1.Analysis of bacterial drug resistance of bloodstream infections in Fujian in 2021
WU Quan-ming ; CHEN Fa-lin ; WU Chang-sheng
China Tropical Medicine 2022;22(12):1194-
Abstract: Objective To understand the distribution and drug resistance of pathogenic bacteria of bloodstream infection
in Fujian Province, and to provide reference for clinical rational drug use. Methods Bacteria identification and antimicrobial
susceptibility test were carried out on the isolated strains of blood culture samples in 31 medical institutions in Fujian Province
according to the unified plan. The data were statistically analyzed by WHONET 5.6 software according to the Clinical and
Laboratory Standards Institute (CLSI) drug sensitivity executive standard in 2021. Results After removing the duplicate
strains, 10 356 strains of bacteria were collected, including 3 668 strains of Gram-positive bacteria (35.4%) and 6 688 strains
of Gram-negative bacteria (64.6%). The top 5 bacteria are Escherichia coli, Klebsiella pneumoniae, coagulase negative
Staphylococcus, Staphylococcus aureus and Pseudomonas aeruginosa. In this study, the detection rate of methicillin-resistant
Staphylococcus aureus (MRSA) was 24.5%, and the detection rate of methicillin-resistant coagulase-negative Staphylococcus aureus (MRCNS) was 76.8%. Vancomycin, teicoplanin and linezolid resistant staphylococci were not found. The detection rate
of penicillin resistant Streptococcus pneumoniae was 3.2%. Vancomycin resistant Enterococcus faecalis and Enterococcus
faecium were 0.8% and 1.1% respectively. The resistance rate of Escherichia coli to carbapenems was 0.8%, and the resistance
rate to levofloxacin was 41.9%; the resistance rate of Klebsiella pneumoniae to carbapenems was 15.0%. The resistance rate of
Acinetobacter baumannii to carbapenems was 45.1%; the detection rate of Pseudomonas aeruginosa was only 14.2%, and it
maintained a high sensitivity to most drugs. Conclusions Most bloodstream infections in Fujian Province are caused by
Escherichia coli, Klebsiella pneumoniae and Staphylococcus. The drug resistance of some strains is not optimistic, so we should
continue to strengthen the clinical application management of antibiotics and use them correctly and reasonably.
Keywords: Bloodstream infection; bacteria; antibiotics; drug resistance monitoring
2.The development and application of a continuous passive motion instrument
Gang WU ; Chang-Jie ZHANG ; Chang-Fa TANG ; Wei-Xiong CHEN ;
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(07):-
Objective To validate if the continuous passive motion instrument we developed is practical and sta- ble for animal experiment.Methods Ten New Zealand male rabbits were used to establish the animal model of full- thickness defect of articular cartilage in the facies patellaris of femur with their both knees.The rabbits were then randomly divided into groups A and B(10 in each group).The rabbits in group A were administered with CPM of both knees daily for 4 weeks,while those in group B remained normal cage activity only.At the end of the treatment,all the animals were sacrificed,and their articular cartilage was harvested for HE staining and observation.Results It was found that group A had a significantly better repair of the full-thickness defects of articular cartilage than that of the group B,as reflected by the range of motion and morphological observation of the knees(P
3.Leves of Tumor Necrosis Factor Alpha,Interleukin-1 Beta,Interleukin-6 in Serum and Cerebrospinal Fluid in Children with Intracranial Infection
fa-guang, MU ; ying, OU-YANG ; chang-hui, CHEN ; jian-bo, ZHANG
Journal of Applied Clinical Pediatrics 1986;0(01):-
Objective To investigate the fuction of tumor necrosis factor alpha(TNF-?),interleukin-1 beta(IL-1?) and interleukin-6(IL-6) in children with intracranial infection.Methods TNF-?,IL-1? and IL-6 levels of serum and cerebrospinal fluid(CSF) were determined in the purulent meningitis group(25 cases),tuberculous meningitis group(17 cases),viral meningitis group(30 cases)and control group(20 cases)by enzyme-linked immunosorbent assay(ELISA).Results The levels of TNF-?,IL-1? and IL-6 obviously increased in CSF compared with that in the serum (Pa
4.Application of SEMG to study the effects of imagery training on back-style high jump.
