1.A comparative study on subgingival microbial composition between natural teeth and osseointegrated implants.
Yong Sik LIM ; Yung Soo KIM ; Chang Whe KIM
The Journal of Korean Academy of Prosthodontics 1993;31(3):411-422
No abstract available.
Tooth*
2.MR angiography of the renal arteries.
Sang Hoon BAE ; Gwy Suk SEO ; Chang Sik LIM ; Ku Sub YUN ; Kyung Hwan LEE ; Hyo Keun LIM
Journal of the Korean Radiological Society 1993;29(1):77-85
We reviewed MR angiograms to evaluate its efficacy for visualizing the renal arteries and detecting renovascular disease. 41 renal arteries in 19 patients were examined by MR angiography. 3-D time-of-flight technique was used as routine examination method for MR angiography and 2-D time-of-flight technique was added in some particular cases to visualize venous flow. Within two weeks after MR angiography was performed, 23 renal arteries in 10 patients were additionally examined by conventional angiography or intraarterial DSA. The success rates of vessel visualization on MR angiography in normal renal arteries were 100% in main 67.7% in segmental, and 11.8% in intrarenal arteries. As a result of comparative study in normal main renal arteries with MR angiograms and conventional angiograms, overall correspondence in the number and the shape was noted and the caliber discrepancy between two examination did not exceed 3.0 mm. one arteriovenous fistula with aneurysm, one stenotic artery and two occluded arteries were well evaluated One arteriovenous fistula with aneurysm, and two occluded arteries were well evaluated by MR angiography. However three stenotic lesions were misdiagnosed as occlusions on MR angiography. and the overall accuracy was 87%. We conclude that MR angiography has the potential to be a noninvasive and useful screening method for determining the number of renal arteries and for detection of abnormalities of main renal arteries.
Aneurysm
;
Angiography*
;
Arteries
;
Arteriovenous Fistula
;
Humans
;
Mass Screening
;
Methods
;
Renal Artery*
3.Expression of Matrix Metalloproteinase-2 and -9 in Oral Squamous Cell Carcinomas in Relation to the Histologic Invasiveness and Cellular Differentiation.
Seong Doo HONG ; San Pyo HONG ; Yong Sik KIM ; Jae Il LEE ; Chang Yun LIM
Korean Journal of Pathology 1999;33(4):243-250
A poor prognosis of oral squamous cell carcinoma (SCC) is partly due to the invasiveness and metastasis of the tumor. A key element in tumor invasion and metastasis in the degradation of extracellular matrix is matrix metalloproteinases (MMPs). This study was performed to determine the expression of MMP-2 and MMP-9 of oral SCCs with regard to the histologic invasiveness and differentiation in 5 normal oral mucosa and 36 oral SCCs. The histologic invasiveness of oral SCCs were classified into 4 grades. The differentiation of oral SCCs was divided into 3 grades. The streptavidin-biotin immunohistochemical staining, using MMP-2 and MMP-9 monoclonal antibodies, was performed to determine the expression of MMP-2 and MMP-9. The expression of MMP-2 was positive in 6 of 17 oral SCCs with weak invasiveness and was positive in 7 of 19 oral SCCs with strong invasiveness. The MMP-2 expression did not increase significantly with respect to the invasiveness of oral SCCs (P>0.05). The expression of MMP-9 was strongly positive in 6 out of 17 SCCs with weak invasiveness and was strongly positive in 14 of 19 SCCs with strong invasiveness. The MMP-9 expression increased significantly with respect to the invasiveness of oral SCCs; the stronger the expression, the stronger the invasiveness (P<0.05). The expression of MMP-9 was in 57.9% of well differentiated SCCs, 57.1% of moderately differentiated ones, and 33.3% of poorly differentiated SCCs. The expression of MMP-2 and MMP-9 did not increase significantly with respect to the histologic differentiation. We conclude that with respect to the invasiveness, the MMP-9 expression increases significantly in oral SCCs but the MMP-2 expression does not; and that with respect to the histologic differentiation, their expressions do not increase significantly. These results suggeste that MMP-9 can be used as a tool to evaluate the invasiveness of oral SCCs.
Antibodies, Monoclonal
;
Carcinoma, Squamous Cell*
;
Extracellular Matrix
;
Matrix Metalloproteinase 2*
;
Matrix Metalloproteinases
;
Mouth Mucosa
;
Neoplasm Metastasis
;
Prognosis
4.Study of nasal resistance by rhinomanometry.
