1.Dose escalation of domestic nedaplatin used in concurrent chemoradiotherapy for cervical cancer.
Wei-Guo ZHU ; Chang-Hua YU ; Tao LI
Chinese Journal of Oncology 2011;33(7):525-526
Adult
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Aged
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Antineoplastic Agents
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administration & dosage
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adverse effects
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therapeutic use
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Carcinoma, Squamous Cell
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therapy
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Chemoradiotherapy
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Diarrhea
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chemically induced
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Dose-Response Relationship, Drug
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Female
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Humans
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Leukopenia
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chemically induced
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Middle Aged
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Organoplatinum Compounds
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administration & dosage
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adverse effects
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therapeutic use
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Radiotherapy, Conformal
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Thrombocytopenia
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chemically induced
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Uterine Cervical Neoplasms
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therapy
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Vomiting
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chemically induced
3.Preliminary Discuss on Identification and Characterization of One Decolorizing Fungus
Hong-Chang LIANG ; Ying-Hua QIAN ; Qing-Hua ZHANG ; He-Miao CHEN ; Xiao-Yu WU ;
Microbiology 2008;0(07):-
According to morphological and microscopic characteristics, a high-efficient decolorizing fungus, the strain Asaw117, was identified as Aspergillus awamori. Selecting eight different dyes from Azo dyes, anthraquinones dyes and oxygen Quinones dyes, the decolorizing assays of various dyes showed that the strain Asaw 117 was the highest decolorizing potential to 0.1 g/L Vat Blue RSN, the discoloration rate up to 100 percent. Comparing to different kinds of medium and several of carbon and nitrogen sources, the strain had the best decolorizing efficient although grew slower in the Czapek medium, otherwise, grew quicker and decolorizing efficient lower in the PDF medium. It could use Vat Blue RSN as a nitrogen source, but not as a carbon source. The medium composing of saccharose and ammonium nitrate as carbon and nitrogen sources was decolorizing potential markedly during different combinations of carbon and nitrogen sources. So the strain has good potential for the dyeing wastewater treatment
4.Research on repairing facial nerve injury of rabbits by neural stem cells and autologous fasia
Chang-xiang YAN ; Yi-hua AN ; Jun-hua LI ; Shuling LIU ; Hong WAN ; Chunjiang YU ; Zhongcheng WANG
Chinese Journal of Rehabilitation Theory and Practice 2004;10(1):21-22
ObjectiveTo observe the effect on repairing facial nerve injury of rabbits by neural stem cells and autologous fasia. Methods22 rabbits with transected facial nerve were divided into 2 groups randomly, control group (8 rabbits,15 sides totally), which transected facial nerve were wrapped by autologous fasia, and treament group (14 rabbits, 20 sides totally), which were wrapped by neural stem cells and autologous fasia. Six weeks after transplantation, neuro-electrophysiological test, immunohistochemical examination were done. The number and thickness of myelin in the re-connected area of transected facial nerve were observed. ResultsThe transplanted animals recovered much better than that in control group (P<0.05). Immunohistochemical examination showed a great deal of BrdU positive cells around the re-connected area of transected facial nerve. Immunohistochemical staining also found plenty of regenerative myelins in this area in the treatment group. While in control group, there were no BrdU positive cells and only a few of regenerative myelins in the same area. ConclusionTransplantation of neural stem cells combined with autologous fasia might become the new method to treat facial nerve injury.
5.Effects of survivin gene siRNA on the growth of gastric cancer cell line
Shao-Chang JIA ; Chang-Qing SU ; Wei-Bing ZHANG ; Yue-Hua WANG ; Yong-Zhong YU ;
Chinese Journal of General Surgery 2000;0(12):-
Objective To construct an expression plasmid carrying the specific siRNA of survivin gene,and to evaluate its silencing effect on the expression of survivin gene and its inhibition effect on the growth of gastric cancer cells.Methods The specific siRNA of survivin gene was designed and synthesized,and an expression plasmid pAdGFP-siRNA was constructed.Gastric cancer cell line SGC-7901 was cuhured and transferred with pAdGFP-siRNA,then the silencing of survivin gene expression and the growth inhibition of cancer cell mediated by pAdGFP-siRNA were identified.Results The growth of gastric cancer cells was inhibited after transferring the pAdGFP-siRNA,with the inhibition rate of 68.2% compared to the control group.Immunohistochemistry showed that the specific siRNA markedly silenced the expression of survivin gene in cancer cells.Conclusions The overexpression of survivin gene in gastric cancer cells results in the high proliferation and the resistance to the chemo- and radio-therapy of the cancer cells.The specific siRNA can markedly silence the expression of survivin gene and inhibit the growth of cancer cells.
