Childhood granulomatous perioral dermatitis is a distinctive granulomatous process of unknown cause with a benign and self-limited course and no associated systemic manifestations. We herein report a case of a 12-year-old Korean girl with multiple, discrete, monomorphic, flesh-colon, papular eruptions on the perioral, periocular, and perinasal areas of 7-month duration. Histopathologic examination revealed upper dermal and perifollicular granulomatous infiltrate.
Child ; Dermatitis, Perioral* ; Female ; Humans

Diffuse plane xanthoma characteristically presents with asymptomatic, yellow-orange plaques that usually involve periorbital areas, neck, upper trunk and flexural folds. Al-though most cases of diffuse plane xanthoma are associated with multiple myeloma, several cases have been described with different lymphoproliferative disorders and other miscellaneous diseases. We report herein two cases of diffuse plane xanthoma which are not associated with underlying disease.
Lymphoproliferative Disorders ; Multiple Myeloma ; Neck ; Xanthomatosis*

Preoperative diagnosis of heterotopic pregnancy is difficult, especially when ectopic component is chronic and the precise effect of chronic tubal pregnancy on coexisting intra-uterine pregnancy or ongoing pregnancy rates is not known. We present the case of heterotopic pregnancy with a chronic tubal pregnancy incidentally diagnosed during term cesarean delivery in infertile woman conceived after ovulation induction using sequential clomiphene citrate and human menopausal gonadotropin, and timed coitus. Chronic tubal pregnancy might not affect the intrauterine gestation or the mother negatively in non-ruptured cases.
Clomiphene ; Coitus ; Female ; Gonadotropins ; Humans ; Mothers ; Ovulation ; Ovulation Induction ; Pregnancy ; Pregnancy Rate ; Pregnancy, Heterotopic ; Pregnancy, Tubal

Preoperative diagnosis of heterotopic pregnancy is difficult, especially when ectopic component is chronic and the precise effect of chronic tubal pregnancy on coexisting intra-uterine pregnancy or ongoing pregnancy rates is not known. We present the case of heterotopic pregnancy with a chronic tubal pregnancy incidentally diagnosed during term cesarean delivery in infertile woman conceived after ovulation induction using sequential clomiphene citrate and human menopausal gonadotropin, and timed coitus. Chronic tubal pregnancy might not affect the intrauterine gestation or the mother negatively in non-ruptured cases.
Clomiphene ; Coitus ; Female ; Gonadotropins ; Humans ; Mothers ; Ovulation ; Ovulation Induction ; Pregnancy ; Pregnancy Rate ; Pregnancy, Heterotopic ; Pregnancy, Tubal

Indeterminate cell proliferations are rarely described in dermatology literature. Indeterminate cells are characterized by positivity for S-100 protein and CD-la, but are distinguished from Langerhans cells by the absence of Birbeck granules. We present a case of congenital indeterminate cell histiocytoma in a 6-day-old male infant. A Skin examination revealed a solitary, erythematous, 6*6cm, superficially crusted, dome shaped papule on his forehead. A Histopathologic examination showed a dense cellular infiltrate in the dermis, below the atrophic epidermis. Frequently, the nucleus demonstrated a single cleft or crease like the shape of a kidney. These cells showed positivity for S-100 protein. Birbeck granules were not found on electron microscopic examination.
Dermatology ; Dermis ; Epidermis ; Forehead ; Histiocytoma* ; Humans ; Infant ; Kidney ; Langerhans Cells ; Male ; S100 Proteins ; Skin

Lichenoid keratosis (LK), a lichen planus-like keratosis, is a rather frequent skin disorder that has some histological features similar to lichen planus. However, the classification system for LK has not been settled. We report two cases of LK and propose a new classification for LK correlating with clinicohistopathological findings.
Actins* ; Classification ; Keratosis* ; Lichen Planus ; Lichens ; Skin

A 68-year-old Korean woman was consulted to the department of dermatology to evaluate ulcerated lesions on the perianal area, which developed about 3 weeks after a cadaveric renal trans-plantation. Histopathologic examination showed large atypical cytomegalic cells in the upper dermis. Polymerase chain reaction(PCR) study revealed positive cytomegalovirus(CMV) deoxyribonucleic acid(DNA) from the skin tissue. We herein present a case of cutaneous CMV infection presenting as perianal ulcers.
Aged ; Cadaver ; Cytomegalovirus Infections* ; Cytomegalovirus* ; Dermatology ; Dermis ; Female ; Humans ; Kidney Transplantation ; Skin ; Ulcer*

A 57-year-old Korean man with malignant fibrous histiocytoma (MFH) on the leg is presented. Histopathologic examination was consistent with a pleomorphic -storiform subtype of MFH with highly pleomorphic cellular features and frequent mitosis. According to recent evidences, MFH might be a heterogenous group of poorly differentiated tumors rather than a distinct entity. Our case was only positive to CD68 and vimentin immunohistochemically.
Histiocytoma, Malignant Fibrous* ; Humans ; Leg ; Middle Aged ; Mitosis ; Vimentin

Churg-Strauss syndrome (CSS) is a very rare disease which combines the features of asthma, hypereosinophilia, multisystem necrotizing vasculitis and extravascular granuolma. To our knolwedge, there have been four reports in Korean journals, but none in dermatology journals. We report a 37-year-old male who had allergic rhinitis, pansinusitis, a history of atopic dermatitis, multiple prurigo-nodularis like skin lesions, non-fixed interstitial lung in-filtration, hypereosinophilia and subclinical asthma. Clinical and histopathological features of his skin lesions were nonspecific where perivascular lymphocytic infiltration and mild lymphocytic vasculitis were shown. The presence of a pituitary mass and proximal myopathy as op-posed to peripheral neuropathy have not been reported in previous reports of CSS. However, other features of our patient met the criteria of CSS.
Adult ; Asthma ; Churg-Strauss Syndrome* ; Dermatitis, Atopic ; Dermatology ; Humans ; Lung ; Male ; Muscular Diseases ; Peripheral Nervous System Diseases ; Rare Diseases ; Rhinitis, Allergic ; Skin ; Vasculitis

Plexiform neurilemmoma is a relatively rare, benign peripheral nerve sheath tumor, whieh usually arises in either the dermis or subcutaneous tissue. These tumors may occur singly or as multiple lesions (plexiform neurilemmomatosis), We report an unusual case of plexiform neurilemmomatosis associated with cafe au lait spots reminiscent of neurofibromatosis clinically and another case of plexiform neurilemmoma on the finger. A Biopsy revealed the characteristic palisaded arrangement of spindle cells within well circumscribed elongated nodules, The skin lesions were completely excised without recurrence thereafter.
Biopsy ; Cafe-au-Lait Spots ; Dermis ; Fingers ; Neurilemmoma* ; Neurofibromatoses ; Peripheral Nerves ; Recurrence ; Skin ; Subcutaneous Tissue