2.Antibiotic loaded Plaster of Paris as a Prevention of Experimental Osteomyelitis in Rats
Chang Ju LEE ; Won Ho CHO ; Sung Kee CHANG ; Ho Guen CHANG ; Jae Hong KIM
The Journal of the Korean Orthopaedic Association 1989;24(5):1479-1485
Plaster of Paris is an effective ancillary treatment in the surgery of infected cavities in bone. It is well tolerated and spontaneously absorbed over the period of weeks to months, being replaced by bone of normal architecture. When the antibiotics incorporated into plaster of Paris, the antibiotics are capable of prolonged local release in bactericidal concentrations. Therefore it is proposed that antibiotics loaded plaster of Paris might be a simple adjuvant technique after good surgical debridement for the treatment of bone infection. The authors carried out an experiment to study the effect of plaster of Paris containing antibiotics for a prevention of experimental osteomyelitis, using 45 rats, which were divided into 3 groups. In the Group 1, a defect was made at the proximal metaphysis of the tibia, inoculated by Staphylococcus aureus sensitive to Cephradine and Tobramycin and then filled with plaster of Paris pellet. In the Group 2, a defect was filled with Cephradine loaded plaster of Paris pellet. In the Group 3, a defect was filled with Tobramycin loaded plaster of Paris pellet. Then we observed the healing process of the bone defect in the point of view of the gross findings, radiologic findings and histologic findings at 4th, 8th and 12th week after operation. The results of this study were as follows:l. In the control Group;all 30 cases were infected. 2. In the Group 2;only 4 of 30 cases were infected. 3. In the Group 3;all 30 cases were not infected. 4. The plaster of Paris filled into the defect was absorbed continuously and stimulated the new bone formation.
Animals
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Anti-Bacterial Agents
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Calcium Sulfate
;
Cephradine
;
Debridement
;
Osteogenesis
;
Osteomyelitis
;
Rats
;
Staphylococcus aureus
;
Tibia
;
Tobramycin
3.Clinical investigations of treatment for infected nonunion in long bone with papineau's cancellous bone graft.
Chang Ju LEE ; Won Ho CHO ; Ho Geun CHANG ; Soo Joong CHOI ; Young Ki KIM
The Journal of the Korean Orthopaedic Association 1993;28(1):319-328
No abstract available.
Transplants*
4.Clinical investigation of the children's calcaneus fracture.
Chang Ju LEE ; Won Ho CHO ; Ho Geun CHANG ; Su Jung COI ; Kyung Bum YOO
The Journal of the Korean Orthopaedic Association 1993;28(5):1767-1773
No abstract available.
Calcaneus*
5.An experimental study for calculation of cross sectional area and volume in various objects using auto-CAD(computer aided design).
Chang Ju LEE ; Won Ho CHO ; Ho Guen CHANG ; Su Jung CHOI ; Hyun Cheol YANG
The Journal of the Korean Orthopaedic Association 1991;26(6):1864-1871
No abstract available.
6.Tissue Pressure Changes following Tibia Fracture
Won Ho CHO ; Chang Ju LEE ; Jho Woong KANG ; Ik Yull CHANG ; Hyoung Yong SHIN
The Journal of the Korean Orthopaedic Association 1980;15(3):540-545
Delayed diagnosis of the compartmental syndrome and subsequent delay in performing the fasciotomy can result in needless loss of function and possible amputation of the involved extremity. Unfortunately early evidence of this syndrome is difficult to assess. A direct measurement of the tissue pressure within a closed compartment has been developed which provides physicians with reliable information for determining the need for fasciotomy. In the 27 cases of the tibia fracture, tissue pressure was measured directly by method of the needle manometer in the Department of Orthopedic Surgery, Han Kang Sung Sim Hospital from March, 1979 to August, 1979. The results were as follows: 1. The highest mean tissue pressure per hour was 28 mmHg in anterior compartment at 24 hours after trauma, and 28.4 mmHg in deep post compartment at the same hours. 2. The highest pressure measured in all cases was 38 mmHg in anterior compartment at 24 hours and 39 mmHg in deep posterior compartment at 48 hours after trauma. 3. The return of increased tissue pressure to less than 10 mmHg took 122.6 hours in anterior and 124.4 hours in deep posterior compartment. 4. Tissue pressre was higher when there was associated fibula fracture. 5. Tissue pressure was higher in displaced fractures than in undisplaced fractures. 6. Tissue pressure was higher when fracture was in its upper one-third. 7. Tissue pressure was higher in comminuted fracture than simple fracture.