Uk LIM ; Chang Sik SHIN ; Kyung Rae KIM ; Hyung Seok LEE ; Sun Kon KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(4):672-682
No abstract available.
Rhinomanometry*
5.Amelia of Both Lower Extremities: A Case Report
Jong Sun LIM ; Yoon Soo KIM ; Young Sik PYUN ; Chang Soo KANG ; Ik Dong KIM
The Journal of the Korean Orthopaedic Association 1972;7(4):477-480
A case of amelia, which affected upon both lower extremities, was experienced at the Taegu Presbyterian Hospital. We report this case because of rarity of amelia and an addition of the case with brief review of literatures.
Daegu
;
Ectromelia
;
Lower Extremity
;
Protestantism
6.Radiological aspect of pancreatic pseudocysts
Tae Sub CHUNG ; Sue Jin LIM ; Hyung Sik YOO ; Jung Ho SUH ; Chang Yun PARK
Journal of the Korean Radiological Society 1982;18(2):306-315
Pancreatic pseudocyst occurs as a complication of pancreatitis or trauma, which results in the escape of pancreatic enzymes from the parenchyma or ductal system of pancreas. At that time, serum amylase may have returned to normal level, and the patient may be subjectively asymptomatic. In this phase, the radiologic findings are relatively greater significance than laboratory data. In the conventional radiologic study, pancreatic pseudocyst have been frequently confused with other retroperitoneal mass, but recently with clinical application of ultrasound and CT scan, more accurate diagnosis can be obtained. The brief results are as follows; 1. Male to female ratio was 3:2 in 15 patients. Incidence was most common in young adult age. Most frequent symptom was epigastic pain, and which was noted in 11 cases of patients. 7 cases of patients had past history of abdominal trauma and past history of pancreatitis was only in 1 case. Most common laboratory finding was leukocytosis in 8cases of patients and elevated serum amylase was also noted in 7 cases. 2. In each 5 cases of patients, plain chest roentgenologic evidence of left side pleural effusion and hemidiaphragm elevation were observed. 3. On flat abdomen film, soft mass shadow was visualized in 8 cases of patients. On UGI series, evidence of retrogastric space widening was observed in 11 cases of patients. 4. The location of pseudocyst is mainly in body and tail of pancrease in 11 cases of patients. 5. More accruable diagnosis can be obtained through application of ultrasound and CT scan.
Abdomen
;
Amylases
;
Diagnosis
;
Female
;
Humans
;
Incidence
;
Leukocytosis
;
Male
;
Pancreas
;
Pancreatic Pseudocyst
;
Pancreatitis
;
Pancrelipase
;
Pleural Effusion
;
Tail
;
Thorax
;
Tomography, X-Ray Computed
;
Ultrasonography
;
United Nations
;
Young Adult
7.Drug - Induced Esophageal Ulcers.
Han Lim MOON ; In Sik CHUNG ; Sang Hong BAEK ; Kyu Sik SHIM ; Chang Don LEE ; Suk Won HAN ; Kyu Won CHUNG ; Hee Sik SUN ; Whan Kook CHUNG
Korean Journal of Gastrointestinal Endoscopy 1985;5(1):11-15
Over 26 kinds of tablets and capsules, such as Tetracycline, Quinidine and Potassium preparations were reported to cause esopbageal ulcerations, eharacterized in various size, shape and number, ind sually in mid-esophagus, Recently authors experienced 10 cases of drug-induced esophageal ulcerations due to antibiotics and antiinflammatory agents such as Tetracycline, Aspirin, etc. Four cases were men and six were women. Four cases were in third dades, three in fourth cleeades, two in fifth decades and one in sixth decades. Presenting symptoras were odynophagia(4/10), dysphagia(3/10), substernal pain(7/10) and epigastric pain(3/10). Endoscopic examination of the esophgus showed single or multiple, small and shallow ulcers on the mid-esophgeal mucosa at the level of 30cm from the ineisor in eight cases, one Iarge and deep ulcer at the level of 40cm from incisor in one patient and one amall, shallow and one large, deep ulcers at the same time. in one patient The shape of alcers were various from a round to a large horseshoe shaped one. The clinical course was mild without complications. It was suggested that drug-induced esophsgeal ulcers with antibiotics and antiinflammatory agents could be found frequently and they had benign and mild clinicalc ourse,
Anti-Bacterial Agents
;
Anti-Inflammatory Agents
;
Aspirin
;
Capsules
;
Female
;
Humans
;
Incisor
;
Male
;
Mucous Membrane
;
Potassium
;
Quinidine
;
Tablets
;
Tetracycline
;
Ulcer*
8.The role of CDI on the antigen recognition of human CD3+CD4-CD8 T lymphocyte clone specific to M.tyberculosis.
