The purpose of this study was to assess the effect of basic-fibroblast growth factor (bFGF) on the xenograft for radial bone defect in adult rats. Twenty adult Wistar rats weighing between 200 and 250g were divided into two groups; bFGF group (10 rats, 20 radiuses) and non-bFGF group (10 rats, 20 radiuses). A segmental bone defect measuring 5mm in length was made at both radiuses 10mm proximal to the wrist joint. The defect was filled with xenograft (Lubboc) measuring 3x3x5 mm in size. The xenograft was treated with 400 ng/ml bFGF (recombinant human basic-fibroblast growth factor ) mixed with liquid collagen (Vitrogen 100) in the bFGF group, but with collagen alone in the non- bFGF group. At 6 and 12 weeks after the treatment, the radiuses were harvested and examined histologically and the area of the remained xenograft not replaced by host bone was measured by image analysis system (VIDAS) on mid-sagittal section. The new bone formation and maturation from the differentiation of osteoblast was more remarkable in the bFGF group than in the non-bFGF group. At the time of 6 and 12 weeks after the treatment, the mean of the remained xenograft area was significantly smaller in the bFGF (9.16+/-0.49mm2, 6.20+/-0.30mm2) than in the non-bFGF group (12.16+/-0.59mm2, 10.07+/-0.48mm2) (P<0.001). In comparison with the areas of new bone replacemet area between 6 week and 12 week groups, sigificant and remarkable new bone replacement area could be achieved in the bFGF group than in the non-bFGF group (P<0.05). From these results, it is suggested that bFGF might increase the replacement of xenograft by new host bone and accelerate the healing process for the segmental bone defect of the radius in adult rats.
Adult ; Animals ; Collagen ; Fibroblast Growth Factor 2 ; Heterografts ; Humans ; Osteoblasts ; Osteogenesis ; Radius ; Rats* ; Rats, Wistar ; Wrist Joint

The authors did clinical analysis of 34 cases of suppurative athritis of hip for period of three years from Jan. 1973 to Jan. 1976 at Dept. of Orthopedics, Catholic Medical Center. Through this study following results were obtained. 1. Most of the patients were under the age of 6 years including twenty-six males and eight females. 2. Lag period to treatment in 10 cases was within 3 days, 14 cases within a week: most of these series were treated within a week. 3. Frequent clinical symptom and signs were pain on hip 34 cases, fever 30 cases, limited motion of hip 24 cases and flexion contracture 8 cases. 4. Causative micro-organism was isolated in the cases of diseased hip: Staphylococcus aureus in. 24 cases, β-hemolytic streptococcus in 8, pneumococcus 1, and Gram positive bacillus 1 cases. 5. The laboratory findings included leucocytosis over 15,000 per mm in 31 cases, increased erythrocyte-sedimentation rate 15mm per hour in 33 cases. All the cases were leucocytosis with increased ESR but. 5 were only increased ESR. 6. In authors experience early incision and drainage with specific antibiotics were a choice of treatment in the acute supprative arthritis of hip 7. Result become progressibly less satisfactory in proportion in the length of time after onset at which treatment is started. a) When sufficient time has elapsed for adhesion to develop the pocket to the head thus can not be drained properly by the active movements. Indeed, it is possible, that may be actually harmful in promoting absorption from such pocket. b) In case of long standing erosion of cartilage with denuded bone areas hinder or prevent efficient active movements. c) In case of long duration, blood stream infection is an ever present danger, as well as a aggrevation of existing organic disease by the infective process.
Absorption ; Anti-Bacterial Agents ; Arthritis ; Arthritis, Infectious ; Bacillus ; Cartilage ; Child ; Contracture ; Drainage ; Female ; Fever ; Head ; Hip ; Humans ; Male ; Orthopedics ; Rivers ; Staphylococcus aureus ; Streptococcus ; Streptococcus pneumoniae

No abstract available.
Humans ; Infant*

In the figure 3, designation of severity of bronchopulmonary dysplasia (BPD) was misprinted. Open bars (white) represent severe BPD, not mild BPD. Closed bars (Black) represent mild BPD, not severe BPD. Gray bars in the middle represent moderate BPD without change.

OBJECTIVE: To investigate the preterm labor & preterm infants care in Kwangju and Chonam. METHODS: A study was conducted for 2,360 newborns who were born at four main hospitals in Kwangju and chonam from January 1, 1995 to December 31, 1997. Data were collected by review of hospital records. RESULTS: 1. The survival rate was 6.90% at 23~34 weeks, 38.60% at 27~28weeks and 90.67% after 31wks. 2. The survival rate divided according to birth weight were 8.89% below 1,000gm, 57.14% in 1,001~1,500gm, 86.75% in 1,501~2,000gm and 93.37% over 2,000gm respectively. 3. Clinical causes of neonatal death were RDS(48.84%) hyperbilirubinemia (20.74%), sepsis(11.95%) and pneumonia(9.67%). 4. Incidence of RDS was 23.22% and it's neonatal mortality was 36.28%. CONCLUSION: The survival rate of preterm birth in Kwang-Ju and Chon-nam was still lower than data from advancing countries, and main cause of neonatal death was respiratory distress syndrome.
Birth Weight ; Female ; Gwangju* ; Hospital Records ; Humans ; Hyperbilirubinemia ; Incidence ; Infant ; Infant Mortality ; Infant, Newborn ; Infant, Premature* ; Obstetric Labor, Premature ; Pregnancy ; Premature Birth ; Survival Rate

