It has long been an accepted policy to employ radiation therapy as initial treatement of choice for most casesof invasive carcinoma of cervix uteri. But, complications following radiotherapy were troublesome problem fot thepatients cured by radiation therapy. The aim of the present study is to present the types and rate of complicationsand to evalute the contributing facors induced the radiation complications. The aim of the present study is topresent the types and rate of complications and to evalute the contributing factors induced the radiationcomplications. 957 cases of invasive carcinoma of cervix uteri receiving radiation therapy were analyzed. Theconclusions are as follows; 1. Bowel complications developed in 96 cases (10.03%). 2. 86% of all bowelcomplications appeared during the first 18 months and most frequently seen after 6 to 12 months(40.03%). 3. Thefrequency of complicaiton was higher in older age and larger irradiation dose, but there is no apparentcorrelation between stage and the occurrence of complications. 4. Portal combination was also a contributingfactor. Highest frequency was noted in AP & PA parallel opposing portals followed by 4 oblique portals and boxtechnique.
Cervix Uteri ; Female ; Radiotherapy

No abstract available.
Epidemiology*

No abstract available.
Blood Platelets* ; Fetal Growth Retardation* ; Platelet Count* ; Pregnancy*

Plain radrographs of thirty nine patients with giant cell tumor of long bone and CT scans of twenty patients among the thirty patients were reviewed retrospectively to evaluate the frequency and significance of sclerosis of the tumor margin. The sclerosis of the tumor margin was observed on plain radiographs in thirteen patients(33.3%) and they were located either on epiphyseal or on both epiphyseal or metaphyseal portion of the tumor. The authors concluded that the giant cell tumor should not be excluded from the differential entities eventhough the tumor has the marginal sclerosis.
Diagnosis, Differential* ; Giant Cell Tumors* ; Giant Cells* ; Humans ; Retrospective Studies ; Sclerosis* ; Tomography, X-Ray Computed

Now that ankylosing spondylitis is known to be relatively common, it is important that mild cases should be diagnosed earlier to avoid inappropriate investigation and unhelpful non-specific therapy and to improve social rehabilitation. However, difficulties in the diagnosis of ankylosing spondylitis are often encountered. To establish the clinical values of SPECT in ankylosing spondylitis, a study of radiologic evaluation, quantitative bone scan and SPECT have been carried out in 34 patients who were firmly suspected as having ankylosing spondylitis by other tests. This study showed that SPECT could improve the applicability of the imaging modality in the diagnosis and the assessment of disease activity and the capacity of early diagnosis in patients with ankylosing spondylitis. We believe that improved three dimensional localization in and around the sacroiliac joints by SPECT might overcome several diagnostic difficulties. Especially when radiographic abnormalities are not present in the early period, the diagnostic values of SPECT may be more potential.
Diagnosis ; Early Diagnosis ; Evaluation Studies as Topic ; Humans ; Rehabilitation ; Sacroiliac Joint ; Spondylitis, Ankylosing* ; Tomography, Emission-Computed, Single-Photon*

Tuberculosis remains high incidental disease in Korea with an estimated incidence of 2.5% in generalpopulation. Among the tuberculosis of bone, spinal tuberculosis is high incidence and curable disease, but earlytreatment demands early diagnosis. Authors reviewed clinical aspects of 376 cases, and reviewed conventional filmsof 74 cases and CT of 8 cases, confirmed histopathologically as spinal tuberculosis from Jan. 1976 to May 1985 atYonsei medical center, Yonsei University. The results were as follows: 1. The frequent site of involvement werelower thoracic and lumbar vertebra, 4th lumbar vertebra was the most common lesion site among them. 2. Theseperated lesions were 10.2% among spinal lesion. 3. The most common type and pattern of bone density wasintervertebral type and mixed pattern each other. 4. Paravertebral abscess, kyphosis and narrowing ofintervertebral disc space were discovered more than 80% in reviewed conventional films. 5. In children, there isno predilection site. 6. Spinal CT was more accurate diagnostic method than conventional study in the evaluationof following aspects: 1) extent of lesion 2) degree of spinal canal involvement 3) changes of surrounding organ.
Abscess ; Bone Density ; Child ; Early Diagnosis ; Humans ; Incidence ; Korea ; Kyphosis ; Methods ; Spinal Canal ; Spine ; Tuberculosis ; Tuberculosis, Spinal

