No abstract available.
Hearing* ; Humans ; Tinnitus*

No abstract available.
Otoacoustic Emissions, Spontaneous*

No abstract available.
Pregnancy*

No abstract available.

No abstract available.
Adult* ; Animals ; Humans ; Liver* ; Population Characteristics* ; Rats*

Hair takes a great role in featuring man's appearance and absence of hair can causes troubles in physical and psychological aspects. Many efforts have been made to treat male pattern baldness, including medical therapy and surgical correction, but there is not a definite and eternal method of treatment. Even though the diagnosis of male pattern baldness can be made with its characteristic clinical manifestations, histopathological study must be done for definite diagnosis. Author obtained biopsy material from the frontal progressive baldness area and the occipital non-baldness area with punch biopsy in 20 patients who were diagnosed to be Type II and III male pattern baldness according to the Norwood classification. A comparative study was done in the basis of histopathology using serial vertical section of the biopsy materia with the aid of light microscope and the results are as follows : 1. The average number of total hair in the frontal area was on third than that of occipital area and the number of anagen hair was less in the frontal area. The number of telogen hair in the frontal area was seven times more than that of occipital area. 2. The thickness of epidermis and dermis in the frontal area was thinner than that of occipital area. 3. The infiltration of inflammatory cells in the periadnexal field like blood vessels, hair follicles, sebaceous glands, eccrine glands was more prominent in the frontal area than in the occipatal area. 4. Perifollicular fibrosis and hypertrophy of arrector pilli muscle were more remarkable in the frontal area compared with that of occipital area. 5. There was no difference between the frontal and occipiral area in the number of lobules of sebaceous glands.
Alopecia* ; Biopsy ; Blood Vessels ; Classification ; Dermis ; Diagnosis ; Eccrine Glands ; Epidermis ; Fibrosis ; Hair ; Hair Follicle ; Humans ; Hypertrophy ; Male* ; Sebaceous Glands

No abstract available.
Female ; Humans ; Pregnant Women*

Rheumatoid arthritis (RA), which is frequently involved in the articulations of the hands and feet, is known to be related with inheritance. Dermatoglyphics, the patterns of ridges on the skin of the fingertips, palms, and soles, are mostly related with inheritance. The purpose of this study is to verify the possibility that dermatoglyphics are helpful for the diagnosis of RA. We attempted to compare the characteristics of the fingerprints, palmprints, and palm creases in 67 Korean RA patients (RA group) to those in 3, 216 normal Korean persons. In the RA group, the radial loop and whorl were more frequent whereas the arch and ulnar loop were less frequent. The total fingerprint ridges were more numerous and 11 palmprint D type was more frequent in the RA group. Also, the Simian and Sydney creases were more frequent and the total degree of palm crease transversality was lower in the RA group. In addition, a part of the dermatoglyphic characteristics of the Korean RA group were different from those of the Indian RA group. These results suggest that dermatoglyphics may be helpful in the diagnosis of Korean RA patients.
Arthritis, Rheumatoid* ; Dermatoglyphics* ; Diagnosis ; Foot ; Hand ; Humans ; Skin ; Wills

No abstract available.
Antibodies, Monoclonal* ; Herpesvirus 3, Human*

BACKGROUND: Various neuronal and glial factors which participate in neural differentiation, including neural cell adhesion molecule (NCAM), are upregulated in pathogenesis of temporal lobe epilesy (TLE).This study aimed to investigate hte effect of (R-)-N6-phenylisopropyladenosine (RPIA), an adenosine A1 receptor agonist, on the morphological alteration of NCAM immunoreactivity (IR) in limbic system of Kainic acid (KA)-induced epileptic rats. METHODS: Experiment animals were divided into control group, KA treatment only (10 mg/kg. i.p.)group, and RPIA pretreatment (100 microgram/kg. i,p, 10 min prior to injection of KA) group. Animals were sacrificed at 24 hours and 1 week after KA treatment. Luxol fast blue-cresyl violet stain for histopathological observation, and NCAM immunohistochemistry to study alteration of NCAM IR in limbic system were performed. RESULTS: Neuronal loss in CA1 and CA3areas of hippocampus, piridorm cortex, basolateral amygdala nucleus and lateral dorsal thalamic nucleus were induced by KA unjection, and thoes were reduced by RPIA pretreatment. Inrease of NCAM-IR was observed in interneurons of all hippocampal areas. except CA2 area, pirform cortex and basolateral amygdala nucleus at 24 hours after KA injection. and increased NCAM-IR was observed in cell membrane and processes of neuroglia, dentate granule cells and pyramidal cells in CA1 area of hippocampus. and neurons in piriform cortex, amygdala and lateral dorsal thalamic nucleus 1 week after KA injection, but those changes were milder than those at 24 hours after KA injection. RPIA pretreatment significantly reduced KA-induced NCAM-IR in hippocampal CA3, CA1 area, piriform cortex, amtgdala and lateral dorsal thalamic nucleus. CONCLUSION: We suggest that decrease of NCAM immunoreactivity is associated with neuprotective effects of RPIA on limbic system against KA neurotoxiciy.
Amygdala ; Animals ; Cell Membrane ; Epilepsy, Temporal Lobe ; Hippocampus ; Immunohistochemistry ; Interneurons ; Kainic Acid ; Lateral Thalamic Nuclei ; Limbic System ; Neural Cell Adhesion Molecules ; Neuroglia ; Neurons ; Pyramidal Cells ; Rats ; Receptor, Adenosine A1 ; Temporal Lobe ; Viola