1.Surgical treatment of the anterior skull base tumor.
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(5):1018-1025
No abstract available.
Skull Base*
;
Skull*
2.Preperative evaluation of the mandible in patients with carcinoma of the oral cavity and tonsils.
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(5):972-976
No abstract available.
Humans
;
Mandible*
;
Mouth*
;
Palatine Tonsil*
3.Antibiotic loaded Plaster of Paris as a Prevention of Experimental Osteomyelitis in Rats
Chang Ju LEE ; Won Ho CHO ; Sung Kee CHANG ; Ho Guen CHANG ; Jae Hong KIM
The Journal of the Korean Orthopaedic Association 1989;24(5):1479-1485
Plaster of Paris is an effective ancillary treatment in the surgery of infected cavities in bone. It is well tolerated and spontaneously absorbed over the period of weeks to months, being replaced by bone of normal architecture. When the antibiotics incorporated into plaster of Paris, the antibiotics are capable of prolonged local release in bactericidal concentrations. Therefore it is proposed that antibiotics loaded plaster of Paris might be a simple adjuvant technique after good surgical debridement for the treatment of bone infection. The authors carried out an experiment to study the effect of plaster of Paris containing antibiotics for a prevention of experimental osteomyelitis, using 45 rats, which were divided into 3 groups. In the Group 1, a defect was made at the proximal metaphysis of the tibia, inoculated by Staphylococcus aureus sensitive to Cephradine and Tobramycin and then filled with plaster of Paris pellet. In the Group 2, a defect was filled with Cephradine loaded plaster of Paris pellet. In the Group 3, a defect was filled with Tobramycin loaded plaster of Paris pellet. Then we observed the healing process of the bone defect in the point of view of the gross findings, radiologic findings and histologic findings at 4th, 8th and 12th week after operation. The results of this study were as follows:l. In the control Group;all 30 cases were infected. 2. In the Group 2;only 4 of 30 cases were infected. 3. In the Group 3;all 30 cases were not infected. 4. The plaster of Paris filled into the defect was absorbed continuously and stimulated the new bone formation.
Animals
;
Anti-Bacterial Agents
;
Calcium Sulfate
;
Cephradine
;
Debridement
;
Osteogenesis
;
Osteomyelitis
;
Rats
;
Staphylococcus aureus
;
Tibia
;
Tobramycin
4.Bullous Necrotizing Vasculitis of the Skin.
Pyung Won PARK ; Chang Woo LEE ; Jae Hong KIM
Annals of Dermatology 1993;5(2):113-116
Three cases of necrotizing vasculitis clinically showing bullous skin lesions and histopathologically confirmed as leukocytoclastic vasculitis are reported. Compared with those of skin -limited non-bullous forms of cutaneous vasculitis, these cases showed relatively frequent abnormalities in urinalysis and required more aggresive corticosteriod therapy. Clinicians should be aware of the possible systemic involvements when the skin lesions are bullous in cutaneous necrotizing vasculitis.
Skin*
;
Urinalysis
;
Vasculitis*
5.Intralesional Recombinant Alpha-2a Interferon for the Treatment of Patients With Verruca.
Seung Won AHN ; Seong Joon SEO ; Chang Kwun HONG
Annals of Dermatology 2000;12(3):155-159
BACKGROUND: Interferon alpha-2a has already been shown to be effective in clinical use of virus-originated diseases such as hairy cell leukemia, condyloma acuminatum, and AIDS-related Kaposi's sarcoma. The use of recombinant alpha-interferon may allow common warts to be treated relatively atraumatically and with less incidence of recurrence. OBJECTIVE: We tried to determine the safety and effectiveness of intralesional injections of recombinant alpha-2a interferon in the treatment of patients with common warts. METHODS: A single wart on each patient was weekly injected with 0.75 to 1.5×10(5) IU/25mm2 of interferon for 8 weeks, and the response to treatment was followed up-to 6 months. RESULTS: Clearing of the treated wart at the end of treatment occurred in 5(71%) out of 7 patients and the rest showed no improvement. With evaluation for relapses up-to 6 months after treatment, warts relapsed in 2(40%) out of 5 patients. Therefore, 3(43%) out of 7 patients were completely free of warts 6 months after treatment. CONCLUSION: Intralesional recombinant interferon alpha-2a has a limited therapeutic effect, but may be considered as a therapeutic modality of recalcitrant verruca or when it can be anticipated that destructive techniques or blistering agents will not be tolerated.