In Bureger's angiographic findings are not pathognomonic, but in most cases they are diagnostic. We reviewedperipheral angiography of 36 cases of Buerger's disease who were suspected clinically during the period from Jan.1979 to Dec. 1984. The results were as follows: 1. The sex distribution of the cases were 34 males and 2females(17:1) and most common in 4th decade. Eight-six percents of the patients were smokers. 2. Chief complainson admission were ulceration, pain at rest, coldness, and discoloration. 3. The anterior tibial artery wasaffected most commonly (88%) and posterior tibial(76%), peroneal(68%), popliteal(22%), and femoral arteruy(15%) inorder. 4. The angiographic findings were 1) In all cases, there was abscence of arteriosclerotic lesions andshowed smooth vessel walls in non-affected arteries. 2) Direct corkscrew type collaterals were found in 2% of thelesions, and indirect type collaterals in 81%. The tree-root or spider's leg type collaterals were also found in74%. 3) Standing-wave patterns were found in 30% which affected above the popliteal artery. 4) Early venousdrainage was found in 16% of the lesions.
Angiography ; Arteries ; Humans ; Leg ; Male ; Popliteal Artery ; Sex Distribution ; Thromboangiitis Obliterans ; Tibial Arteries ; Ulcer

No abstract available.

The objectives of this study sere to investigate how the local irradiation affect the survival of random pattern skin flap, and whether or not hyperbaric oxygen and allopurional can improve the survival of the irradiated rat skin flap. There have been many reports about the effects of hyperbaric oxygen and allpurinol on skin flaps. However, very few reports have been presented on the effects of hyperbaric oxygen and allpurinol in treating irradiated skin flaps. The author examined the local irradiation effect on rat skin flap survival after irradiation of 20 Gy, 3 days postoperatively, on cranially based random pattern dorsal skin flap, which was 3 x 9cm in size. The flap survival length was measured in experimental groups treated with hyperbaric oxygen (2.5 atm absolute, 100% oxygen, once a day for 7days) after irradiation and with hyperbaric oxygen combined with allopurinol (100mg/kg, once a day for 7 days), in comparison with a radiation-only group. On reviewing the flap survival length 10 days postoperati-vely, the average flap survival length in the radiation-only group was 2.2+/-0.5cm, while in the non-radiation group it was 5.5+/-0.3cm. The reduction ratio of flap survival by irradiation was 60%. There was a significant increase in the mean flap survival length in the groups treated with hyperbaric oxygen (4.0+/-1.6cm) and hyperbaric oxygen combined with allopurinol (5.5+/-1.8cm). The increased ratio of flap survival in each group was 85% and 150% when compared to the radiation-only group. The author found that rat skin flap survival decreased, even at an early stage, as a result of high dose local irradiation and that decreased flap survival by irradiation could be restored by hyperbaric oxygen and allopurinol. The group treated with hyperbaric oxygen combined with allopurinol showed increased flap survival over the group treated with hyperbaric oxygen only. The results showed a method which could possibly increase flap survival in cancer patients who require early radiation after flap surgery.
Allopurinol* ; Animals ; Humans ; Oxygen* ; Rats* ; Skin*

The effect of Atenolol on the blood pressure were studied in 31 cases of essential hypertension and on the effect of plasma renin activity in 8 cases. There were 8 cases of male with age 49.5(42-70) and 23 cases of female with age 49(35-71) years. 27 cases of 31 cases were untreated hypertensive patients and 4 cases were refractory to hypotensive drugs of diuretics and vasodilators. The Atenolol 50mg once-daily was given to all patients orally for 3 weeks. The blood pressure, heart rate, ECG and symptoms were checked in one week interval. In 8 cases, the plasma renin activity was measured by Dainabot Kit before and after one week medication. The results were as follows: 1. In 27 cases of untreated hypertension, the control blood pressure was 182.9/11.4mmHg in average. The blood pressure decreased in average by 18.3/11mmHg in one week, 23.7/15.9mmHg in two week and 21.5/10.5mmHg in three week. The heart rate also decreased by 7.4/min. in one week, 14.9/min. in two week and 7.8/min. in three week. These data showed considerable reduction of blood pressure and heart rate with 50mg Atenolol once-daily. 2. The basal plasma renin activity after one week medication was reduced by 46% in 8 cases and this data showed considerable reduction regardless control level of basal plasma renin activity. 3. There were considerable blood pressure reduction by adding Atenolol 50mg once-daily to diuretics and vasodilator to which patient's blood pressures were refractory. 4. There was no orthostatic hypotension or serious side effect by Atenolol medication.
Atenolol ; Blood Pressure* ; Diuretics ; Electrocardiography ; Female ; Heart Rate ; Humans ; Hypertension* ; Hypotension, Orthostatic ; Male ; Plasma* ; Renin* ; Vasodilator Agents