1.The Morphometric Study on the Vermiform Appendix in Korean Adults.
Kyeong Han PARK ; Uhm Mee RYUNG ; Young Il HWANG ; Douk Ho HWANG ; Ka Young CHANG
Korean Journal of Physical Anthropology 1996;9(1):27-34
The anatomical structure of vermiform appendix was studied for 124 Korean adult cadavers and the articles were reviewed with special reference to its position and length. The results are as follows ; 1. On the frequency of positional types based on Wakeley (1933), postileal type was recorded most frequently (37.7%) and retrocecal type was found in 19.7% of cases, showing the difference from other ethnic groups whose most frequent position was retrocecal or pelvic type. 2. In the direction of appendix in relation to the clock, the direction between 1 and 3 o'clock was most frequently found. 3. Appendix of fixed form was found in 22.1% of cases, that of free form 77.9%. In free form, postileal type was found most frequently, but retrocecal type was met most frequently in fixed form. 4. The length of appendix was 5.95±1.64 cm (male ; 6.14±1.67 cm ; female 5.59±1.51 cm). Neither significant difference between sex nor positional type was noted. 5. Positions of appendix are seemed to be set up during fetal stage. The Ethnic variation in the positions of appendix is thought to be determined by inherited physical anthropological factor, not by postnatal one.
Adult*
;
Appendix*
;
Cadaver
;
Ethnic Groups
;
Female
;
Humans
2.The comparison of tocolytic effects between MgSO4 and ritodrine HCI in preterm labor.
Keun Young LEE ; Seung Yong LEE ; Sun Tae HWANG ; Chang Hwang HAN ; Seong Weon KANG
Korean Journal of Obstetrics and Gynecology 1993;36(12):3857-3864
No abstract available.
Female
;
Obstetric Labor, Premature*
;
Pregnancy
;
Ritodrine*
;
Tocolytic Agents*
3.Paragonimiasis on lumbar epidural space: A case report
In KIM ; Han CHANG ; Sung Chul KIM ; Sung Kwan HWANG ; Chang Suck KANG
The Journal of the Korean Orthopaedic Association 1994;29(2):511-514
Paragonimus westermani mainly infests the lung parenchyma, and it is also causes ectopic parasitism of various sites, such as brain, liver and subcutaneous tissue but there have been no reports in literature about paragonimiasis infesting lumbar epidural space. A 58-year-old housewife complained of lumbago and radiating pain to both lower extremities for 20 years. Calcified extradural masses were found by preoperative plain X-ray, myelogram, and CT scan. Intraoperatively, cystic mass in the epidural space at L2-3 was found and confirmed to be paragonimiasis by histopathological study. A case of ectopic paragonimiasis in the lumbar epidural space at L2-3 level is presented.
Brain
;
Epidural Space
;
Humans
;
Liver
;
Low Back Pain
;
Lower Extremity
;
Lung
;
Middle Aged
;
Paragonimiasis
;
Paragonimus westermani
;
Subcutaneous Tissue
;
Tomography, X-Ray Computed
4.MRI of Intraspinal Cysticercosis.
Seung Cheol KIM ; Moon Hee HAN ; Kee Hyun CHANG ; Gi Seok HAN ; Hee Young HWANG
Journal of the Korean Radiological Society 1995;32(1):33-37
PURPOSE: To describe the MR features of intraspinal cysticercosis. MATERIALS AND METHODS: Medical records and MR images of four cases of intraspinal cysticercosis were retrospectively reviewed. The MR findings were described with regard to the location and signal intensity of the lesions, contrast enhancement, presence or absence of associated intracranial cysticerci, and other findings. RESULTS: There were three cases of subarachnoidal form and one case of intramedullary form. Cysticerci of subarachnoidal form in three cases were located in retromedullary space at C2 level, anterior to cord at C1 -C6 levels, and lumbosacral area, respectively. The signal intensities of the lesions were same as those of CSF. Localized arachnoidal enhancement was found in all three cases. In one case there was a large area of high signal intensity within the spinal cord on T2 weighted image suggesting either ischemia secondary to vascular compromise or inflammatory edema. All of these three cases accompanied intracranial cysticercosis. Intramedullary cysticercosis in one case was shown as a single I cm cystic lesion at C2 level, which showed hypointense signal on T1 weighted image, hyperintense signal on T2-weighted image, and signet-ring-like enhancement. This lesion did not accompany intracranial cysticerci. CONCLUSION: lntraspinal cysticercosis manifested as single or multiple cysts within either spinal cord or subarachnoid space, and were frequently associated with arachnoiditis.
Arachnoid
;
Arachnoiditis
;
Cysticercosis*
;
Edema
;
Ischemia
;
Magnetic Resonance Imaging*
;
Medical Records
;
Retrospective Studies
;
Spinal Cord
;
Subarachnoid Space
5.A Case of Wiskott-Aldrich Syndrome.
