1.Clinical observation on 90 cases of depression after cerebral apoplexy treated by acupuncture regulating governor vessel tongnao
Jun XING ; Lijing CHANG ; Yanjun WANG
International Journal of Traditional Chinese Medicine 2015;(11):981-983
Objective To evaluate the clinical effect of acupuncture in the treatment of depression after stroke. Methods 90 patients with cerebral apoplexy were randomly divided into 2 groups according to the random number table, with 45 cases in each group. Patients in both groups were given routine western medicine treatment, and guided to carry out suitable limb function rehabilitation training. In addition, the control group was given traditional acupuncture treatment, while the treatment group was given the brain acupuncture treatment with tiaodu in addition to the traditional acupuncture treatment. Hamilton depression scale (HAMD) was used to assess the degree of depression, Chinese stroke scale (CSS) was used to evaluate the degree of neurological deficit, and barthel index (BI) was used to evaluate the activity of daily living (ADL). Results After treatment, the treatment group has a lower CSS score than that of the control group (11.38 ± 3.94 vs. 15.16 ± 4.52, t=4.229), and a lower HAMD score than that of the control group (6.25 ± 3.76 vs. 9.32 ± 5.06, t=3.267). Meanwhile, the treatment group has a higher BI score than that of the control group (69.22 ± 7.05 vs. 55.67 ± 6.21; t=9.675, P<0.01). Furthermore, the treatment group has statistically significant higher cure rate than that of the control group (62.2% vs. 33.3%;χ2=6.413, P=0.011). Conclusions Tiaodu brain acupuncture treatment of depression after stroke has obvious clinical curative effect, and is superior to other traditional acupuncture method.
2.Expression of CXCL12-CXCR4 and its association with angiogenesis in pancreatic cancer.
Zuo-xing NIU ; Li-ming FEI ; Chang-liang WANG
Chinese Journal of Oncology 2009;31(4):286-287
Adenocarcinoma, Papillary
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blood supply
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metabolism
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pathology
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Adult
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Aged
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Carcinoma, Pancreatic Ductal
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blood supply
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metabolism
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pathology
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Chemokine CXCL12
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metabolism
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Female
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Gene Expression Regulation, Neoplastic
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Humans
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Lymph Nodes
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metabolism
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Lymphatic Metastasis
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Male
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Microvessels
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pathology
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Middle Aged
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Neoplasm Staging
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Neovascularization, Pathologic
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metabolism
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pathology
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Pancreas
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metabolism
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Pancreatic Neoplasms
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blood supply
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metabolism
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pathology
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Receptors, CXCR4
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metabolism
3.Problems in Degree-oriented Education in Clinical Medicine and Solutions
Minge HE ; Junwu CHANG ; Xiaohui XING ; Huafeng WANG
Chinese Journal of Medical Education Research 2002;0(01):-
In spite of the relative success achieved in degree-oriented education program in clinical medicine during its preliminary trial stage, problems remain in regard to its recognition and understanding, administration policy, testing systems and the quality control. To further improve the Effects of the actual teaching, it is of high importance that we further our understanding, strengthen the administration, consolidate the testing system and implement better supervision of the teaching procedures of the program.
4.Bacterial Infection of MODS Patients in Intensive Care Unit
Wenxiu CHANG ; Yongqiang WANG ; Jian LI ; Yinghong XING ; Shuhua CAO
Chinese Journal of Nosocomiology 2006;0(08):-
OBJECTIVE To comprehend the main pathogens and their drug resistance of multiple organ dysfunction syndrome(MODS) patients in ICU.METHODS We retrospectively analyzed all the bacteria isolated from 40 MODS patients in ICU.RESULTS The number of bacteria strains isolated was 173,92 G-bacteria strains made up 53.18%,60 G+ bacteria strains made up 34.68%,and 21 fungi strains made up 12.14%.The top six were Staphylococcus aureus(23.70%,MRSA was 13.87%),Pseudomonas aeruginosa(14.45%),Acinetobacter baumannii(11.56%),Stenotrophomonas maltophilia(8.67%),Candida tropicalis(8.09%),and Enterococcus faecalis(7.51%).The susceptive rate of S.aureus and Enterococcus to vancomycin was all 100%,the susceptive rate of A.baumannii and Klebsiella pneumoniae to carbapenems was high.64% patients had the multiplicity of infection(MOI) which always linked with long period in ICU,respiratory failure and mechanical ventilation.CONCLUSIONS MODS patients have a high morbility of G+ bacteria,fungi and MOI,most pathogens show multi-resistance to commonly used antibiotics.Strengthening the monitoring of infection and reasonable using antibiotics should be taken.
