1.General Anesthesia for Patient with Broncho-gastric Fistula: A case report.
Kyeong Ah KIM ; Sang Wook HAN ; Chang Weon KIM ; Il Yeong JUNG ; Ho Jo JANG
Korean Journal of Anesthesiology 1997;33(5):988-992
Broncho-gastric fistula caused by benign gastric ulcer perforation after esophagectomy is very rare. In general anesthesia of a patient with broncho-gastric fistula, in spite of hyperventilation, leakage of the anesthetic gases through fistula may make the patient hypercapneic, and positive pressure ventilation may increase the risk of the pulmanary aspiration by the regurgitation of gastric fluid by stomach distension. For that reason, in this patient, denitrogenation was performed during patient's voluntary respiration with 100% oxygen for 5 minutes, and induction was performed without positive pressure ventilation, and one lung ventilation was carried out. Hypoxemia was followed by one lung ventilation because his pulmonary function was moderate obstructive type and his lung was damaged by aspiration of gastric fluid via broncho-gastric fistula. A low level of continuous positive airway pressure (CPAP) has no significant hemodynamic effect and can maintain the patency of nonventilated lung, so hypoxemia induced by one lung ventilation may be reduced. Thus we carried out one lung ventilation with CPAP (10 cmH2O) in nonventilated lung and blocked broncho-gastric fistula with a bronchial blocker for prevention of both regurgitation of gastric fluid and leakage of anesthetic gases. One lung anesthesia was performed without any problem in this case.
Anesthesia
;
Anesthesia, General*
;
Anesthetics, Inhalation
;
Anoxia
;
Continuous Positive Airway Pressure
;
Esophagectomy
;
Fistula*
;
Hemodynamics
;
Humans
;
Hyperventilation
;
Lung
;
One-Lung Ventilation
;
Oxygen
;
Positive-Pressure Respiration
;
Respiration
;
Stomach
;
Stomach Ulcer
2.Hippocampal Volume in Elderly Patients with Major Depressive Disorder.
Sun Wook YOUN ; Chang Hyun KIM ; Byung Jo KANG
Journal of Korean Geriatric Psychiatry 2002;6(2):117-127
OBJECTIVES: Many recent studies of relationship between geriatric depression and changes in brain have examined the structural abnormalities in hippocampus. Using MRI, the hippocampal volumes of patients with major depression were measured and compared with control subjects for research of above relationship. METHOD: Fourteen patients (early-onset five, late-onset nine) with major depressive disorder based on DSM-IV and fourteen age-matched normal controls are included. Applying semiautomated computer program to MRI, we measured and compared the hippocampal volumes in two groups. Moreover we identified the laterality and the correlation of the volumes with age of onset, duration of education, numbers of psychiatric admission, duration of illness, MMSE scores at admission, and severity of depression. RESULT: No significant difference was observed between the hippocampal volumes of patients with major depressive disorder and those of control subjects. A significant correlation in patients was observed between duration of illness and left hippocampal volume to cerebral volume ratio. In early-onset depressed patients, left hippocampal volume was larger than in late-onset depressed patients and the positive correlation was observed between MMSE scores at admission and left hippocampal volume to cerebral volume ratio. In late-onset depressed patients, there was the negative correlation between numbers of psychiatric admission and MMSE scores at admission as well as and between cerebral volume and age of onset. CONCLUSION: Our study indicated no change in the volume of hippocampus among geriatric major depressive patients. So we suggest that more extensive and systematic studies for structural abnormality of hippocampus will be required.
Age of Onset
;
Aged*
;
Brain
;
Depression
;
Depressive Disorder, Major*
;
Diagnostic and Statistical Manual of Mental Disorders
;
Education
;
Hippocampus
;
Humans
;
Magnetic Resonance Imaging
3.An Influence of Modified Robicsek Sternal Wiring after Median Sternotomy on the Postoperative Sternal Wound Infection.
Won Ho CHANG ; Wook Youm DONG ; Hyun KIM ; Hong Chul OH ; Jung Wook HAN ; Hyun Jo KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 2009;42(6):763-769
BACKGROUND: In the majority of cases, sternal instability and wound infection concomitantly present after a cardiac operation following conventional median sternotomy, and these complications have a major influence on the postoperative course. The aim of this study is to compare the results of the different sternal wiring techniques on sternal infection. MATERIAL AND METHOD: Between April 2004 and December 2008, 157 adult patients underwent cardiac operation through a median sternotomy. 86 patients who had undergone standard peristernal wiring were included in group A, whereas 71 patients who had undergone modified Robicsek sternal wiring were included in group B. The incidences of sternal wound complications in the two groups were assessed. RESULT: The mean age of the group B patients was older than that of the group A patients (61+/-10 years vs 57+/-13 years). The incidence of preoperative left ventricular dysfunction (ejection fraction <30%), chronic obstructive pulmonary disease, renal failure requiring dialysis and diabetes mellitus were significantly higher in Group B, whereas the other perioperative risk factors for infection were not significantly different between the two groups. Two patients in group A experienced superficial wound infection, whereas 4 patients in group B displayed superficial wound infection, but the difference was not statistically significant (p=0.255). Yet poststernotomy deep sternal wound infection appeared in 6 patients of group A, whereas none of the patients in group B displayed this malady. CONCLUSION: The modified Robicsek sternal wiring technique showed greater sternal stability even for the patient with a high risk for infection, and the technique caused a lower incidence of deep sternal wound infection.
