1.Degenerative Cervical Myelopathy: Pathophysiology and Current Treatment Strategies
Sung Hoon CHOI ; Chang-Nam KANG
Asian Spine Journal 2020;14(5):710-720
Chronic compression or ischemia of the spinal cord in the cervical spine causes a clinical syndrome known as cervical myelopathy. Recently, a new term “degenerative cervical myelopathy (DCM)” was introduced. DCM encompasses spondylosis, intervertebral disk herniation, facet arthrosis, ligamentous hypertrophy, calcification, and ossification. The pathophysiology of DCM includes structural and functional abnormalities of the spinal cord caused by static and dynamic factors. In nonoperative patients, cervical myelopathy has a poor prognosis. Surgical treatments, such as anterior or posterior decompression accompanying arthrodesis, arthroplasty, or laminoplasty, should be considered for patients with chronic progressive cervical myelopathy. Surgical decompression can prevent the progression of myelopathy and improve the neurologic status, functional outcomes, and quality of life, irrespective of differences in medical systems and sociocultural determinants of health. The anterior surgical approach to the cervical spine has the advantage of removing or floating the intervertebral disk, osteophytes, and ossification of the posterior longitudinal ligament that compress the spinal cord directly. The posterior surgical approach to the cervical spine is mainly used for multisegment spinal cord compression in patients with cervical lordosis. In this review article, we addressed the pathophysiology, clinical manifestations, differential diagnosis, and treatment options for DCM.
2.The influence of the fistula blood flow on the fistula patency after internal arteriovenous fistula.
Chang Nam KIM ; Won Hyun CHO ; Joong Shin KANG
Journal of the Korean Surgical Society 1992;42(4):525-532
No abstract available.
Arteriovenous Fistula*
;
Fistula*
3.Brown-Séquard Syndrome and Cervical Vertebral Fractures after Blunt Cervical Trauma in a Traffic Accident - A Case Report -.
Seung Pyo SUH ; Won Rak CHOI ; Chang Nam KANG
Journal of Korean Society of Spine Surgery 2017;24(4):252-256
STUDY DESIGN: Case report OBJECTIVES: To report a case of Brown-Séquard syndrome after blunt cervical trauma. SUMMARY OF LITERATURE REVIEW: Brown-Séquard syndrome is a rare disease characterized by hemisection of the spinal cord, and it shows the best prognosis of the various types of incomplete spinal cord injuries. MATERIALS AND METHODS: A patient with Brown-Séquard syndrome that occurred after a traffic accident was followed up for 2 years and 6 months. RESULTS: We observed normal recovery of motor strength, but sensory impairment and deep tendon hyperreflexia remained. CONCLUSIONS: Brown-Séquard syndrome is known to have a good prognosis, but in this case, the neurological abnormality did not fully recover; therefore, we report this rare case and present a review of the literature.
Accidents, Traffic*
;
Cervical Vertebrae
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Female
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Humans
;
Prognosis
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Rare Diseases
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Reflex, Abnormal
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Spinal Cord
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Spinal Cord Injuries
;
Tendons
4.The Effect of Saponin on the Na+ - K+ Activated ATPase of Cattle Lens Epithelial Cell.
We Gon CHANG ; Kwang Lim KOO ; Byung Nam KANG
Journal of the Korean Ophthalmological Society 1992;33(1):60-67
The effect of saponin on the Na+ - K+ ATPase of anterior capsule and epithelium of cattle lens has been investigated. The experiment also designed to determine the cation of saponin on the Na+ - K+ ATPase activity in anterior capsule and epithelium of cattle lens. The following results are observed. 1. The Na+ - K+ ATPase activity of cattle lens epithelial cell membrane is inhibited by low concentration of saponin, but increased by high concentration. The strongest activity showed at the dose of 50mg% saponin concentration. 2. The activating effect of saponin on the cattle epithelial cell membrane Na+ - K+ ATPase activity is inhibited by ouabain, but the stimulation of the Mg++ ATPase by high concentration of saponin is not inhibited by ouabain. 3. The activity ratio of Na+ - K+ ATPase by high concentration of saponin is increased by raising the sodium concentration but decreased by raising the potassium concentration. 4. The Na+ - K+ ATPase activity is increased by small amount of calcium but completely inhibited by over 5mM concentration of calcium.
Adenosine Triphosphatases*
;
Animals
;
Calcium
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Cataract
;
Cattle*
;
Epithelial Cells*
;
Epithelium
;
Membranes
;
Ouabain
;
Potassium
;
Saponins*
;
Sodium
5.A Case of Atrichia with Papular Lesions.
Oong KIM ; Chang Nam OH ; In Kyung KANG ; Kyu Chul CHOI
Korean Journal of Dermatology 1995;33(1):150-153
Artichia with papular lesions is a rare congenit,al disease characteriezed by the association of alopecia and papular lesions. We report a case of atrichia with papular lesions in 12-year-old. Alopecia of the scalp and eye brows were present at birth. Nurnerous papular lesions are presentation the trunk, buttock and inguinal area. The histopathologic iinding of a papular lesion showed ker till-filled cyst, and eruptive vellous hair cyst. The patient showed reticulat.ed hyperpigmentation on the hands and feet in addition to the characteristic feature of atriclia with papular lesions.
