This study was performed in order to explore the immunologic relationship between the skin lesions induced by the human serum and the lymphatic organs. For these purposes, the authors induced the dermatitis in the rabbits by the injections of pooled human serum with Freunds complete adjuvant into the skin, and administered prednisolone and azathioprine as immunosuppressive drugs to the rabbits. Immunologic asmy was performed by the measurement of the plasma ceIls and immunogobulin-bearing B lymphocytes in lymph node and spleen. The results were as follows: 1. By the injections of human serum pyroninophilic cells and immunoglobulining B lymphocytes in lymph node and spleen were increased. 2. By the administrations of prednisolone and azathioprine, pyroninophilic cells and immunoglobulin-bearing B lymphocytes in lymph node and spleen were all decre RSCd.
Azathioprine ; B-Lymphocytes ; Dermatitis* ; Humans ; Immunoglobulins ; Lymph Nodes ; Plasma ; Prednisolone ; Rabbits* ; Skin ; Spleen

We report a case of mycosis fungoides in a 37 year-old male patient who had relatively well defined, irregular, erythematous plaques covered with acales on the buttock, lower extremities, anterior chest and back. Histopathological findings showed epidermotropism and Pautrier microabscesses in the epidermis and infiltration of atypical lymphocytes in the upper dermis. Electron microscopic findings showed mycosis cells with convoluted nuclei and prominent nucleolei He had been received PUVA therapy combined with topical and systemic corticosteroid for 4 months. Skin lesions were improved markedly after treatment with total 262 joules/crn2 and then maintained with 14 joules/cm2 in every week.
Adult ; Buttocks ; Dermis ; Epidermis ; Humans ; Lower Extremity ; Lymphocytes ; Male ; Mycosis Fungoides* ; PUVA Therapy ; Skin ; Thorax

Fine needle aspiration biopsy cytology (FNA) for diagnosis of a variety of breast tum- ors has been proven to be a simple, safe, and cost saving diagnostic methodology with high accuracy. Cytologic specimens from 1,029 fine needle aspirations of the breast during last 3-year period were reviewed and subsequent biopsies from 107 breast lesions were reevaluated for cytohistological correlation. FNA had a sensitivity of 81.6% and a specificity of 98.3%. One out of 107 cases bio- psied revealed a false positive result (0.9%) and the case was due to misinterpretation of apocrine metaplastic cells in necrotic backgound as malignant cells. A false negative rate was 8.4% (9 of 107 cases biopsied). Six of 9 false negative cases were resulted from insufficient aspirates for diagnosis, and remaining three of 9 false negative cases revealed extensive necrosis with no or scanty viable cells on smears. The results indicate that for reducing false positive and false negative rates of FNA, an experienced cytopathologist and a proficient aspirator are of great importance.
Adenoma, Pleomorphic ; Aspirations (Psychology) ; Biopsy ; Biopsy, Fine-Needle ; Breast ; Carcinoma, Adenoid Cystic ; Carcinoma, Mucoepidermoid ; Child* ; Cost Savings ; Diagnosis ; Humans ; Necrosis ; Needles ; Sensitivity and Specificity ; Urinary Tract Infections* ; Urinary Tract* ; Vesico-Ureteral Reflux*

No abstract available.

Angiofollicular lymph node hyperplasia(AFLNH) was first described in 1956 by Castleman et al. It was initially reported as a solitary mediastinal mass but multicentric and extranodal disease is now well known. Histologically two distinct variants, e.g. the hyaline vascular type and the plasma cell type, of AFLNH are recognized. And the plasma cell type is typically associated with clinical syndrome consisting of fever, anemia, elevated erythrocyte sedimentation rate and polyclonal hypergammaglobulinemia. Recently, we experineced three cases of AFLNH. Histologically, two cases were hyaline vascular type, that were presented as a right supraclavicular mass of 49-year-old female, and as an anterior mediastinal mass of 53-year-old female. The remaining one case was plasma cell type that was presented as a left axillary mass of 63-year-old male. The former two cases showed typical features of hyaline vascular type but in case 1, exuberant proliferation of hyalinized vessels of capillary size was characteristic feature. The latter case of plasma cell type characteristically showed clinical syndrome consisting of fever, hypoalbuminemia, polyclonal hypergammaglobulinemia. All cases were presented as a single mass and they were well after surgical excision.
Female ; Humans

