health care service centers (stations) in three cities of Jilin Province were investigated with cluster random sampling method to acquire their proficiency level of community nursing knowledge and its demand. Results Common basic nursing knowledge was best mastered by community nurses (63.8%), while knowledge about scientific research was worst mastered (13.6%). Community nurses who were young, in low positions, with work experience for 5 to 9 years, mastered the knowledge worse, 42.9% of them did not attend training. The commonest training problem was that the training period was too short (64.6%); the highest demand was common diseases training for the elderly. Conclusions Nursing training is an important way to improve overall quality of community nurses in the light of unbalance status of their quality in our province and training not being put into place.
6.Application of traditional Chinese medicine reference standards in quality control of Chinese herbal pieces.
Tu-Lin LU ; Jin-Ci LI ; Jiang-Yong YU ; Bao-Chang CAI ; Chun-Qin MAO ; Fang-Zhou YIN
China Journal of Chinese Materia Medica 2014;39(1):149-152
Traditional Chinese medicine (TCM) reference standards plays an important role in the quality control of Chinese herbal pieces. This paper overviewed the development of TCM reference standards. By analyzing the 2010 edition of Chinese pharmacopoeia, the application of TCM reference standards in the quality control of Chinese herbal pieces was summarized, and the problems exiting in the system were put forward. In the process of improving the quality control level of Chinese herbal pieces, various kinds of advanced methods and technology should be used to research the characteristic reference standards of Chinese herbal pieces, more and more reasonable reference standards should be introduced in the quality control system of Chinese herbal pieces. This article discussed the solutions in the aspect of TCM reference standards, and future development of quality control on Chinese herbal pieces is prospected.
Drugs, Chinese Herbal
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standards
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Humans
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Medicine, Chinese Traditional
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standards
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Quality Control
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Reference Standards
7.Effects of guizhi fuling capsule on sex hormone levels and breast issue morphology of mammary gland hyperplasia model rats.
Xiu-juan CHANG ; Jun ZHOU ; Shuai ZHANG ; Jian CHEN ; Chun-miao CHEN ; Zhen-zhong WANG ; Wei XIAO
China Journal of Chinese Materia Medica 2014;39(21):4139-4142
OBJECTIVETo research the effects of Guizhi Fuling capsule on sex hormones levels in blood serum and breast issue morphology of hyperplasia of mammary glands model rats.
METHODThe unpregnancy SD rat models of hyperplasia of mammary glands were established by injecting 0.5 mg x kg(-1) benzoate estradiol. After five weeks doses,the effects of Guizhi Fuling capsule 2.0, 1.0, 0.5 g x kg(-1) and Rupixiao tablet 0.5 g x kg(-1) on the changes of papilla diameter, height and breast issue morphology of the naimal models were explored, and sex hormones levels in blood serum were measured.
RESULTGuizhi Fuling capsule can inhibitnipple swell, improve breast tissue morphology pathological profiles of the animal models, and decrease oestradiol (E2) level and increase progesterone (P) level in blood serum.
CONCLUSIONThese results suggested that Guizhi Fuling capsule could, improve mammary gland pathological profiles. Regulating sex hormone levels may be its important mechanism for treatment of hyperplasia of mammary glands.
Animals ; Capsules ; Drugs, Chinese Herbal ; pharmacology ; Female ; Gonadal Steroid Hormones ; blood ; Hyperplasia ; Mammary Glands, Animal ; drug effects ; pathology ; Rats
8.Epidemiological study on pathogens of deep fungal infection
Jun-Min ZHANG ; Li-Yan XI ; Chang-Ming LU ; Chun-Hong ZHOU ; Jun LI ; Xi-Qing LI ;
Chinese Journal of Laboratory Medicine 2001;0(01):-
Objective To investigate the dynamic distribution changes of fungi responsible for the deep infection and antifungal susceptibility to provide a basis for the empirical antifungal treatment.Methods Medical records were reviewed from cases suspectedof deep fungal infection at our hospital from January 1998 to December 2004.3122 isolates of 13 species were analyzed with SPSSll.0.Etest was used for the antifungal susceptibility test.Results Candida albicans was the most commonly isolated organism,while the prevalence of Candida albicans decreased(76.3% vs 66.8%,x~2=34.33,P
9.Systematic Study on the Authentic and Superior Medicinal Herba and GAP of Herba Asari
Chang-Zheng ZHOU ; Zhen-Lu YANG ; Yin LI ; Chun-Shu YANG
China Journal of Chinese Materia Medica 2001;26(5):343-345
Objective: To investigate the methodology of the systematic study on the Authentic and Superior Medicinal Herba and GAP of Herba Asari. Method: The study was made by textual criticism of Herbology, Botany, Palynology, Cytology, Chemistry, Pharmacology, the analytic methods of allozyme and RAPD. Many subjects on the herb were investigated, such as history, botanical origin, routine examination, morphology of pollen, chromosome and karyotype, the content of oil and its pharmacological effects and so on. Result and Conclusion: The methodology of systematic study on the Authentic and Superior Medicinal Herba was provided.According to the results of the systematic study, the GAP of the herb can be made.
10.Isolation and identification of human periodontal ligament stem cells in vitro.
Tao SHEN ; Hui-jun CHANG ; Cong-xiang JIAN ; Yan-chun YANG ; Ji-xiang ZHOU
West China Journal of Stomatology 2011;29(1):71-78
OBJECTIVETo isolate and identify human periodontal ligament stem cells (PDLSC) by improved methods and assess the characteristics of PDLSC ex vivo.
METHODSThe periodontal ligament cells were obtained from the healthy impacted third molars and teeth extracted for orthodontic purposes and used to isolate PDLSC by limiting dilution assay. PDLSC were cultured and expanded in alpha-MEM supplemented with 10% FBS. Colony-forming assay, immunohistochemistry, flow cytometry, osteogenic and adipogenic induction were used to identify PDLSC.
RESULTSThe obtained cells had high colony-forming efficiency and were positive staining for vimentin and negative for pancytokeratin. Flow cytometry revealed that the isolated cells were positive for STRO-1 and CD146 antibodies and most were in the G0/G1 phase of cell cycle. Under specific conditions, they could differentiate to the osteoblast and adipocyte lineages in vitro.
CONCLUSIONLimiting dilution assay is an effective method to isolate PDLSC and the single-cell-derived colonies demonstrate the properties of stem cells in vitro.
Cell Differentiation ; Cell Separation ; Humans ; In Vitro Techniques ; Osteoblasts ; Periodontal Ligament ; Stem Cells