1.Determinants of Marital Satisfaction among a Commercial Cockpit Crew Member.
Yong Ho LEE ; Chang Kyo SHIM ; Yoo Kyung JUNG
Korean Journal of Aerospace and Environmental Medicine 2000;10(3):227-234
INTRODUCTION: The purpose of this study is to define the attributable factors related to the marital satisfaction of the professional airmen working for a commercial airlines. METHODS: Data was collected from the all professional civil airline pilots by using self-administrative questionnaire during the three months(2000. 1. 3 - 3. 31). The response rate was 95.2%(472). RESULTS: First, there were statistically significant differences in marital satisfaction by type of religion, in sexual satisfaction by type of housing, work duration, and flying hours. However, there were no significant variables in communication. Second, communication, sexual satisfaction, and number of female kids, and work duration were significantly correlated to marital satisfaction. There was significant correlation between sexual satisfaction and communication, marital years, and work duration. There was also statistical correlation among marital years, number of male kids, female kids, and total number of kids, work duration, and flying hours. Third, communication was the most significant attributable variable, and following sexual satisfaction related to marital satisfaction. CONCLUSION: It is intended that these finding will contribute to assisting the social work practices. It is necessary for the aircrew to develop communication skill to provide a happy marital life. Future research needs to study various methods and psychosocial factors involving quality of marital life for the Korean aircrew.
Diptera
;
Female
;
Housing
;
Humans
;
Male
;
Psychology
;
Social Work
;
Surveys and Questionnaires
2.Argyrophilic Nucleolar Organizer Region and Expression of Ki-67 in Malignant Lymphoma.
Hee Jung LEE ; An Hi LEE ; Kyo Young LEE ; Chang Suk KANG ; Sang In SHIM ; Byung Kee KIM
Korean Journal of Pathology 2000;34(4):257-263
Nucleolar organizer regions (NORs) are loops of DNA which occur in the nucleoli of cells which possess ribosomal RNA genes. The numbers and areas of NORs have been thought to be related to cellular activities. We aimed to investigate the direct relationship between the parameters of AgNORs and cellular proliferative activity using immunohistochemical method with the monoclonal antibody Ki-67, which demonstrates proliferating nuclei. The sequential technique for the simultaneous Ki-67 immunostaining and NOR staining was applied to the same slides of a series of non-Hodgkin's lymphomas (NHL) of the low, intermediate, and high grade type. The number of AgNOR per cell was counted and mean NOR percentage nuclear area (NPNA) was measured by morphometry in both the Ki-67 positive and Ki-67 negative nuclei. The increased immunoreactivity for Ki-67 was found in the high grade than in the low grade non-Hodgkin's lymphoma. This was reflected in the two areas of the palatine tonsils and lymph nodes, the positive cell counts being higher in the follicle center nuclei than in those in the interfollicular compartment. In general the numbers and NPNA of AgNORs were higher in the Ki-67 positive nuclei than in those lacking the antigen in malignant lymphomas as well as in control. The AgNORs numbers and NPNA in controls were the highest in the Ki-67 positive cells in the follicular area and the lowest in the Ki-67 negative cells in the perifollicular area. In malignant lymphomas the numbers and NPNA of AgNORs tended to increase in proportion to their grade in both the Ki-67 positive and negative cells. The numbers of AgNORs of the high grade and the NPNA of the intermediate and the high grade were significantly higher in Ki-67 positive cells than in Ki-67 negative ones. With this double staining method it was now possible to confirm that numbers and NPNA of AgNORs were directly related to the cellular proliferative activity. In maligant lymphoma, among the several parameters of the AgNORs, NPNA in Ki-67 positive cells is proposed to be the most useful marker in determining the prognosis of the patient.
Cell Count
;
DNA
;
Genes, rRNA
;
Humans
;
Lymph Nodes
;
Lymphoma*
;
Lymphoma, Non-Hodgkin
;
Nucleolus Organizer Region*
;
Palatine Tonsil
;
Prognosis
3.Paneth Cell-rich Carcinoma of the Stomach: A case report .
Ah Won LEE ; Young Shin KIM ; Kyo Young LEE ; Chang Suk KANG ; Sang In SHIM
Korean Journal of Pathology 1998;32(8):613-615
Paneth cell-rich carcinoma is essentially an adenocarcinoma with a predominance of Paneth cells. A 60-year-old male patient was admitted with a history of abdominal distension for several months. Endoscopic examination revealed a large ulceroinfiltrative tumor involving most of the areas of the stomach. The biopsy of the lesion confirmed poorly differentiated adenocarcinoma and total gastrectomy was followed. The submitted total stomach contained a diffuse infiltrative Borrmann type IV mass with ulceration, 8.0 3.5 cm, at the body along the lesser curvature. Microscopically, it was composed of Paneth cell differentiated cancer cells and poorly differentiated tubular adenocarcinoma cells. The Paneth cell differentiation was characterized by cytoplasmic coarse eosinophilic granules, which were PAS-positive and positive reaction for lysozyme. Electron microscopic examination showed numerous, spherical, electron-dense, homogeneous granules corresponding to those in Paneth cells as well as mucin granules in the signet-ring cells, and various intermediate forms in some cancer cells, which might be immature in the Paneth cell lineage.
