Orthopaedic wire has been used widely as a good internal fixator in cases of fracture, the ligament reconstruction, and for the stabilization of cervical spine. But if it is used inappropriately, a wire can be easy to fail by elongation, untwisting, or breakage. Among them, the most common failure of wire is breakage. To clarify the mechanism and the causes of wire failure, the authors analysed serial roentgenograms and scanning electronmicroscopic findings of broken wire in total 13 cases, which were experienced at the department of orthopaedic surgery, St. Mary's Hospital, Catholic University Medical College From January 1981 to December 1987. The results obtained were as follows :1. The mechanism of wire failure were classified into the 4 types ; minor continual flexing motion in 6 cases, repeated minor back and forth torsion in 1 case, tension failure in 2 cases and combined type in 4 cass. 2. The causes of wire failure were in appropriate use and inadequte application, a lack of s ufficient mechanical strength, micromotion due to inadequate postoperative imm obilization, early mobilization before tissue healing as well as certain injuries to the wire during handling in operation.
Early Ambulation ; Fatigue ; Internal Fixators ; Ligaments ; Spine

No abstract availble.

No abstract available.
Ammonium Compounds* ; Ammonium Sulfate* ; Animals ; Bromodeoxyuridine* ; CHO Cells* ; Chromosome Aberrations* ; Cricetinae ; Humans ; Siblings* ; Sister Chromatid Exchange*

Thirty-five cerebello-pontine angle lesions were diagnosed with simple skull X-ray, CT, and angiography atSeoul National University Hospital from Sept. 1978 through Aug. 1982. The radiographic findings were analysed withemphasis on the differential points of CT among the major three cerebello-pontine angle tumors; acousticneurinoma, meningioma and epidermoid. The results are as follows; 1. Among the 35 cases of cerebello-pontine anglelesions, 19 cases were acoustic neurinoma. 4 cases miningioma, 4 cases epidermoid, 2 cases metastasis, 1 caseschoroid plexus papilloma, 1 case arteriovenous malformation, and 3 cases intra-axial posterior fossa tumors. 2.The characteristic radiographic findings of acoustic neurinoma were windening of internal auditory canal, petrousbone erosion, posterior extension of tumor at the level of internal autidory canal, hypo or isodense mass onpre-contrast CT with high enhancement after intravenous contrast infusion, and cystic change within the mass. 3.Meningioma shows anterior extenstion of the lesion at the level of internal auditory canal, broad base and obtuseangle sign of the lesion with petrous bone, hyperdense mass on precontrast CT. with highly homogeneous enhancementafter intravenous contrast infusion. 4. Epidermoid characteristically shows hypodense mass on precontrast CT withno change after intravenous contrast infusion. 5. The differential points of the major 3 cerebello-pontine tumorswere bone change, mass location, attenuation , degree of attachment to petrous bone, and cystic change.
Angiography ; Arteriovenous Malformations ; Infratentorial Neoplasms ; Meningioma ; Neoplasm Metastasis ; Neuroma, Acoustic ; Papilloma ; Petrous Bone ; Skull

Wide resection is an acceptable alternative to amputation for the management of primary sarcomas of the long bones or pelvis. The resected bone can be debrided of gross tumor tissue, autoclaved, and than replaced to reconstruct the limb anatomically. The procedure can be combined with prosthetic reconstruction of adjacent joints with sufficient strength to allow early unprotected weight-bearing. We had an experience of a large segmental defect in the shaft of the humerus after wide resection due to.a low grade malignant chondrosarcoma without extension to the surrounding soft tissues and this case had been managed by reimplantation after autoclaving the locally resected segment and autogenous iliac bone graft with a sound union and the favorable functional outcomes. So we are reporting this case with bibliographic reviews as a possible method of reconstruction for the management of the segmental defect which was produced by a local resection for a low grade malignancy.
Amputation ; Chondrosarcoma ; Extremities ; Humerus ; Joints ; Methods ; Pelvis ; Replantation ; Sarcoma ; Transplants ; Weight-Bearing

No abstract available.
Lymphoma, T-Cell, Cutaneous*

No abstract available.

