1.Imbalance in T Lymphocyte Subsets in Erythema Nodosum Leprosum.
Hyang Joon PARK ; Chang Yong CHA ; Woo Hyun CHANG ; Do Il KIM
Korean Journal of Dermatology 1987;25(4):476-485
A study was performed to investigate a relationship between the status of T lymphocyte subsets in the peripheral blood and the pathogenesis of erythema nodosum leprosum (ENL) reactions. T lymphocyte subsets, B lymphocytes and serum immnnoglobulin levels were explored in 40 leprosy patients (10 tuberculoid (TT), 17 lepromatous (LL), and 13 lepromatous with ENL). In patients with LL, suppressor cells increased and helper cell diminished, resulting in a decrease in the helper/suppressor (Th/Ts) ratio to 0.86 + 0.20, as compared with controls (1. 77 + 0.41). But in ENL patients, there was a significant diminution of suppressor cells and an increase of helper cells, resulting in an increase in Th/Ts ratio to 2.08 + 0.30. Four weeks after treatment of ENL, Th/Ts ratio decreased to l.18+ 0.31 again. The mean percentages of B cells and serum immunoglobulin levels in with LL. and ENL increased significantly compared with controls. Only IgG increased in patients with ENL compared with patients with LL. The results in patiients with TT did not differ significantly from those of controls. The findings suggest that cell-mediated immune responses, imbalance in T lymphocyte subsets, may play a role in the pathogenesis of ENL, either directly or by inducing an antibody critical to the formation of the immune complex
Antigen-Antibody Complex
;
B-Lymphocytes
;
Erythema Nodosum*
;
Erythema*
;
Humans
;
Immunoglobulin G
;
Immunoglobulins
;
Leprosy
;
T-Lymphocyte Subsets*
;
T-Lymphocytes, Helper-Inducer
2.Cervical Intervertebral Disc Calcification in Children: A Case Report.
Dong Eun SHIN ; Chang Soo AHN ; Yong Suk CHO
Journal of Korean Society of Spine Surgery 2011;18(4):254-258
STUDY DESIGN: A case report. OBJECTIVES: This case report presents a child who was treated conservatively after having being diagnosed with cervical intervertebral disc calcification. SUMMARY OF LITERATURE REVIEW: Cervical intervertebral disc calcification is considered as a degenerative change of spine. It is common in adults and in most cases, no symptoms are observed. In children, by contrast, it is a rare condition and frequently accompanies symptoms such as severe neck pain and dysphagia. MATERIALS AND METHODS: A 7-year-old male patient who suffered from neck pain and torticollis without trauma had been diagnosed with cervical intervertebral disc calcification and was treated conservatively. He was discharged after symptom relief, and has been followed up and observed in our outpatient department. RESULTS: The improvements of symptom and radiographic findings were found in the month follow up. CONCLUSIONS: Cervical intervertebral disc calcification shows similar symptoms to laryngopharyngeal abscess, traumatic injury and infective spondylitis, but through careful physical examination and radiologic evaluation, differential diagnosis is possible. After diagnosis, conservative treatment alone is sufficient. Antibiotic usage and surgical treatment are avoidable.
Abscess
;
Adult
;
Child
;
Diagnosis, Differential
;
Humans
;
Intervertebral Disc
;
Male
;
Neck Pain
;
Outpatients
;
Physical Examination
;
Spine
;
Spondylitis
;
Torticollis
3.Characterization of monoclonal antibodies against human cytomegalovirus(HCMV) glycoprotein.
Eung Soo HWANG ; Ju Young SEOH ; Chung Gyu PARK ; Yoon Hoh KOOK ; Chang Yong CHA
Journal of the Korean Society for Microbiology 1992;27(6):545-553
No abstract available.
Antibodies, Monoclonal*
;
Glycoproteins*
;
Humans*
4.A Clinical Study on Patients with Mycoplasma Pneumoniae Pneumonia in Childhood.
Yeong Ho RA ; Sung Ho CHA ; Sa Joon CHUNG ; Yong Mook CHOI ; Chang Il AHN
Journal of the Korean Pediatric Society 1987;30(7):759-768
No abstract available.
Humans
;
Mycoplasma pneumoniae*
;
Mycoplasma*
;
Pneumonia*
;
Pneumonia, Mycoplasma*
5.Factors Affecting Dyspnea in Retired Coal Miners in Korea.