Wen-Feng LIU ; Yong-Ling CHANG ; Chang-Fa TANG ; Zhen-Zhen HONG ; Li-Qin YIN ; Jin CHEN ; Wen-Ning REN ; Long JIANG ; Jian KUANG
Chinese Journal of Applied Physiology 2013;29(3):260-270
Adolescent
;
Adult
;
Athletic Performance
;
psychology
;
Back
;
physiology
;
Electromyography
;
Exercise
;
physiology
;
Humans
;
Imagery (Psychotherapy)
;
Male
;
Young Adult
5.Delorme procedure for full-thickness rectal prolapse: a report of 25 cases.
Chao-wen CHEN ; Geng ZHANG ; Chang-hong YAN ; Chang-fa WANG
Chinese Journal of Gastrointestinal Surgery 2012;15(3):285-287
OBJECTIVETo evaluate the use of Delorme procedure for full-thickness rectal prolapse.
METHODSA series of 25 patients with full-thickness rectal prolapse were treated by Delorme procedure in four institutions between March 2005 and June 2010. The clinicopathological data were analyzed retrospectively.
RESULTSThere were 9 males and 16 females. The mean age was 52(46-72) years old. All the procedures were successfully performed. There were no perioperative deaths. The mean operative time was 65(45-150) min. The intraoperative bleeding was 58(20-200) ml. The mean length of hospital stay was 8.5(5-14) days. Anastomosis dehiscence occurred in 1 patient at post-operative day 7 who was managed under anesthesia. Minor complications occurred in 8(32%) patients, including urinary retention(n=3), intractable pain(n=1), and bowel obstruction(n=4). The follow up time ranged from 2 to 6 years with a median of 3.5 years. Prolapse recurrence was observed in 1(4%) patient during the follow up. The remission rates of fecal incontinence, constipation, bleeding were 37.5%(6/16), 45.5%(5/11), and 15.4%(2/11), respectively. The Wexner incontinence score significantly decreased (median, 5.0 vs. 9.0, P<0.01). The resting pressure and maximum squeeze pressure increased significantly after surgery, while the initial volume and maximal tolerance volume decreased significantly(All P<0.01).
CONCLUSIONSDelorme procedure is safe and easy to perform. The anorectal function is improved after surgery. Therefore it should be considered the procedure of choice for rectal prolapsed.
Aged ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Rectal Prolapse ; surgery ; Retrospective Studies ; Treatment Outcome
6.Validation of the Chinese Version of the Schizophrenia Cognition Rating Scale
Kuan-Wei HUANG ; Pao-Yen LIN ; Yu LEE ; Yu-Chi HUANG ; Chi-Fa HUNG ; Sheng-Yu LEE ; Chih-Ken CHEN ; Liang-Jen WANG
Psychiatry Investigation 2022;19(7):511-518
Objective:
The Schizophrenia Cognition Rating Scale (SCoRS) is an interview-based assessment tool for evaluating the cognitive deficit and daily functioning of patients with schizophrenia.
Methods:
Sixty-eight patients with schizophrenia and 68 age- and sex-matched healthy individuals were recruited to validate the Chinese version of SCoRS in this study. All participants underwent cognitive assessment using the SCoRS, which was verified by the Brief Assessment of Cognition in Schizophrenia (BACS), and the UCSD Performance-based Skills Assessment, Brief Version (UPSA-B). Patients with schizophrenia were additionally assessed using the Positive and Negative Syndrome Scale (PANSS).
Results:
SCoRS ratings reported by patients (SCoRS-S), those reported by the interviewer (SCoRS-I), and SCoRS global scores (SCoRS-G) showed significant correlation with all subscales of the BACS and the UPSA-B. On receiver operating characteristic curve analysis, SCoRS-S, SCoRS-I, and SCoRS-G significantly differentiated patients with schizophrenia from healthy controls. Moreover, SCoRS-S and SCoRS-I ratings showed positive correlation with the negative symptoms and general symptoms of PANSS.
Conclusion
The Chinese version of SCoRS showed good discriminant, concurrent, and external validity, suggesting that it is a useful and convenient tool for assessment of cognitive function among Mandarin-speaking patients with schizophrenia in clinical practice.