PURPOSE: To analyze contrast-enhancement pattern of stomach cancer on dynamic MRI and to verify the efficacy of intravenous contrast agent in the evaluation of stomach cancer. MATERIALS AND METHODS: Twelve patients with proven stomach cancer underwent dynamic MRI, By using 1.0T scanner, we obtained precontrast FLASH images, and 30, 60, 90 second delay FLASH images after intravenous contrast injection. All patients ingested on liter of water and had intramuscluar injection of Buscopan just before MR study. For quantitative analysis we measured signal to noise ratio (S/N) of stomach cancer on each image, and signal difference to noise ratio (SD/N) between cancer and intraluminal fluid, cancer and the pancreas. For qualitative analysis two radiologists evaluated lesion conspicuity on each image by grading system(grade 0, 1, 2, 3: poor, fair, good, excellent). RESULTS: S/N of stomach cancer increased gradually by time(precontrast, 30, 60, 90 second delay:38.7, 42.5, 57.4, 65.7). SD/N between cancer and intraluminal fluid significantly increased after contrast enhancement(1.24, 25.01, 39.30, 45.89). SD/Ns between cancer and the pancreas were 10.5, 9.33, 9.99, 10.66 respectively. In qualitative analysis, precontrast images were better than postcontrast images for delineation of stomach cancer, Postcontrast images showed clear endo-luminal side of stomach cancer, but outer margin of stomach cancer was more distinct on precontrast images. CONCLUSION: Precontrast MR images are better than postcontrast MR images in the depiction of stomach cancer. Intravenous contrast agent is not imperative in the evaluation of stomach cancer.
Butylscopolammonium Bromide ; Humans ; Magnetic Resonance Imaging* ; Noise ; Pancreas ; Signal-To-Noise Ratio ; Stomach Neoplasms* ; Water

In case of limbitis, cytokines secreted by PMNs might inhibit the function of corneal epithelial stem cells located at the limbal basal cell layer. The purpose of this study was to examine whether PMNs factor affected stem cells (SC). PMNs obtained from the peritoneal cavity of rabbits after 0.2% glycogen stimulation incubated in DMEM at 37 degrees C for 24 hours. PMNs factor was obtained from the medium using dialysis. The death or inhibition of growth of rabbit corneal epithelial cells (CE) by PMNs factor was studied in vitro. PMNs factor and PBS as a control were injected into the limbal region for clinical evaluation and histopathologic study. ID 50 of PMNs factor for cultured CE was equal to the amount of polypeptide produced by 1.29 x 0 (7) PMNs. Cultured rabbit CE shrank and began to die 24 hours after exposure to PMNs factor. Abnormal findings were observed 5 days and 8 months after injection of PMNs factor at the limbus by light and electron microscopy. Clouding, defect, and vascularization of CE were noted several months after injection of PMNs factor. PMNs in limbitis may damage corneal epithelial stem cells and cause epithelial instability of the cornea.
Cornea ; Cytokines ; Dialysis ; Epithelial Cells ; Glycogen ; Microscopy, Electron ; Neutrophils* ; Peritoneal Cavity ; Rabbits ; Stem Cells*

Ulcerative colitis (UC) is a chronic inflammatory disease of the colon that is confined to the mucosa and submucosa. The diagnosis is based on a combination of clinical, endoscopic, and histological characteristics, as no single finding is diagnostic for UC. The most important symptoms of UC are rectal bleeding, urgency, and diarrhea. The typical endoscopic feature of UC is continuous, circumferential, and symmetric colonic involvement. The inflammation involves the rectum and may extend proximally. The mucosal biopsy shows crypt architecture distortion, mixed inflammatory cell infiltration in the lamina propria, increased plasma cells near the crypt bases, and basal lymphoid aggregates. In addition, many diseases, such as infectious causes, should be excluded from the differential diagnosis. Finally, an evaluation of the extent and severity of UC is important in determining how to treat patients.
Biopsy ; Colitis, Ulcerative ; Colon ; Colonoscopy ; Diagnosis, Differential ; Diarrhea ; Hemorrhage ; Humans ; Inflammation ; Mucous Membrane ; Plasma Cells ; Rectum ; Ulcer