1.Shigellosis - Pathogenesis and Current Epidemics.
Chul Hun Ludgerus CHANG ; Geun Am SONG ; Bok Kwon LEE
Korean Journal of Clinical Microbiology 1999;2(2):118-124
No abstract available.
Dysentery, Bacillary*
2.The Experimental Study for the Reaction of the Hemostatic Agents to the Surrounding Brain Tissue.
Heon Sang CHANG ; Kwan Tae KIM ; Shi Hun SONG ; Seong Ho KIM ; Youn KIM
Journal of Korean Neurosurgical Society 1991;20(10-11):900-904
In a series of 20 young rats, three cortical lesions were made in each hemisphere. Two of these lesions were filled with avitene and gelfoam, while the third was left empty as a control. The animals were killed successively on weeks 1, 2, 4 and 8 after the operation. The results were as follows : 1) Although there was no difference in the type of tissue reactions, avitene was more rapid and profound than gelfoam in the process and degree of inflammatory reaction at the same periods. 2) Avitene biodegradaded more rapidly than gelfoam. 3) The extent of fibrosis and adhesion to the surrounding brain tissues were not grossly different between these two agents but more profound histopathologically in avitene at the same periods. With these results, we could conclude that the avitene was superior to the gelfoam as the hemostatic agent in neurosurgical area.
Animals
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Brain*
;
Collagen
;
Fibrosis
;
Gelatin Sponge, Absorbable
;
Rats
3.A Case of Cutaneous Horn of the Penis Associated with Squamous Cell Carcinoma.
Seok Hun HONG ; Seong Jun SEO ; Chang Kwun HONG ; Kye Yong SONG ; Byung In RO
Annals of Dermatology 1993;5(2):137-140
Cutaneous horns of the penis are rare. We report a case associated with squamous cell carcinoma in a 56-year-old male. A gradually enlarging nodule had been on the glans penis for four years. He had suffered from an erythematous crusted tumor mass and horny excrescence on the glans penis which recurred and was aggravated after excision of the nodule seven months ago. Histopathologic findings of the lesions showed characteristic findings of squamous cell carcinoma and cutaneous horn. In situ DNA hybridization for human papillomavirus types 6, 11, 16, 18, 32, and 33 were all negative. The tumor mass were surgically excised and we have not found any sign of recurrence since then.
Animals
;
Carcinoma, Squamous Cell*
;
DNA
;
Epithelial Cells*
;
Horns*
;
Humans
;
Male
;
Middle Aged
;
Penis*
;
Recurrence
4.An Obstetric aspects of RDS of Preterm Infants in Kwang-Ju and Chon-nam.
Dong Won KIM ; Sang Ki PARK ; Jong PARK ; Chang Hun SONG
Korean Journal of Obstetrics and Gynecology 1999;42(12):2754-2760
OBJECTIVES: This study was performed to evaluate obstetric aspects and epidemiologic data of respiratory distress syndrome(RDS) in premature baby(under 37 gestational weeks). We compared the mortality and incidence of RDS in premature baby according to gestational age, birth weight, infant sex, mode of delivery. In addition, this study was searched for demonstrating the influence of hypertensive mother, and effectiveness of surfactant and corticosteoid administration. METHODS: A study was conducted for 2,360 premature baby under 37gestatinal weeks, who were born at four main hospitals in Kwangju and Chonnam from January 1, 1995 to December 31, 1997. Data were collected from hospital records and was analyzed by SPSS computer program. RESULTS: 1. The total incidence of RDS among all the preterm infants under 37gestational weeks, who were admitted in NICU of four hospitals was 22.7%. 2. Neonatal mortality was decreased as the gestational age and or birth weight advanced. (p<0.001) 3. There was no difference in the incidence of RDS according to sex and mode of delivery. (p>0.005) 4. The mortality of RDS infants in this study was 28.1%. 5. There was no statistical correlation between neonatal mortality and use of surfactant. 6. Corticosteroids administration to preterm mother did not decrease the incidence of RDS, but, there was no statistical significance due to insufficient study group. 7. The incidence of RDS among the babies of hypertensive mother was 21.0%. CONCLUSION: Still the RDS in premature baby is the most common cause of perinatal death in this country. In our study, the incidence and mortality of RDS in prematue baby was mainly depends on gestational age of infants. Therefore, we suggested that prevention of preterm labor is the important to decrease the incidence and mortality of RDS.
Adrenal Cortex Hormones
;
Birth Weight
;
Female
;
Gestational Age
;
Gwangju*
;
Hospital Records
;
Humans
;
Incidence
;
Infant
;
Infant Mortality
;
Infant, Newborn
;
Infant, Premature*
;
Jeollanam-do
;
Mortality
;
Mothers
;
Obstetric Labor, Premature
;
Pregnancy
5.A Survey on the Mode of Working of Estheticians in OECD Member Nations andSome Asian Countries in Relation to Medical Service.
