Expression of the pS2 protein in breast carcinoma is a useful guide to evaluate the prognosis and response to tamoxifen. The pS2 protein is an estrogen-regulated 60 amino acid protein which was originally discovered following the screening of cDNA libraries in MCF-7 breast carcinoma cells and is induced through estrogen-dependent transcription of the pS2 gene. The presence of the pS2 protein in breast cancer is considered as valuable as the receptor status, or even more so, in predicting the response to hormonal therapy. We have investigated the pS2 protein expression in 62 cases of primary breast cancer in order to know the relationship between the expression rate of the pS2 protein and hormonal receptor status using immunohistochemical procedures on formalin-fixed and paraffin-embedded tissues. Concomitantly, both the estrogen receptors (ER) and progesterone receptors (PR) were examined using the immunohistochemical technique. Positive staining for the pS2 was seen in forty-nine cases (79%) of the tumors. Forty three cases (88%) of the pS2 positive tumors were ER positive and forty one cases (84%) of the pS2 positive tumors were PR positive ; forty six cases (93%) of pS2 positive tumors were positive for ER and/or PR. The pS2 status correlated significantly with the ER (p<0.0001) and PR (p<0.001). The results reveal a close association between the pS2 protein and either or both the ER and PR status.
Breast Neoplasms* ; Breast* ; Estrogens* ; Gene Library ; Mass Screening ; Progesterone* ; Prognosis ; Receptors, Estrogen ; Receptors, Progesterone* ; Tamoxifen

To evaluate the correlation between the internal echo patterns and henodynamics in hepatic cavernous hemangioma, we compared the interanal echo pattern with the hemodynamic pattern examined by intravenous bolus CT(multi-phase incremental bolus dynamic CT) in 34 diagnosed hemangiomas (25 patients). We classified cavernous hemangiomas as two different hemodynamic patterns according to the findings of the early phase of intravenous bolus CT scans. Early enhancing type means that most portion of a mass is enhanced during the early hpase and late enhancing type means that only minimal peripheral portion of a mass is enhanced during the early phase. We classified ultrasonogrphic patterns as hypoechoic and hyperechoic according to main echogenicity of the mass. The late enhancing type tends toward the high echo type (20/21) and the early enhancing type tends to ward the low echo type (11/13) (p<0.01) Therefore, we believe that the early enhancing type which represents rapid contrast inflow toward mass, contains large portions of cavernous space and showes hypoechoic, but late enhancing type which represents late contrast inflow toward a mass, contains large portions of fibrous space and showes hyperechoic. In conclusion, there was significant correlation between internal hemodynamics and echo patterns in hepatic cavernous hemangioma.
Hemangioma ; Hemangioma, Cavernous* ; Hemodynamics* ; Tomography, X-Ray Computed

To evaluate the correlation between the internal echo patterns and henodynamics in hepatic cavernous hemangioma, we compared the interanal echo pattern with the hemodynamic pattern examined by intravenous bolus CT(multi-phase incremental bolus dynamic CT) in 34 diagnosed hemangiomas (25 patients). We classified cavernous hemangiomas as two different hemodynamic patterns according to the findings of the early phase of intravenous bolus CT scans. Early enhancing type means that most portion of a mass is enhanced during the early hpase and late enhancing type means that only minimal peripheral portion of a mass is enhanced during the early phase. We classified ultrasonogrphic patterns as hypoechoic and hyperechoic according to main echogenicity of the mass. The late enhancing type tends toward the high echo type (20/21) and the early enhancing type tends to ward the low echo type (11/13) (p<0.01) Therefore, we believe that the early enhancing type which represents rapid contrast inflow toward mass, contains large portions of cavernous space and showes hypoechoic, but late enhancing type which represents late contrast inflow toward a mass, contains large portions of fibrous space and showes hyperechoic. In conclusion, there was significant correlation between internal hemodynamics and echo patterns in hepatic cavernous hemangioma.
Hemangioma ; Hemangioma, Cavernous* ; Hemodynamics* ; Tomography, X-Ray Computed

