1.Transvaginal Sonographic Evaluation of Uterine Wall Thickness on Prior Cesarean Scar.
Joo Yun CHO ; You Me LEE ; In Hyun KIM ; Chang Jo CHUNG ; SSung Woon CHANG
Korean Journal of Obstetrics and Gynecology 1999;42(10):2229-2234
OBJECTIVES: Estimation of the anterior lower uterine segment (LUS) thickness difference who underwent prior cesarean delivery measured with transvaginal sonography at or after 36 gestational weeks (sonographic thickness) and a ruler during elective cesarean section (operation thickness) Methods: One hundred sixty women who underwent prior cesarean delivery had the thickness of their LUS measured with transvaginal sonography at or after 36 gestational weeks. The LUS thickness was measured with a ruler during elective cesarean section. We compared group I whose LUS was fairly well visualized 4 cm or more from the uterine cervix to group II which had less than 4 cm. RESULTS: The mean sonographic thickness of LUS was 1.7 0.8 mm and that of operation thickness was 1.9 0.5 mm. The mean difference of the two (thickness difference) was 0.5 0.5 mm. In 31.3% the sonographic thickness was same as the operation thickness and in 70.7% of the total with 0.5 mm or less difference, the sonographic thickness could be regarded as accurate. The thickness difference with the sonographic thickness with 2 mm or more was smaller than those with 1 mm or less (0.4 0.5; 0.6 0.6) and that of group I was smaller than that of group II (0.4 0.4; 0.9 0.6) (p< .05). CONCLUSION: The thickness difference was 0.5 0.5 mm and it was smaller when the LUS thickness is 2 mm or over, clearly visible 4 cm or over from the cervix.
Cervix Uteri
;
Cesarean Section
;
Cicatrix*
;
Female
;
Humans
;
Pregnancy
;
Ultrasonography*
2.A Case of Collecting Duct Carcinoma of Kidney.
Joong Won WOO ; So Jin YOU ; Chang Kyu LEE ; Hyun Yul RHEW
Korean Journal of Urology 1997;38(5):551-554
Most renal carcinomas are thought to originate from the epithelial cells of proximal convoluted tubules in the renal cortex. Collecting duct carcinoma is a recently recognized histological variety of renal cell carcinoma considered to arise from the epithelium of the collecting ducts. It is important to distinguish the collecting duct carcinoma from ordinary renal cell carcinoma, because which has an aggressive clinical course with early metastasis and death. But in patients, the natural course of the disease and its response to treatment have not been clearly established. Herein we report a case of collecting duct carcinoma of kidney in 38-year-old woman who had generalized edema and left flank dull pain. The preoperative diagnosis was left renal cell carcinoma on physical examination and radiologic finding, and left radical nephrectomy was done.
Adult
;
Carcinoma, Renal Cell*
;
Diagnosis
;
Edema
;
Epithelial Cells
;
Epithelium
;
Female
;
Humans
;
Kidney*
;
Neoplasm Metastasis
;
Nephrectomy
;
Physical Examination
3.The Relationship between Musculoskeletal Symptoms and Type A Behavior Patterns in Housewife.
Hee Ja CHOI ; Hyun Rim CHOI ; Chang Rae LEE ; Chun Deok YOU
Journal of the Korean Academy of Family Medicine 1997;18(2):212-220
BACKGROUND: The psychosocial factors to the musculoskeletal disease has been studied recently as well as environmental factors. Type A behavior pattern which is an independent risk factor for coronary heart disease may have relation to musculoskeletal disease, and the authors studied the relations for these variables. METHODS: The studied subjects were 511 housewives sampled without intention at Taejon city and we excluded 76 persons who had experiences of trauma at neck, shoulder or back region during recent one year on the data analysis. The musculoskeletal symptoms and type A behavior pattern were quantified as the score and the Spearmans correlation coefficient was used to reveal the statistical significance for the relations. RESULTS: Type A behavior pattern had the relation to the symptoms of neck, sboulder, and back region. For the sociodemographic variables, the relations were significant for the group of younger age, lower socioeconomic level, and the group having full time job, lower body mass index. CONCLUSIONS: We concluded that type A behavior pattern was the possible risk factor for musculoskeletal disease, but more studies will be necessary to confirm the influence of behavior pattern to musculoskeletal disease.
Body Mass Index
;
Coronary Disease
;
Daejeon
;
Humans
;
Intention
;
Musculoskeletal Diseases
;
Neck
;
Psychology
;
Risk Factors
;
Shoulder
;
Statistics as Topic
4.Home Health Resource Utilization Measures Using a Case-Mix Adjustor Model.
