1.13-cis-Retinoic Acid Treatment of Steroid Acne.
Kyung Hee WHANG ; Chang Jo KOH ; Sung Nack LEE ; Chung Koo CHO
Korean Journal of Dermatology 1983;21(1):85-89
No abstract available.
Acne Vulgaris*
;
Isotretinoin*
2.The Clinical Study of Free Dorsalis Pedis Flap by Microsurgery
Kuhn Sung WHANG ; Kwang Suk LEE ; Kwang Hoe KIM ; Beung In CHANG
The Journal of the Korean Orthopaedic Association 1985;20(3):419-426
Free dorsalis pedis flap transfers were performed in twelve cases at the Department of Orthopaedic Surgery of Hanyang University Hospital from January, 1980 to December, 1983. The result were summerized as followings; 1. Among twelve cases of the free dorsalis pedis flap transfer, neurovascular flap transfers were performed in nine cases and tendocutaneous flap transfers in five cases. 2. In all cases the textures of flaps were improved and the bulky subcutaneous fat tissues were shrunk gradually, so cosmetically good results were obtained. 3. Temperature, pain, protective and touch sensations were retained or restored by preservation of sensory nerve. 4. Free dorsalis pedis flap transfer has many advantages compared to conventional skin grafts, such as shorter therapeutic time, lesser physical or economic demands and primary covering to vital organ. 5. In injured hands, the application of free dorsalis pedis flap transfer including long extensor tendons of foot has been shown the excellent clinical result in the point of functional and cosmetic effect in dorsum of hand, as transferring simultaneously free tendon and skin flap. 6. Free dolis pedis flap transfer needs abundant experiences, meticulous microvascular technique and anatomic knowledge.
Clinical Study
;
Foot
;
Hand
;
Microsurgery
;
Sensation
;
Skin
;
Subcutaneous Fat
;
Tendons
;
Transplants
3.Heat Production and Thermal Necrosis by Cortical Drilling.
Kuhn Sung WHANG ; Hyun Kee CHUNG ; Choong Hyeok CHOI ; Jong Heon KIM ; Chang Woo HAN ; Doo Jin PAIK
Journal of Korean Orthopaedic Research Society 1999;2(2):164-170
PURPOSE: The present study was performed to determine the optimum conditions(RPM, load, sharpness of drill) for drilling human cortical bone with standard drill, and to evaluate the histological changes occuring in bone after drilling. MATERIALS AND METHODS: in experiment I, we measured temperature elevations and the durations of temperature elevation in cadaveric femoral cortices at specific distances from the drill hole wall while drilling. The effects of drilling force, speed and new versus worn drill on the termperature were determined. In experiment II, we also measured temperature elevations in the same manner in porcine femoral cortices and evaluated the histological changes occuring in bone after drilling. RESULTS: In experiment I, the most significant temperature elevation(68.4degrees C ) was found when worn drill was used. The lower drilling force and faster speed resulted in 55.1degrees C and 45.8degrees C temperature elevation, respectively. However, drill diameter was not a significant factor for temperature elevation. In experiment II, greater heat production was measured with worn drill, at lower drilling forces, at faster drill speed. The acute histologic reactions in bone were hyperemia, degeneration of osteocytes, change in bone stainability, tears, and fragmentation of the bone edges around the drill holes. The observed histological changes were proportional to the amount of trauma produced, that is, the greater the degree of thermal irritation, the greater the degree of histologic activity. CONCLUSION: In cortical drilling, greater heat production was measured with worn drill, at lower drilling forces, at faster drill speed and the greater the degree of thermal irritation, the greater the degree of histologic activity. A further study of the reaction of bone to drilling at longer intervals of time at different conditions may possibly show whether aseptic thermal necrosis could be prevented.
Cadaver
;
Hot Temperature*
;
Humans
;
Hyperemia
;
Necrosis*
;
Osteocytes
;
Thermogenesis*
4.The Influence of Labor and Cesarean Section in Uroflowmetry.
