Castleman disease is a relatively rare disease of differential diagnostic interest in patients with lymphadenophathy. The etiology and pathogenesis of the Castleman disease are still not elucidated and the MRI findings of disease has not yet been reported. Two patients with Castleman disease studied by MRI are presented: one case presented with a localized anterior mediastinal mass and the other case, with a neck mass. The lesions were characterized by relatively high signal intensities on both T1 and T2 weighted images in both cases, and significant degree of enhancement was seen in the cervical Castleman disease.
Giant Lymph Node Hyperplasia* ; Humans ; Lymph Nodes* ; Magnetic Resonance Imaging* ; Neck ; Rare Diseases

Total of 311 cases who were admitted to pediatric departmenr of Kyung Hee University Hospital from October, 1971 to December, 1975 were studied clinically about the cases in various age group. The results are as follows. 1) Convulsion was most frequent in children between 6months and 3years (38%), but it was least frequent in children from 10years to 15 years (7%). 2) The most common cause of convulsions in children was febrile convulsion(30.5%). 3) Tetanus (50.9%) was most frequent cause of convulsion in the neonatal period. 4) Febtile convulsion was most common in infants from one month to six months. 5) The most common cause of conculsions in infants from six months to three years was febrile convulsion (47.8%). 6) In children more than three years of age, idiopathic epilepsy was most frequent cause of convulsion (3 to 10 years and 10 years to 15years , 36%, 72.7% respectively).
Child* ; Epilepsy ; Humans ; Infant ; Seizures* ; Seizures, Febrile ; Tetanus

There have been few reports on fibrous dyplasia associated with secondary hyperparathyroidism. We report a case of a hemodialysis patient with secondary hyperparathyroidism concomitant with fibrous dysplasia of the jaws causing an abnormal facial deformity.
Congenital Abnormalities ; Humans ; Hyperparathyroidism, Secondary* ; Jaw* ; Renal Dialysis

A 14-month-old child visited emergency room with stuporous mental state. He had been suffering from failure to thrive (FTT) and emaciation since three months of age, but he had good appetite and had been euphoric. A large mass was found in the third ventricle by brain CT and MRI. His parents refused operative removal of the mass and he expired 14 days after admission. It is necessary to include diencephalic syndrome in the differential diagnosis of failure to thrive when infants show FTT despite of good appetite and euphoric status.
Appetite ; Brain ; Brain Neoplasms ; Child ; Diagnosis, Differential ; Emaciation ; Emergency Service, Hospital ; Failure to Thrive* ; Humans ; Infant ; Magnetic Resonance Imaging ; Parents ; Stupor ; Third Ventricle

PURPOSE: To investigate the in vivo proton MRS features of various focal hepatic lesions and to distinguish these features according to the involved. MATERIALS AND METHODS: Twenty-five hepatic lesions [hepatocellular carcinoma (n=7), cholangiocarcinoma(n=3), metastatic tumor (n=9), hemangioma (n=3), hepatic abscess (n=2), lymphoma (n=1)] underwent proton MR spectroscopy using a 1.5T unit and a localized proton STEAM sequence, without respiratory interruption, The findings of this in-vivo sequence were then reviewed, with particular attention to the presence and location of dominant peaks. RESULTS: In-vivo proton MR spectra were successfully acquired in all cases. A dominant lipid peak appeared in the MR spectra of the hepatocellular carcinomas, metastatic tumors, hepatic abscesses, lymphoma, one hemangioma and one cholangiocarcinoma(88%) at 1.3ppm, but not in two cholangiocarcinomas and one hemangioma. The spectral peaks of other metabolites appeared very irregular and even different in the same disease. CONCLUSION: In focal hepatic lesions, the spectra obtained during in-vivo proton MRS were useful, and a lipid peak was most frequent and dominant. Among the various neoplasms there were, however, no specific MR spectral features, and nor did such features vary according to the specific pathologic entity.
Carcinoma, Hepatocellular ; Cholangiocarcinoma ; Hemangioma ; Liver Abscess ; Lymphoma ; Magnetic Resonance Spectroscopy ; Protons* ; Steam

The incidence of anencephaly ranges from 0.1 to 6.7 per 1,000 births. Female fetuses predominated, especially among prematures, with a ratio of between 3 and 7 to 1. The infants are either stillborn or die within a few days of birth. By about 23 days?gestational age the neural tube is complete, except for an opening at each end, the anterior and posterior neuropores. Failure of closure of the anterior neuropore causes anencephaly. Ultrasound scanning of the skull in the anencephalic fetus, measurement of alpha-fetoprtein countent in amniotic fluid may also ve of help in rntrauterine diagnosis. Four cases of anencephaly with mutiple anomalies experienced at nursery of Kyung Hee University Hospital were reported with brief review of related literaures.
Amniotic Fluid ; Anencephaly* ; Diagnosis ; Female ; Fetus ; Humans ; Incidence ; Infant ; Neural Tube ; Nurseries ; Parturition ; Skull ; Ultrasonography