Adult
;
Diabetes Mellitus
;
Dialysis
;
Humans
;
Incidence
;
Pulmonary Disease, Chronic Obstructive
;
Renal Insufficiency
;
Risk Factors
;
Sternotomy
;
Sternum
;
Ventricular Dysfunction, Left
;
Wound Infection
4.Vacuum-assisted Closure for the Treatment of Lymphorrhea Following Surgery of the Femoral Artery.
Won Ho CHANG ; Wook YOUM ; Hong Chul OH ; Jung Wook HAN ; Hyun Jo KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 2010;43(5):562-564
Lymphorrhea is a common complication after inguinal dissection for exposure of the femoral artery. Injury of the lymphatics occurs frequently because they are anatomically close to blood vessels. Uncontrolled lymph drainage increases postoperative morbidity, and wound infection may follow. Despite current treatment options, lymphorrhea after inguinal dissection is still difficult to manage and results in a prolonged hospital stay. A vacuum-assisted closure device was used in a 72-year-old woman who had lymphorrhea after vascular surgery by groin incision. Vacuum-assisted control for lymphorrhea resulted in earlier closure of the wound and reduced the length of hospital stay.
Aged
;
Blood Vessels
;
Drainage
;
Female
;
Femoral Artery
;
Groin
;
Humans
;
Length of Stay
;
Lymphatic System
;
Negative-Pressure Wound Therapy
;
Wound Infection
5.A Case of Interruption of Aorta with Patent Ductus Arteriosus.
Jae Kyung CHOI ; Chang Hoon JANG ; Ho Joong YOON ; Jong Mok YANG ; Wook Sung CHUNG ; Seung Suk CHUN ; Jae Hyung KIM ; Kyu Bo CHOI ; Soon Jo HONG
Korean Circulation Journal 1991;21(5):914-918
Interruption of the aortic arch is an uncommon congenital cardiovascular malformation invariably accompanied by other cardiovascular anomalies. This carries a 76% mortality rate in the first month of life. We recently experienced a case of interruption of the aortic arch with patent ductus arteriosus in a 21-year-old man with systolic murmur. he did not showed any other symptoms or signs. Cardiac catheterization with angiography showed interruption of the aortic arch with many systemic arterial collaterals and patent ductus arteriosus.
Angiography
;
Aorta*
;
Aorta, Thoracic
;
Cardiac Catheterization
;
Cardiac Catheters
;
Ductus Arteriosus, Patent*
;
Humans
;
Mortality
;
Systolic Murmurs
;
Young Adult
6.Vacuum-Assisted Closure in Treatment of Poststernotomy Wound Infection and Mediastinitis: Three cases report .
Won Ho CHANG ; Kyun HUH ; Young Woo PARK ; Hyun Jo KIM ; Youn Seop JEONG ; Wook YOUM
The Korean Journal of Thoracic and Cardiovascular Surgery 2002;35(2):166-169
Poststernotomy mediastinitis is a rare but potentially life-threatening complication of cardiac surgery. Up to present, poststernotomy wound infection has been treated by closure of wound directly or by use of myocutaneous flaps after irrigation and debridement of wound. We describe a new treatment of poststernotomy wound infection by using the vacuum- assisted closure technique. This technique was successfully applied in 3 patients with poststernotomy wound infection and mediastinitis, and a healed sternotomy wound could be achieved using this new technique.
Debridement
;
Humans
;
Mediastinitis*
;
Myocutaneous Flap
;
Negative-Pressure Wound Therapy*
;
Sternotomy
;
Thoracic Surgery
;
Wound Infection*
;
Wounds and Injuries*
7.The Skin Irritations of Corrosive and Non-corrosive Irritants in Patients with Sensitive Skin.