Youn Seok CHOI ; Soon Gu WHANG ; Chang Kyu HUH ; Chang Youn KIM ; Tae Sung LEE ; Duk Yoon KIM
Korean Journal of Obstetrics and Gynecology 2003;46(9):1674-1679
OBJECTIVE: The purpose of this study is to evaluate the uroflow parameters of the pregnant women before delivery and immediate postpartum period. METHODS: Forty four patients delivered by spontaneous vaginal delivery (NVD group) and 46 patients by Cesarean section (C/SEC group) and 28 non-pregnant young women (Control group) were included in this study. Uroflow were checked 1 day before and 2 days after delivery by Jupiter 8000 (FM Wiest(R)) uroflowmetry. Mean value of the uroflow parameters in each group was compared using ANOVA t-test. For continuous data, linear associations with each of the uroflow parameters were assessed using a Pearson correlation coefficient. RESULTS: Maximal (18.48+/-5.21 mL/sec) and mean flow rate (9.45+/-3.73 mL/sec) of pregnant women were lower than control group (22.75+/-5.14 mL/sec), and were not changed after delivery (18.79+/-6.03 mL/ sec). Total flow time of pregnant woman (14.06+/-6.09 sec) was longer than control group (8.05+/-5.32 sec) before delivery, and increased after delivery especially after cesarean delivery. Time to peak flow of pregnant women (8.44+/-9.48 sec) was shorter than control group (16.33+/-6.11 sec) before delivery, and was similar to control group after delivery. Total voided volume (121.39+/-50.17 mL) was less than control group before delivery, and was increased after delivery (246.77+/-127.42 mL). Total voided volume after delivery was not different with control group statistically. CONCLUSION: There was no statistically differences before and after delivery in maximal flow rate, but was lower than non-pregnant women. Total flow time was much prolonged after delivery, especially after cesarean delivery. Time to peak flow and voided volume were restored to levels of non-pregnant women after delivery.
Cesarean Section*
;
Female
;
Humans
;
Postpartum Period
;
Pregnancy
;
Pregnant Women
5.Combined Anterior and Posterior Approach in Operating on Complex Acetabular Fractures.
Weon Yoo KIM ; Jin Hyung SUNG ; Chang Hwan HAN ; Jin Sung CHEON ; Hee Ju WHANG
The Journal of the Korean Orthopaedic Association 2001;36(3):287-292
PURPOSE: To report the results of a combined anterior and posterior approach to complex acetabular fractures and establish the guidelines for the operative treatment of complex acetabular fractures. MATERIALS AND METHODS: Thirteen fractures (8 both column, 5 T-shaped fractures) of thirteen patients (8 men, 5 women) were treated with this combined anterior and posterior approach from August 1995 to December 1999. We reviewed the clinical and radiological results for an average of 33months (range, 12-60) follow-up. RESULTS: This approach resulted in an anatomical reduction in ten (78%) patients and, two imperfect and one poor reduction. The average Harris hip score was 69.2 (range, 58-87) and the clinical results were good in eleven, very good in one and poor in one patient using the D'Aubigne/Postel clinical grading. A poor reduction occurred in one patient who had a both column fracture that extended to the ipsilateral sacroiliac joint combined with a joint subluxation. CONCLUSION: Overall clinical results for most complex acetabular fractures treated by a combined anterior and posterior approach were preferable to other approaches, but we must consider an extensile or extended ilioinguinal approach to be an alternative surgical approach in this complicated fracture that involves the sacroiliac joint.
Acetabulum*
;
Follow-Up Studies
;
Hip
;
Humans
;
Joints
;
Male
;
Sacroiliac Joint
6.Clinical Analysis of the CNS Malignant Lymphomas.
Jae Sung AHN ; Chang Jin KIM ; Yang KWON ; Seung Chul RHIM ; Jung Kyo LEE ; Byung Duk KWUN ; Choong Jin WHANG
Journal of Korean Neurosurgical Society 1995;24(5):546-554
Malignant CNS lymphoma is a malignant intracranial tumor and in most cases they run a fulminating course if left untreated, with 3 to 5 months survival after appearance of the initial symptoms. Sixteen patients with malignant lymphoma were treated in Asan Medical Center from 1989 to 1994. All patients were underwent tissue diagnosis with subtotal resection or stereotactic biopsy and followed by cranial or craniospinal irradiation with or without systemic chemotherapy. One and three year survival rate of the patients was 88% and 78% respectively. In conclusion, addition of chemotherapy and/or cranial radiation for treatment of the CNS lymphoma may improve survival.