The multistage maximal exercise test was performed to 135 cases with various heart disease and 207 control group between jan. 1980 and Dec. 1980 in KoreaGeneral Hospital. The change of heart rate, blood pressure and ST segment in various heart disease were compared with those in control group. The results were followings; 1. There were 130 male and 77 female of cases with control group, whose mean age were 50 years old. 2. General check up was the most common underlying disease of control group(67 patients) and the others were gastritis (28), neurosis (24), diabets mellitus (17), hepatitis (4) and peptic ulcer (4) frequency. 3. Change of heart rate, blood pressure and ST segment in control group during GXT were 89~154, 119/80~157/88 mmHg and 0.6~2 mm. 4. There were 81 male and 51 female of cases with various heart disease group, whose mean age were 50 years old. 5. Atherosclerotic heart disease was the most common underlying disease of various heart disease group (49 patients) and the others were hypertension (34), hypertensive cardiovascular disease (22), labile hypertension (14), angina (7), arrythmia (6) and others (3) in frequency. 6. Change of heart rate, blood pressure and ST segment in various heart disease group during GXT were 85~148, 140/93~178/102 mmHg and -0.7~1.3mm. ST segment in atherosclerotic heart disease, hypertension, hypertensive cardiovascular disease, valvular heart disease and myocardial infarction were significantly depressed(p<0.05) compared with ST segment in control group.
Arrhythmias, Cardiac ; Blood Pressure ; Cardiovascular Diseases ; Exercise Test* ; Female ; Gastritis ; Heart Diseases* ; Heart Rate ; Heart Valve Diseases ; Heart* ; Hepatitis ; Humans ; Hypertension ; Male ; Middle Aged ; Myocardial Infarction ; Peptic Ulcer

Carbon monoxide (CO) is a kind of freq uent toxic gas around our living lives, for common use of briquet as fuel, and its pathologic effect has been known due to mainly hypoxia and direct cytotoxicity in some part to almost all organs, especially to the brain and heart. Some authors have reported pathologic and anatomic changes of the acute of posioning, although in a few cases, that bilaterally symmetrical lesions of the globus pallidus or cerebral white matter regarded as typical. After using computed tomography (CT), those findings have been discovered more easily and acurately. Authors analysed CT find ings of 32 cases, who had a history of acute CO posioning and performed CT at Hanyang University Hospital from May 1979 to June 1983. The results were as follows: 1. Of all 32 cases with CT scan, low density lesions were demonstrated in 28 cases (88%) and others were hemorrhagic and calcified in 2(6%), respectively. 2. AII lesions were seen as bilaterally symmetrical, exce pt 2 cases of hemorrhage and 1 of low density . 3. Of all 28 cases of the low densities, 15 cases(53.6%) were located in the globus pallidus, 10(35.7%) in the cerebral white matter and 3( 1 0.7%) in both of them. 4. Of all 13 cases of the low density lesions in the cerebral wh ite matter, common locations were in the frontal and parietal lobes (65.6%), and more in frontal (40.6%). 5. Of all 13 cases of low density lesions in the cerebral white matter, cases of involving all of the lobes were found in only 4. 6. All of 2 cases of the cal c ified lesions were seen at both sides of the globus pallidus, symmetrically. 7. All of 2 cases of the hemorrhage were seen at thalamus, ventricles and head of caudate nucleus, and these locations were different from those of the low densities or calcifications.
Anoxia ; Brain ; Carbon Monoxide Poisoning ; Carbon Monoxide ; Carbon ; Caudate Nucleus ; Globus Pallidus ; Head ; Heart ; Hemorrhage ; Parietal Lobe ; Thalamus ; Tomography, X-Ray Computed ; White Matter

Intracranial tuberculomas have been reported occasionally, especially in Asia, though much decreased in recentyears. Those lesions can be diagnosed more easily and acurately using CT than conventional method, including angiography. Authors analysed CT findings of 21 cases, confirmed as tuberculoma, at Hanyang University Hospital from May 1979 to June 1983. The resuslts were as follows; 1. Of all 21 cases, multiple lesions were seen in 14 cases (67%) and single in 7(33%). 2. Of all 21 cases, lesions located only at supratentorial were in 19 cases(90%) and remained 2(10%) had lesions at both supra and infratentorial area. And temporal and parietal lobes were common location (65%) of all lesions. 3. In precontrast scan, density of tuberculoma showed largely isodense (68%)and others were slight high (29%) and low(3%). 4. All lesions were enhanced showed as homogeneous nodular (68%),ring-shaped(29%) and target shaped(3%). 5. All rings were continuous and thickness was largely uniform(67%), anddensity of center of the ring was mainly low(67%). 6. Edema was seen in 58% of all lesions: comparing with thesize of tuberculoma, edema size was smaller in 50%, lager in 33% and almost the same in 17%.
Angiography ; Asia ; Edema ; Methods ; Parietal Lobe ; Tuberculoma ; Tuberculoma, Intracranial

Dyschromatosis universalis hereditaria is a rare pigmentary disorder initially described in the Japanese literature. The pattern of inheritance is believed to be autosomal dominant, but many sporadic cases have been reported. We encountered a family in which dyschromatosis universalis hereditaria occurred in seventeen members of three generations. In the two members whom we observed, typical skin lesions were distributed all over the body except palrns and soles. By pedigree analysis, we found an autosomal dominant pattern of inheritance. The differential diagnosis of the other reticulate pigmentary disorders is discussed with a review of dyschromatosis reported in the Korean literature.
Asian Continental Ancestry Group ; Diagnosis, Differential ; Family Characteristics ; Humans ; Pedigree ; Skin ; Wills

No abstract available.
Child* ; Humans ; Staphylococcus aureus* ; Staphylococcus*