Byoung Geun LEE ; Soo Hee CHANG ; Soo Young CHO ; Pyoung Han HWANG ; Jung Soo KIM
Journal of the Korean Pediatric Society 1994;37(11):1615-1619
Wiskott-Aldrich Syndrome is an X-linked disorder characterized by recurrent infection, thrombocypenia and eczema. Various defects in cell-mediated immunity and deficient antibody reponse to carbohydrate antigens have been described. We experienced a case of Wiskott-Aldrich Syndrome of 28 months old male patient. He has been suffered from multiple petechiae with bleeding, recurrent pyogenic infections and generalized eczema since 3 months of age. Immunological abnormalities are as follows: 1) Serum IgM was gradually decreased, while IgA and IgE were increased. 2) Antibody response against polysaccharide antigen (PRP) was not observed after 3 times of PRPT immunization. 3) CD4/CD8 ratio was reversed (0.6). 4) Proliferative response of mononuclear cells was significantly reduced, and CMI skin test also showed negative results. A brief review of literature was made.
Antibody Formation
;
Child, Preschool
;
Eczema
;
Hemorrhage
;
Humans
;
Immunity, Cellular
;
Immunization
;
Immunoglobulin A
;
Immunoglobulin E
;
Immunoglobulin M
;
Male
;
Purpura
;
Skin Tests
;
Wiskott-Aldrich Syndrome*
6.The clinical studies on acute poisoning of infants and children visited the emergency room in rural area.
Chang Hi LEE ; Gyu Dong CHOI ; Hyeon Soo HAN ; Hye Heon HWANG ; Myung Ho CHO
Journal of the Korean Academy of Family Medicine 1991;12(2):40-46
No abstract available.
Child*
;
Emergencies*
;
Emergency Service, Hospital*
;
Humans
;
Infant*
;
Poisoning*
7.Intracranial carvenous hemangiomas: comparison of MRI and CT.
Hee Young HWANG ; Hyun Ki YOON ; In One KIM ; Moon Hee HAN ; Kee Hyun CHANG
Journal of the Korean Radiological Society 1991;27(4):465-472
No abstract available.
Hemangioma*
;
Magnetic Resonance Imaging*
8.Placental Transfer of Anti-H. influenzae Type b Specific IgG and Subclasses.
Soo Hee CHANG ; Moon Hwan LEE ; Pyoung Han HWANG ; Soo Chul CHO ; Jung Soo KIM
Journal of the Korean Pediatric Society 1995;38(12):1638-1644
No abstract available.
Immunoglobulin G*
;
Influenza, Human*
9.A case of human rail.
Chang Hwang HAN ; Duk Kyun LEE ; Tae Wook SONG ; Keun Young LEE ; Sung Won KANG
Korean Journal of Obstetrics and Gynecology 1992;35(1):130-135
No abstract available.
Humans*
10.Survival, Differentiation and ATM Phenotype of PC-12 Cells by Down - regulation of AT Gene.
Ho Keun YI ; Soo Hee CHANG ; Dae Yeol LEE ; Jung Soo KIM ; Pyoung Han HWANG
Journal of the Korean Cancer Association 1999;31(5):1065-1073
PURPOSE: Ataxia Telangiectasia (AT) is a hereditary multi-systemic disease resulting from mutations of AT gene and is characterized by progressive neurodegeneration, cancer, immune system defects, and hypersensitivity to ionizing radiation. AT gene has a homologue sequence of PI3-kinase. The activity and cellular function of PI3-kinase in AT gene remains unclear. This study was undertaken to evaluate the function of AT gene through the effect on cell survival and differentiation by the inhibition of AT gene expression. MATERIALS AND METHODS: NH2-terminal portion of AT gene was isolated from MCF-7 cells by RT-PCR. The isolated DNA fragment was ligated in reverse orientation in pcDNA3. This antisense ATM expression vector was transfected to PC-12 cells by calcium phosphate method, and the transformed cells were selected using G418 and immunohisto- chemistry. To analyze the cell survival and differentiation, cells were cultured in serum free medium supplemented with/without NGF. We performed the immunoprecipitation for the p53 induction of cells after ionizing radiation, and the FACS for the apoptosis of cells after the exposure of wortmanin. RESULTS: PC-12 cells which down-regulated AT gene (like ATM, AT mutated) showed decreased survival and ceased differentiation with NGF. Also, PC-12 (ATM) cells showed increased apoptosis with wortmanin and reduced or delayed p53 induction after ionizingradiation. CONCLUSION: Results obtained from these studies suggest that AT gene regulates survival and differentiation of PC-12 cells through PI3-kinase activity. It seems that apoptosis is induced by the inhibition of AT gene expression.
Apoptosis
;
Ataxia Telangiectasia
;
Calcium
;
Cell Survival
;
Chemistry
;
DNA
;
Gene Expression
;
Hypersensitivity
;
Immune System
;
Immunoprecipitation
;
MCF-7 Cells
;
Nerve Growth Factor
;
Phenotype*
;
Phosphatidylinositol 3-Kinases
;
Radiation, Ionizing