No abstract available.
Status Epilepticus*

No abstract available.
Child* ; Humans ; Korea*

No abstract available.
Cells, Cultured* ; Mycoplasma*

Cytokines are hormone-like proteins which mediate and regulate inflammatory and immune responses. The purpose of this study was to investigate the effect of lipopolysaccharide (LPS), Staphylococcus enterotoxin B (SEB), and Mycoplasma lysates on regulation of IL-6 and IL-8 production by human nasal fibroblasts. Primary cultured cells were incubated with LPS (1.0 ug/ml) from E.coli, SEB (1.0 ug/ml) from S.aureus, or Mycoplasma lysates (M.pneumoniae, Mp; M. fermentans, Mf; M. hominis, Mh, each 1.0 ug/ml). The culture supernatants were collected at 2, 6, and 24 hr and assessed for IL-6 and IL-8 production by enzyme-linked immunosorbent assay. The production of IL-6 in the culture supematant was downregulated by LPS, SEB, or Mycoplasma lysates. But IL-6 was upregulated by mixed exposure with Mp+LPS (2 hr), Mp+LPS+SEB (24 hr), Mf+LPS (24 hr), Mf+LPS+SEB (2 hr), Mh+LPS (24 hr), Mh+SEB (24 hr), or Mh+LPS+ SEB (24 hr). The production of IL-8 in the culture supematant was similar to that of IL-6 by same stimulants. But IL-8 was upregulated by mixed exposure with Mf+LPS+SEB (2 hr), Mh+LPS (24 hr), Mh+ SEB (24 hr), or Mh+LPS+SEB (24 hr). These studies show that costimulation of LPS or SEB with Mycoplasma whole cell lysates upregulates the production of IL-6 and IL-8.
Bacterial Toxins* ; Cells, Cultured ; Cytokines ; Enterotoxins ; Enzyme-Linked Immunosorbent Assay ; Fibroblasts* ; Humans* ; Interleukin-6 ; Interleukin-8 ; Mycoplasma* ; Staphylococcus

Reverse total shoulder arthroplasty has been performed with promising results in rotator cuff tear arthropathy. However, the global complication of the reverse total shoulder arthroplasty is relatively higher than that of the conventional total shoulder arthroplasty. Neurologic complications after reverse total shoulder arthroplasty are rare but there are sometimes remaining sequelae. The cause of the neurologic complication is multifactorial, including arm traction, position and the design of the implant. Most cases of neurologic palsy following reverse total shoulder arthroplasty occur in the axillary nerve and the radial nerve. The authors report on a case of a 71-year-old man with isolated musculocutaneous nerve palsy after reveres total shoulder arthroplasty with related literature.
Aged ; Arm ; Arthroplasty* ; Humans ; Musculocutaneous Nerve* ; Paralysis* ; Radial Nerve ; Rotator Cuff ; Shoulder* ; Tears ; Traction

Heterotopic ossification(HO) is a frequent complication of total hip arthroplasty(THA), If it is sevre enough, it can convert a successful result of the operation into a poor one. Among several strategies that researches in recent years have tested, radiation therapy have been accepted to have efficacy for prevention of heterotopic ossification by many authors. While postoperative irradiation has been shown to lower the incidence of HO effectively in high risk patients following THA, patients in multiple dose protocols continue to develop some heterotopic ossifiction despite therapy and have some problems. Ninteen patients received single dose exposure to 600 rad delivered within 48 hours of THA with shielding of prosthesis region. The patients were considered high risk group for developing HO because of hypertropic osteoarthritis, post-traumatic osteoarthritis or the presence of previous formed ectopic bone. The average follow up period was 10.2 months(range 6 months
Arthroplasty, Replacement, Hip ; Follow-Up Studies ; Hip ; Humans ; Incidence ; Ossification, Heterotopic ; Osteoarthritis ; Osteogenesis ; Prostheses and Implants