Chan Woo JEONG ; Seung Kyung HANN ; Chang Hun HUH ; Hae Jun SONG
Korean Journal of Dermatology 2008;46(9):1149-1154
In 2008, Korea has enacted new ordinances about the role of estheticians, but this law can be interpreted ambiguously, restricting hiring of estheticians in medical clinics. The purpose of the study is to obtain information about medical-esthetic systems in other countries. We have taken a survey of this object from 30 OECD & Asian countries, and the questionnaires returned from a total of 22 countries (Australia, Austria, Canada, Denmark, Finland, France, Germany, Hungary, Japan, Netherlands, New Zealand, Norway, Portugal, Slovak Republic, Spain, Switzerland, Turkey, United Kingdom, United States, Singapore, Israel, and Thailand), were used for the final analysis. The results are summarized as follows. In most countries, estheticians working independently deal with only healthy, normal skin. In most countries, estheticians working independently have no right to operate any medical instruments. In all 17 countries that returned the questionnaires medical clinics can employ estheticians, and only theses estheticians who belong to the medical clinics can handle the non-invasive medical instruments under the supervision of doctors. In 17 countries that have related legal regulations, nurses, under the control of doctors, can perform wider range of duties in various settings than estheticians. The survey concludes that the duties of estheticians are closely related with medical skin care services and estheticians can perform various non-invasive medical procedures only under the control of doctors. From consulting a variety of medical-esthetic systems in other countries, we propose that the estheticians be allowed to work in medical clinics to provide better medical services for the patients and to make more chances of employment for themselves.
Asian Continental Ancestry Group
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Austria
;
Canada
;
Denmark
;
Employment
;
Finland
;
France
;
Germany
;
Great Britain
;
Humans
;
Hungary
;
Israel
;
Japan
;
Jurisprudence
;
Korea
;
Netherlands
;
New Zealand
;
Norway
;
Organization and Administration
;
Portugal
;
Questionnaires
;
Singapore
;
Skin
;
Skin Care
;
Slovakia
;
Social Control, Formal
;
Spain
;
Switzerland
;
Turkey
;
United States
6.A Study of Preterm Infants Care in Kwang-Ju and Chon-nam(I).
Kyung LEE ; Hyun Ju MOON ; Sang Ki PARK ; Jong PARK ; Chang Hun SONG
Korean Journal of Obstetrics and Gynecology 1999;42(11):2502-2506
OBJECTIVE: To investigate the preterm labor & preterm infants care in Kwangju and Chonam. METHODS: A study was conducted for 2,360 newborns who were born at four main hospitals in Kwangju and chonam from January 1, 1995 to December 31, 1997. Data were collected by review of hospital records. RESULTS: 1. The survival rate was 6.90% at 23~34 weeks, 38.60% at 27~28weeks and 90.67% after 31wks. 2. The survival rate divided according to birth weight were 8.89% below 1,000gm, 57.14% in 1,001~1,500gm, 86.75% in 1,501~2,000gm and 93.37% over 2,000gm respectively. 3. Clinical causes of neonatal death were RDS(48.84%) hyperbilirubinemia (20.74%), sepsis(11.95%) and pneumonia(9.67%). 4. Incidence of RDS was 23.22% and it's neonatal mortality was 36.28%. CONCLUSION: The survival rate of preterm birth in Kwang-Ju and Chon-nam was still lower than data from advancing countries, and main cause of neonatal death was respiratory distress syndrome.
Birth Weight
;
Female
;
Gwangju*
;
Hospital Records
;
Humans
;
Hyperbilirubinemia
;
Incidence
;
Infant
;
Infant Mortality
;
Infant, Newborn
;
Infant, Premature*
;
Obstetric Labor, Premature
;
Pregnancy
;
Premature Birth
;
Survival Rate
7.The Effects of Propofol on the Contraction in the Rat Uterine Smooth Muscle.
Kyung Hee OH ; Tae Hun AN ; Jong Dal JUNG ; Keum Young SO ; Hyung Suk LIM ; Chang Hun SONG
Korean Journal of Anesthesiology 2007;52(1):72-76
BACKGROUND: Propofol is an alternative to thiopental as an intravenous induction agent for cesarean section. It is also used as a sedative for supplementation of regional blockade during cesarean section. It has been reported that propofol relaxes not only vascular smooth muscle but also other smooth muscles. The aim of this study was to investigate the effect of propofol on rat uterine smooth muscle in an isolated preparation in the rat. METHODS: Uterine smooth muscle tissues were obtained from rats (n = 21). The muscle strips were suspended in tissue baths and isometric tension was recorded. After spontaneous or oxytocin induced activity had been accomplished in the buffer solution as a control, propofol (1 to 20microgram/ml) in fat emulsion was applied cumulatively to the bath and the effects were continuously recorded. RESULTS: In vitro, propofol induced a dose-dependent inhibition of spontaneous as well as oxytocin induced myometrial contractile activity. Propofol concentration of 1microgram/ml had no significant effects on the resting tension, active tention, and frequency of contraction developed by spontaneous and oxytocin induced uterine contractility. However, Complete muscular relaxations on spontaneous and oxytocin induced contractility were obtained at a concentration of 10microgram/ml and 20microgram/ml, respectively. CONCLUSIONS: Propofol inhibits spontaneous and oxytocin-induced uterine smooth muscle contractions in dose dependent pattern.