Hepatic angiomyolipoma is a rare benign lipomatous tumor of the liver. Radiologic studies usually reveal a fat component, but since this may be minimal, such a component is not always detected. We report a case of atypical hepatic angiomyolipoma which because of the non-visualization of fat at CT and MR imaging, was difficult to differentiate from other hypervascular tumors.
Angiomyolipoma* ; Liver ; Liver Neoplasms ; Magnetic Resonance Imaging

OBJECTIVE: To explore the in-vivo 1H- MR spectral features of adnexal lesions and to characterize the spectral patterns of various pathologic entities. MATERIALS AND METHODS: Thirty-one patients with surgically and histopathologically confirmed adnexal lesions underwent short echo-time STEAM (stimulated echo acquisition method) 1H- MR spectroscopy, and the results obtained were analysed. RESULTS: The methylene present in fatty acid chains gave rise to a lipid peak of 1.3 ppm in the 1H- MR spectra of most malignant tumors and benign teratomas. This same peak was not observed, however, in the spectra of benign ovarian epithelial tumors: in a number of these, a peak of 5.2 ppm, due to the presence of the olefine group (-CH=CH-) was noted. The ratios of lipid peak at 1.3 ppm to water peak (lipid/water ratios) varied between disease groups, and in some benign teratomas was characteristically high. CONCLUSION: An intense lipid peak at 1.3 ppm is observed in malignant ovarian tumors but not in benign epithelial tumors. 1H- MRS may therefore be helpful in the differential diagnosis of adnexal lesions.
Adnexal Diseases/*diagnosis ; Adult ; Aged ; Cystadenoma, Mucinous/diagnosis ; Diagnosis, Differential ; Female ; Human ; Magnetic Resonance Spectroscopy/*diagnostic use ; Middle Age ; Ovarian Neoplasms/diagnosis ; Protons ; Support, Non-U.S. Gov't ; Teratoma/diagnosis ; Uterine Neoplasms/diagnosis

We report a case of acute pancreatitis secondary to pancreatic neuroendocrine tumor. A 46-year old man presented with upper abdominal pain. The serum amylase and lipase were elevated. Abdominal computed tomography (CT) and magnetic resonance cholangiopancreatography revealed a 1.7 cm sized mass at the pancreas body with a dilatation of the upstream pancreatic duct and mild infiltrations of peripancreatic fat. An endoscopic ultrasound-guided fine needle biopsy was performed for the pancreatic mass, but only necrotic tissue was observed on the pathologic examination. A chest and neck CT scan revealed anterior mediastinal, paratracheal, and cervical lymph node enlargement, which were indicative of metastasis. An ultrasound-guided core needle biopsy was performed for the enlarged neck lymph node, and pathologic examination revealed a metastatic poorly differentiated carcinoma. Immunohistochemical analysis showed positive staining for synaptophysin, chromogranin A, and CD 56, indicative of a neuroendocrine carcinoma.
Abdominal Pain ; Amylases ; Biopsy, Fine-Needle ; Biopsy, Large-Core Needle ; Carcinoma, Neuroendocrine ; Cholangiopancreatography, Magnetic Resonance ; Chromogranin A ; Dilatation ; Endoscopic Ultrasound-Guided Fine Needle Aspiration ; Lipase ; Lymph Nodes ; Neck ; Neoplasm Metastasis ; Neuroendocrine Tumors ; Pancreas ; Pancreatic Ducts ; Pancreatitis ; Synaptophysin ; Thorax ; Tomography, X-Ray Computed

OBJECTIVES: The objective of this study was to investigate the relationship between coronary artery calcification and risk factors of cardiovascular disease with multidetector computed tomography. METHODS: Data were collected from 5,899 males between 30 and 59 years old by interview, survey, physical examination, blood test, and multidetector computed tomography in the university hospital from January 2010 to December 2011. We confirmed the coronary artery calcium scores of subjects by multidetector computed tomography and identified risk factors of cardiovascular disorders. We investigated the relationship between coronary artery calcification and risk factors of cardiovascular disorders. RESULTS: Mean calcium score of the coronary arteries in 5,899 participants was 8.20, and 773 participants (13.1%) exhibited coronary artery calcification. The presence of coronary artery calcification was correlated to risk factors of cardiovascular disease (age, blood pressure, triglyceride, HDL cholesterol, LDL cholesterol, glucose, Apolipoprotein A-1, Apolipoprotein B, body mass index, waist circumference) and risk assessment tools of cardiovascular disorders. Significant predicted factors of coronary artery calcification had different patterns in each age group (30-39, 40-49, 50-59 years old). CONCLUSIONS: We confirmed the relationship between coronary artery calcification and either typical risk factors of cardiovascular disease or risk assessment tools of cardiovascular disease. In addition, we also observed that the pattern of these factors varied according to age. Therefore, age-related variation needs to be considered in management strategies to prevent cardiovascular disease.