1.Significance of IgG and IgM antibodies in the diagnosis of scrub typhus and evaluation of rickettsia tsutsugamushi strain Boryong as a diagnostic antigen.
Woo Hyun CHANG ; Sun Ho KEE ; Mu Jin CHU ; Myong Sik CHOI ; Ik Sang KIM
Journal of the Korean Society for Microbiology 1992;27(1):19-27
No abstract available.
Antibodies*
;
Chungcheongnam-do*
;
Diagnosis*
;
Immunoglobulin G*
;
Immunoglobulin M*
;
Orientia tsutsugamushi*
;
Rickettsia*
;
Scrub Typhus*
2.Significance of IgG and IgM antibodies in the diagnosis of scrub typhus and evaluation of rickettsia tsutsugamushi strain Boryong as a diagnostic antigen.
Woo Hyun CHANG ; Sun Ho KEE ; Mu Jin CHU ; Myong Sik CHOI ; Ik Sang KIM
Journal of the Korean Society for Microbiology 1992;27(1):19-27
No abstract available.
Antibodies*
;
Chungcheongnam-do*
;
Diagnosis*
;
Immunoglobulin G*
;
Immunoglobulin M*
;
Orientia tsutsugamushi*
;
Rickettsia*
;
Scrub Typhus*
3.An Analysis of Early Complications after Percutaneous Vertebroplasty in Elderly People.
Chang Myong CHOI ; Young Mi HAN ; Sang Ho LEE
Journal of the Korean Geriatrics Society 2000;4(1):76-81
With the growing interests in the treatment of osteoporosis. percutaneous Vertebroplasty aimed at stabilizing and preventing progressiv eosteoporotic vertebral compression fracture has been tried. We analyzed 60 cases of vertebroplasty for senile osteporotic vertebvral compression fractures performed from April to August, 1999 at Wooridul Spine Hospital. We observed dramatic pain relief in almost cases within 6~72 hours(mean, 36 hours). Mean value of the Visual Analogue Scale(VAS) decreased from 8.3 to 2.8 after the procudure. The Operative complications were as follows ; epidural leakage(70 levels). Paraparesis(2 cases), Paravertebral venous leakage, Intradiscal leakage, foraminal leakage transient hypotension and transient apnea. This procedure is relatively safe and effective treatment modality for osteoporotic compression fracture. But much attention is required in selection of the cases such as severe crushing fracture, suspicions cortical fracture of the endplate and bursting fracture. The viscosity of the material and avoidance of rapid injection were important in preventing complications.
Aged*
;
Apnea
;
Fractures, Compression
;
Humans
;
Hypotension
;
Osteoporosis
;
Spine
;
Vertebroplasty*
;
Viscosity
4.Correlation Analysis between Ocular Surface Parameters with Subjective Symptom Severity in Dry Eye Disease
Jee Hye LEE ; Chang Hwan KIM ; Chul Myong CHOE ; Tae Hoon CHOI
Korean Journal of Ophthalmology 2020;34(3):203-209
Purpose:
To evaluate the clinical symptoms of patients with dry eyes, based on the ocular surface disease index (OSDI) and analyze the relationship between OSDI and various ocular surface parameters.
Methods:
This was a retrospective study that included 45 eyes of 45 dry eye patients who visited the Seoul Nune Eye Hospital from August 2017 to December 2017. The patients were assessed by non-invasive keratography for the first break-up time, lipid layer thickness (LLT), tear osmolarity, tear matrix metalloproteinase-9 immunoassay as well as with the conventional Schirmer I test and fluorescein break-up time. The patient’s symptoms were evaluated by the OSDI questionnaires and correlations were analyzed based on the parameters described above.
Results:
There were significant negative correlations between OSDI and non-invasive keratography for the first break-up time (p = 0.038, r = -0.330), and LLT (p = 0.005, r = -0.426). However, there were no significant correlations between OSDI and fluorescein break-up time, Schirmer I score, and tear osmolarity (p = 0.173, 0.575, and 0.844 respectively). OSDI was not significantly different between matrix metalloproteinase-9 positive and negative groups (p = 0.768).
Conclusions
Non-invasive examinations such as non-invasive keratograph break-up time and interferometry of LLT can be efficient tools for evaluating dry eye symptoms.
5.Acute Effects of Paroxetine and Amitriptyline on the Psychomotor Performancein Healthy Volunteers.