5.Design and implementation of medical insurance little catalogue warning function in HIS
Xing-Qiang WANG ; Chang-Xing LIU
Chinese Medical Equipment Journal 2017;38(10):45-47,61
Objective To execute medical insurance little catalogue warning in HIS to prevent the doctor from providing medical service beyond medical insurance coverage.Methods Medical insurance little catalogue was established to regulate the boundaries for medical services available for different patients,and corresponding software was embedded into the medical workstation to call medical insurance little catalogue so as to realize warning for the boundaries and reimbursement rate.Results The function decreased the doctor's workload and the patient's cost while enhanced the doctor's efficiency and the doctor-patient relationship.Conclusion The function is easy to realize with high feasibility,and thus is worthy promoting practically.
6.The outcome of monoclonal gammopathy of undetermined significance in elderly patients
Haifei WANG ; Naibai CHANG ; Weiliang WANG ; Hong SHI ; Baoli XING ; Shangyong NING ; Lei PEI ; Xiaodong XU
Chinese Journal of Geriatrics 2010;29(12):989-991
Objective To explore the outcome of monoclonal gammopathy of undetermined significance (MGUS). Methods The data from 14 MGUS patients in our hospital including clinical features, outcome and change of M protein concentration were analyzed retrospectively. Results The MGUS didn't have the clinical manifestations of multiple myeloma (MM), the time of outcome from MGUS to MM was about 4-20 years (mean time, 10 years). The most types of MM were IgA and IgG, 6 cases were IgA type, 6 cases were IgG type and 2 cases were light chain type. The concentration of immune globulin in general showed an upward trend year by year. A few showed fold lines ascend. Conclusions The elevated monoclonal immunoglobulin may develop into MM after many years. We must follow up frequently to avoid error diagnosis and missed diagnosis.
7.Multiple insecticide resistances and kdr mutation of Culex pipiens pallens in north-central Anhui Province
Xing WEI ; Xiaodi YANG ; Xiaoli WANG ; Jiangyan LI ; Yuanyuan WANG ; Hui XIA ; Xuelian CHANG ; Qiang FANG
Chinese Journal of Schistosomiasis Control 2016;28(4):406-410
Objective To understand the status of resistance to multiple insecticides and the frequencies of kdr mutations in Culex pipiens pallens from north?central Anhui Province. Methods From July to September,2014,the C. pipiens pallens mosquito larvae were collected in Huaibei,Bengbu and Chuzhou cities of the north?central Anhui Province and reared to adults. The female adult mosquitoes at 3-5 days post emergence were tested for susceptibility to the four insecticides,namely 0.05%deltamethrin,5%malathion,0.1%bendiocarb and 4%DDT,by using the standard WHO resistance tube bioassay. The detec?tion of the point mutations of the kdr gene at codon 1014 was conducted by PCR and DNA sequencing in the deltamethrin?resis?tant and?susceptible mosquitoes. Results High levels of resistance to all the four insecticides were found in all the three tested populations,although mosquito mortality varied among populations and test insecticides. Among the test insecticides,DDT showed lowest mortality with no significant difference(F=1.027,P>0.05)in all test populations,whereas significantly differ?ent mortalities were observed among populations for the remained three insecticides tested(deltamethrin,malathion,and ben?diocarb)(F = 23.823,33.955,128.841;all P < 0.01). Two types of non?synonymous kdr mutation at codon position 1014 (L1014F and L1014S)were observed. A positive correlation between L1014F mutation frequencies and deltamethrin resistance levels were detected in the three mosquito populations(r2=0.718,P<0.01). Conclusions The observed high levels of resis?tance to multiple?insecticides coupled with the occurrence of medium to high kdr frequencies in populations of C. pipiens pallens could profoundly affect the mosquito vector control programme in China. The local health departments need to strengthen vector dynamic monitoring and implement rational resistance management strategies.