Adenocarcinoma
;
Biopsy
;
Cell Differentiation
;
Cell Lineage
;
Cytoplasm
;
Eosinophils
;
Gastrectomy
;
Humans
;
Male
;
Middle Aged
;
Mucins
;
Muramidase
;
Paneth Cells
;
Stomach*
;
Ulcer
4.Expression of the nm23 and E-cadherin Proteins in Breast Carcinoma.
Jean a KIM ; Won Il KIM ; Sang In SHIM ; Chang Suck KANG ; Kyo Young LEE ; Young Shin KIM
Korean Journal of Pathology 1998;32(1):29-34
Expression of the nm23 and E-cadherin proteins has been studied in a number of tumors. Reduced expression of the nm23 and E-cadherin proteins seems to be associated with metastasis or disease progression in some tumors, including breast carcinoma. To assess the role of nm23 and E-cadherin in tumor differentiation and metastasis of breast carcinoma, immunohistochemical staining for the nm23 and E-cadherin proteins was performed in paraffin embedded tumor samples from 86 breast carcinomas. The results were as follows: 1) Expression of the nm23 protein in breast carcinoma was strong positive in 32 cases (37.2%), weak positive in 26 cases (30.2%), and negative in 28 cases (32.6%) of the cases. Expression of the nm23 protein in breast carcinoma decreased according to histological grade and lymph node metastasis, but was not statistically significant. 2) Expression of the E-cadherin protein in breast carcinoma was strong positive in 50 cases (58.1%), weak positive in 24 cases (27.9%), and negative in 12 cases (14%) of the cases. Expression of the E-cadherin protein in breast carcinoma decreased according to histological grade and lymph node metastasis, but was not statistically significant. 3) There was a statistically significant correlation between the expression of the nm23 protein and the E-cadherin protein in breast carcinoma (p<0.05). These results suggest that the expression of the nm23 and E-cadherin proteins is related to tumor differentiation, and may also be an useful prognostic factor in breast carcinoma.
Breast Neoplasms*
;
Breast*
;
Cadherins*
;
Disease Progression
;
Lymph Nodes
;
Neoplasm Metastasis
;
Paraffin
5.Congenital Intracranial Teratoma with Extension into Oral Cavity: An autopsy case.
Young Sill KIM ; Kyo Young LEE ; Chang Suck KANG ; Sang In SHIM ; Sun Moo KIM
Korean Journal of Pathology 1990;24(3):326-330
Intracranial teratomas which were first described by Maier in 1861 are uncommon. Those presenting at birth are very rare and in our knowledge no case has been reported in Korea. In November, 1988, we experience a case of congenital intracrainal teratoma which replaced almost all cerebral tissue, filled out the oral cavity, and was protruded from the mouth. A female fetus was artificially delivered by a 25-year-old primigravida at 22 weeks of gestation, because of marked hydramnios and fetal hydrocephalus which were detected by prenatal ultrasonography. Microscopically, tissues from all three germ layers, including a lot of neuroepithelim and primitive mesenchymal tissue, were shown. A brief review of the literature was done.
Female
;
Humans
6.Mucous Gland Adenoma of the Bronchus; Light Microscopic and Ultrastructural Features.
Mi Seon KWON ; Kyo Young LEE ; Young Shin KIM ; Chang Suk KANG ; Sang In SHIM
Korean Journal of Pathology 1997;31(9):898-901
We present a case of mucous gland adenoma arising from the main bronchus of the lower lobe of the left lung in terms of clinicopathologic, immunohistochemical, and ultrastructural aspects as well as review of related literatures. The patient, a 31-year-old female, was admitted to Catholic University Medical College Hospital with complaints of coughing and purulent sputum for about seven years. The chest CT showed a severely calcified tumor in the left lower lobe of the lung. Grossly, the calcified tumor arising from the main bronchus protruded into the lumen and showed bronchiectasis of the lower lobe and atelectasis of the upper lobe of the lung. The tumor was pale brown-gray and sharply circumscribed and showed some small cystic spaces filled with mucoid material. Microscopically, most of the tumor showed dystrophic calcification. The growth pattern of the tumor is composed of cysts, tubules, and glands lined by cytologically bland columnar, cuboidal, or flattened mucus secreting cells. Electron micrograph of tumor cells showed some round or oval mucous granules measuring 0.5-1.8 micrometer.
Adenoma*
;
Adult
;
Bronchi*
;
Bronchiectasis
;
Cough
;
Female
;
Humans
;
Lung
;
Mucus
;
Pulmonary Atelectasis
;
Sputum
;
Tomography, X-Ray Computed
7.Strumal Carcinoid of the Ovary: Report of a case.