7.Clinical analysis of a family with familial hemangioblastoma
Ye-Shuai HU ; Jun YANG ; Shun-Chang MA ; Jian-Fa QI ; Ji-Jun LIANG ; Zhi-Qiang LI ; En-Hao CUN ; Yong-Kai CHANG ; Su-Hua CHEN
Chinese Journal of Neuromedicine 2011;10(12):1270-1273
Objective To analyze the clinical and imaging features of a family(3 patients)with familial hemangioblastoma,and their diagnosis and prognosis.Methods The detailed data about clinical and imaging features of all patients diagnosed as familial hemangioblastoma,admitted to our hospital from October 2004 to May 2010,were analyzed,and the lesions of other regions,besides the tumor lesion,were observed.Results No lesions of other regions were noted in these 3 patients.Cranial MRI showed that 2 had cystic and solid tumor and 1 had solid tumor;,total removal was performed on these patients under microscope; regular follow-up was given and no recurrence was noted.Conclusion Familiar hemangioblastoma is serious hereditary disease; and MRI is the most important detective method; microsurgical operation is the most important therapy.Early diagnosis and treatment should be given to the patients with familiar hemangioblastoma due to its high recunence rate,having difficulty in operation and its trend to combining with other lesions of the other parts.
8.Manage orbital apex lesions via posterior lateral orbitotomy.
Xi-Yue WU ; Shu-Fa ZHENG ; Chang-Zhen JIANG ; Chen-Yang WANG ; De-Zhi KANG ; Jin FU
Chinese Medical Journal 2012;125(19):3598-3599
Adolescent
;
Adult
;
Female
;
Humans
;
Male
;
Middle Aged
;
Orbit
;
pathology
;
surgery
;
Orbital Neoplasms
;
surgery
;
Retrospective Studies
;
Young Adult
9.Value of preoperative barium contrast examination for the diagnosis and operative planning in gastric cancer.
Chang-jian WANG ; Guang-fa ZHAO ; Qing-guo LI ; Jing-gui CHEN ; Kai ZHU ; Ying-qiang SHI ; Hong FU
Chinese Journal of Gastrointestinal Surgery 2010;13(4):270-272
OBJECTIVETo investigate the value of preoperative barium contrast examination for the diagnosis and operative planning in gastric cancer.
METHODSClinical data of 229 gastric cancer patients were analyzed retrospectively. Lesions were divided into three parts: the cardiac, the body, and the antrum. The diagnostic accuracy of localization and the extent of tumor between gastroscopy alone and gastroscopy plus barium contrast were compared with the results of surgical findings.
RESULTSThe diagnostic accuracy of localization and the extent of tumor for gastroscopy in the cardiac, the body and the antrum cancers were 100% and 78.4%, 94.6% and 86.5%, 98.1% and 84.6%, respectively, while for gastroscopy plus barium contrast were 100% and 84.8%, 100% and 91.9%, 99.0% and 90.4%, respectively. The diagnostic accuracy of both the localization and the extent of tumor were not significantly different between gastroscopy alone and gastroscopy plus barium contrast (P>0.05). Diagnostic accuracy of the length of esophagus infiltrated by cardiac cancer in gastroscopy was 60.6%, while in gastroscopy plus barium contrast was 90.9%, which was significantly different (P<0.05). Gastroscopy plus barium contrast was more accurate in predicting the possibility of thoracotomy in cardiac cancer infiltrating the lower esophagus.
CONCLUSIONSIt is necessary to perform preoperative barium contrast examination in cardiac cancer patients, so as to identify whether the lower esophagus is infiltrated and to measure the length of lesion, which can provide evidences for making a decision of thoracotomy. For gastric body and antrum cancer, there is no indication for barium contrast examination if gastroscopy findings are satisfied.
Adenocarcinoma ; diagnostic imaging ; pathology ; surgery ; Barium ; Contrast Media ; Female ; Humans ; Male ; Middle Aged ; Radiography ; Retrospective Studies ; Stomach Neoplasms ; diagnostic imaging ; pathology ; surgery
10.Catheter Ablation of Peri-Conduit Ventricular Tachycardia in a Patient with Rastelli Procedure for Double Outlet Right Ventricle with Malposition of Great Arteries.
Abigail Louise D TE ; Fa Po CHUNG ; Chin Yu LIN ; Atul PRABHU ; Pi Chang LEE ; Shih Ann CHEN
Korean Circulation Journal 2017;47(4):534-535
No abstract available.
Arterial Switch Operation*
;
Arteries*
;
Catheter Ablation*
;
Catheters*
;
Double Outlet Right Ventricle*
;
Humans
;
Tachycardia, Ventricular*