1.Pemphigus Vulgaris Developed During Pregnancy.
Chang Woo LEE ; Seon Hoon KIM ; Hee Joon YU
Korean Journal of Dermatology 1981;19(1):99-103
We present a case of pemphigus vulgaris developed during pregnancy. The clinical features of this patient were similar to those of hetpes gestationis. By immunofluorescence studies we found that the patient's serum contained autoantibodies to intercellular substance of epidermis. Direct immunofluorescence microscopy of a perilesional skin also demontrated immunoglobulin deposition in the intercellular areas. Additionally we did in vitro C3 staining for further confirmation of the diagnosis but it was negative in basement membrane zone. This patient was initially treated with corticosteroid and azathioprine. Several months later gold compound was given instead of azathioprine and corticosteroid with good therapeutic response.
Autoantibodies
;
Azathioprine
;
Basement Membrane
;
Diagnosis
;
Epidermis
;
Fluorescent Antibody Technique
;
Fluorescent Antibody Technique, Direct
;
Humans
;
Immunoglobulins
;
Microscopy
;
Pemphigus*
;
Pregnancy*
;
Skin
2.The clinical and histopathological studies on ovarian tumors.
Sung woon CHANG ; Seon Kyung LEE ; Seoung Bo KIM ; Jae Hyun LEE ; Jung Eun MOK
Korean Journal of Obstetrics and Gynecology 1993;36(7):1073-1083
No abstract available.
3.Papulosquamous Skin Lesions in Systemic Lupus Erythematosus.
Seon Jong KIM ; Young Suck RO ; Hee Chul EUN ; Chang Woo LEE
Korean Journal of Dermatology 1990;28(6):774-778
We present 6 patients with systemic lupus erythematosus who had papulosquamous skin lesions. These skin lesions were consistent with the findings of subacute cutaenous lupus erythematosus(SCLE) clinically and histopathologically. The. distribution of the skin lesions were on the face, upper extremities and upper trunk in one group, and the upper and lower extremities in other group of these patients. After confirmation of the skin lesions as a type of SCLE, they were regressed with anti-malarial and/or systemic corticosteroids, within 2 months in all patients. For the better management of the patient with lupus erythematosus, understanding of clinically distinct LE-specific skin lesions, including the papulosquamous cuta-neous manifestation of SCLE, may be necessary.
Adrenal Cortex Hormones
;
Humans
;
Lower Extremity
;
Lupus Erythematosus, Systemic*
;
Skin*
;
Upper Extremity
4.Antrochoanal polyp: CT findings.
Seon Kwan JUHNG ; Kyoung Soo LEE ; Chang Guhn KIM ; Jong Jin WON ; Chul Ho JANG
Journal of the Korean Radiological Society 1992;28(4):537-540
An antrochoanal polyp is a solitary polypoid mass that arises from the maxillary sinus, and protrudes through the natural ostium into the middle meatus, and reaches the choana, The polyp does not differ histologically from an ordinary nasal polyp, which is composed of edematous, hyperplastic submucosal connective tissue stroma, and is relatively hypocellular, In this sequence of events. Its computed tomographic(CT)findings are characteristic. We retrospectively analyzed CT studies of nine cases, all of which showed similar CT findings; a solitary, homogeneous, hypodense mass without bony destruction that extends from the maxillary sinus through the widened ostium into the choana.
Connective Tissue
;
Maxillary Sinus
;
Nasal Polyps
;
Polyps*
;
Retrospective Studies
5.The Use of Transesophageal Echocardiography for Pulmonary Artery Catheter Placement: Two cases.
Byung Ho LEE ; Jun Seok CHEA ; Chang Jae KIM ; Mee Young CHUNG ; Seon Heu SEO
Korean Journal of Anesthesiology 1997;33(5):953-956
The transesophageal echocardiography (TEE) has been used for the assessment of right and left ventricular function, valvular structure and function, regional wall motion abnormalities and localization of intravascular catheters, cannular and prosthesis. We inserted the pulmonary artery catheter (PAC) under the guidance of intraoperative TEE because of the difficulty of placing PAC with the pressure tracing method in two patients. The PAC was inserted from right atrium to right ventricle with the basal four chamber view and advanced to pulmonary artery through pulmonary valve with the longitudinal view of TEE. We observed typical pulmonary arterial wave form to confirm the correct position. We suggest that the TEE can be used for successful placement of a PAC to facilitate manipulation of the catheter as an alternative method in the patients whose PAC can not be positioned with the pressure tracing method.
