1.Analysis of 1262 cases with fractures caused by earthquake injury
Yufeng LI ; Youjun CHANG ; Pan LIU ; Yulong YANG ; Fuqiong PAN
Chinese Journal of Physical Medicine and Rehabilitation 2008;30(12):808-810
Objective To investigate the epidemiological features of fractures caused by earthquake to elevate the quality of prevention and treatment and reduce the mortality and disability rate.Methods A retrospectire study was performed on the data of 1 262 patients with fractures caused by earthquake from May 12,2008 to Aug 31,2008.The following data was statistically analyzed:cause of injury,injured part,associated injuries and treatment.Resultsof the 1 262 cases,11 resulted in deaths;bruise and crush trauma was the major cause (93.98%)of casualties;fractures oflimbs were the main types(55.7%)of fracture;operation was the major treatment.Concluslon Correct treatment is important for fractures caused by earthquake to reduce mortality and disability rate.
2.Analysis of epidemiology and clinical characteristics of 208 diabetic foot patients
Baocheng CHANG ; Congqing PAN ; Shufan ZENG
Chinese Journal of Diabetes 2005;13(2):129-130
Corresponding author:PAN Cong-qing,E-mail:cq.pan@163.com Objective The prevalence of diabetic foot was 2.3% for out-patients and 8.6% (208/2428) for in-patients with amputation rate of 17.3% in our hospital from May 1997 to Dec 2000, more often seen on right than left extremity and in patients over 50 years old than in the younger.
3.Correlation of peptidylarginine deiminase 4 gene polymorphism and colorectal cancer
Kehua FANG ; Jihong PAN ; Xiaotian CHANG
Journal of International Oncology 2011;38(6):476-479
Objective We aim to investigate the association between peptidylarginine deiminase type 4 (PADl4) and colorectal cancer by genotyping threetag single nucleotide polymorphisms (tagSNP) genetic maker, to explore the role of polymorphism of PAD14 gene in development of colorectal cancer. Methods A case-control study was conducted using TaqMan-PCR methods to analyze the genotypes of three TagSNPs such as rs1886302, rs2477131 and rs1635561 for 515 patients with colorectal cancer and 549 health controls. Results There is significantly different in allelic frequencies and genotype frequencies of rs1886302 between cases and controls (P=0.039 and 0.040,respectively). The OR value of A allele and AA genotype is 0.796 and 0.731,respectively,and A allele may reduce the probability of incidence of colorectal cancer. No association Was found among SNPs of rs2477131 and rs1635561 within intronl and intron 15 in terms of coloretal cancer. Conclusion Rs1886302 on PADI4 might be a susceptible SNP to coloretal cancer.
4.Assessment of tooth bleaching efficacy with spectrophotometer.
Wenhao ZHU ; Chang LIU ; Jie PAN
West China Journal of Stomatology 2014;32(3):259-262
OBJECTIVETo analyze the changes in CIE L*, a*, and b* at cervical, body, and incisal sites after tooth bleaching by using a spectrophotometer.
METHODSSixty-seven intact and healthy maxillary central incisors were in-vestigated. These incisors were darker than A3 according to the Vita Classical shade guide. The CIE tooth shade parameters L*, a*, and b* were simultaneously recorded at three tooth areas (cervical, body, and incisal) with a spectrophotometer before and after tooth bleaching (35%H2O2 coordinating with Beyond whitening accelerator irradiating). The shade dif-ferential (DeltaE) was calculated. ANOVA, paired t-test, and Pearson correlation analysis were used for data analysis.
RESULTSThe efficacy rates of tooth bleaching were satisfactory, with 86.6%, 86.6%, and 85.1% in the cervical, body, and incisal sites, respectively. The average values of DeltaE were 5.09, 4.44, and 4.40 in the cervical, body, and incisal sites. Tooth bleaching significantly increased L* and significantly decreased a* and b* in all tooth areas (P < 0.01). The decreasing range of Deltab* was more than the increasing range of DeltaL* at the cervical site; opposite results were observed at the incisal site. A positive correlation was detected between baseline b* and DeltaE.
CONCLUSIONThe spectrophotometer could objectively evaluate the whitening effect of tooth bleaching at the different tooth sites. The tooth bleaching system (35%H202 coordinating with Beyond whitening accelerator irradiating) exerts powerful bleaching actions in most of the tooth areas investigated. The order of tooth bleaching effectiveness is cervicalbody>incisal. Yellow coloration is decreased mainly at the cervical site, and brightness was increased mostly at theincisal site. The effectiveness of tooth bleaching increases as the baseline b* value increases.