Myung Sik CHOI ; Ju Young SEOH ; Dong Gyun LIM ; Ik Sang KIM ; Woo Hyun CHANG ; Chang Yong CHA
Journal of the Korean Society for Microbiology 1993;28(6):505-519
No abstract available.
Clone Cells*
;
Humans*
;
Lymphocytes*
9.The Effect of a Priming Dose of Atracurium on the Onset Time in Rapid Sequence Tracheal Intubation.
Chang Gyu HAN ; Kwan Sik KIM ; Sung Sik PARK ; Dong Gun LIM ; Jin Woong PARK
Korean Journal of Anesthesiology 2003;45(3):321-325
BACKGROUND: Depolarizing muscle relaxant, frequently used for rapid sequence endotracheal intubation in clinical field, has serious complication that occur intermittently, such as, hyperkalemia, increased intraoccular pressure and sudden cardiac arrest, especially in infants and adolescents. So the priming principle, i.e., the administration of a subparalyzing dose of a nondepolarizing muscle relaxant (priming dose) prior to the intubating dose, was developed for rapid sequence endotracheal intubation with nondepolarizing muscle relaxant. However, the priming dose sometimes causes complications, such as, swallowing difficulty or pulmonary aspiration, and this can cause patient discomfort or fatal complications. In this study we examined proper atracurium priming dose and evaluated possible complications of priming doses. METHODS: One hundred patients, scheduled for elective surgery were randomly allocated into five groups according to the priming dose used (group 1; 0, group 2; 0.03, group 3; 0.06, group 4; 0.09, group 5; 0.12 mg/kg). Patients received a midazolam and fentanyl injection, the base line TOF ratio was measured, and an intubating dose was given. We also examined changes in vital sign for 20 minutes after injection and noted the time when the twitch height became zero (onset time). RESULTS: In group 1, the onset time was 107 +/- 22.9 sec, and in groups 4 and 5, the onset times were 85.0 +/- 15.6 and 69.9 +/- 19.3 sec, respectively. But, in group 5, some patients showed tachycardia and swallowing difficulty. CONCLUSIONS: The optimal priming dose of atracurium was determined as 0.09 mg/kg, in most cases, however patients sensitivity to the atracurium should be considered.
Adolescent
;
Atracurium*
;
Death, Sudden, Cardiac
;
Deglutition
;
Fentanyl
;
Humans
;
Hyperkalemia
;
Infant
;
Intubation*
;
Intubation, Intratracheal
;
Midazolam
;
Tachycardia
;
Vital Signs
10.Massive Gastrointestinal Bleeding Following Intracranial Lesion.
Ho Young LIM ; Jo Young KIM ; Jong Oung DOH ; Kyung Sik CHANG
Journal of Korean Neurosurgical Society 1982;11(3):317-326
"Stress ulceration" of the stomach and duodenum is a nonspecific term used to cover a wide variety of different entities. It has been known for many years that there is an association between gastrointestinal bleeding and intracranial lesion. This is not a common clinical problem, but it has been noted to be increasing over the recent years, possibly due to the increased survival of severe injured neurosurgical patients and neurosurgical procedures. Clinically recongnition of gastrointestinal bleeding or ulceration can be difficult, partcularly in the unconscious patient and prevention of this complication has not been successful. The treatment of that has been the subject of considerable controversy. Prognosis depends on a prevention of hemorrhagic shock or sepsis and promptly proper management. The authors analyzed the 21 cases of massive gastrointestinal bleeding in neurosurgical patients, who were admitted to the department of neurosurgery of National Medical Center from 1978 to 1980.
Duodenum
;
Early Diagnosis
;
Hemorrhage*
;
Humans
;
Neurosurgery
;
Neurosurgical Procedures
;
Prognosis
;
Sepsis
;
Shock, Hemorrhagic
;
Stomach
;
Ulcer