Catheters*
;
Echocardiography, Transesophageal*
;
Heart Atria
;
Heart Ventricles
;
Humans
;
Prostheses and Implants
;
Pulmonary Artery*
;
Pulmonary Valve
;
Ventricular Function, Left
6.Mucous Gland Adenoma of the Bronchus; Light Microscopic and Ultrastructural Features.
Mi Seon KWON ; Kyo Young LEE ; Young Shin KIM ; Chang Suk KANG ; Sang In SHIM
Korean Journal of Pathology 1997;31(9):898-901
We present a case of mucous gland adenoma arising from the main bronchus of the lower lobe of the left lung in terms of clinicopathologic, immunohistochemical, and ultrastructural aspects as well as review of related literatures. The patient, a 31-year-old female, was admitted to Catholic University Medical College Hospital with complaints of coughing and purulent sputum for about seven years. The chest CT showed a severely calcified tumor in the left lower lobe of the lung. Grossly, the calcified tumor arising from the main bronchus protruded into the lumen and showed bronchiectasis of the lower lobe and atelectasis of the upper lobe of the lung. The tumor was pale brown-gray and sharply circumscribed and showed some small cystic spaces filled with mucoid material. Microscopically, most of the tumor showed dystrophic calcification. The growth pattern of the tumor is composed of cysts, tubules, and glands lined by cytologically bland columnar, cuboidal, or flattened mucus secreting cells. Electron micrograph of tumor cells showed some round or oval mucous granules measuring 0.5-1.8 micrometer.
Adenoma*
;
Adult
;
Bronchi*
;
Bronchiectasis
;
Cough
;
Female
;
Humans
;
Lung
;
Mucus
;
Pulmonary Atelectasis
;
Sputum
;
Tomography, X-Ray Computed
7.Ultrastructural Changes of the Bile Canaliculi after Common Bile Duct Ligation.
Kook Seon YOO ; Suk Hee LEE ; Hee Kyung PARK ; Chang Ho CHO ; Jong Min CHAE
Korean Journal of Pathology 1996;30(3):175-183
The purpose of this study was to investigate the morphologic changes of the bile canaliculi and its associated structures of the liver induced by common bile duct ligation(CBDL) in the rat. The canalicular surface and lateral surface of the dry-fractured hepatocytes was studied with scanning electron microscopy at 1~6 weeks post ligation. The first week after CBDL, the bile canaliculi were dilated. The microvilli were increased in number and the lumens contained granular materials After 2 weeks or more, the bile canaliculi were dilated to a variable degree, and with irregularity, measuring from 1.5 to 5 micrometer in diameter, and in the advanced stage, the canaliculi showed blunting and the disappearance of microvilli. Some canaliculi had sprouting side branches. At 4~6 weeks post-ligation, the lateral surface of the hepatocytes also showed some irregularity and a tortuous appearance, and numerous small sized microvillous projections were formed. The tubular structures of the proliferated SER distributed adjacent to the lateral surface of the hepatocytes, and the direct connection of a tubular structure and the cytoplasmic membrane was observed. These results suggest that the deformity and loss of microvilli of bile canaliculi reflect the disturbance of bile secretion from the hepatocytes. And prolonged obstruction of bile flow may result in bile excretion via the lateral surface of hepatocytes.
Rats
;
Animals
8.The Relationship between Height and Body Weight and Penile Size in University Students.
Jong Seon YOON ; Gil Ho LEE ; Dae Soo CHANG
Korean Journal of Urology 1998;39(11):1061-1064
PURPOSE: Is there any relationship between penile size and physical stature? This study was performed to answer this question and provide guidelines of penile size to assist in counseling patients for penile augmentation. MATERIALS AND METHOD: Penile size, body weight and height were measured in 150 young healthy men, and the body mass index(BMI) was calculated in weight(kg)/height(m)2. The penile length and circumference were measured with tape in flaccid and erect states. The 'lengthening ratio' was calculated by 'erect length/flaccid length', and 'tumescent ratio' was calculated by 'erect circumference/flaccid circumference'. All the data was statistically evaluated and the following results were obtained. Result : The average length and circumference were 8.26+/-1.07cm and 8.34+/-1.03cm respectively in the flaccid state, and 13.42+/-1.38cm and 11.17+/-1.05cm in the erect state. The average lengthening and tumescent ratios were 1.64+/-0.22 and 1.35+/-0.08, and were negatively correlated to the flaccid penile length and circumference. Height was positively correlated to erect penile length and lengthening ratio. There was a relationship between body weight and erect penile length in a positive direction, but with other penile parameters there were none. There was no relationship between BMI and any parameters of penile size. However, the erect penile length of the normal BMI group was longer than that of the lower BMI group. CONCLUSIONS: The results show that the flaccid penile size is related to the erect penile size and there is some relation between penile size and physical stature. We believe these results will be applicable to the penile augmentation.