BACKGROUND: To investigate the effectiveness of reverse total shoulder arthroplasty (RTSA) in treating irreparable massive rotator cuff tears (RCTs). METHODS: Twenty-nine patients who underwent RTSA for the treatment of irreparable massive RCTs and completed follow-up for at least 1 year were selected. Their mean age was 69.7 years (range, 59-80 years). The mean follow-up was 17.7 months (range, 12-42 months). The shoulder range of motion was measured preoperatively and at final follow-up. The functional result was evaluated using visual analog scale (VAS) for pain, American Shoulder and Elbow Surgeon (ASES) score, and Korean Shoulder Society (KSS) score. Additionally, the shoulders were categorized into two groups depending on prior history of surgery and the clinical outcomes were analyzed between two groups. RESULTS: Mean pain VAS improved, from 6.6+/-1.2 to 2.7+/-0.9 (p=0.001), and the mean functional VAS from 35.7+/-4.2 to 73.3+/-5.4 (p=0.006). The mean ASES score improved from 37.2+/-2.8 to 75.0+/-3.8 (p=0.012). The mean KSS improved from 36.5+/-7.2 to 75.6+/-5.4 (p=0.009), the mean forward elevation from 66.3+/-4.7 to 135.6+/-8.4 (p=0.0001), and the mean abduction from 45.2+/-4.2 to 119.0+/-6.5o (p=0.0001). Internal rotation differed significantly from the first sacral to the third lumbar vertebrae (p=0.036). External rotation did not change significantly (p=0.076). There was also no statistically significant difference between groups (no previous operation versus none). Four complications occurred: one superficial infection, one with anterior dislocation, one acromial fracture, and one clavicle fracture. CONCLUSIONS: RTSA provides reliable pain relief and recovery of shoulder function in patients with massive irreparable RCTs in short-term follow-up.
Arthroplasty* ; Clavicle ; Dislocations ; Elbow ; Follow-Up Studies ; Humans ; Lumbar Vertebrae ; Range of Motion, Articular ; Rotator Cuff* ; Shoulder* ; Visual Analog Scale

No abstract available.
Arachnoid Cysts* ; Arachnoid* ; Humans

Clinical investigation of 20 cases of brain abscess has been done at the dept of Pediatric Yonsei Medical Center, who had been treated during the period of 8 years from January 1977 through Jun 1985. Following results has been obtained: 1. Of 20 patients, 14 patient was male and the rest 6 was female rating M:F ratio 2.3:1 and the youngest patient was undler 1 year, the oldest one was 15 years old. 2. The chief complaints at admission were headache, fever, vomiting in order of frequency, while neurologic signs were neck stiffiness, hemiparesis, papilledema etc. 3. The preceeding causative diseases of brain abscess were diseases involving ENT 15%, congenital heart disease 20%, head trauma 35% and the rest 20% the etiology of brain abscess was not determined. The abscess tended to occure at temporoparietal area in the cases associated with otitis media while abscess originating from congenital heart diseases tended to occure multiple area. 4. 10 cases out of 20 had lumbar puncture under the suspision of meningitis, 2 cases manifested normal CSF finding. Patients who has focal neurologic finding associated with OMPC or congenital heart disease should suspect for brain abscess, which can be easily conform by brain C-T scan as well as patient who manifested unusual clinical course. 5. Factor relating prognosis were mental state and duriation between onset of clinical symptom and time starting treatment; clear mental state and short duration reflect better prognosis. 6. The motality rate was 33%, and the neurologic sequelas were hemiparesis (36.4%), mental deficit (18.2), dysarthria, epilepsy, hydrocephalus and blindness.
Abscess ; Adolescent ; Blindness ; Brain Abscess* ; Brain* ; Child* ; Craniocerebral Trauma ; Dysarthria ; Epilepsy ; Female ; Fever ; Headache ; Heart Defects, Congenital ; Heart Diseases ; Humans ; Hydrocephalus ; Male ; Meningitis ; Neck ; Neurologic Manifestations ; Otitis Media ; Papilledema ; Paresis ; Prognosis ; Spinal Puncture ; Vomiting

No abstract available.
Hospitals, General* ; Humans ; Inpatients* ; Sleep Initiation and Maintenance Disorders*