Obsessive-compulsive disorder(OCD) is characterized by recurrent obsessions or compulsions causing marked distress. The lifetime prevalence of OCD in general population is estimated about 2~3%. OCD can usually be distinguished from psychosis by the facts that the patients recognize the irrational nature of the symptoms. OCD is also different from obsessive-compulsive personality in that the patients suffer from obsessions and compulsions which accompany marked distress. The etiology of OCD is not know yet. However, numerous studies suggest that OCD may be associated with several psychological and neurobiological factors such as functional abnormalities of cortico-striatal circuit and serotonin. Selective serotonin reuptake inhibitors(SSRI) are the first-line drugs for the treatmemt of OCD. Approximately 50~80% of OCD patients improved with these anti-obsessional drugs with average reduction in symptoms between 30~70%. Benefits may not appear for 2 or more weeks. Continuing a medication for more than 10 weeks is required to determine the anti-obsessional efficacy. Maintenance treatment is usually required for more than several months. Cognitive-behavioral therapy also proved to be effective, particularly for patients with prominent compulsions. Therefore, it is a logical choice to combine pharmacotherapy and cognitive-behavioral therapy. For extreme cases electroconvulsive therapy(ECT) or stereotaxic neurosurgery may be considered. However, at present, neurosurgery is recommended only for a few patients who remained severely disabled even after years of sufficient treatments.
Compulsive Personality Disorder ; Drug Therapy ; Humans ; Logic ; Neurosurgery ; Obsessive Behavior ; Obsessive-Compulsive Disorder* ; Prevalence ; Psychotic Disorders ; Serotonin

No abstract available.
Delivery of Health Care*

A Case of fungus corneal ulceration of the left eye was presented. The fungus was classified as a Tricophyton. The eye was treated successfully with Griseofulvin and chymotrypsin.
Chymotrypsin ; Corneal Ulcer* ; Fungi* ; Griseofulvin

No abstract available.
Mucocutaneous Lymph Node Syndrome*

No abstract available.
Lymphatic Diseases*

No abstract available.
Immunization*

No abstract available.

No abstract available.
Methods*

The definition of sudden infant death syndrome(SIDS) is the sudden death of an infant that is unexpected by history and cannot be explained by a full postmortem examination including a review of medical history, investigation of the scene of death, and a complete autopsy. Recently, the possibility of occurrence of SIDS after immunization has been suggested. These speculations raised a public awareness as well as apprehension about immunization. SIDS is rare before 1 month of age, with a peak incidence at 2~4 months of age, and 95% of all cases occur by 6 months of age. There are many epidemiological factors associated with an increase of risk for SIDS, such as prone sleep position, maternal smoking during pregnancy, and inborn errors of metabolism However, immunization, which has recently become an issue in SIDS, has no relation to SIDS. The DTaP vaccine in particular, is given during the peak occurrence age of SIDS, which probably led to such misunderstandings. According to an epidemiological data on SIDS in Korea, the estimated incidence of SIDS in the year 1996 was 0.31 in 1,000 live births (male, 0.33 and female, 0.29) with 216 cases per year. The lower incidence of SIDS in Korea than in the United States, European countries, or Japan is probably due to the lack of a surveillance system and public cognition for SIDS. In the present, without established causes for SIDS, public education about the prevention of SIDS is more important than anything. Also, an efficacious surveillance system for SIDS is essential to prevent and decrease its incidence.
Autopsy ; Cognition ; Death, Sudden ; Diphtheria-Tetanus-acellular Pertussis Vaccines ; Education ; Epidemiology ; Female ; Humans ; Immunization ; Incidence ; Infant ; Japan ; Korea ; Live Birth ; Metabolism, Inborn Errors ; Pregnancy ; Smoke ; Smoking ; Sudden Infant Death* ; United States

The author performed a therapeutic lamellar keratoplasty on January 30, 1958, at 5th ROK Army Hospital, for a 24-year-old korean soldier who had persistent unnown corneal ulcer with neovascularization of the right eye during 5yrs months before operation, the ulcer had resisted to the conservative treatments. Donor cornea was a cadaver material removed 5 hours after death and preserved 19 hours at 4 degrees C, until the cornea was used. A 7 mm triphine, with the guard fixed at 0.6 mm in depth was used. Two months after operation the graft was well heald and was transparant with sligh haxiness except for some thick haziness at the lower pupilmargin to the limbus where it had been deeply ulcerated. the vision improved from perception of hand moving to 0.03 of Landolt chart. There was no evidenc of vascularization or ulceration after 5 month of ovservation.
Cadaver ; Cornea ; Corneal Transplantation ; Corneal Ulcer ; Hand ; Hospitals, Military ; Humans ; Military Personnel ; Tissue Donors ; Transplants ; Ulcer ; Young Adult