1.Bednar Tumor: A case report with discusion of histogenesis.
Korean Journal of Pathology 1993;27(6):659-662
The authors examined a case of Bednar tumor(pigmented dermatofibrosarcoma protuberans). A 35-year-old woman presented with protruding black back mass 3x2.5 cm in surface dimension and 1 cm in heigh, which has grown slowly for 30 years. Microscopically the lesion is characterized by spindle cells arranged in storiform pattern and admixed with melanin containing dendritic cells. Ultrastructural study revealed three cell populations: (1) cells resembling fibroblasts, (2) cells resembling perineural cells, and (3) melanocytes. The immunohistochemical study using S-100 protein alpha-1 antitrypsin, antichymotrypsin and EMA revealed negative reaction in spindle fibroblastic tumor cells. The histogenesis of this neoplasm remains controversial; neuroectoderm, perineural cell, fibroblast and histiocyte. Through the ultrastructural study and immunohistochemical study, the authors suggested that Bedner tumor arises form the neuroectoderm with bidirectional to perineural and fibroblastic differentiation.
Female
;
Humans
2.Plication of redundant rectal mucosa in hemorrhoidectomy.
Chang Yong SONG ; Jung Moo LEE
Journal of the Korean Society of Coloproctology 1992;8(2):151-155
No abstract available.
Hemorrhoidectomy*
;
Mucous Membrane*
3.Improved Quality of Life (QOL) During the Off-treatment Intervals of the Intermittent Androgen Deprivation (IAD) in the Prostate Cancer Patients.
Chang Myon PARK ; Song Soo JEON ; Han Yong CHOI
Korean Journal of Urology 2000;41(9):1063-1070
No abstract available.
Humans
;
Prostate*
;
Prostatic Neoplasms*
;
Quality of Life*
5.Baculovirus-mediated Expression of p35 Confers Resistance to Apoptosis in Human Embryo Kidney 293 cells
Jian-hua, SONG ; Chang-yong, LIANG ; Xin-wen, CHEN
Virologica Sinica 2007;22(5):389-396
Baculovirus has many advantages as vectors for gene transfer. We demonstrated that recombinant baculovirus vectors expressing p35 (Ac-CMV-p35) and eGFP (Ac-CMV-GFP) could be transduced into human kidney 293 cells efficiently. The level of transgene expression was viral dose dependent and high-level expression of the target gene could be achieved under the heterogonous promoter. MTT assay suggested that both Ac-CMV-p35 and Ac-CMV-GFP did not have cytotoxic effect on human embryo kidney 293 cells. Cell growth curve showed the Ac-CMV-p35 and Ac- CMV-GFP transduced and non-transduced cells had similar proliferation rate, so baculovirus-mediated p35expression had no adverse effect on cell proliferation. In addition, baculovirus-mediated p35 gene expression protected human embryo kidney 293 cells against apoptosis induced by various apoptosis inducers such as Actinomycin D, UV or serum-free media. These results suggested that the baculovirus vector mediated p35 gene expression was functional and it could be widely used in molecular research and even gene therapy.
6.Total Hip Arthroplasty on Paralytic Hips: Two Case Report on Poliomyelitic and Cerebral Palsied Hips
Duk Yong LEE ; Ho Sung SONG ; Jay Suk CHANG
The Journal of the Korean Orthopaedic Association 1981;16(4):927-936
We performed total hip arthroplasty on a young male adult with paralytic dislocation of the hip due to poliomyelitis. Because of extreme shortening, as well as instability and weakness, the patient was unable to bear weight on the limb. Pastoperative course was complicated by ectopic ossification that compromised the hip and knee motion. Another young male adult with severe spastic cerebral palsy underwent total hip arthroplasty because of an intractable pain due to degenerative arthritis. Initial attempt coupled with adductor tenotomy and obtuator neurectomy ended in gross loosening and acetabular protrusion. Revision consisted of extensive soft tissue release and bone grafting of acetabular defect and use of a protrusion cup and an extra-long stem. Postoperative course was complicated by long-standing serous aseptic discharge from the wound which was controlled by antibiotics and prolonged recumbency. Indications for total hip arthroplasty in paralytic hips are rare and should be reserved for the most crippling conditions and one must be prepared fvr technical difficulties and a variety of complications with a prospecs for less than optimum results.