Body Size
;
Body Weight*
;
Counseling
;
Humans
;
Male
9.Immunohistochemical Findings in 10 Cases of Inflammatory Myofibroblastic Tumor.
Soo Jin JUNG ; Mi Seon KANG ; Chang Hoon LEE ; Sook Hee HONG ; Hye Kyoung YOON
Korean Journal of Pathology 1999;33(9):717-722
A wide range of denomination has been used for inflammatory myofibroblastic tumor (IMT). IMT is not entirely homogeneous, even though it shows some overlapping histologic features such as haphazard proliferation of spindle cell and polymorphic chronic inflammatory cell infiltraion. The spindle cell is considered to be of myofibroblastic origin but follicular dendritic cell origin was reported recently. IMT is known as nonneoplastic, aberrant inflammatory response. However, IMT could show local invasion, recurrence, vascular invasion, and malignant transformation, and clonal characteristics and aneuploidy of IMT support the hypothesis that IMT may be a neoplastic process. In order to define the nature of spindle cell of IMT, immunohistochemical stains for smooth muscle actin (SMA), vimentin (VMT), lysozyme, S-100 protein, cytokeratin, CD21 were done. Additional immunohistochemical stains for MIB-1 for proliferating activity and LMP (latent membrane protein) for Epstein-Barr virus (EBV) were done. IMTs were composed of each 2 cases from lung, liver and lymph node and one case from common bile duct, maxillary sinus, bladder and thigh, and were histologically subclassified according to Coffin et al. Nine cases (90%) were positive for SMA and VMT, but no correlation between SMA and VMT immunoreactivity and histologic types was identified. Five cases (50%) were positive for lysozyme and S-100 protein, and histologic type III was negative for lysozyme and S-100 protein, and immunoreactivity for S-100 protein was different according to the histologic subtypes. All 11 cases were negative for CD21 and EBV LMP. MIB-1 labelling index was less than 1% in all cases. In summary, the spindle cell is regarded as myofibroblastic origin rather than follicular dendritic cell origin. Relationship with EBV is not clear, and negligible MIB-1 reaction suggests that IMT might have a good prognosis.
Actins
;
Aneuploidy
;
Coloring Agents
;
Common Bile Duct
;
Dendritic Cells, Follicular
;
Herpesvirus 4, Human
;
Immunohistochemistry
;
Keratins
;
Liver
;
Lung
;
Lymph Nodes
;
Maxillary Sinus
;
Membranes
;
Muramidase
;
Muscle, Smooth
;
Myofibroblasts*
;
Prognosis
;
Recurrence
;
S100 Proteins
;
Thigh
;
Urinary Bladder
;
Vimentin
10.Pulmonary Adenocarcinoma of Fetal Type: Report of a case.
Soon Bong CHUNG ; Il Seon LEE ; Hee Kyung CHANG ; Bang HUR ; Man Ha HUH
Korean Journal of Pathology 1992;26(2):186-190
Adenocarcionma of fetal type is in lung is a newly recognized malignant tumor sharing morphologic features with the epithelial component of the pulmonary blastoma devoid of sarcomatous component. We present a case of adenocarcinoma of fetal type in a 28-year-old female, consisting of numerous branching tubules or glands and morula-like epithelial complexes. Histologically, the tubules and glands were composed of glycogne-rich nonciliated epithelial cells showing in part argyrophilia. Some of tubular and morula-like epithelial cells revealed immunoreactivity for neuron-specific enolase. We report this case with a review of literatures with special references on the histogenisis. This report is the pathologically confirmed second case of the pulmonary adenocarcinoma of fetal type in Korea, following the report of Cho and Lee, 1990.
Female
;
Humans
;
Adenocarcinoma