Yong Hee CHEON ; Sei Jin CHANG ; Bong Suk CHA
Korean Journal of Occupational and Environmental Medicine 2001;13(3):286-295
OBJECTIVES: This study was done to examine the risk factors for the dyspnea of retired coal miners in Korea. METHODS: Eight hundred and sixteen male workers who took the health examination for retired coal miners in the T hospital were recruited, in this study and their health examination records were employed to assess the risk factors for dyspnea. Both univariate and multiple logistic regression analyses were used to estimate the relationship between known risk factors and the presence of dyspnea. RESULTS: Variables in the univariate analysis, which showed a significant relationship with dyspnea were age(>or=60 years) (OR : 2.20, 95% CI : 1.63-3.00), work duration(>or=2 0 years) (OR : 1.67, 95% CI : 1.24-2.25), profusion of small opacity(>or=1/0) (OR : 1.81. 95% CI : 1.30-2.51), large opacity(>or=A) (OR : 2.19, 95% CI : 1.30-3.70), and the ratio of the distance between the start of the first division of the right and left main pulmonary arteries divided by the transverse diameter of the thorax (cor pulmonale index)(>or=0 . 3 6 ) (OR : 2.37, 95% CI : 1.77-3.17). The multivariate analysis using logistic regression analysis showed age(>or=60 years)(OR : 1.69, 95% CI : 1.28-2.21), smoking amount(>or=1 filters/day) (OR : 1.61, 95% CI : 1.06-2.45), no experience of having quit smoking (OR : 1.40 95% CI : 1.06-1.84), and the cor pulmonale index(>or=0.36)(OR : 1.75, 95% CI : 1.34-2.29) were associated with an increased risk for dyspnea. CONCLUSIONS: These results suggests that the cor pulmonale index is the most significant risk factor in predicting dyspnea in retired coal miners. In addition, this study also revealed that workers aged 60 years or more or smokers were more likely to experience dyspnea as compared to those aged 60 years or less and nonsmokers.
Coal*
;
Dyspnea*
;
Humans
;
Korea*
;
Logistic Models
;
Male
;
Multivariate Analysis
;
Pulmonary Artery
;
Pulmonary Heart Disease
;
Risk Factors
;
Smoke
;
Smoking
;
Thorax
6.Establishment of Measurement of Human Cytomegalovirus with in situ ELISA.
Eung Soo HWANG ; Jin Hee KIM ; Chung Kyu PARK ; Chang Yong CHA
Journal of the Korean Society of Virology 2000;30(2):125-130
No Abstract Available.
Cytomegalovirus*
;
Enzyme-Linked Immunosorbent Assay*
;
Humans*
7.Investigation of antigen related to the in vitro invasiveness of salmonella typhimurium through the Madin-Darby canine kidney(MDCK) epithelial cell monolayer.
Chung Gyu PARK ; Eung Soo HWANG ; Ju Young SEOH ; Yoon Hoh KOOK ; Chang Yong CHA
Journal of the Korean Society for Microbiology 1991;26(6):553-562
No abstract available.
Epithelial Cells*
;
Salmonella typhimurium*
;
Salmonella*
8.A case of paraquat poisoning in child.
Min Yong OUM ; Sung Ik CHO ; Young Chang KIM ; Hak Ju CHA ; Sang Jhoo LEE
Journal of the Korean Pediatric Society 1989;32(11):1540-1545
No abstract available.
Child*
;
Humans
;
Paraquat*
;
Poisoning*
9.A Comparative Study of Therapeutic Effect of Intravenous Gammaglobulin plus Aspirin Versus Aspirin Alone in Kawasaki Syndrome.
Boung Yul LEEM ; Chong Sung CHUNG ; Sung Ho CHA ; Yong Mook CHOI ; Chang Il AHN
Journal of the Korean Pediatric Society 1989;32(10):1408-1415
No abstract available.
Aspirin*
;
Mucocutaneous Lymph Node Syndrome*
10.A case of nephrogenic diabetes insipidus due to vesicoureteral reflux.
Yong Bae SUH ; Jong Yul JEON ; Sung Ho CHA ; Byoung Soo CHO ; Chang Il AHN
Journal of the Korean Pediatric Society 1991;34(9):1299-1304
No abstract available.
Diabetes Insipidus, Nephrogenic*
;
Urinary Tract Infections
;
Vesico-Ureteral Reflux*