Diffuse plane xanthoma characteristically presents with asymptomatic, yellow-orange plaques that usually involve periorbital areas, neck, upper trunk and flexural folds. Al-though most cases of diffuse plane xanthoma are associated with multiple myeloma, several cases have been described with different lymphoproliferative disorders and other miscellaneous diseases. We report herein two cases of diffuse plane xanthoma which are not associated with underlying disease.
Lymphoproliferative Disorders ; Multiple Myeloma ; Neck ; Xanthomatosis*

Childhood granulomatous perioral dermatitis is a distinctive granulomatous process of unknown cause with a benign and self-limited course and no associated systemic manifestations. We herein report a case of a 12-year-old Korean girl with multiple, discrete, monomorphic, flesh-colon, papular eruptions on the perioral, periocular, and perinasal areas of 7-month duration. Histopathologic examination revealed upper dermal and perifollicular granulomatous infiltrate.
Child ; Dermatitis, Perioral* ; Female ; Humans

Preoperative diagnosis of heterotopic pregnancy is difficult, especially when ectopic component is chronic and the precise effect of chronic tubal pregnancy on coexisting intra-uterine pregnancy or ongoing pregnancy rates is not known. We present the case of heterotopic pregnancy with a chronic tubal pregnancy incidentally diagnosed during term cesarean delivery in infertile woman conceived after ovulation induction using sequential clomiphene citrate and human menopausal gonadotropin, and timed coitus. Chronic tubal pregnancy might not affect the intrauterine gestation or the mother negatively in non-ruptured cases.
Clomiphene ; Coitus ; Female ; Gonadotropins ; Humans ; Mothers ; Ovulation ; Ovulation Induction ; Pregnancy ; Pregnancy Rate ; Pregnancy, Heterotopic ; Pregnancy, Tubal

Preoperative diagnosis of heterotopic pregnancy is difficult, especially when ectopic component is chronic and the precise effect of chronic tubal pregnancy on coexisting intra-uterine pregnancy or ongoing pregnancy rates is not known. We present the case of heterotopic pregnancy with a chronic tubal pregnancy incidentally diagnosed during term cesarean delivery in infertile woman conceived after ovulation induction using sequential clomiphene citrate and human menopausal gonadotropin, and timed coitus. Chronic tubal pregnancy might not affect the intrauterine gestation or the mother negatively in non-ruptured cases.
Clomiphene ; Coitus ; Female ; Gonadotropins ; Humans ; Mothers ; Ovulation ; Ovulation Induction ; Pregnancy ; Pregnancy Rate ; Pregnancy, Heterotopic ; Pregnancy, Tubal

Churg-Strauss syndrome (CSS) is a very rare disease which combines the features of asthma, hypereosinophilia, multisystem necrotizing vasculitis and extravascular granuolma. To our knolwedge, there have been four reports in Korean journals, but none in dermatology journals. We report a 37-year-old male who had allergic rhinitis, pansinusitis, a history of atopic dermatitis, multiple prurigo-nodularis like skin lesions, non-fixed interstitial lung in-filtration, hypereosinophilia and subclinical asthma. Clinical and histopathological features of his skin lesions were nonspecific where perivascular lymphocytic infiltration and mild lymphocytic vasculitis were shown. The presence of a pituitary mass and proximal myopathy as op-posed to peripheral neuropathy have not been reported in previous reports of CSS. However, other features of our patient met the criteria of CSS.
Adult ; Asthma ; Churg-Strauss Syndrome* ; Dermatitis, Atopic ; Dermatology ; Humans ; Lung ; Male ; Muscular Diseases ; Peripheral Nervous System Diseases ; Rare Diseases ; Rhinitis, Allergic ; Skin ; Vasculitis

Plexiform neurilemmoma is a relatively rare, benign peripheral nerve sheath tumor, whieh usually arises in either the dermis or subcutaneous tissue. These tumors may occur singly or as multiple lesions (plexiform neurilemmomatosis), We report an unusual case of plexiform neurilemmomatosis associated with cafe au lait spots reminiscent of neurofibromatosis clinically and another case of plexiform neurilemmoma on the finger. A Biopsy revealed the characteristic palisaded arrangement of spindle cells within well circumscribed elongated nodules, The skin lesions were completely excised without recurrence thereafter.
Biopsy ; Cafe-au-Lait Spots ; Dermis ; Fingers ; Neurilemmoma* ; Neurofibromatoses ; Peripheral Nerves ; Recurrence ; Skin ; Subcutaneous Tissue

BACKGROUND: The clinical efficacy of oral isotretinoin in the treatment of severe acne is well established but there is no published data about the recurrence rate and the optimum dose for lowest recurrence in Korean patients. OBJECTIVE: The objective of this study was to determine the recurrence rate after one course of isotretinoin in oriental cases. METHODS: Sixty eight cases were available which fulfilled the inclusion criteria ; clearing af- l ter one course more than 10 weeks and at least two year follow-up thereafter. Isotretinoin was used with oral dosage 0.3-1 mg/kg/day (0.6±0.1) with duration from 10 to 46 weeks (19.7±6.2). RESULTS: Overall, 78% of patients had relapsed with most requiring topical antibiotic therapy only. In patients receiving more than 120 mg/kg, the percentage without recurrence was 75 % which was significantly higher (p<0.001) in comparison with only 15 % among patients receiving less than 120 mg/kg. Doses between 100 and 120 mg/kg were not as effective as those ones with more than 120 mg/kg for preventing recurrence. CONCLUSION: The results indicate that moderate doses of isotretinoin are well tolerated and pro-duce excellent clearing. However, in order to minimize recurrence rate, the optimum dose may be at least over 120 mg/kg of the cumulative dose which means more than 6 months of treatment in most of the Korean patients with acne.
Acne Vulgaris* ; Follow-Up Studies ; Humans ; Isotretinoin* ; Recurrence*

Lichenoid keratosis (LK), a lichen planus-like keratosis, is a rather frequent skin disorder that has some histological features similar to lichen planus. However, the classification system for LK has not been settled. We report two cases of LK and propose a new classification for LK correlating with clinicohistopathological findings.
Actins* ; Classification ; Keratosis* ; Lichen Planus ; Lichens ; Skin

No abstract available.
Steatocystoma Multiplex*

No abstract available.
Histiocytic Necrotizing Lymphadenitis* ; Lymphohistiocytosis, Hemophagocytic*