Alopecia
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Buttocks
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Child
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Foot
;
Hair
;
Hand
;
Humans
;
Hyperpigmentation
;
Parturition
;
Scalp
6.Osteochondritis Dissecans of Both Knee Joints
Chung Nam KANG ; Ki Hong CHOI ; Chang Teok PARK
The Journal of the Korean Orthopaedic Association 1976;11(2):250-254
A case of osteochondritis dissecans of both knee joints is developed in 15 year old boy. Since the original articles of Paget, Koning and others were reported, many theories as to etiology and pathogenesis have been proposed but exact cause has been unknown. Many Joint may show evidence of osteochondritis dissecans but lateral aspect of medial femoral condyle of knee is by far the most frequent site. Under the diagnosis of osteochondritis dissecans of both knees with clinical symptoms and X-ray finding, the one was treated with excision of framents and curettage, and the other treated with drilling of fragments. In follow up study for one year, the result was good without any complaints.
Curettage
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Diagnosis
;
Follow-Up Studies
;
Humans
;
Joints
;
Knee Joint
;
Knee
;
Male
;
Osteochondritis Dissecans
;
Osteochondritis
7.Reconstruction of Posterior Cruciate Ligament Using Semitendinosus Tendon (3 cases)
Chung Nam KANG ; Jin Man WANG ; Ki Hong CHOI ; Chang Nam OH
The Journal of the Korean Orthopaedic Association 1982;17(4):746-750
It is generally accepted that the integrity of posterior cruciate ligament plays a major role in knee stability. The rotatory movement is around a point to the back of center of joint where the posterior cruciate ligament lies, and it is a structure which is just as important as the other ligaments. Methods of reconstruction have been described, using semitendinosus tendon, gracilis tendon, popliteus tendon, patellar tendon, iliotibial band, and medial meniscus. We have successfully used the semitendinosus tendon in two patients who sustained neglected rupture of posterior cruciate ligament.
Humans
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Joints
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Knee
;
Ligaments
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Menisci, Tibial
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Patellar Ligament
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Posterior Cruciate Ligament
;
Rupture
;
Tendons
8.No title available in English.
Whan Nam KANG ; Kee Hyun NAM ; Chi Young LIM ; Hang Seok CHANG ; Cheong Soo PARK ; Jan Dee LEE
Korean Journal of Endocrine Surgery 2005;5(1):43-45
No abstract available.
9.The Irritancy of Hand Dishwashing Liquids on the Skin.
Kang Seok LEE ; Seong Jun SEO ; Myeung Nam KIM ; Chang Kwun HONG ; Byung In RO
Annals of Dermatology 1999;11(1):13-18
BACKGROUND: The regular use of soaps and synthetic detergents has been associated with skin dryness and aggravation of dermatological conditions. OBJECTIVE: Our purpose was to investigate the irritancy of 10 hand dishwashing liquids on normal skin. METHODS: The skin changes, responding to repeat patch testing with 10 hand dishwashing liquids, were measured by visual scoring. RESULTS: The results are summarized as follows; 1. Of the 16 healthy volunteers 8 had reactions. 5 women and 3 men, but there was no significant difference in irritancy between men and women. 2. The mean irritancy scores of the 10 hand dishwashing liquids ranged from 0.06 to 0.88. 3. A prominent increase in the degree of erythema in the first 24 hour patch test did not persist beyond exposure day 5, but after day 5, augmented responses of the erythema and scales, even fissuring occurred. 4. The pH of the test solutions of the hand dishwashing liquids ranged from 5.0 to 6.0, but there appeared to be no correlation between pH and irritancy in the dishwashing liquids tested. CONCLUSION: Our data suggests that regular exposure to hand dishwashing liquids may cause disturbances of the skin in a substantial proportion of individuals, and workers should use hand dishwashing liquids in lower concentrations than recommended and only for short periods with protective measures.
Detergents
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Erythema
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Female
;
Hand*
;
Healthy Volunteers
;
Humans
;
Hydrogen-Ion Concentration
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Male
;
Patch Tests
;
Skin*
;
Soaps
;
Weights and Measures
10.A case of idiopathic progressive atrophoderma of pasini and pierini.
Chang Nam OH ; Yong Joo KIM ; In Kyung KANG ; Kyu Chul CHOI
Korean Journal of Dermatology 1992;30(6):920-923
Idiopathic progressive atrophoderma of Pasini and Pierini(IPAPP) is charcterized by sharply dermatcated, atrophic and slate-gray to brownish patches. We report a 17-year-old female with well-defined, atrophic, and brown colored patched on the abdomen, flank, and back. Histologic finding showed marked thining of dermis with thichening of collagen fibers and fragmentation of elastic fibers.
Abdomen
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Adolescent
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Collagen
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Dermis
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Elastic Tissue
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Female
;
Humans