Animals
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Baths
;
Cesarean Section
;
Female
;
Muscle, Smooth*
;
Muscle, Smooth, Vascular
;
Oxytocin
;
Pregnancy
;
Propofol*
;
Rats*
;
Relaxation
;
Thiopental
8.Bowel Stricture Caused by Acute Ischemic Colitis after Intraaortic Balloon Counterpulsation.
Hyun Seog LEE ; Tae Hun KIM ; Yong Bum CHO ; Chan Il MOON ; Jae Woong CHOI ; Chang Seob SONG
Korean Circulation Journal 1999;29(12):1373-1373
Intraaortic balloon counterpulsation (IAB) has been shown to prolong survival in the critically ill cardiac patients. Originally developed for use in the patients with cardiogenic shock, the indications have been expanded. But despite technical advances, the complication rate associated with IAB remains high. The most commonly reported complications include damage to the femoral artery and distal embolization. Other reported major complications are balloon rupture, limb loss, bleeding, systemic infection and bowel infarction. We report a patient complicated by ischemic colitis causing stenosis and intestinal obstruction after IAB insertion.
Colitis, Ischemic*
;
Constriction, Pathologic*
;
Counterpulsation*
;
Critical Illness
;
Extremities
;
Femoral Artery
;
Hemorrhage
;
Humans
;
Infarction
;
Intestinal Obstruction
;
Rupture
;
Shock, Cardiogenic
9.H9N2 avian influenza virus in Korea: evolution and vaccination.
Dong Hun LEE ; Chang Seon SONG
Clinical and Experimental Vaccine Research 2013;2(1):26-33
Low pathogenic avian influenza (LPAI) H9N2 viruses have been circulating in the Eurasian poultry industry resulting in great economic losses due to declined egg production and moderate to high mortality. In Korea, H9N2 LPAI was first documented in 1996 and it caused serious economic loss in the Korean poultry industry, including layer and broiler breeder farms. Since then, the H9N2 viruses that belong to the Korea group have been prevalent in chickens and have continuously evolved through reassortment in live bird markets. To control LPAI outbreaks, since 2007, the Korean veterinary authority has permitted the use of the inactivated oil adjuvant H9N2 LPAI vaccine. Although only oil-based inactivated vaccine using the egg-passaged vaccine virus strain (A/chicken/Korea/01310/2001) is permitted and used, several new technology vaccines have been recently suggested for the development of cost-effective and highly immunogenic vaccines. In addition, several different differentiation of infected from vaccinated animals (DIVA) strategies have been suggested using appropriate vaccines and companion serologic tests for discriminating between naturally infected and vaccinated animals. Recent reports demonstrated that the Korean LPAI H9N2 virus underwent antigenic drift and evolved into distinct antigenic groups and thus could escape from vaccine protection. Therefore, improved vaccination strategies including periodic updates of vaccine seed strains are required to achieve efficient control and eradication of LPAI H9N2 in Korea. Further, vaccination should be part of an overall integrated strategy to control the disease, including continued nation-wide surveillance, farm biosecurity, and DIVA strategy.
Animals
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Birds
;
Chickens
;
Disease Outbreaks
;
Friends
;
Humans
;
Influenza A Virus, H9N2 Subtype
;
Influenza in Birds
;
Korea
;
Ovum
;
Poultry
;
Seeds
;
Serologic Tests
;
Sprains and Strains
;
United Nations
;
Vaccination
;
Vaccines
;
Viruses
10.Clinical Analysis of External Ventricular Drainage in the Treatment of Intraventricular Hemorrhage.
Chang Myung CHOI ; Shi Hun SONG ; Youn KIM
Journal of Korean Neurosurgical Society 1990;19(1):45-51
A series of 54 adult patients with intraventricular hemorrhage(IVH) diagnosed by computed tomography(CT) scan and treated with external ventricular drainage were reviewed. In cases who occurred poor drainage of bloody cerebrospinal fluid obstruction, irrigation with urokinase solution(6,000 U/ml) was tried. Hypertension and ruptured aneurysms accounted for 65% of the cases. Although most cases showed poor prognosis, we experienced dramatic improvements in four comatose patients who had fixed dilated pupils after spontaneous intraventricular hemorrhage with secondary acute hydrocephalus. We believe ventriculostomy to be effective in managing IVH especially in the early stage before cerebral herniation occurs. This procedure, accomplished by a convenient and relatively simple technique, led to evacuration of intraventricular blood, or the temporary or permanent cessation of progression of the hydrocephalic process, decrease in ventricular size, and normalization of ICP. However, a relatively high incidence of infection was problematic.
Adult
;
Aneurysm, Ruptured
;
Cerebrospinal Fluid
;
Coma
;
Drainage*
;
Hemorrhage*
;
Humans
;
Hydrocephalus
;
Hypertension
;
Incidence
;
Prognosis
;
Pupil
;
Tomography, X-Ray Computed
;
Urokinase-Type Plasminogen Activator
;
Ventriculostomy