Su Kyeong YEON ; Kyo Yeong LEE ; Chang Seog KANG ; Sang In SHIM ; Sun Moo KIM
Korean Journal of Pathology 1993;27(2):187-190
Strumal carcinoma of the ovary is rare tumor of germ cell origin characterized by intimate mixture of thyroid tissue and carcinoid. We report a strumal carcinoid tumor associated with ipsilateral follicular cyst and contralateral mature cystic teratoma of the ovary in a 47-year-old woman. Histologically it was composed largely of trabeculae partly of insular carcinoid and focally of individual thyroid follicles. Many cells in the carcinoid areas and even some follicular areas contained abundant argyrophile granules, and they also, in the corresponding areas, demonstrated thyroglobulin. Electron microscopic findings revealed abundant neurosecretory granules and colloid material in the same cell. We agree that this tumor is derived from hybrid showing thyroid and neuroendocrine differenciation.
Female
;
Humans
;
Cysts
8.Renal Cell Carcinoma Associated with Rhabdomyosarcomatous Component: Report of a case.
Mee Soo CHANG ; Mi Kyung JEE ; Kyo Young LEE ; Sang In SHIM ; Sun Moo KIM
Korean Journal of Pathology 1987;21(1):40-44
Renal cell carcinoma, intimately associated with a sarcomatous component, is a rare malignant renal tumor. There is disagreement whether these represent true sarcomas or are sarcomatoid metaplasia. Therefore, this sarcomatous component is at times still a troublesome problem for pathologists. In March, 1986, we experienced a case of renal cell carcinoma associated with rhabdomyosarcomatous component in 47 year-old woman who had a rapidly enlarged, palpable abdominal mass. Grossly, a spherical renal cell carcinoma, 17x14x10 cm, in upper and middle portions of the right kidney showed extension through the renal capsule into the perirenal fat. Area of myxoid change was evident in the reanl cell carcinoma, with extensive hemorrhagic necrosis. Microscopically, in the myxoid area, there was malignant spindle cell proliferation in which many rhabdomyoblasts showing distinct cross striation could be demonstrated. This rhabdomyosarcomatous component intermixed with renal cell carcinoma of clear cell type could be also identified in the focal area.
Female
;
Humans
9.Dendriform Pulmonary Ossification: A case report.
Chan Kwon JUNG ; Kyo Young LEE ; Chang Suk KANG ; Sang In SHIM ; Byung Kee KIM
Korean Journal of Pathology 2000;34(11):950-952
The dendriform pulmonary ossification (DPO) is a rare condition of unknown origin in which branching mature bony spicules, usually containing marrow, are found within the alveolar septa. DPO manifests slow progression over many years or may remain unchanged; spontaneous regression has not been recorded. Most patients have no symptoms directly attributed to the ossification, although they may have symptoms due to the underlying fibrotic process. We experienced a case of DPO in 38 year-old-man who presented with cough and sputum for a month. The chest X-ray showed marked coarsened interstitial lung markings in both lungs, especially in the lower lobes. Open lung biopsy was done. Grossly, there were significant dendriform osseous structures. Histologically, branching arrays of mature bone were found in the interstitium and occasionally in alveolar spaces. Some bony trabeculae contained fatty or cellular marrow. The alveolar septa showed fibrous thickening with chronic inflammation. The transition between fibrosis and bone tissue was observed. Our case suggests that dendriform pulmonary ossification may be a rare special manifestation of chronic fibrosing interstitial inflammation of the lung. Osseous structures seem to derive from metaplastic bone formation in the vicinity of undergoing fibrous process.
Biopsy
;
Bone and Bones
;
Bone Marrow
;
Cough
;
Fibrosis
;
Humans
;
Inflammation
;
Lung
;
Lung Diseases, Interstitial
;
Osteogenesis
;
Sputum
;
Thorax
10.Myofibrosarcoma of the Breast: A case report .
Chan Kwon JUNG ; Kyo Young LEE ; Chang Suk KANG ; Sang In SHIM ; Byung Kee KIM
Korean Journal of Pathology 2000;34(1):96-98
Myofibrosarcoma of the breast is a rare malignant mesenchymal tumor that has been reported in only four well documented cases so far. We report a case of myofibrosarcoma of the breast in an 88-year-old man who complained of a palpable mass for 1 year. Microscopically, the tumor consisted mainly of spindled cells, arranged in irregular fascicles and embedded in broad bands of dense hyalinized collagen. It showed ill-defined border infiltrating the adjacent adipose tissue, moderate cellular pleomorphism, and high mitotic rate (8~9/10 HPF). Immunohistochemical study confirmed myofibroblastic differentiation of the tumor cells with diffuse strong reaction for vimentin, smooth muscle actin, and fibronectin.
Actins
;
Adipose Tissue
;
Aged, 80 and over
;
Breast*
;
Collagen
;
Fibronectins
;
Humans
;
Hyalin
;
Muscle, Smooth
;
Myofibroblasts
;
Vimentin