1.A case of seizure associated eHuEPO therapy for hemosiderosis on a chronic renal failure patient.
Kee Hyoung LEE ; Moon Jae KIM ; Chang Whan BAE
Korean Journal of Nephrology 1992;11(2):180-186
No abstract available.
Hemosiderosis*
;
Humans
;
Kidney Failure, Chronic*
;
Seizures*
4.Malignant Hyperthermia: A Case Report
Hak Weon CHANG ; Kwan Su PARK ; Chang Whan KIM ; Dong Seok NAM ; Hyo Sang PARK ; No Boo PARK ; Jong Bae KIM
Journal of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons 1997;19(1):109-114
Acidosis
;
Adult
;
Anesthesia
;
Anesthetics
;
Cyanosis
;
Dantrolene
;
Early Diagnosis
;
Humans
;
Incidence
;
Male
;
Malignant Hyperthermia
;
Muscle, Skeletal
;
Pentobarbital
;
Succinylcholine
;
Tachycardia
5.Percutaneous Gallbladder Drainage for Delayed Laparoscopic Cholecystectomy in Patients with Acute Cholecystitis.
Do Gyun KIM ; Chang Whan OH ; Kon Hong KIM ; Bae Geun PARK ; Woo Gil KIM
Korean Journal of Hepato-Biliary-Pancreatic Surgery 2001;5(1):103-108
BACKGROUND/AIMS: It have been reported that operative mortality and morbidity rate rise significantly when emergency cholecystectomy is performed in critically ill patients with acute cholecystitis(AC), and many studies have also concluded that delayed or interval laparoscopic cholecystectomy(LC) in patients with AC demonstrated high conversion rate and complication rate compared with early LC. However, if the acutely inflamed gallbladder(GB) is decompressed by emergent percutaneous gallbladder drainage(PGBD), it may decrease the technical difficulty of LC allowing successful delayed LC or may decrease the wound complication of delayed open cholecystectomy, when the patient is in better condition. The purpose of this retrospective study was to assess the outcome of delayed cholecystectomy focused on LC following PGBD in patients with AC METHODS: A total of 181 patients with AC were divided into PGBD(n= 66) and non-PGBD group(n= 115), and each group were subdivided into PGBD-delayed LC(after 72 hours of admission, n= 32), PGBD-open cholecystectomy(n= 20), non-PGBD-early LC(within 72 hours of admission, n= 40), non- PGBD-delayed LC(n= 17), non PGBD-open cholecystectomy group(n= 58) and others. PGBD group had higher incidence of comorbidity compared with non-PGBD group. Outcomes of cholecystectomy was assessed by conversion rate and morbidity rate(chi2 test), LC time and hospital stay(median test) for LC, and morbidity for open cholecystectomy in PGBD group compared with those of non PGBD group. RESULTS: PGBD promptly relieved of symptom of AC in 94 % of patients and showed 3 % of technical failure and 4.5 % of complication rate. Compared with non PGBD-early and delayed LC group, the PGBD-delayed LC group showed longer LC time(median 110 min vs 82.5, p < 0.05, vs 95 min), a little lower conversion rate(12.5 % vs 22.5 % vs 17.6 %), similar morbidity rate(19% vs 17.5 % vs 29 %) and prolonged total hospital stay(median 12.5 days vs 7 days, p < 0.001, vs 10 days). In open cholecystectomy series, PGBD group showed lower morbidity rate compared with non PGBD group(5% vs 24 %, p < 0.05) CONCLUSION: Unlike to open cholecystectomy series, PGBD did not significantly improve the outcome of LC for AC as assessed by conversion and morbidity rate and hospital stay compared with non PGBD. Thus we can conclude that although PGBD is a safe and effective emergency procedure for AC, it should be limited to higher risk group such as elderly or critically ill patients and to acalculous cholecystitis.
Acalculous Cholecystitis
;
Aged
;
Cholecystectomy
;
Cholecystectomy, Laparoscopic*
;
Cholecystitis, Acute*
;
Comorbidity
;
Critical Illness
;
Drainage*
;
Emergencies
;
Gallbladder*
;
Humans
;
Incidence
;
Length of Stay
;
Mortality
;
Retrospective Studies
;
Wounds and Injuries
6.Posterior Fossa Decompression for Hypertensive Cerebellar Encephalopathy: Case Report.
Moon Sool YANG ; Jae Whan LEE ; Yong Bae KIM ; Tae Seung KIM ; Kyu Chang LEE
Korean Journal of Cerebrovascular Surgery 2004;6(1):73-76
Hypertensive encephalopathy is a medical emergency that is usually presented with manifestating headache, nausea, and visual disturbance. The disease predominantly involves the parieto-occipital white matter. Although cerebellar lesion accompanying hydrocephalus has been occasionally described in the literature, medical management has been sufficient for relieving the posterior fossa hypertension. In the present case, we report a patient who was diagnosed with primary hypertensive cerebellar encephalopathy refractory to medical management and who was successfully treated by surgical decompression of the posterior fossa. A pathologic microscopic inspection of the tissue specimen confirmed hypertensive vascular change.