Journal of Korean Academy of Nursing 2005;35(5):774-786
PURPOSE: The purpose of this study was to measure home health resource utilization using a Case-Mix Adjustor Model developed in the U.S. METHOD: The subjects of this study were 484 patients who had received home health care more than 4 visits during a 60-day episode at 31 home health care institutions. Data on the 484 patients had to be merged onto a 60-day payment segment. Based on the results, the researcher classified home health resource groups (HHRG). RESULT: The subjects were classified into 34 HHRGs in Korea. Home health resource utilization according to clinical severity was in order of Minimum (C0) < 'Low (C1) < 'Moderate (C2) < 'High (C3), according to dependency in daily activities was in order of Minimum (F0) < 'High (F3) < 'Medium (F2) < 'Low (F1) < 'Maximum (F4). Resource utilization by HHRGs was the highest 564,735 won in group C0F0S2 (clinical severity minimum, dependency in daily activity minimum, service utilization moderate), and the lowest 97,000 won in group C2F3S1, so the former was 5.82 times higher than the latter. CONCLUSION: Resource utilization in home health care has become an issue of concern due to rising costs for home health care. The results suggest the need for more analytical attention on the utilization and expenditures for home care using a Case-Mix Adjustor Model.
Risk Adjustment
;
Middle Aged
;
Male
;
Korea
;
Humans
;
Home Care Services/*utilization
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Health Resources/*utilization
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Female
;
Aged, 80 and over
;
Aged
;
Adult
5.A Case of Subcutaneous Juvenile Xanthogranuloma.
Jeong Deuk LEE ; Chung Eui YOU ; Chang Nam LEE ; Hoon KANG ; Sang Hyun CHO
Annals of Dermatology 2003;15(1):31-33
Juvenile xanthogranuloma is a congenital or perinatal tumor, 1 to 2 cm in diameter, usually located on the head. The extracutaneous lesions can occur on the eye, the lung, the epicardium, the oral cavity or the testicles. Subcutaneous form of juvenile xanthogranuloma has been reported very rarely in the literature. We report a unique case of a subcutaneous juvenile xanthogranuloma that showed 4 × 4 cm sized plaque and located on the extremity of 9-year-old girl.
Child
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Extremities
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Female
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Head
;
Humans
;
Lung
;
Mouth
;
Pericardium
;
Testis
;
Xanthogranuloma, Juvenile*
7.The Relationship between ST-T Electrical Alternans on EKG and Ventricular Arrhythmia.
You Hong KIM ; Seong Yun O ; Dal Soo LIM ; Dae Seong HYUN ; Sung Gug CHANG ; Young Hoon YOU ; Young Jo KIM ; Bong Sup SHIM ; Hyun Woo LEE
Korean Circulation Journal 1990;20(3):305-314
In order to observe the development of ventricular arrhythmia during regional myocardial ischemia and reperfusion, especially under the presence or absence of ST-T electrical alternans on epicardial EKG. The proximal left descending coronary artery(LAD) was ligated for 20 minutes and then reperfused suddenly in twenty-three cats. Standard lead EKG(Lead??, chest lead EKG and epicardial lead EKG were recorded simultaneously during the occlusion and reperfusion respectively. During the ligation of LAD, STEA was observed in thirteen cats(56.5%). In occlusion period, the incidence of ventricular tachycardia in STEA positive group was significantly higher than in the negative group(p<0.01) and arrhythmic score was significantly higher(p<0.005) also In the reperfusion period the incidence of vefntricular fibrillation in STEA positive group was significantly higher than in the negative group(p<0.025). But there was the tendency to be higher in arrhythmic score of STEA positive group. There were no differences in heart rate, systolic left ventricular pressure, ST elevation and ST width in both groups. Most forms of ST-T of sinus rhythm before and after development of ventricular premature beat was low form(L). It was concluded that at the presence of STEA on EKG, the incidence of ventricular arrhythmia was more prevalent. So, STEA can be available as a marker of ventricular arrhythmia and prognostic factor.
Animals
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Arrhythmias, Cardiac*
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Cardiac Complexes, Premature
;
Cats
;
Electrocardiography*
;
Heart Rate
;
Incidence
;
Ligation
;
Myocardial Ischemia
;
Reperfusion
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Tachycardia, Ventricular
;
Thorax
;
Ventricular Pressure
8.Progressive Outer Retinal Necrosis Combined with Vitreous Hemorrhage in a Patient with Acquired Immunodeficiency Syndrome.
Yong Sung YOU ; Sung Jin LEE ; Sung Ho LEE ; Chang Hyun PARK ; Oh Woong KWON
Korean Journal of Ophthalmology 2007;21(1):51-54
PURPOSE: To describe an unusual case of rapidly progressive outer retinal necrosis (PORN) with vitreous hemorrhage in a 41-year-old woman with acquired immunodeficiency syndrome (AIDS), who had retinitis developed from what was probably varicellar-zoster virus combined with cytomegalovirus (CMV) and herpes simplex type 1,2, as proven by the polymerase chain reaction restriction fragment length polymorphism method (PCR-RFLP). METHODS: This study is a case report detailing clinical follow-up and an aqueous humor test by PCR-RFLP. RESULTS: The deep, white retinal lesions coalesced and progressively expanded in a circumferential manner, with sparing of the perivascular retina. However, retinal and vitreous hemorrhages, unusual findings for PORN, could be noted around the optic nerve. Varicellar-zoster virus (VZV), cytomegalovirus (CMV), and herpes simplex types 1,2 (HSV-1,2) were detected in the aqueous humor by PCR. CONCLUSIONS: PORN has been described as a variant of necrotizing herpetic retinopathy, occurring particularly in patients with AIDS. Although the etiologic agent has been reported to be VZV, concurrent or combined etiologic agents can include HSV-1, HSV-2, and CMV in AIDS patients. Therefore, combined antiviral therapy with acyclovir and ganciclovir could be more reasonable as an initial therapy.
