An unusual case of primary cutaneous anaplastic large cell lymphoma induced by influenza vaccination is reported.A 79-year-old man developed an erythematous nodule at the injection site on the upper left arm 2 months after vaccination against influenza A virus,which gradually grew and ulcerated.Pathological examination of the lesion revealed epidermal infiltrate of lymphocytes and numerous clumps of densely distributed lymphocytes with lightly stained cytoplasm,nuclear atypia and karyokinesis.Immunohistochemistry showed that the tumor cells stained positive for CD3 (90％),CD5 (90％),LCA (90％),CD30 (90％),CD10 (a few),Ki-67 (80％),but negative for CD20,CD56,cytokeratin 1-3,epithelial membrane antigen,synaptophysin,and anaplastic lymphoma kinase.The patient was diagnosed with primary cutaneous anaplastic large cell lymphoma at the injection site following vaccination against influenza A virus.

Objective To create a stable,reliable and cheap rat model of intra-abdominal hypertension(IAH)by simulating the development of secondary IAH after overdose resuscitation for severe hemorrhagic shock.Methods Sixteen adult male SD rats were randomly divided into sham group and portal vein stenosis group,with eight rats in each group.Portal vein stenosis group had transabdominal separation of portal vein with constant stenosis,while sham group underwent simple laparotomy and dissection of portal vein.Abdominal binding and hemorrhagic shock by drawing blood through the femoral artery cannulation with mean arterial pressure(MAP)of 40 mm Hg(1 mm Hg=0.133 kPa)for two hours were performed in two groups.Then,reinfusion of all autologous blood and continuous infusion of sodium lactate Ringer's solution were performed to induce IAH.Results In the portal vein stenosis group,IAH models were successfully built in all the rats except that one rat died after ligation of portal vein.The success rate of modeling was 87.5％,with total time of(4.68±0.53)hours and total solution infusion of(597.33±75.03)ml/kg.No successful modeling was obtained in the sham group.Conclusion High success rate and good reproducibility of IAH models can be achieved by fluid resuscitation after constant portal vein stenosis,abdominal binding and hemorrhagic shock with mean MAP of 40 mm Hg for two hours.

AIM: To establish the quality control standard for Chuanbaizhiyang Lotion(Radix Sophorae Flavescentis, Cacumen Tamaricis, Fructus Cuidii, etc.). METHODS: Radix Sophorae Flavesentis, Fructus Cnidii, Folium Artemisiae Argyi were identified by TLC. The content of osthole was determined by HPLC. RESULTS: The TLC sports developed was fairly clear. The HPLC showed good repeatability. The average recovery of osthole was 96.72% with RSD of 1.04%. CONCLUSION: The method is simple, accurate and can effectively control the quality of Chuanbaizhiyang Lotion.

Bilingual teaching is a positive exploration of raising high quality talented persons under the new situation.It exists some problems in local college bilingual teaching such as the shortage of teachers,standard teaching materials,proper students level,management measures and so on.Local colleges should strengthen training the teachers,vigorously introduce the talented persons;do well the bilingual teaching material construction through many ways,teach students in accordance with their aptitude, standardize management and establish the scientific teaching appraisal mechanism.

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains a curable method for hematological malignancies.Nearly all transplant candidates have donor with the successful application of haploidentical SCT.This article summarized some reports on donor selection,prophylaxis and treatment of graft-versus-host disease,and graft failure in the 58th American Society of Hematology Annual Meeting to present the progress of allo-HSCT in treating hematological malignancies.

Objective To understand the preventive medicine students' education demand and effectiveness evaluation to train handling skills of public health critical incidents, to analyze the education problems, and to look for countermeasures to meet the demand for the talents. Methods The investigation was conducted in 105 students of preventive medicine major from two universities whose questionnaire included the handling public health critical incidents knowledge, public health critical incidents knowledge demand, education evaluation and so on. Results All the students believed that it was essential to handle knowledge of public health critical incidents. 78.1 percent of students believed that it was important to master knowledge of public health critical incidents for improving their competitiveness. 84.8 percent of students thought it inadequate to have textbook knowledge only. 75.2 percent of students held the professional training should be strengthened. Conclusions The current education programs are unable to meet the students' demand for knowledge on handling public health critical incidents and lack the relevant contents. The education organizations are supposed to reform preventive medicine education model, to increase the content of courses, and to prolong training duration. The pertinent knowledge of public health critical incidents should also be integrated into the training programs for students.

Objective To evaluate the value of Bolus chase technology for angiography of lower extremity. Methods 12 cases with diabetes foot or leg pain were examined with Bolus chase technology. Results Low extremity artery thrombosis was found in 12 cases. Conclusion Bolus chase technology is better than standard DSA in the display of lower extremity vessel.

Fourier Transform plays a very important part on spatialization and reconstruction of MRI. Advanced mathematic analysis makes us understand the concept of Fourier Progression and Fourier Transform, and some concrete applications of Fourier Transform on the MRI are listed.

Aim To observe the action of estrone on the hippocampal neuronal apoptosis induced by NMDA in vitro and to analyse the mechanism underlying the neuroprotection of estrone. Methods The methods of both morphological analysis and cell viabilities were used, and Western blot was also used to analyce the role of antitoxiciy of estrone. Results The cultures were conformed with fluorescent dye of Hoechst 33258 and NeuN. About 31.6% neurons were induced into apoptosis by NMDA(300 ?mol?L~ -1 +glycine 5 ?mol?L~ -1 ,compared with control group, P0.05). MTT test also showed that estrone can protect cultures from apoptosis induced by NMDA, it can raise the cell viabilities exposed to NMDA. Western blot showed that activities of caspase-3 can be inhibited by estrone, the segments of caspase-3 can diminished after application of estrone together with NMDA. Conclusion Estrone had neuronal protection, this role maybe relate to the inhibition of caspase-3, a common pathway in apoptosis. The results can provide some clues to the explovation of the clinical use of estrone and to the development of a neuronal protective drug.