Chang Yoon KIM ; Myong Ki CHOI ; Chang Hwa LEE ; Joon Ho AHN ; Chul LEE ; Oh Su HAN
Journal of Korean Neuropsychiatric Association 1999;38(6):1469-1478
OBJECTIVES: Paroxetine is known to have fewer cognitive side effects than older antidepressants such as amitriptyline. To confirm this objectively, we compared the effects of paroxetine on the psychomotor performance with those of amitriptyline in 10 healthy volunteers. METHOD: Paroxetine and amitriptyline were administered orally in a double-blind, two-way, single dose, crossover design. Assessments of psychomotor performances were carried out before and 2 and 6 hours after administration of single dose of paroxetine (40mg) or amitriptyline (50mg). Each treatment day was separated by 1 week of washout period. The psychomotor performances were measured using Vienna Determination Unit, Vienna Reaction Time, Vienna Signal Detection, Grooved Pegboard Test and Finger Tapping Test. The data were analyzed using two-way, repeated measures ANOVA on a crossover model. RESULTS: The results showed that paroxetine 40mg produced no significant performance decrements on the every test of psychomotor performances, whereas amitriptyline 50mg produced markedly impaired performance on most of the psychomotor tests. CONCLUSION: This study confirmed pervious findings that paroxetine is generally devoid of adverse side effects on psychomotor performance.
Amitriptyline*
;
Antidepressive Agents
;
Cross-Over Studies
;
Fingers
;
Healthy Volunteers*
;
Paroxetine*
;
Psychomotor Performance
;
Reaction Time
6.Learning Curve Associated with Complications in Biportal Endoscopic Spinal Surgery: Challenges and Strategies.
Dae Jung CHOI ; Chang Myong CHOI ; Je Tea JUNG ; Sang Jin LEE ; Yong Sang KIM
Asian Spine Journal 2016;10(4):624-629
STUDY DESIGN: Descriptions of technical strategies to overcome pitfalls associated with early learning periods in biportal endoscopic spinal surgery (BESS). PURPOSE: To introduce BESS for lumbar spinal diseases (LSDs) and to inform certain challenges to be overcome in mastering the technique. OVERVIEW OF LITERATURE: BESS has shown superior benefits including excellent magnification, a wider range of view by dynamic handling of an endoscope and instruments. Clinical reports, however, have not yet been very revealing for its new introduction into minimally invasive spine surgery. METHODS: To evaluate the learning curve for BESS, the procedures for various LSDs by one surgeon were analyzed in the view of shortening of the operating times and reduction of complications. Reviewing of recorded procedures helped in finding the reasons and the implemented solutions. RESULTS: The 68 cases included 25 for lumbar disc herniation (LDH), 3 for revision for recurred LDH, 39 for lumbar spinal stenosis (LSS) and 1 for synovial cyst. The operation time for the total cases averaged 83.7±33.6 minutes. According to diagnosis, it was 68.2±23.7 minutes for LDH. After the 14th case of LDH, it was nearly constant and close to the average time. One level of LSS needed 110.4±34.4 minutes. Prolonged operation times even in some later cases of LSS were mainly from struggling against blurred vision due to epidural bleeding. There were 7 cases of complications (10.3%) including 2 cases of dural tear, 1 case of root injury, and 4 cases of incomplete decompression on postoperative magnetic resonance imaging. There was no case of symptomatic hematoma or wound infection. CONCLUSIONS: BESS seemed to have a relatively short learning curve period. The overall complication rate in early learning period was 10.3%. These could be avoided by magnified regional views on an endoscope and a clear surgical field by controlling epidural bleeding.
Decompression
;
Diagnosis
;
Endoscopes
;
Hematoma
;
Hemorrhage
;
Learning Curve*
;
Learning*
;
Lysergic Acid Diethylamide
;
Magnetic Resonance Imaging
;
Spinal Diseases
;
Spinal Stenosis
;
Spine
;
Synovial Cyst
;
Tears
;
Wound Infection
7.Effect of 3% Diquafosol Tetrasodium on Tear Film Stability after Laser-assisted in situ Keratomileusis
Chang Hwan KIM ; San SEONG ; Jong Ku KIM ; Jae Ho CHOI ; Chul Myong CHOE ; Tae Hoon CHOI ; Sekyung KIM
Journal of the Korean Ophthalmological Society 2019;60(10):915-921
PURPOSE: To evaluate the efficacy of 3% diquafosol tetrasodium (DQ) after laser-assisted in-situ keratomileusis (LASIK). METHODS: This prospective randomized study included 150 eyes in 75 patients who were scheduled for LASIK. The patients in the 3% diquafosol tetrasodium (DQ) group (37 patients, 74 eyes) were instructed to apply one drop of DQ, six times daily post-op, while the patients in the 0.3% sodium hyaluronate (HA) group (38 patients, 76 eyes) were instructed to apply one drop of HA, six times daily post-op. A Schirmer test, tear film break-up time (BUT), corneal and conjunctival fluorescein staining score (FLSS), and ocular surface disease index (OSDI) were evaluated pre-op and at 1, 4, and 12 weeks post-op while the tear osmolarity was evaluated pre-op and at 4 and 12 weeks post-op. RESULTS: There was no significant difference between the two groups regarding Schirmer test results or tear osmolarity and conjunctival FLSS. The BUT was significantly higher in the DQ group at 1 week and 12 weeks post-op. The corneal FLSS was significantly lower in the DQ group at 1 week, 4 weeks and 12 weeks post-op. The OSDI was significantly lower in the DQ group at 1 week post-op. CONCLUSIONS: Use of 3% diquafosol tetrasodium after surgery improved ocular dryness and increased the tear film stability.