Acetabulum
;
Adult
;
Anti-Bacterial Agents
;
Arthroplasty, Replacement, Hip
;
Bone Transplantation
;
Cerebral Palsy
;
Dislocations
;
Extremities
;
Hip
;
Humans
;
Knee
;
Male
;
Ossification, Heterotopic
;
Osteoarthritis
;
Pain, Intractable
;
Poliomyelitis
;
Spectinomycin
;
Tenotomy
;
Wounds and Injuries
7.A Case of Malignant Transformation of Gastric Tubular Adenoma Proven by 9-year Follow-Up.
Kyoo Wan CHOI ; Yong Il KIM ; In Sung SONG ; Chung Yong KIM ; Hyun Chae JUNG ; Dong Kyung CHANG ; Sang Yong SONG
Korean Journal of Gastrointestinal Endoscopy 1994;14(4):450-457
The association of gastric tubular adenoma and adenocarcinoma is already well known. Then, are those two pathologic lesions merely incidentally coexisting or does the one evolve to the other? That is a longstanding controversy. Nowadays, as is the case with the colonic tubular adenoma, the hypothesis that gastric tubular adenoma may be a precancerous lesion is generally accepted. However the direct evidences are rare. We report a clear case proving the potential of direct malignant transformation of gastric tubular adenorna through the 9-year close endoscopic follow-up. The developed cancer is well differentiated, surrounded with background tubular adenoma and limited to the submucosal layer.
Adenocarcinoma
;
Adenoma*
;
Colon
;
Follow-Up Studies*
8.A Cases of Nevus Sebaceus of Jandassohn Associated with Tubular Apocrine Adenoma.
June CHANG ; Myeung Nam KIM ; Kye Yong SONG ; Byung In RO ; Chin Yo CHANG
Korean Journal of Dermatology 1990;28(1):103-106
The nevus sebaceus of Jadsssohn is an organoid nevus generally noted on the scalp or the face as a single lesion. A 26-year-old man has suffered from a pea sized, pedunculated cherry red colored papule on the back ground of yellowish colored verrucous plaque on the vertex. Clinically, pedunculated papule was similar to granuloma pyogenicum, but histopathologic examination showed the features of tubular apocrine adenoma with focal areas of syringocystadenoma papilliferum, suggesting that might be a variant or could be associated with syringocystadenoma papilliferum.
Adenoma*
;
Adult
;
Granuloma, Pyogenic
;
Humans
;
Nevus*
;
Nevus, Sebaceous of Jadassohn
;
Organoids
;
Peas
;
Prunus persica
;
Scalp
9.A Case of X - linked Ichthyosis.
Yoon Whoa CHO ; Chang Kwun HONG ; Kye Yong SONG ; Byung In RO ; Chin Yo CHANG
Korean Journal of Dermatology 1990;28(3):368-372
We report a case of X-linked ichthyosis in a 19 year-old male patient who has been covered with brown to black colored thick scales on the lateral aspect of chest, upper abdomen and inner aspect of both extremities since one month at, birth. Histopathologic findings showed hyperkeratosis and papillomatosis with normal granular cell layers in the epidermis. On electron microscopy, multilayered keratins with increased melanosomes in the stratum corneum were noted. In his family, his cousin is also affected by the same disease.
Abdomen
;
Epidermis
;
Extremities
;
Humans
;
Ichthyosis*
;
Male
;
Melanosomes
;
Microscopy, Electron
;
Papilloma
;
Parturition
;
Thorax
;
Weights and Measures
;
Young Adult
10.A clinical study of core decompression for osteonecrosis of the femoral head.
Suk Hyun LEE ; Won Yong SHON ; Jae Suk CHANG ; Wuk Song CHANG ; Kyung Wuk RHA
The Journal of the Korean Orthopaedic Association 1993;28(1):62-69
No abstract available.
Decompression*
;
Head*
;
Osteonecrosis*