Biopsy
;
Chungcheongnam-do
;
Craniospinal Irradiation
;
Diagnosis
;
Drug Therapy
;
Humans
;
Lymphoma*
;
Survival Rate
7.A Case of Numb-Chin Syndrome Assoicated with Hodgkin's Disease.
Man Wook SEO ; Ji Sung KIM ; Kwang Seok KO ; Byung Cheol OH ; Yun Jeong YANG ; Chang Yeol IM ; Ho Kyeong WHANG
Journal of the Korean Neurological Association 2000;18(3):372-374
The numb chin syndrome (NCS) is characterized by chin or lower lip numbness restricted to the distribution of the mental nerve (the distal trigeminal nerve). The authors report a patient whose initial symptom of tumor recurrence was unilateral numbness of the chin. A 65-year-old male was admitted because of paresthesia around the left chin and left lower lip. Neurologic examination revealed hypesthesia on the left side of chin, lower lip and buccal mucous mem-brane. Bone scan (Tc-99m MDP) showed focal hot uptakes on the left mandible and left first rib. Brain CT with bone window setting showed a focal osteolytic lesion in the bone marrow of the left mandibular canal without destruction of bone cortex. Both coronal T1 weighted image and axial T2 weighted image showed focal low signal intensities on the left ramus. The pathophysiologic mechanism could be understood by identification of the pathologic focus.
Aged
;
Bone Marrow
;
Brain
;
Chin
;
Hodgkin Disease*
;
Humans
;
Hypesthesia
;
Lip
;
Male
;
Mandible
;
Neurologic Examination
;
Paresthesia
;
Recurrence
;
Ribs
8.The influence of helicobacter pylori on the development of gastric cancer.
Jin Ho LEE ; Su Yung JEON ; Hee Yong HAHM ; Jin Il YOON ; Sung Bo WHANG ; Woon Tae JEONG ; Won Chang SHIN ; Kwan Yop KIM
Korean Journal of Medicine 1993;45(2):187-193
No abstract available.
Helicobacter pylori*
;
Helicobacter*
;
Stomach Neoplasms*
9.Bullous Pilomatricoma: A Case Report.
Chang Yoon SIM ; Hyun Ju KIM ; A Young PARK ; Jong Suk LEE ; Kyu Uang WHANG ; Young Lip PARK ; Jung Eun KIM ; Hyun Ju LEE ; Sung Yul LEE
Korean Journal of Dermatology 2017;55(10):708-709
No abstract available.
Pilomatrixoma*
10.A Case of Hyperpigmented Mycosis Fungoides with CD8 Positive Cells.
Hyun Ju KIM ; Chang Yoon SHIM ; Sung Yul LEE ; Young Lip PARK ; Jong Suk LEE ; Kyu Uang WHANG
Korean Journal of Dermatology 2017;55(3):191-194
Mycosis fungoides (MF) represents the prototype of cutaneous T-cell lymphoma, which is defined as clonal expansion of skin-homing T lymphocytes. The natural history of MF is characterized by an indolent progression through patch, plaque, tumor, and visceral stages; however, this progression is not necessarily seen in all patients. Classically, the atypical lymphocytes in MF are CD3/CD4 positive with a loss of CD7. However, fewer than 5% of cases of MF present with a cytotoxic/suppressor CD8 positive phenotype, which presents with a variety of clinical features, including granulomatous, folliculotropic, poikilodermatous, hypopigmented, and hyperpigmented MF. Different immunophenotypic variants have been reported in MF but seem to lack any specific behavior and prognosis. Herein, we report a rare case of hyperpigmented MF with CD8 positive cells.
Humans
;
Hyperpigmentation
;
Lymphocytes
;
Lymphoma, T-Cell, Cutaneous
;
Mycosis Fungoides*
;
Natural History
;
Phenotype
;
Prognosis
;
T-Lymphocytes