Generalized pustular psoriasis is a severe form of paoriasis and is frequently associated with arthritis and nail deformity. We present a case of generalized pustular psoriasis in a 40 year-old man, with nail change, arthritis of both knee and ankle joints, spondylitis, and glomerulonephritis. We found a positive results of HLA A-9, B-27 in this patient. Skin lesions, arthralgia and hematuria improved marked1y by plasmapheresis and application of topical corticostertoid.
Adult ; Ankle Joint ; Arthralgia ; Arthritis* ; Congenital Abnormalities ; Glomerulonephritis* ; Hematuria ; Humans ; Knee ; Plasmapheresis ; Psoriasis* ; Skin ; Spondylitis*

Kaposi's sarcorna is a tumor-like condition which characterized by a mixed proliferation of fibroblastic components and vascular structures. The authors report a case of nodular type of Kaposis sarcoma in 54 year-old male who had an eroded hemorrhagic nodule and few papular lesions. These lesions involved only both hands and feet without systemic involvement.
Cytochrome P-450 CYP1A1 ; Fibroblasts ; Foot ; Hand ; Humans ; Male ; Middle Aged ; Sarcoma* ; Sarcoma, Kaposi

We described a 65-year-old woman with a papule on the left temple area of } year duration. The lesion showed typical findings of atypical fibroxanthoma and was located on the lesion of solar keratosis, So sunlight may be the most important one among the various insults to atypical fibroxanthoma of the skin.
Aged ; Female ; Humans ; Keratosis ; Skin ; Sunlight

Congenital agenesis of the right lobe of liver is a rare anomaly and only 33 cases have been reported. CT showed absence of the right lobe of liver and compensatory hypertrophy of the other lobe. We report the CT findings of a new case of this anomaly with a review of the literatures.
Hypertrophy ; Liver*

Cheilitis glandularis simplex, the clinical term first defined by Puente and Acevedo in 1935, is characterized by the development of hyperplastic mucous glands in the lips, associated with dilated ductal canals; it is manifested clinically by a usually painless swelling of the lips and a variably constant, bothersome, sticky mucoid discharge. Recently we have experienced a case of cheilitis glandularis simplex in a 13-year-old boy and an excellent cosmetic result was obtained after surgical excision and repair.
Adolescent ; Cheilitis* ; Humans ; Lip ; Male

Magnetic resonance (MR) is rapidly emerging technique that provides high quality images and potentially provides much more diagnostic information than do conventional imaging modalities. MRI is conceptually quite different from currently used imaging methods. The complex nature of MRI allows a great deal of flexibility in image production and available information, and key points are as follows. 1. MR offers a non-invasive technique with which to generate in vivo human images without ionizing radiation and with no known adverse biological effects. 2. Imaging mechanism of MRI is quite different from conventional imaging modality and for more accurate diagnostic application, It is necessary for physician to understand imaging mechanism of MRI 3. M.R. makes available basic chemical parameters that may provide to be useful for diagnostic medical imaging and more specific pathophysiologic information which are not available by alternate techniques. 4. M.R. can be produced by number of different methods. This flexibility allows the imaging technique to be applicated for particular clinical purpose. Multiplanar and three dimensional imaging may extend the imaging process beyond the single section available with current CT. 5. Future directions include efforts to; a. Further development of hard ware b. More fastening scan time c. Respiratory and cardiac gated imaging d. Imaging of additional nuclei except hydrogen. e. Further development of contrast media f. MR in vivo spectroscopy g. Real time MR imaging
Comprehension* ; Contrast Media ; Diagnostic Imaging ; Humans ; Hydrogen ; Magnetic Resonance Imaging ; Pliability ; Radiation, Ionizing ; Spectrum Analysis

The cutaneous metastaaes from carcinoma of breast produce four definite clinical types: inflammatory carcinoma, telangiectatic carcinoma, nodular carcinoma, and carcinoma en cuirasse. We present a case of 51-year-old woman who had purpuric, hard, sclerotic plaque with ulceration, crust and. several pea-sized hemorrhagic papulovesicular eruptions on the right chest wall for one year. Histopathological findings show metastatic ductal carcinoma but, the primary focus was not determined.
Breast ; Carcinoma, Ductal ; Female ; Humans ; Middle Aged ; Thoracic Wall ; Ulcer