6.Effect of Cutaneous Never Anastomosis on Sensory Reconstruction in Free Anterolateral Femoral Flap Repairing Wide Spreadly Dorsal Hand Soft Tissue Defect
Li-ke CHEN ; Bo WU ; Si-hua CHEN ; Chang-yu TANG ; Xian-pei ZHOU ; Yu XU
Chinese Journal of Rehabilitation Theory and Practice 2015;21(7):845-848
Objective To explore the effect of cutaneous never anastomosis on sensory recovery in repairing wide spreadly soft tissue defects in dorsal hand with free anterolateral femoral flap. Methods The cases with wide spreadly soft tissue defects in dorsal hand repaired with free anterolateral femoral flap from January 2006 to December 2012 were divided into 2 groups. The control group including 15 consecutive patients from January 2006 to January 2009, whose sensation was reconstructed in routine way. Other 15 consecutive patients from Febnary 2009 to December 2012 were as research group, whose sensation was reconstructed with the suture of cutaneous nevers of anterolateral femoral flaps and forearm. All the patients were followed up for 12~24 months. Results All the free flaps survived in both groups. There were 4 cases good of sensory recovery in the control group, and it was 11 in the research group. No ulceration happened. Conclusion Cutaneous never anastomosis may result in satisfactory sensory function in the patients with wide spreadly soft tissue descts in dorsal hand repaired with free anterolateral femoral flap.
7.Occlusion the posterior semicircular canal using laser for treatment the complex benign paroxysmal positional vertigo.
Shun-Zhang LIN ; Ai-hua SUN ; Shu-Chang TIAN ; Peng-Yu CAO
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2005;40(1):77-77
Female
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Humans
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Laser Therapy
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methods
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Middle Aged
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Semicircular Canals
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surgery
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Vertigo
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etiology
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surgery
8.A few questions on the major collateral of stomach.
Yu-Shan FAN ; Xiao-Che FENG ; Tao LIANG ; Chang-Hua TANG ; Fu-Rui MIAO
Chinese Acupuncture & Moxibustion 2014;34(3):300-302
It is held by some of the researches that the "16 collaterals" is composed of the "15 collaterals" and "the major collateral of stomach". And it is included into the textbook that Xuli, the major collateral of stomach, is the pulsation point at the cardiac region. Xuli is often explained as the empty portion of the human body by many researches. Through analysis and summarization of the related theory of the major collateral of stomach, the above mentioned opinion is discussed. And the understanding on the major collateral of stomach is deepened. As a result, it is concluded that count the major collateral of stomach into the 16 collaterals together with the 15 collaterals is inadvisable. The real pulsation point at the cardiac region locates under the left breast. And the real meaning of Xuli is "extending in all directions".
Acupuncture
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history
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China
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Collateral Circulation
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History, Ancient
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Humans
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Medicine in Literature
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Meridians
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Stomach
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blood supply
9.Angiomyolipoma of the kidney with lymph node involvement.
Chuan-Zhen WU ; Feng-Hua WANG ; Cheng-Mei LI ; Wen-Chang FANG ; Jia-Ni YU
Chinese Journal of Pathology 2005;34(11):715-715
Adrenalectomy
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Adult
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Angiomyolipoma
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pathology
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surgery
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Follow-Up Studies
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Humans
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Kidney
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pathology
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Kidney Neoplasms
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pathology
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surgery
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Lymph Node Excision
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Lymph Nodes
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pathology
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Lymphatic Metastasis
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Male
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Nephrectomy
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Ureter
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surgery
10.Comparison of the intraocular pressure value measured with Goldmann applanation tonometer and non-contact tonometer
Qi-Chang, YAN ; Yu-Hua, HE ; Quan-Hao, BAI ; Yue, DI ; Xi-Ling, WANG
International Eye Science 2006;6(3):537-539
AIM: To assess the relative agreement of GAT and NCT in IOP measurement by comparing the differences between Goldmann applanation tonometer (GAT) and non-contact tonometer (NCT) in intraocular pressure (IOP) detection.METHODS: IOP of 529 eyes of 265 volunteers were measured with both NCT and GAT, respectively.RESULTS: The measurement results of NCT were lower than that of GAT, there was significant difference between the IOP measured with NCT and GAT (19.13 vs23.43, t=22.644, P<0.05). With the increasing of IOP values, the difference magnitude was greater, especially in IOP group that was more than 30mmHg, but the correlation coefficient became lower.CONCLUSION: The measurement results with NCT are lower than that of GAT. When the IOP with the NCT is in borderline value, it need be corrected with GAT, in order to discover the pathologically elevated IOP and avoid the misdiagnosis and mistreatment of glaucoma.