Decompression*
;
Decompression, Surgical
;
Emergencies
;
Headache
;
Humans
;
Hydrocephalus
;
Hypertension
;
Hypertensive Encephalopathy
;
Nausea
7.Effect of Peritoneal Fluid with Endometriosis on Mouse Embryo Development in vitro.
Byeong Jun JUNG ; Yeon Jung YUN ; Hyun Jung CHANG ; Sang Hoon LEE ; Do Whan BAE ; Min HUR
Korean Journal of Obstetrics and Gynecology 1997;40(4):784-792
Endometriosis affects up to 5 million women in the united states. The number of cases observed at any time is 1 in 15(7%) women in the reproductive age range. Infertility occurs in as many as 30% to 40% of cases. Anatomical compromise with failure of oocyte capture and transport is an eviednt explanation for infertility in women suffering from advanced(stageIII/IV) endometriosis. In contrast, the pathophysiology in couples suffening from mild to moderate endometriosis as a sole infertility diagnosis is poorly understood. Research over the last decade indicates that women with endometriosis suffer from excessive activstion of immunocompetent cells within the pelvis. In experimental paradigms, adversd effects of a peritoneal fluid on the reproductive process of the endometriosis patients can be demonstrated and include:(1) Phagocytosis of sperm(2) Decreased sperm motility(3) Alteration of sperm-egg interactions(4) Failure of oocytes capture by the fimbria and(5) Impeded embryo development. These data raise the possibility that the intraperitoneal inflammatory process observed in women with endometriosis may be responsible for the associated infertility. The purpose of this study was to evaluate the effect of peritoneal fluid(PF) from patient with moderate endometriosis on mouse embryo development.PF was aspirated from the posterior cul-de-sac at laparoscopy and centrifuged, and the cell-free superantant was not heat-inactivated and not filtered. Fifty percent PF in human tubular fluid(HTF) media was prepared as a study group. The control group consisted of PF with a nonendometriosis and of 0.5% bovine serum albumin and HTF. The in vitro fertilization was performed with these culture media. We were observed distribution of embryo under the microscopy at 24 hours, 72 hours, 92 hours and 120 hours after insemination. The 2-cell embryonic stages in the study group(254 ovums) and those in the control group(247 ovums) at 24 hours were 50.4%, 70.4%, respectively. At 72 hours, the embryonic stages of both groups were reached the morula stage. At 72 hours, only 7.0% of the embryos in the study group reached the hatching, versus 55.7% in the control group. (p < 0.001). At the 120 hours, 100% of embryos in study group were degenerating, versus only 13.2% in the control group. As a result, the peritoneal fluid of the endometriosis patients exert an adverse influence on early reproductive performance, especially inhibiting embryo development. The peritoneal fluid may be as a mediator in the pathogenesis of endometriosis associated subfertility.
Animals
;
Ascitic Fluid*
;
Culture Media
;
Diagnosis
;
Embryonic Development*
;
Embryonic Structures*
;
Endometriosis*
;
Family Characteristics
;
Female
;
Fertilization in Vitro
;
Humans
;
Infertility
;
Insemination
;
Laparoscopy
;
Mice*
;
Microscopy
;
Morula
;
Oocytes
;
Pelvis
;
Phagocytosis
;
Pregnancy
;
Serum Albumin, Bovine
;
Spermatozoa
;
United States
8.Effect of Peritoneal Fluid with Endometriosis on Mouse Embryo Development in vitro.
