No abstract available.
Wound Healing* ; Wounds and Injuries*

The age of puberty represents a very critical time in the life history of every young woman. The menarche stands as primary indicator of the onset of sexual maturation in females. According to several studies, menarcheal age in Korean girls has dropped from about 15 years of age in 1960s to 13.5 years of age in 1980s. This findings show a pronounced secular trend to earlier maturation. The purpose of this study is to determine (1) the average age at menarche in Korea in present time, (2) the secular trend of menarcheal age, and (3) the geographic regional influence on menarche. The data sampling was obtained from the physical examination cards of women students in Yonsei University who entered from 1983 to 1991. The data which was obtained from the number of 7761 was analysed by dBase III plus and SAS program. The results are as follows: 1) The mean menarcheal age of the subjects was 13.7+/-1.2 years. 2) Age at menarche has been getting earlier by some 7.4 months during the period of recent II years. 3) Comparing to the decreasing secular trend of menarcheal age, the height and weight showed increasing trend. 4) There were significant differences in menarcheal age, height, weight among geographic regions. We conclude that the results indicate an accelerating secular trend in age of menarche in Korea.
Adolescent ; Female ; Humans ; Korea* ; Menarche ; Physical Examination ; Puberty ; Sexual Maturation

This study was undertaken to investigate the skin sensitivity to 54 different allergens in 248 patients of 81 acute urticaria, 141 chronic urticaria and 26 atopic dermatitis, who visited in Department of Dermatology, College of Medicine, Chung Ang University Hospital from February 1986 to January 1987. The results were as follows . 1. The sex ratio of male to female of 248 patients with allergic state was 1.1: 1 (130: 118) and third and fourth decades occupied 56.5%. In regard to the duration of chronic urticaria, less than 1 year were 31.2% and between 1 to 3 years were 28.3%. 2. In acute urticaria, the prick test positive reactivity to allergens were in descending order to mite, household insect mixture, Trichophyton mixture, house dust, mold mixture C and silk, whereas in chronic urticaria ', mite, household insect mixture, house dust, cockroaeh mixture, Trichophyton mixture and silk and in atopic dermatitis ; mite, house dust, Trichophyton mixture, household insect mixture, mold mixture A and C. 3. The positive reactivities of allergens in patients with atopic dermatitis, chronic urticaria and acute urticaria were 69.2%, 52.5% and 35.8%, respectively. 4. The positive reactivity to compound allergens were higher than to single and the most frequent combinations were 2 to 5 allergens (85.4%). 5. Out of 54 allergens used in this study, 49 allergens were reactive and the most frequent group of allergens were house dusts (41.5%) and commonly involved allergens were mite (27.8%), household insect mixture (15.7%), house dust (13.7%), Trichophyton mixture (11.7%) and cockroach mixture(7.7%). 6. Common other allergic diseases combined with atopic dermatitis were rhinitis and bronchial asthma, occuring in 23.1%.
Allergens ; Asthma ; Cockroaches ; Dermatitis, Atopic* ; Dermatology ; Dust ; Family Characteristics ; Female ; Fungi ; Humans ; Insects ; Male ; Mites ; Pyroglyphidae ; Rhinitis ; Sex Ratio ; Silk ; Skin ; Trichophyton ; Urticaria

We experienced a 57-year-old male patient who have had multiple coin sized, erythematous, psinful, indurated ulcerations with purulent discharge on the right calf area since 10 years before. Previously he received injections of paraffin in the lesion site for correcting the thinning of right calf due to complication of pyoderma. Histopathologic examination showed "Swiss cheese" appearance of parsffinoma. Good result was obtained after treatment with surgical excision and split thickness skin graft.
Humans ; Male ; Middle Aged ; Numismatics ; Paraffin ; Pyoderma ; Skin ; Transplants ; Ulcer

No abstract available.
Pyelonephritis, Xanthogranulomatous* ; Wilms Tumor*

Patients with atypical or incomplete Kawasaki disease are at same risk for development of coronary artery complications as typical Kawasaki disease. In this communication we report six patients with unusual presentation of Kawasaki disease complicated by coronary artery aneurysms, in whom correct diagnosis were not made in time for proper treatment. One of these patients died from massive myocardial ischemia due to giant aneurysms along the entire coronary artery system. These patients had either less than enough number of diagnostic criteria at initial presentation or diagnostic signs which occurred over an extended period of time, resulting in difficulty in diagnosis during the acute phase. As a result, none of these patients received intravenous gamma globulin treatment. Thus strict adherence to currently accepted criteria for diagnosis of Kawasaki disease may lead to failure to recognize atypical form of this illness with potential sequelae of myocardial ischemia or sudden death. We would like to emphasize from this experience that clinicians must be aware of the wide variations in clinical presentation of Kawasaki disease and take an aggressive approach in making correct diagnosis by obtaining early cardiac evaluation in order to initiate prompt treatment with intravenous gamma globulin.
Aneurysm ; Coronary Aneurysm* ; Coronary Vessels ; Death, Sudden ; Diagnosis ; gamma-Globulins ; Humans ; Mucocutaneous Lymph Node Syndrome* ; Myocardial Ischemia

Rett syndrome is progressive neurodegenerative disorder in female patients, characterized by autistic behavior, mental retardation, loss of purposeful hand skills, stereotypic hand movement, breathing dysfunction, severely impaired language, ataxia, and seizure. The diagnosis of Rett syndrome is based on its characteristic clinical manifestation and course. The electroencephalographic (EEG) findings of Rett syndrome are nonspecific, but a progressive deterioration in the EEG, characterized by a slowing of background activity and spike sharp wave discharges, may be observed. We experienced one case of Rett syndrome in a 5 year old girl having mental retardation, loss of purposeful hand skills, stereotypic hand movements (clapping, washing, hand-to-mouth), breathing dysfunction (hyperventilation/apnea). Her EEG findings on Video-EEG monitoring are excessive slowing waves during awake state and frequent spike discharges from left or centrotemporal area during sleeping. We report a case of Rett syndrome with brief review of related literatures.
Ataxia ; Child, Preschool ; Diagnosis ; Electroencephalography ; Female ; Hand ; Humans ; Intellectual Disability ; Neurodegenerative Diseases ; Respiration ; Rett Syndrome* ; Seizures

No abstract available.
Infectious bursal disease virus*

No abstract available.
Autonomic Pathways* ; Rectal Neoplasms* ; Urodynamics*

In older people, medicines are considered appropriate when they have an evidence-based indication, are well-tolerated and cost-effective. However, inappropriate prescribing (IP) is a common and significant healthcare problem in elderly people in Korea as well as in the world. IP in old people is highly prevalent but preventable. Screening for IP is highly desirable, since detection and correction are simple and worthwhile. Until now, Beers' criteria for IP dominate the international literatures, although they have some defects. The 2002 version of Beers' criteriaindependent of diagnosis includes 48 different categories of either single medications or multiple medications of a similar class identified as IP, and the 2002 version of Beers' criteria-considering diagnosis contains 19 different categories containing possible drug-disease interaction. Successful approaches to optimizing prescribing have been either educational or administrative. More research specially focused on the IP in the elderly is needed.
Aged ; Delivery of Health Care ; Humans ; Inappropriate Prescribing ; Korea ; Mass Screening