Humans ; Hydrogen Peroxide ; Incisor ; Molar ; Spectrophotometry ; Tooth Bleaching
5.Experimental Study of Shengjiang Powder on Treating Acute Lung Injury
Jiasong CHANG ; Kaifeng WEI ; Yun PAN
Journal of Guangzhou University of Traditional Chinese Medicine 2001;0(01):-
Objective To investigate the therapeutic mechanism of Shengjiang Powder(SP)on acute lung injury.Methods Forty healthy SD male rats were divided into 3 groups randomly: normal group,model group,and SP group.After administration for 6 days,acute lung injury rat models were established by injecting lipopolysaccharide(LPS)into sublingual vein.Lung histological sections were prepared for the detection of NF-?B expression by immmunohistochemistry.The images of the lung histological sections were captured and the average gray values of nucleus of endothelial cells in lung micrangium were measured.Results Compared with the model group,SP could depress the expression of NF-?B in the nucleus of lung microvascular endothelial cells,and statistical difference existed between the two groups(P
6.A RECORD OF MOTOR NERVE ENDINGS OF THE MUSCLE OF TONGUE
Liling CHANG ; Chihkai NI ; Chewchung PAN
Acta Anatomica Sinica 1957;0(04):-
Serial sections of the tongues of rabbits, albino rats, pigs, dogs, frogs, toads andhuman beings have been made to study the motor nerve endings by the silver imprega-tion method of Cajal Faworsky. The end-plates of the muscle of their tongues has its own specific characteristic, thefunctional significance of these motor nerve endings of the muscle of tongues has beendiscussed. In our investigation we have found out three kinds of unusual motor nerve endings:(1) A single motor end plate, located at two adjacent muscle fibers, has a small branchwhich runs to another muscle. (2) An accessory ending, formed by different startingpoints of nerve fiber, has been found in dogs. (3) Triple motor inervation of individualmuscle fiber of the tongues is to be found in human beings.
7.Antioxidant status and products of oxidative stress in colorectal cancer
Dong CHANG ; Yashuang ZHAO ; Hongzhi PAN
Journal of Medical Postgraduates 2003;0(10):-
Objective:Colorectal cancer is related to antioxidative ability and oxidative stress level.The aim of the study was to evaluate the oxidative stress in colorectal cancer patients and to investigate the relationship between oxidative stress and colorectal cancer.Methods:A total of 60 subjects(30 colorectal cancer patients,30 normal healthy controls) were examined in the study and estimated the protein oxidation,DNA damage,lipid peroxidation and antioxidants-vitamin C,vitamin E,glutathione(GSH) and antioxidative enzymes in serum,respectively.Results:Statistically significantly higher values of protein carbonyl and advanced oxidation protein products(AOPP) were observed in colorectal cancer patients(P
8.Study on Relationship between Life Style and Chronic Diseases
Chinese Journal of Prevention and Control of Chronic Diseases 2006;0(06):-
Objective To analyze the relationship between life style and chronic diseases.Method 2 886 people were selected randomly from three districts of Tianjin and surveyed with a questionnaire on their healthy condition and physical examination.2 622 people were taken a diet survey by 3-days foods intakes weighing and 24-hours diet recall,then the relative risk factors between life style and coronary heart disease,cerebrovascular disease,diabetes,hypertension,overweight and obesity were analyzed.Result The standardized prevalence rates of coronary heart disease,cerebrevascular disease,diabetes,hypertension, overweight and obesity of residents were 9.24%,4.33%,6.74%,34.05%,and 42.62%,respectively.The more the intake of energy, the more the risk for people to suffer from overweight and obesity,OR value being 1.00-1.70.With intake of more than 20 g dietary fiber per day,the risk for suffering from overweight and obesity could be reduced,OR value being 0.68.Logistic analysis showed that heavy salty taste could increase the risk for suffering from hypertension by 42%.Watching TV more than 3 hours per day increased the risk for suffering from cerebrovascular disease and diabetes,OR value being 1.802 and 1.703 respectively.Sleep less than 7 hours per day was a dangerous factor for hypertension,coronary heart disease and cerebrovasular disease,OR value being 1.517, 1.833 and 2.041 respectively.Conclusion The life style such as dietary pattern,sedentary occupation and sleep hours have strong connection with chronic diseases,such as hypertension,diabetes etc.Reasonable diet,suitable exercises,reducing sedentary position and increasing sleep hours will be good for health,and also for the prevention and control of chronic diseases.
9.Formula Improving of Chloramphenicol and Ephedrine Nasal Drops
Xiaochun CHANG ; Xifen PAN ; Shuli WANG
China Pharmacy 2005;0(23):-
OBJECTIVE:To optimize the ratio of glycerol in Chloramphenicol and Ephedrine Nasal Drops included in China's Hospitals Agents Norms.METHODS:By formula optimization and observation on clinical trials,the ratio of glycerol in Chloramphenicol and Ephedrine Nasal Drops was reduced from 300mL to 50mL.RESULTS & CONCLUSION:The Chloramphenicol and Ephedrine Nose Drops prepared in an optimized ratio of glycerol is of much less irritability,good transparency,good compliance in patients,more reliable efficacy,thus deserving to be popularized.
10.Exploration of the safety of percutaneous puncture drainage for liver abscess in patients with blood coagulation dysfunction
Tao PAN ; Zhihui CHANG ; Zhaoyu LIU
Journal of Interventional Radiology 2015;(7):602-604
Objective To discuss the safety of percutaneous puncture drainage for liver abscess in patients with blood coagulation dysfunction. Methods A total of 85 patients with liver abscess, who were admitted to authors’ hospital during the period from January 2013 to January 2014 to receive ultrasound-guided percutaneous puncture drainage, were included in this study. According to the international normalized ratio of prothrombin time≥1.5 and platelet count≤50 ×109/L, the patients were divided into group A (normal coagulation group,n=67) and group B (coagulation dysfunction group,n=18). The occurrence of postoperative complications was recorded and the results were compared between the two groups. Results In both groups, no statistically significant difference in hemoglobin level existed between preoperative level and postoperative one, and no bleeding complications occurred in all patients after the procedure. Conclusion For patients with liver abscess complicated by blood coagulation dysfunction, percutaneous puncture drainage treatment is safe and reliable.