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Echocardiographic evaluation of left ventricular function permits the demonstration of preclinical diabetic cardiomyopathy. In order to define the relationship between diabetic retinopathy and precence of myocardial dysfunction, M-mode echocardiograms were recorded in three groups of diabetics ; group 1, no retinopathy, group 2, background retinopathy, group 3, proliferative retinopathy, and normal controls without evidence fo coronary heart disease. The resultant traces were digitized, and systolic and diastolic parameters were evaluated. None of parameters fo systolic function was modified. however peak velocity of posterior wall thinning was decreased in group 3(p<0.005), peak velocity of left ventricular demension increase was decreased in all three groups(p<0.005, P<0.001, P<0.001 respectively), duration of rapid thinning of posterior wall increased in group 2 and 3(p<0.001, p<0.001 respectively), and duration of rapid inflow of left ventricle was increased in group 3(p<0.005). These results indicate a diminution of myocardial compliance and relaxation in diabetics with retinopathy. It is concluded that abnormalities of left ventricular diastolic function is present in diabetics when left ventricular systolic function is normal and that more severe abnormalities of left ventricular diastolic function in diabetics with proliferative retinopathy reflect a subclinical diabetic cardiomyopathy due to small vessel disease.
Compliance ; Coronary Disease ; Diabetes Mellitus ; Diabetic Cardiomyopathies ; Diabetic Retinopathy ; Echocardiography* ; Heart Ventricles ; Relaxation ; Ventricular Function, Left*

1.Current trends in the diagnosis and treatment of Graves' disease in Korea.

2.A Study on Left Ventricular Function in Diabetics by Digitized Echocardiography.

3.Lipoproteinelectropheresis pattern in Nephrotic Syndrome.

4.A Case of Thin Basement Membrane Nephropathy.

5.Immunologic Function in Early Phase of Various Glomerulonephritis.

6.Retroperitoneal hematoma with pelivc bone fracture.

7.Antigen analysis of rickettsia typhi isolated in Korea: SDS-PAGE and immunoblotting characters.

8.A case of ateriosclerotic aneurysm of the deep femoral artery

9.Abdominal aortic aneurysm combined with advanced stomach cancer

10.Effects of nitric oxide produced by macrophages on the proliferation of murine lymphocytes stimulated by mitogen.

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