8.The choice of anterior approach for acetabular fractures: a systematic review
Binfei ZHANG ; Shuang HAN ; Wei FAN ; Ning CHANG ; Hu WANG ; Xing WEI ; Pengfei WANG ; Yan ZHUANG
Chinese Journal of Orthopaedics 2017;37(13):801-809
Objective To evaluate the efficacy and safety in the treatment of acetabular fractures via anterior approaches,including ilioinguinal,stoppa,pararectus approach.Methods Systematic literature retrieval was carried out to obtain two-arm and one-arm researches on the treatment of acetabular fractures via any one of the three approaches before May 2017,from pubmed,embase,cochrane library Databases.Data extraction and quality evaluation of studies were performed by 3 investigators independently.A meta-analysis was performed by RevMan 5.3 and Meta-Analyst beta 3.13.Results Totally 22 low to moderate quality studies,including 7 two-arm and 15 one-arm were included.There were 980 patients,including 581 in ilioinguinal approach group,264 in stoppa approach group and 135 in pararectus approach group.Meta-analysis showed the rate of anatomic reduction in stoppa approach was higher than that in ilioinguinal approach (OR=0.58,95%CI:0.36-0.94,P=0.03),which in pararectus approach was higher than that in ilioinguinal approach (0R=2.95,95%CI:1.22-7.10,P=0.02).Compared to the ilioinguinal approach,the operation time in the Stoppa approach was shorter (MD=48.01,95%CI:17.08-78.95,P=0.002),there was no statistically significant difference between pararectus approach and ilioinguinal approach.In addition,there were no statistically significant differences among three approaches in intra-operative blood loss,postoperative functional outcomes and complications.Conclusion The available limited evidence suggests that the rate of anatomical reduction in stoppa and pararectus approach may be higher than ilioinguinal approach.Compared to the ilioinguinal approach,the operation time in the stoppa approach may be shorter.In this field,further rigorous design,baseline parallel,direct comparison controlled studies on this topic are still needed.
9.Evaluation of the accuracy of the fetal weight estimation system in estimating the fetal weight
Ping CHEN ; Jinhua YU ; Yuanyuan WANG ; Cai CHANG ; Wenqiong XING ; Quan JIANG
Chinese Journal of Ultrasonography 2014;23(2):133-137
Objective To evaluate the accuracy of the fetal weight estimation system in terms of estimating the fetal weight.Methods The fetal weight estimation system developed by the Department of Electronic Engineering,Fudan University was applied to estimate the fetal weight in many hospitals,and the differences between the estimated results of the system and the actual weight of newborn fetuses,as well as the accuracy of the estimation system and the traditional estimation methods were compared.Results A total number of 610 cases were employed,with each case including the ultrasound images of fetus before birth,the corresponding measurement data and the newborn weight.The correlation coefficients between the weight of the newborn babies and the fetal parameters,which were measured by the estimation system in terms of the biparietal diameter,the head circumference,the abdomen circumference and the femur length,were higher than those obtained by manual annotations,with improvements of 0.08,0.17,0.09 and 0.05,respectively.The absolute error of the estimated weight of the system with respect to the actual weight was 44 g smaller than those estimated by traditional method,and the variance of the absolute error was 53 g smaller;while the corresponding absolute percentage error was 1.8% lower,and the corresponding variance percentage was 1.5% lower.Conclusions The fetal weight estimation system improves the accuracy of the prenatal ultrasound assessment and provides reliable information to clinical diagnosis.