Byeong Jun JUNG ; Yeon Jung YUN ; Hyun Jung CHANG ; Sang Hoon LEE ; Do Whan BAE ; Min HUR
Korean Journal of Obstetrics and Gynecology 1997;40(4):784-792
Endometriosis affects up to 5 million women in the united states. The number of cases observed at any time is 1 in 15(7%) women in the reproductive age range. Infertility occurs in as many as 30% to 40% of cases. Anatomical compromise with failure of oocyte capture and transport is an eviednt explanation for infertility in women suffering from advanced(stageIII/IV) endometriosis. In contrast, the pathophysiology in couples suffening from mild to moderate endometriosis as a sole infertility diagnosis is poorly understood. Research over the last decade indicates that women with endometriosis suffer from excessive activstion of immunocompetent cells within the pelvis. In experimental paradigms, adversd effects of a peritoneal fluid on the reproductive process of the endometriosis patients can be demonstrated and include:(1) Phagocytosis of sperm(2) Decreased sperm motility(3) Alteration of sperm-egg interactions(4) Failure of oocytes capture by the fimbria and(5) Impeded embryo development. These data raise the possibility that the intraperitoneal inflammatory process observed in women with endometriosis may be responsible for the associated infertility. The purpose of this study was to evaluate the effect of peritoneal fluid(PF) from patient with moderate endometriosis on mouse embryo development.PF was aspirated from the posterior cul-de-sac at laparoscopy and centrifuged, and the cell-free superantant was not heat-inactivated and not filtered. Fifty percent PF in human tubular fluid(HTF) media was prepared as a study group. The control group consisted of PF with a nonendometriosis and of 0.5% bovine serum albumin and HTF. The in vitro fertilization was performed with these culture media. We were observed distribution of embryo under the microscopy at 24 hours, 72 hours, 92 hours and 120 hours after insemination. The 2-cell embryonic stages in the study group(254 ovums) and those in the control group(247 ovums) at 24 hours were 50.4%, 70.4%, respectively. At 72 hours, the embryonic stages of both groups were reached the morula stage. At 72 hours, only 7.0% of the embryos in the study group reached the hatching, versus 55.7% in the control group. (p < 0.001). At the 120 hours, 100% of embryos in study group were degenerating, versus only 13.2% in the control group. As a result, the peritoneal fluid of the endometriosis patients exert an adverse influence on early reproductive performance, especially inhibiting embryo development. The peritoneal fluid may be as a mediator in the pathogenesis of endometriosis associated subfertility.
Animals
;
Ascitic Fluid*
;
Culture Media
;
Diagnosis
;
Embryonic Development*
;
Embryonic Structures*
;
Endometriosis*
;
Family Characteristics
;
Female
;
Fertilization in Vitro
;
Humans
;
Infertility
;
Insemination
;
Laparoscopy
;
Mice*
;
Microscopy
;
Morula
;
Oocytes
;
Pelvis
;
Phagocytosis
;
Pregnancy
;
Serum Albumin, Bovine
;
Spermatozoa
;
United States
9.Unusual peripheral osteomas: Report of 2 cases.
Chang Ho SUH ; Doo Hee LEE ; Hyung Soon KIM ; Jung Soo BAE ; Hyun Ho JOO ; Dong Whan WEON ; Il Hyun KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2001;27(3):276-280
Osteoma is defined as a benign neoplasm of bony tissue. Osteomas are divided into two groups: central and peripheral by origin, compact and cancellous by histopathologic findings. Solitary osteoma of jaw bone, not related with Gardner syndrom, is relatively uncommon. We present two cases of huge solitary peripheral osteomas: compact type exophyting osteoma on the inferolingual side of mandibular angle and cancellous type on the residual ridge of posterior maxilla, which is extremely rare.
Jaw
;
Maxilla
;
Osteoma*
10.Signal Averaged Electrocardiography Using Holter Tape in Patients without Heart Disease.
Soon Chul BAE ; Seok Jun MOON ; Jae Goo KWON ; Duk Whan JANG ; Chang Won LEE ; Hong Soon LEE ; Soo Woong YOO ; Moo Yong RHEE ; Hak Choong LEE
Korean Circulation Journal 1997;27(1):42-48
BACKGROUND: Ventrlcular tachyarrhythmias are major cause of sudden cardiac death in patients after myocardial infarction and their accurate detection seems to be important in prevention of sudden cardiac death. Clinical findings, treasmill test, holter monitoring and coronary angiography have been used to search for high risk group in sudden cardiac death. Recently electrographysiologic stimulation has been to this, but it is not practical, because of high cost and invasiveness. Signal averaged electrocardiogram(SAECG) may be helpful in prediction of high risk group in sudden cardiac death. So we try to know the values of SAECG in Korean patients without heart disease. RESULTS: 1) The mean value and standard deviation of Time domain analysis is as follows ; fQRS : 106.8+/-12.3ms, RMS : 36.2+/-21.5(micro)V, LAS : 27.2+/-8.1ms. 2) The mean value and standard deviation of Spectral turbulence analysis is a follows ; LSCR : 58.6+/-3.9, ISCM : 95.2+/-0.8, ISCSD : 71.8+/-15.7, SE : 6.9+/-1.8. CONCLUSION: There was no significant difference between male and female. Time domain analysis shows significant differences among each hour but spectral turbulence analysis did not. Spectral turbulence analysis shows high specificity.
Coronary Angiography
;
Death, Sudden, Cardiac
;
Electrocardiography*
;
Electrocardiography, Ambulatory
;
Female
;
Heart Diseases*
;
Heart*
;
Humans
;
Male
;
Myocardial Infarction
;
Sensitivity and Specificity
;
Tachycardia