Vitreous Hemorrhage/*complications
;
Retinitis/*complications/pathology/*virology
;
Necrosis
;
Humans
;
*Herpes Zoster
;
Female
;
Disease Progression
;
Adult
;
Acquired Immunodeficiency Syndrome/*complications
9.The Effect of Intravitreal Bevacizumab Injection before Trabeculectomy in Patients with Neovascular Glaucoma.
You Hyun LEE ; Rebecca KIM ; Sung Dong CHANG
Journal of the Korean Ophthalmological Society 2015;56(6):917-924
PURPOSE: To evaluate the efficacy of preoperative intravitreal bevacizumab injection (IVBI) and prognostic factors of surgical success in neovascular glaucoma patients, who underwent trabeculectomy. METHODS: A total of 58 patients (58 eyes) diagnosed with neovascular glaucoma who underwent trabeculectomy between 2003 and 2013 were enrolled in this retrospective study. Trabeculectomy with mitomycin C was performed between 2003 and 2006 and additional preoperative IVBI with the above mentioned technique was performed between 2007 and 2013. To evaluate the efficacy of preoperative IVBI, the patients were divided into the preoperative IVBI group and control group. Best corrected visual acuity (BCVA) and intraocular pressure (IOP) were measured from preoperative to postoperative 12 months. To evaluate the prognostic factors related to surgical success, the following was investigated: age, lens status, preoperative IVBI, time interval between preoperative IVBI and trabeculectomy, previous vitrectomy and, postoperative complications. RESULTS: Trabeculectomy with mitomycin C only was performed in 26 eyes and additional preoperative IVBI was performed in 32 eyes. Surgical success was 81.3% in the IVBI group and 57.7% in the control group at postoperative 6 months (p = 0.012), and 78.1% in the IVBI group and 50.0% in the control group at postoperative 12 months (p = 0.021). Statistically significant IOP reduction effect was observed in the IVBI group (p = 0.048), and reduced anti-glaucoma eye drop usage was observed in the IVBI group (0.4) compared with 0.8 in the control group (p = 0.040). Postoperative hyphema (hazard ratio [HR] = 2.872, p = 0.044) and preoperative IVBI (HR = 0.280, p = 0.030) were considered risk factors for surgical failure in univariate analysis, however, only preoperative IVBI was statistically significant in multivariate analysis (p = 0.046). CONCLUSIONS: In neovascular glaucoma patients, preoperative IVBI before trabeculectomy is a good prognostic factor of surgical success and shows benefit in lowering the IOP and reducing anti-glaucoma eye drop usage at postoperative 1 year.
Glaucoma, Neovascular*
;
Humans
;
Hyphema
;
Intraocular Pressure
;
Mitomycin
;
Multivariate Analysis
;
Postoperative Complications
;
Retrospective Studies
;
Risk Factors
;
Trabeculectomy*
;
Visual Acuity
;
Vitrectomy
;
Bevacizumab
10.The upstream sequence of Mycobacterium leprae 18-kDa gene confers transcription repression activity in orientation-independent manner.
Experimental & Molecular Medicine 2004;36(6):510-514
In order to understand the role of the upstream region of the Mycobacterium leprae 18-kDa gene on the gene regulation, the region was divided into two at the -50 position from the first start codon of the gene and their effect on transcription was examined by using a LacZ transcriptional reporter gene assay. The presence of each of these two regions conferred transcription repression not only on its cognate M. lepraerae 18-kDa gene promoter, but also on a heterologous promoter such as the Mycobacterium bovis BCG hsp65 gene promoter. Moreover, it was found that these regions could confer transcription repression activity in both cases in an orientation-independent manner. Thus, these results indicate that the upstream region of the M. leprae 18-kDa gene harbors transcription repression responsive element(s) acting as an operator and can be further divided into two separately functional regions, suggesting a bipartite structure of the element(s). The identification of transcription repression activity of the upstream region in the M. leprae 18-kDa gene will contribute greatly for the understanding of the 18-kDa gene regulation mechanism, and provide also useful information for the manipulation of mycobacterium gene expression.
Bacterial Proteins/*genetics
;
Down-Regulation/*genetics
;
*Gene Expression Regulation, Bacterial
;
Mycobacterium leprae/*genetics
;
Response Elements/*genetics
;
Transcription, Genetic