1.Placental Transfer of Anti-H. influenzae Type b Specific IgG and Subclasses.
Soo Hee CHANG ; Moon Hwan LEE ; Pyoung Han HWANG ; Soo Chul CHO ; Jung Soo KIM
Journal of the Korean Pediatric Society 1995;38(12):1638-1644
No abstract available.
Immunoglobulin G*
;
Influenza, Human*
2.Analysis of the result and merit of computed tomography guided percutaneous needle aspiration biopsy of focal lung lesion.
You Song CHANG ; Kil Ho CHO ; Woo Mock BYUN ; Mi Soo HWANG ; Bok Hwan PRK
Yeungnam University Journal of Medicine 1993;10(1):127-134
Percutaneous needle biopsy of pulmonary lesion with use of fluoroscopic guidance is well estabilished as a diagnostic tool but limited by the small size and inaccessibility of certain lesions. However, percutaneous needle biopsy'has been used increasingly in relation to advance and the salty of smaller biopsy needle and new imaging modalities such as ultrasound and CT. CT, because of its characteristics of high resolution, allows tissue sampling with considerable safty from area that heretofore could not be visualized under fluoroscopy. The authors summarized 44 pulmonary lesions that underwent CT-guided transthoracic biopsy with fine-needle over a 14 month period and analyzed the sensitivity of PTNB. -CT-guided PTNB was done with 20 gauge or 22 gauge Westcott biopoy needle (Mann medical products, USA). A diagnosis was made in 27 of 44 cases (61%) including malignany in 19 of 24 cases and benignancy in 8 of 20 cases. The pulmonary mass lesions were located at the peripheral zone of the lung field in 33 cases and at the central zone in 11 cases. Complications were observed in 2 cases which were pneumothorax and hemoptysis each but specific therapy was not required The sensitivity of PTNB by one session was 61% (27/44). The sensitivity of malignancy was 79% (19/24) and benignancy was 40% (8/20). These results suggest the usefulness of PTNB using fine needles be increased in eariler diagnosis and improved staging of pulmonary nodular lesions without significant complications.
Biopsy
;
Biopsy, Needle*
;
Diagnosis
;
Fluoroscopy
;
Hemoptysis
;
Lung*
;
Needles*
;
Pneumothorax
;
Ultrasonography
3.A Case of Linear IgA Bullous Dermatosis.
Yoo Jung HWANG ; Hong Yoon YANG ; Chang Woo LEE ; Joong Hwan KIM
Annals of Dermatology 1993;5(1):51-55
This paper deals with a case of linear IgA bullous dermatosis (LABD). The patient was a 58-year-old woman who had multiple pruritic vesicles on the trunk, buttocks, thighs, tongue and buccal mucosa. A biopsy of a lesion revealed subepidermal vesicles. Direct immunofluorescence examination of the perilesional skin showed a linear deposition of IgA along the basement membrane zone (BMZ). Indirect immunofluorescence examination, using NaCl split skin as substrate, showed antiBMZ IgA antibodies bound only to the epidermal side. The skin lesions responded well to oral dapsone therapy.
Antibodies
;
Basement Membrane
;
Biopsy
;
Buttocks
;
Dapsone
;
Female
;
Fluorescent Antibody Technique, Direct
;
Fluorescent Antibody Technique, Indirect
;
Humans
;
Immunoglobulin A
;
Linear IgA Bullous Dermatosis*
;
Middle Aged
;
Mouth Mucosa
;
Skin
;
Thigh
;
Tongue
4.A Case of Linear IgA Bullous Dermatosis.
Yoo Jung HWANG ; Hong Yoon YANG ; Chang Woo LEE ; Joong Hwan KIM
Annals of Dermatology 1993;5(1):51-55
This paper deals with a case of linear IgA bullous dermatosis (LABD). The patient was a 58-year-old woman who had multiple pruritic vesicles on the trunk, buttocks, thighs, tongue and buccal mucosa. A biopsy of a lesion revealed subepidermal vesicles. Direct immunofluorescence examination of the perilesional skin showed a linear deposition of IgA along the basement membrane zone (BMZ). Indirect immunofluorescence examination, using NaCl split skin as substrate, showed antiBMZ IgA antibodies bound only to the epidermal side. The skin lesions responded well to oral dapsone therapy.