PURPOSE: The purpose of this study was to identify whether the maternal-fetal attachment is related to choose the rooming-in of postpartum women. METHOD: This is a retrospective descriptive study. The data was collected from April 1 to May 31, 2001. Subjects who had NSVD were 68 mothers who opted the rooming-in and 98 mothers who did not choose the rooming-in at one hospital in Seoul, Korea. The research questionnaire consisted of 14 items on general characteristics, and 24 items on maternal fetal attachment developed by Cranley(1981). RESULT: 1. There was significant statistical difference in general characteristics between rooming-in and non rooming-in groups in prenatal class attendance, and husband attendance during the delivery. 2. There was significantly higher level of maternal fetal attachment score in the rooming-in group. 3. There was higher level of maternal fetal attachment score in the group which had participated in childbirth education than the group which didn't had participated. CONCLUSION: It could be concluded that the maternal fetal attachment is identified as a significant factor choosing the rooming in for postpartum women. Therefore it is needed to increase maternal fetal attachment of pregnant women before making decision for whether they choose the rooming-in or non-rooming in after delivery.
Female ; Humans ; Korea ; Mothers ; Postpartum Period* ; Pregnant Women ; Prenatal Education ; Surveys and Questionnaires ; Retrospective Studies ; Seoul ; Spouses

PURPOSE: The purpose of this study was to identify the influencing factors on postpartum fatigue in the parturient women. METHODS: The data were collected from July to September, 2006 using self-report questionnaires. The sample was 143 healthy parturient women who visited the outpatient clinic at 2 hospitals for a routine follow up after childbirth. The data were analyzed by using SPSS 12.0 Win program. RESULTS: There were significant differences in the postpartum fatigue by age, religion, sleep hour, and complaint of perceived health problem. The postpartum fatigue were significantly correlated with infant care stress(p<0.001), sleep satisfaction(p<0.001), and feeding difficulty(p=0.016). The multiple regression analysis showed that the postpartum fatigue were significantly predicted by the infant care stress, sleep satisfaction and complaint of perceived health problem. These variables explained 31.8% of the variance of postpartum fatigue. The infant care stress was the main predictor of postpartum fatigue. CONCLUSIONS: It could be concluded that the nursing intervention for reducing the infant care stress should be developed to manage the postpartum fatigue for parturient women. Prospective studies are needed to be conducted to verify the causal relationship between infant care stress and postpartum fatigue.
Ambulatory Care Facilities ; Fatigue* ; Female ; Follow-Up Studies ; Humans ; Infant ; Infant Care ; Nursing ; Parturition ; Postpartum Period* ; Surveys and Questionnaires

No abstract available.
Hepacivirus* ; Hepatitis C Antibodies* ; Hepatitis C* ; Hepatitis* ; Prevalence*

Castleman disease is a relatively rare disease of differential diagnostic interest in patients with lymphadenophathy. The etiology and pathogenesis of the Castleman disease are still not elucidated and the MRI findings of disease has not yet been reported. Two patients with Castleman disease studied by MRI are presented: one case presented with a localized anterior mediastinal mass and the other case, with a neck mass. The lesions were characterized by relatively high signal intensities on both T1 and T2 weighted images in both cases, and significant degree of enhancement was seen in the cervical Castleman disease.
Giant Lymph Node Hyperplasia* ; Humans ; Lymph Nodes* ; Magnetic Resonance Imaging* ; Neck ; Rare Diseases

A umbilical omphalomesenteric duct polyp is the result of incomplete closure of the omphalomesenteric duct, which connects the midgut with the yolk sac of the embryo. It may be associated with underlying embryologic anomalies such as Meckels diverticulum and umbilical enteric fistula, the complications of which may at times be fatal. This rare malformation should be clinically discerned from persistent granulation tissue or pyogenic granuloma. Histologically, it shows a polypoid lesion consisting of ectopic gastrointestinal epithelium with the appearance of gastric, intestinal, or colonic mucosa. We report a case of an umbilical omphalomesenteric duct polyp in an 8-year-old male patient, who had had a bright-red polyp on the umbilicus from the age of 1 month and had not had any other types of underlying abnormalities.
Child ; Colon ; Diverticulum ; Embryonic Structures ; Epithelium ; Fistula ; Granulation Tissue ; Granuloma, Pyogenic ; Humans ; Male ; Mucous Membrane ; Polyps* ; Umbilicus ; Vitelline Duct* ; Yolk Sac