Fluorescein
;
Humans
;
Hyaluronic Acid
;
Keratomileusis, Laser In Situ
;
Osmolar Concentration
;
Prospective Studies
;
Tears
8.An Occult Fracture in a Ankylosing Spondylitis Patient.
Chang Myong CHOI ; Ji Ho YANG ; Il Woo LEE ; Chul Ku JUNG ; Joon Ki KANG
Journal of Korean Neurosurgical Society 1997;26(1):146-151
A61-year-old head-injured patient exhibited acute onset of paraplegia during hospital in-care. Review of radiographs showed an occult linear transverse fracture line between the T11 and T12 vertebrae. An MRI scan performed after paraplegia showed compression of the spinal cord by a bony fragment. This case report presents a rare but devastating complication of an occult fracture at the T-L junction in patient with ankylosing spondylitis which was considered less significant due to more severe head injury. Thorough clinical and roentgenographic examination of the entire vertebral column is recommended in patients with ankylosing spondylitis who have sustained injury. Even if minor spinal trauma occurs in such clinical setting, the condition should be managed as a spinal fracture with potentially serious neurologic complications.
Craniocerebral Trauma
;
Fractures, Closed*
;
Humans
;
Magnetic Resonance Imaging
;
Paraplegia
;
Spinal Cord
;
Spinal Fractures
;
Spine
;
Spondylitis, Ankylosing*
9.Factors Affecting Preparation Stage to Quit Smoking in Men.
Jeong Woon YEON ; Hyeongsu KIM ; Kunsei LEE ; Sounghoon CHANG ; Heejung CHOI ; Eunmi HAM ; Jun Pyo MYONG
Journal of Korean Academy of Nursing 2012;42(3):377-384
PURPOSE: This study was done to investigate factors affecting preparation stage to quit smoking in men. METHODS: Based on data from the Community Health Survey conducted in Chungbuk Province in 2008, we estimated rates and odds ratio (OR) of smoking cessation intention for 2,639 men who were current smokers. Multivariate logistic regression analyses were used to identify factors affecting preparation stage to quit smoking. RESULTS: Among current male smokers, the rate of smoking cessation intention was 17.1%. The OR of factors affecting smoking cessation was as follows: Compared to men with middle school education, the OR for rate of smoking cessation intention in men with high school education was 1.47 (p=.018), and for college or higher, 1.55 (p=.017). Compared to being single, the OR for cohabitation after marriage was 1.61 (p=.011) and living alone after marriage, 2.23 (p=.005). The OR for attempt to quit smoking, exposure to secondhand smoke and participation in smoking education were 6.80 (p<.001), 1.32 (p=.020) and 1.69 (p=.005), respectively. CONCLUSION: Results of this study show that it is necessary to decrease exposure to secondhand smoke and to increase participation in smoking cessation education targeting current smokers to move them from precontemplation or contemplation stage to preparation stage.
Adult
;
Age Factors
;
Aged
;
Demography
;
Humans
;
Logistic Models
;
Male
;
Marriage
;
Middle Aged
;
Odds Ratio
;
Smoking/*psychology
;
*Smoking Cessation
;
Tobacco Smoke Pollution
;
Young Adult
10.Comparison of polar maps of dipyridamole stress/rest MIBI myocardial SPECT and coronary angiography in coronary disease.
Myung Chul LEE ; Dong Soo LEE ; Myung Yong LEE ; Chang Woon CHOI ; Dae Won SOHN ; June Key CHUNG ; Myong Mook LEE ; Young Bae PARK ; Jung Don SEO ; Young Woo LEE ; Chang Soon KOH
Korean Journal of Nuclear Medicine 1993;27(1):51-58
No abstract available.
Coronary Angiography*
;
Coronary Disease*
;
Dipyridamole*
;
Tomography, Emission-Computed, Single-Photon*