Antibodies
;
Basement Membrane
;
Biopsy
;
Buttocks
;
Dapsone
;
Female
;
Fluorescent Antibody Technique, Direct
;
Fluorescent Antibody Technique, Indirect
;
Humans
;
Immunoglobulin A
;
Linear IgA Bullous Dermatosis*
;
Middle Aged
;
Mouth Mucosa
;
Skin
;
Thigh
;
Tongue
5.Radiologic findings of mediastinal fibromatosis.
You Song CHANG ; Jae Ho CHO ; Kil Ho CHO ; Mee Soo HWANG ; Bok Hwan PARK
Yeungnam University Journal of Medicine 1991;8(2):217-221
The fibromatosis is a rare timorous with local invasion, but is not metastasized distantly. This term should not be applied to nonspecific reactive fibrous proliferations that are part of an inflammatory process of are secondary to injury of hemorrhage and have no tendency toward growth or recurrence. It arises principally from the connective tissue of muscle and overlying fascia or aponeurosis (musculoaponeurotic fibromatosis), and chiefly affects the muscle of shoulder, pelvic girdle, and extremity. The term 'aggressive fibromatosis' is also employed to describe this disease, but it is impossible to predict the clinical course in the individual case. The fibromatosis arising in the mediastinum is very rare, and the report about it is nearly absent. The plain radiography shows merely mass with soft tissue density. The CT demonstrates a poorly defined homogenous or heterogeneous mass, isodense with skeletal muscle on precontrast-images, and slightly hyperdense to muscle on postcontrast-scan. Accurate delineation between the tumor & surrounding tissue is vague or frequently impossible. The authors experienced one case of the mediastinal fibromatosis recently and report the case with review of concerned literature.
Connective Tissue
;
Extremities
;
Fascia
;
Fibroma*
;
Hemorrhage
;
Indonesia
;
Mediastinum
;
Muscle, Skeletal
;
Radiography
;
Recurrence
;
Shoulder
6.The Effect of Oral Ketoconazole in Dermatophytosis.
Jahng Won JUNN ; Do Hun HWANG ; Chang Hoon KWAK ; Jae Hong KIM ; Joong Hwan KIM
Korean Journal of Dermatology 1984;22(1):16-21
Seventeen volunteers with cutaneous dermatophytosis were enrolled in a clinical trial to evaluate the effectiveness of oral ketoconazole. The group included six patients with tinea cruris(6 malcs), four with tinea corporis, including one with tinea faciai, (3 males, 1 female), three with tinea versicolor(3 males) and four with tinea capitis(3 males, 1 female). The oral ketoconazole was taken within 10 minutes after a meal. The patients under the age of 10 received 100mg of ketoconazole per day, whereas those aged over 11 received 200mg of ketoconazole until the skin lesions are cured. Seventeen patients had complete clinical and mycologic cure, one responded clinically. It required one to four weeks to become culturally negative for tinea cruris, four to seven weeks for tinea corporis, three to eight weeks for tinea capitis. For tinea versicolor it required three to five weeks to become negative by scotch tape method. Adverse reactions to ketoconazole were absent and no patients required discontinuation of the drug. The results indicate that ketoconazole is a safe and effective drug for the treatment of dermatophytosis.
Humans
;
Ketoconazole*
;
Male
;
Meals
;
Skin
;
Tinea Capitis
;
Tinea Versicolor
;
Tinea*
;
Volunteers
7.Treatment of Traumatic Carotid-Cavernous Fistulas using Debrun's Detachable Balloons.
Sang Jin LEE ; Son Yong KIM ; Mi Soo HWANG ; Jae Chun CHANG ; Bok Hwan PARK
Yeungnam University Journal of Medicine 1989;6(2):91-101
The goal of therapy in patients with traumatic carotid-cavernous fistulas is to occlude the fistula preferably while maintaining the carotid blood flow. Since the introduction of the concepts of detachable balloon technique to occlude arteriovenous fistulas, the technique has become the treatment of choice in the management of traumatic carotid-cavernous fistulas. The major symptoms of traumatic CCFs are (1) pulsating exophthalmos, (2) orbital and cephalic bruit and murmur, (3) headache, (4) chemosis, (5) extraocular palsies, and (6) visual failure. Traumatic CCFs are combined with multiple associated lesion. We tried the occlusion of fistulas using Goldvalve balloons in 8 consecutive cases of traumatic CCF and the result of our experience is reported. Transarterial approach with manually-tied latex balloons is tried in all cases and the fistulas was successfully occluded in all cases. In 5 cases, the internal carotid artery was preserved and the arterial lumen was occluded along with fistula opening in cases. In one case, surgical ligation was done because of symptoms recurred and incomplete occlusion of fistula. We experienced hemiparesis as a major complication in one case during occlusion tolerance test, which was remitted spontaneously. The results of Debrun balloon treatment were relatively excellent. We consider that the first choice of treatment of traumatic CCF is occlusion of the fistula by a detachable balloons.
