1.Clinical Observation of Acute Lymphocytic Leukemia with Mediastinal Mass.
In Sil LEE ; Hyo Seop AHN ; Chang Yee HONG
Journal of the Korean Pediatric Society 1984;27(4):343-349
No abstract available.
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
2.Osteosarcoma-Thirteen-Year Experience
Han Koo LEE ; Sang Hoon LEE ; Chang Seop LEE ; Chung Hoon LEE
The Journal of the Korean Orthopaedic Association 1995;30(2):230-236
Osteosarcoma is the most common primary malignant tumor in the orthopaedic field. Recently, the management of osteosarcoma was evolved in many aspects and the improved results were reported in many articles. The purpose of this study is to evaluate the changes of clinical findings and management modalities in osteosarcoma since 1980. We reviewed 127 osteosarcomas managed from 1980 to 1992. The Enneking surgical stage was as follows; stage I 12 cases, stage II 98 cases and stage III 17 cases. They were subclassified into classic(97 cases), parosteal(12 cases), telangiectatic(5 cases), secondary(4 cases), periosteal(2 cases), gnathic(2 cases), high grade surface(1 cases) and undetermined(4 cases). The disease-free survival rate was evaluated for the patients of stage II classic osteosarcomas treated with amputation(27 cases) or limb-salvage operation(23 cases), and average follow up period of them was 49 months. In 27 cases of amputation adjuvant chemotherapy was administered in 23 cases. And in 23 patients treated with limb-salvage operation, neoadjuvant and adjuvant chemotherapy were done in 19 cases and only adjuvant chemotherapy in 2 cases. The clinical changes since 1980 were as follows: (1) The mean duration from symptom onset to diagnosis was decreased gradually from 6.5 months(1980) to 3.1 months(1992). (2) The proportion of curative surgery was increased from 40%(1980) to 87%(1992) in stage I and II. (3) The proportion of limb-salvage operation was rapidly increased upto 88% since 1985. The 5 year disease-free survival rate of stage II classic osteosarcoma was 36% with amputation and 67% with limb-salvage operation.
Amputation
;
Chemotherapy, Adjuvant
;
Diagnosis
;
Disease-Free Survival
;
Follow-Up Studies
;
Humans
;
Osteosarcoma
3.Progressive Cribriform and Zosteriform Hyperpigmentation.
Jung Bock LEE ; Choong Seop HAHN ; Chang Jo KOH ; Jin Soo KANG ; Sung Nack LEE
Korean Journal of Dermatology 1981;19(4):521-525
No abstract available.
Hyperpigmentation*
4.Speckled Lentiginous Nevus.
Choong Seop HAHN ; Jung Bock LEE ; Seung Hun LEE ; Yoon Kee PARK ; Chang Jo KOH
Korean Journal of Dermatology 1981;19(3):353-358
Speckled lentiginous nevus is a clinical variant of nevus-cell nevus first described by Stewart et al. in 1978. It is characterized by small, dark hyperpigmentated speckles superimposed on a tannish-brown background. The speckled areas show varying histologic patterns ranging from nevus incipiens to junctional or compound nevus. The back ground shows histologic features of Ientigo simplex. Recently, we observed clinical and histological features of 5 cases of speckled lentiginous nevi. The age of onset ranges from birth to infancy, The locations are face, thigh, back and scapula. One has zosteriform distribution in upper extrernity, chest and back. Histologic features of speckles are junctional or compound nevus. We suggest that the origin of dark speckles may be from the tannish-brown background, lentigo simplex.
Age of Onset
;
Lentigo
;
Nevus*
;
Parturition
;
Scapula
;
Thigh
;
Thorax
5.Scrotal Epididymal Anatomy In Hydrocele And Hernia.
Jae Shin PARK ; Chang Woo SEO ; Eun Seok LEE ; Kyung Seop LEE
Korean Journal of Urology 2000;41(5):633-638
No abstract available.
Hernia*
6.Clinical Study of Wilms' Tumor .
Myung Hyun LEE ; In Sil LEE ; Hyo Seop AHN ; Chang Yee HONG
Journal of the Korean Pediatric Society 1984;27(6):603-609
No abstract available.
Wilms Tumor*
7.Correction of severe foot deformity using ilizarov external fixator.
In Ho CHOI ; Duk Yong LEE ; Chin Youb CHUNG ; Jin Sup YEOM ; Chang Seop LEE
The Journal of the Korean Orthopaedic Association 1992;27(3):611-624
No abstract available.
External Fixators*
;
Foot Deformities*
;
Foot*
8.Clinical Usefulness of Arbekacin.
Infection and Chemotherapy 2016;48(1):1-11
Arbekacin is a broad-spectrum aminoglycoside used to treat methicillin-resistant Staphylococcus aureus (MRSA). Arbekacin has antibacterial activities against high-level gentamicin-resistant Enterococci, multidrug-resistant Pseudomonas aeruginosa, and Acinetobacter baumannii et al. Here, we reviewed in vitro data on arbekacin in Staphylococci and Gram-negative microorganisms. We also reviewed clinical studies for clinical efficacy and microbiologic efficacy data in patients with identified MRSA and suspected MRSA infections. The overall clinical efficacy ranged from 66.7% to 89.7%. The microbiologic efficacy rate ranged from 46.2% to 83%. In comparative studies between arbekacin and glycopeptides, arbekacin was similar to other glycopeptides with respect to clinical and microbiological efficacy rates. Combination trials with other antibiotics suggest that arbekacin will be a promising strategy to control Enterococcus spp. multi-drug resistant P. aeruginosa. The major adverse reaction was nephrotoxicity/hepatotoxicity, but patients recovered from most adverse reactions without any severe complications. Based on these results, arbekacin could be a good alternative to vancomycin/teicoplanin in MRSA treatment. Finally, therapeutic drug monitoring is recommended to maximize clinical efficacy and decrease nephrotoxicity.
Acinetobacter baumannii
;
Anti-Bacterial Agents
;
Drug Monitoring
;
Enterococcus
;
Glycopeptides
;
Humans
;
Methicillin-Resistant Staphylococcus aureus
;
Pseudomonas aeruginosa
9.A Clinical Observation on the Incidence of Childhood Leukemia.
Hyo Seop AHN ; Il Soo HA ; Soon Ki KIM ; Hoan Jong LEE ; Chang Yee HONG
Journal of the Korean Pediatric Society 1988;31(7):841-849
No abstract available.
Incidence*
;
Leukemia*
10.Three Cases of Congenital Hypoplastic Anemia.
Heui Jeong KWON ; Myung Hyun LEE ; Jung Hwan CHOI ; Hyo Seop AHN ; Chang Yee HONG
Journal of the Korean Pediatric Society 1985;28(8):829-835
No abstract available.
Anemia, Hypoplastic, Congenital*