Amputation
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Delayed Diagnosis
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Extremities
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Fibula
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Fractures, Comminuted
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Methods
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Needles
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Orthopedics
;
Tibia
7.An In-vitro Experimental Study on Antibacerial Effects of Antibiotic-mixed Plaster of Paris Pellets
Sung Kee CHANG ; Chang Ju LEE ; Won Ho CHO ; Young Gun KOH ; Choon Ho LEE
The Journal of the Korean Orthopaedic Association 1987;22(6):1437-1444
Various kinds of bone cements mixed with antibiotics have been widely used for treatment and prevention of infections, especially combined with bone defects. But bone cements have some disadvantages in that they are rather expensive and capable of incurring some complications such ss fibrosis of surrounding soft tissue or local erosion of bone, and furthermore, they must be removed after infection is controlled for bone graft to fill up the defects because they do not have properties of osteoconduction or osteoinduction. So we have come to the idea of using theoretically advantageous plaster of paris to take place of bone cements, and performed in-vitro experiment upon the effectiveness of plaster of paris pellets containing antibiotics, then obtained good results comparable to those from many experimental studies using bone cements. By this, we think that it would be possible in the future to treat and prevent infections supervening bone defects with plaster of paris mixed up with antibiotics. The results are as follows : 1. Sustained release of large amount of antibiotics from plaster of paris enough to exert inhibitory activity on abcterial growth, and there was a direct relationship between concentrations of eluted antibiotics and diameters of inhibitory zones. 2. Tobramycin was capable of inhibiting the growth of S. aureus, E. coli, and Ps. aeruginosa for 7 days at maximum. 3. Cephradine inhibited the growth of S. aureus and E. coli but did not affect that of Ps. aeruginosa. 4. The maximum antibacterial activity wss reached within first 24 hours from the start of elution of antibiotics from plaster of paris.
Anti-Bacterial Agents
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Bone Cements
;
Bone Regeneration
;
Calcium Sulfate
;
Cephradine
;
Fibrosis
;
Tobramycin
;
Transplants
8.Traumatic Bowing of the Ulna with the Dislocation of the Radial Head: Report of a Case
Chang Ju LEE ; Won Ho CHO ; Sung Kee CHANG ; Won Jin CHA
The Journal of the Korean Orthopaedic Association 1988;23(4):1147-1150
Although traumatic bowing of one or both bones of the forearm in children following acute trauma was reported by some authors, traumatic bowing of the ulna with dislocation of the radial head was described by only a few reports. We experienced one case of traumatic bowing of ulna associated with dislocation of the radial head and it was managed with open reduction of the dislocation of radial head and closed management of the bowing of the ulna. The result 1 year 10 months after treatment was very good, so we report this a case with related literatures.
Child
;
Dislocations
;
Forearm
;
Head
;
Humans
;
Ulna
9.Changes of rotator Cuff using Ultrasonography in Frozen Shoulder
Chang Ju LEE ; Won Ho CHO ; Sung Kee CHANG ; In sung LEE ; Joo Ho SHIN
The Journal of the Korean Orthopaedic Association 1989;24(1):156-160
Although several histopathological changes have been developed in frozen shoulder, frozen shoulder is mostly accompanied by the changes of the rotator cuff which has the most important function in movement and has a role in stabilizing the shoulder joint. The changes of the rotator cuff in frozen shoulder have not been reported in Korea yet, but Simon reported that there was an attenuation of the rotator cuff in frozn shoulder. Accordingly, we observed the changes of the rotator cuff in frozen shoulder by ultrasonography, which has no rsdiation exposure and is non-invasive. The authors practiced the shoulder ultrasonography on 36 patients with a pain and limitation of motion in shoulder at the Dept. of Orthopedic Surgery, Hangang Sacred Heart Hospital, Hallym University, from March in 1988 to August in 1988. The results are as follows ;1) Ultrasonography is thought to contribute a great deal in detection of the changes of the rotator cuff, especially of the thickness of the rotstor cuff. 2) Among 36 patients, the thickness of the rotator cuff of 35 patients was 6.494+1.008 mm (M+SD) in the affected shoulder and 6.475+1.052 mm(M+SD) in the unaffected shoulder. In only one pstient, the thickness of the rotator cuff was 1.68+0.58 mm(M+SD) in the affected shoulder and 553+1.16mm(M+SD) in the unaffected shoulder. Theres no significant change in the thickness of the rotator cuff measured by ultrasonography in frozen shoulder. 3) Ultrasonography is an excellent diagnostic method in detecting the rupture of the rotator cuff in frozen shoulder.
Bursitis
;
Heart
;
Humans
;
Korea
;
Methods
;
Orthopedics
;
Rotator Cuff
;
Rupture
;
Shoulder
;
Shoulder Joint
;
Ultrasonography
10.Operative Treatment of the Diaphyseal Fractures of Clavicle (Fresh Fracture and Symptomatic Delayed Union or Nonunion)
Chang Ju LEE ; Won Ho CHO ; Ho Guen CHANG ; Byung Il MIN
The Journal of the Korean Orthopaedic Association 1990;25(1):117-122
All clinical studies reported in the literature have indicated that non-operative treatment is the treatment of choice for the diaphyseal fractures of the clavicle. It has also been suggested by some that open reduction may contribute the development of nonunion. From 1985 to 1989, 23 of 133 diaphyseal fractures of the clavicle were treated by open reduction and internal fixation with the intramedullary pinning with or without cerclage wiring, or prebent plate and screw fixation with supplementary iliac bone graft in each instance. All fractures healed without any complication such as the infection, pin migration, other fixation failure, neurovascular accident, and pseudarthrosis. Based on our experience and review of the literature, we concluded that the indications for open reduction and internal fixation should be: 1. The patient's inability to tolerate prolonged immobilization or recumbency in multiple injury. 2. Widely distracted or displaced fractures in adults. 3. Comminution with one or more large butterfly fragments. 4. Neuro-vascular compromise due to displacement and impingement of the bone fragment. 5. Symptomatic delayed union or nonunion. 6. Refracture. And early operative treatment is safe, reliable and provide excellent results comparable to the conservative treatments.
Adult
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Butterflies
;
Clavicle
;
Humans
;
Immobilization
;
Multiple Trauma
;
Pseudarthrosis
;
Transplants