Arteriovenous Fistula
;
Carotid Artery, Internal
;
Exophthalmos
;
Fistula*
;
Headache
;
Humans
;
Latex
;
Ligation
;
Orbit
;
Paralysis
;
Paresis
8.Screening for In Vitro Antifungal Activity of Soil Bacteria Against Plant Pathogens.
Sung Hwan CHANG ; Jung Yeop LEE ; Ki Deok KIM ; Byung Kook HWANG
Mycobiology 2000;28(4):190-192
Antifungal bacteria for biological control of plant diseases or production of novel antibiotics to plant pathogens were isolated in 1997 from various soils of Ansung, Chunan, Koyang, and Paju in Korea. Sixty-four bacterial strains pre-screened from approximately 1,400 strains were tested on V-8 juice agar against eight plant pathogenic fungi using in vitro bioassay technique for inhibition of mycelial growth. Test pathogens were Alternaria mali, Colletotrichum gloeosporioides, C. orbiculare, Fusarium oxysporum f. sp. cucumerinum, F. oxysporum f. sp. lycopersici, Magnaporthe grisea, Phytophthora capsici, and Rhizoctonia solani. A wide range of antifungal activity of bacterial strains was found against the pathogenic fungi, and strain RC-B77 showed the best antifungal activity. Correlation analysis between inhibition of each fungus and mean inhibition of all eight fungi by 64 bacterial strains revealed that C. gloeosporioides would be best appropriate for detecting bacterial strains producing antibiotics with potential as biocontrol agents for plant pathogens.
Agar
;
Alternaria
;
Anti-Bacterial Agents
;
Bacteria*
;
Biological Assay
;
Chungcheongnam-do
;
Colletotrichum
;
Fungi
;
Fusarium
;
Gyeonggi-do
;
Korea
;
Magnaporthe
;
Mali
;
Mass Screening*
;
Phytophthora
;
Plant Diseases
;
Plants*
;
Rhizoctonia
;
Soil*
9.Immunohistochemical study on the formation of germinal centers in the spleen of mouse injected with sheep red blood cells.
Wang Jae LEE ; Yong Hwan CHUNG ; Douk Ho HWANG ; Ka Young CHANG
Korean Journal of Anatomy 1993;26(1):50-64
No abstract available.
Animals
;
Erythrocytes*
;
Germinal Center*
;
Mice*
;
Sheep*
;
Spleen*
10.Clinical Behavior of Geriatricians Regarding Periodic Screening for Gastro-intestinal Cancers in Older Adults.
Hwan Sik HWANG ; Chang Won WON ; Dong Ho LEE
Journal of the Korean Geriatrics Society 2008;12(1):35-41
BACKGROUND: A questionnaire for geriatricians regarding their clinical practice of periodic gastro-intestinal cancer screening was developed. METHODS: The survey was administered to geriatricians participating in the 2007 Korean Geriatrics Society meeting at Busan, Korea. RESULTS: 162 completed the questionnaire. Average age of respondents was 46 years. Background specialty included family medicine(24%), internal medicine(22%), obstetrics and gynecology(9%), and general surgery(8%). 90% of geriatricians recommend screening for colorectal cancer in their practice. They recommend a colonoscopy if fecal occult blood test is positive(53%) or colonoscopy(31%). On average, they recommend screening for colorectal cancer every 2.5 years. Screening for colorectal cancer is recommended to those 75-79 years(33 %), 70-74 years(24%), and 65-69 years(24%). 94% of respondents recommend screening for stomach cancer in their practice. They recommend gastrofiberoscopy(95%) or upper GI series(5%). On average, screening is recommended every 1.5 years. Screening is recommended to those aged 75-79 years(34%), 70-74 years(19%), and 65-69 years(22%). CONCLUSION: Most geriatricians prefer endoscopic examinations for screening for GI cancer. They recommend, on average, screening for colorectal cancer and stomach cancer every 2.5 and 1.5 years, respectively. Most geriatricians recommend GI cancer screening to those aged 75-79 years.
Adult
;
Aged
;
Colonoscopy
;
Colorectal Neoplasms
;
Surveys and Questionnaires
;
Early Detection of Cancer
;
Geriatrics
;
Humans
;
Mass Screening
;
Obstetrics
;
Occult Blood
;
Stomach Neoplasms