Blister
;
Humans
;
Incidence
;
Injections, Intralesional
;
Interferon-alpha
;
Interferons*
;
Leukemia, Hairy Cell
;
Recurrence
;
Sarcoma, Kaposi
;
Warts*
6.Relationship between recurrence and histopathological and immunohistochemical pattern of layngeal papilloma.
Mi Sook CHANG ; Won Pyo HONG ; Kwang Moon KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(6):1280-1293
No abstract available.
Papilloma*
;
Recurrence*
7.Avulsion of the Tibial Attachment of the Posterior Cruciate Ligament of the Knee Joint (Seven Cases Report)
Sang Won PARK ; Chang Yong HUR ; Hong Keun LEE
The Journal of the Korean Orthopaedic Association 1988;23(6):1522-1528
The posterior cruciate ligament plays as basic stabilizer of the knee. Therefore the knee becomes unstable when tibial insertion of the posterior cruciate ligament is avulsed. The diagnosis may be delsyed or missed because of surgeon's 1sck of awareness or rare condition. The authors treated seven cases of avulsion fracture of posterior cruciate ligsment at the tibial attachment ares ranged from ten to thirty-two years. There were five male and two female. The results were as follows : 1. The cause of all seven cases injury was traffic accident. 2. The physical findings were seven positive posterior drawer test, seven cases of abrasion or laceration over the anterior proximal tibial surface and antero-medial surfsce of the knee joint. 3. The associated injury was comminuted fracture of the tibia and femur (1 case), rupture of collateral ligsment and comminuted fracture of the tibia (1 case) and zygomatic fracture (1 case). 4. The treatment methods were four cancellous fixation, one K-wire fixation after epiphyseal plate fusion but each one pull out wire and dexon suture before epiphyseal plate fusion. 5. The motion of knee joint was within normal limit and no instsbility was inspected at the three months after reduction.
Accidents, Traffic
;
Diagnosis
;
Female
;
Femur
;
Fractures, Comminuted
;
Growth Plate
;
Humans
;
Knee Joint
;
Knee
;
Lacerations
;
Male
;
Posterior Cruciate Ligament
;
Rupture
;
Sutures
;
Tibia
;
Zygomatic Fractures
8.Comparative Study on Quantitation of Left to Right Shunts in Ventricular Septal Defect Using Oximetry and Radionuclide Method.
Chang Yee HONG ; Jung Yun CHOI ; Se Won PARK ; Yong Soo YUN ; Chang Soon KOH
Journal of the Korean Pediatric Society 1985;28(4):340-344
No abstract available.
Heart Septal Defects, Ventricular*
;
Oximetry*
9.The proportional Changes of Tear Proteins in the Dry Eye Patients.
Serk Won HONG ; Han Ki CHANG ; Chang Hyun RHIM
Journal of the Korean Ophthalmological Society 1998;39(8):1627-1632
It is well studied about the composition of tear and it`s function, but not about the proportion of tear proteins in the dry eye, in which tear volume is reduced and tear film is unstable. Therefore, we performed this study to determine the proportion of tear proteins. This study involved 150 subjects, 50 volunteers and 100 outpatients who visited Ophthalmologic department from January to December in 1997. Dry eye was classified into mild and severe dry eyes. Four fractions of tear protein were demonstrated by electrophoresis. The proportion of tear proteins in fraction 1 to 4 were 31.0+/-5.9%(mean+/-standard deviation), 2.9+/-1.3%, 40.8+/-5.5%, 25.2+/-5.2%, in control group, 33.4+/-7.1%, 3.4+/-3.0%, 41.6+/-7.7%, 21.5+/-4.8% in mild dry eye group, 37.5+/-11.4%, 3.2+/-2.2%, 40.3+/-9.1%, 19.5+/-5.3% in severe dry eye group respectively. With severty of the dry eye, the proportion of fraction 1 was increased and the proportion of fraction 4 was decreased, both of which were statistically significant difference(P<0.01). In proportion to the severity of dry eye, the proportion of tear proteins became unstable. For the diagnosis and management of the dry eye,we consider the supplement of the decreased portion of tear proteins.
Diagnosis
;
Electrophoresis
;
Humans
;
Outpatients
;
Tears*
;
Volunteers
10.Antigen analysis of rickettsia typhi isolated in Korea: SDS-PAGE and immunoblotting characters.
Min Kee CHO ; Chang Soon YOON ; Yoon Won KIM ; Hee Sook KIM ; Chang Hong MIN
Journal of the Korean Society for Microbiology 1992;27(5):427-434
No abstract available.
Electrophoresis, Polyacrylamide Gel*
;
Immunoblotting*
;
Korea*
;
Rickettsia typhi*
;
Rickettsia*