Bo Hyun LEE ; Chang Keun PARK ; Hye One KIM ; Hee Jin JO ; Chun Wook PARK ; Cheol Heon LEE
Korean Journal of Dermatology 2007;45(6):551-559
BACKGROUND: Sensitive skin is largely agreed to be a lay term used by individuals who have reduced tolerance to frequent or prolonged use of cosmetics and toiletries, with symptoms ranging from subjective neurosensory forms of discomfort such as stinging, burning, itching, tightness and smarting sensations to visible signs of irritation such as erythema and scaling. Although the concept of sensitive skin is intriguing to many dermatologists, the diagnosis is dependant on self-perceived symptoms. Models to define sensitive skin are not standardized, and the term sensitive skin can be misleading. OBJECTIVE: The purpose of this study was to evaluate difference of influence to skin barrier function between corrosive and non-corrosive agents in sensitive skin. METHODS: 0.1%, 0.25%, 0.5%, 2% solution of sodium lauryl sulfate (SLS) and 1%, 2.5%, 5%, 20% solution of nonanoic acid (NAA) were applied on volar forearm skin for 24 hours in healthy controls and self-perceived sensitive skin subjects without underlying problems. Clinical score, transepidermal water loss (TEWL), and erythema-index (E-index) were compared between healthy controls and the sensitive skin group. RESULTS: Clinical scores, TEWL values and E-indices showed a rising curve concentration for each irritant in a similar pattern. There were no significant differences in clinical score and TEWL value between non-sensitive and sensitive skin. In contrast, E-indices evaluated from sensitive skin subjects were much higher than those in a healthy controls. CONCLUSION: An elevated TEWL value indicates barrier impairment. An increase in the erythema parameter shows that cutaneous vascular reactions have an unspecifically exaggerated reaction to various irritants and this induces multifarious inflammatory reactions and vasodilation. Therefore, the results of this study suggest that sensitive skin without underlying disease is derived from cutaneous vascular hyperreactivity and various inflammatory reactions, rather than barrier impairment.
Bites and Stings
;
Burns
;
Diagnosis
;
Erythema
;
Forearm
;
Humans
;
Irritants*
;
Pruritus
;
Sensation
;
Skin*
;
Sodium Dodecyl Sulfate
;
Vasodilation
8.Recurrent Rhabdomyolysis after Cerivastatin-Gemfibrozil Combination Therapy.
Hyun Su KIM ; Chang Wook JEONG ; Jo SUNG ; Sung Rok KIM ; Yun Ki KIM
Korean Journal of Nephrology 2002;21(2):322-326
A 64-year-old woman with ischemic heart disease was admitted to our hospital because of both leg pain and difficulty to walk for 5 days. She had taken cerivastatin and gemfibrozil for atherosclerosis and ischemic heart disease. One year ago, she had been admitted to our hospital because of acute renal failure due to rhabdomyolysis of unknown origin and was improved after conservative therapy. Laboratory studies revealed serum creatinine 1.2 mg/dL, creatine kinase 23,700 IU/L, serum myoglobin >500 ng/mL, urine myoglobin >3,000 ng/mL. (99m)Tc-HDP whole body Bone scan showed multiple increased uptakes of the soft tissue, especially both calf. With supportive care, she was recovered and discharged with normal creatinine(0.8 mg/dL) and creatine kinase(260 IU/L).
Acute Kidney Injury
;
Atherosclerosis
;
Creatine
;
Creatine Kinase
;
Creatinine
;
Female
;
Gemfibrozil
;
Humans
;
Leg
;
Middle Aged
;
Myocardial Ischemia
;
Myoglobin
;
Rhabdomyolysis*
9.Esophageal Obstruction Caused by the Solidification of Residue of an Enteral Feeding Formula.
Hancheol JO ; Ye Rim CHANG ; So Mi KIM ; Dong Wook KIM ; Ye Seob JEE
Journal of Clinical Nutrition 2018;10(1):25-30
The nutritional support of acutely ill patients is very important and early enteral nutrition is recommended. Feeding via the nasogastric route is used widely for its ease of access if the patient cannot maintain volitional food intake. If the position of the tip or side holes of the nasogastric tube (NGT) is above the gastroesophageal junction, there is the possibility of retention and solidification of the administered enteral feeding formula in the esophagus. Therefore, the tip of the NGT should be checked carefully; a chest radiograph to confirm its position can be considered, especially in patients with a higher risk of aspiration and gastroesophageal reflux. In addition, careful consideration of the risk factors that can trigger esophageal obstruction is required when feeding patients in the intensive care unit. This paper describes two unusual cases of esophageal obstruction caused by the solidification of residue of an enteral feeding formula.
Eating
;
Enteral Nutrition*
;
Esophagogastric Junction
;
Esophagus
;
Gastroesophageal Reflux
;
Humans
;
Intensive Care Units
;
Nutritional Support
;
Radiography, Thoracic
;
Risk Factors
10.Characterization of Xylanase of Cladosporium cladosporioides H1 Isolated from Janggyeong Panjeon in Haeinsa Temple.
Jin Young HONG ; Young Hee KIM ; Mi Hwa JUNG ; Chang Wook JO ; Jung Eun CHOI
Mycobiology 2011;39(4):306-309
Cladosporium cladosporioides H1 was found to be the most abundant microbe in Janggyeong Panjeon. C. cladosporioides H1 produced a 20 kDa xylanase, which was generally stable below 60degrees C and had specialized activity in an acidic condition. Our results may lead to the development of a strategy for preservation of organic cultural heritage environments.
Cladosporium