1.Degenerative Cervical Myelopathy: Pathophysiology and Current Treatment Strategies
Sung Hoon CHOI ; Chang-Nam KANG
Asian Spine Journal 2020;14(5):710-720
Chronic compression or ischemia of the spinal cord in the cervical spine causes a clinical syndrome known as cervical myelopathy. Recently, a new term “degenerative cervical myelopathy (DCM)” was introduced. DCM encompasses spondylosis, intervertebral disk herniation, facet arthrosis, ligamentous hypertrophy, calcification, and ossification. The pathophysiology of DCM includes structural and functional abnormalities of the spinal cord caused by static and dynamic factors. In nonoperative patients, cervical myelopathy has a poor prognosis. Surgical treatments, such as anterior or posterior decompression accompanying arthrodesis, arthroplasty, or laminoplasty, should be considered for patients with chronic progressive cervical myelopathy. Surgical decompression can prevent the progression of myelopathy and improve the neurologic status, functional outcomes, and quality of life, irrespective of differences in medical systems and sociocultural determinants of health. The anterior surgical approach to the cervical spine has the advantage of removing or floating the intervertebral disk, osteophytes, and ossification of the posterior longitudinal ligament that compress the spinal cord directly. The posterior surgical approach to the cervical spine is mainly used for multisegment spinal cord compression in patients with cervical lordosis. In this review article, we addressed the pathophysiology, clinical manifestations, differential diagnosis, and treatment options for DCM.
2.Comparative study of survival rate of gastric cancer patients according to TNM classification.
Chang Hoon LEE ; Kyung Hoon CHOI ; Jae Kwan SEO
Journal of the Korean Cancer Association 1993;25(2):170-175
No abstract available.
Classification*
;
Humans
;
Stomach Neoplasms*
;
Survival Rate*
3.Effect of Extracorporeal Shock Wave Lithotripsy of Caliceal Stone according to the Location of the Stone .
Chang Hoon CHOI ; Ho Cheol SEO ; Jong Sung KIM
Korean Journal of Urology 1998;39(2):138-140
PURPOSE: Lower caliceal stones treated with ESWL do fail to pass more frequently than middle or upper caliceal stones. We analyzed the results of ESWL of renal caliceal stones according to the location of calix. MATERIALS AND METHODS: We reviewed the stone-free rate in 119 caliceal stone patients treated with 3rd generation lithotriptor, EDAP LT-02 according to the caliceal location of the stone. Location of the stones were upper calix in 30, middle calix in 30, and lower calix in 59 patients. RESULTS: Stone-free rate was 90.0%(27/30 patients) in middle caliceal stones, 74.6%(44/59 patients) in lower caliceal stones, and 66.7%(20/30 patients) in upper caliceal stones. CONCLUSIONS: Stone-free rate of lower caliceal stones is higher than upper caliceal stones.
Humans
;
Lithotripsy*
;
Shock*
4.Cutaneous Manifestations of Carbon Monoxide Poisoning.
Jung Bock LEE ; Kyung Hoon CHANG ; Il Saing CHOI
Korean Journal of Dermatology 1983;21(3):279-286
Carbon monoxide is colorless, oolorless, tasteless and non-irritating gas produced by the incomplete combustion of carbonaceous rnaterial. It combines with hemoglobin and displaces oxygen because the affinity of hemoglobin for carbon monoxide is two hundred times greater than oxygen. Symptoma and signs of carbon monoxide poisoning include headache, nausea, vomiting, dizziness, collapse, unconsciousness, blindness, convulsion, coma and skin lesions. Recently we have observed seven patients with carbon monoxide poisoning who expressed cutaneous syrnptoms. In this work we investigated the pathogenesis of cutaneous manifestations of carbon monoxide poisoning through clinical, histologic and electronmicroscopic study. The results are summarized as follows: 1. Mental states of the patients were comatose in two, Semicomatcse in two, stuporous in two, and drowsy in one patient. In routine laboratory tests, we observed elevated blood sugar in six, elevated sorum creatinine phosphokinase in four and abnormal findings in urinalysis in all patients. 2. Cutaneous lesions were vesicobullae, plaque or swelling, erythema, gangrene and 'ulceration in order of frequency and located in the dependent areas in six caies. 3. Histopathologically, the sites of the bullae were subepidermal in four cases and intraepidermal in. one case and there was one case with ulceration. 4. In electronmicroscopic findings, secretory and ductal cells showed degenerative
Blindness
;
Blood Glucose
;
Carbon Monoxide Poisoning*
;
Carbon Monoxide*
;
Carbon*
;
Coma
;
Creatinine
;
Dizziness
;
Erythema
;
Gangrene
;
Headache
;
Humans
;
Nausea
;
Oxygen
;
Seizures
;
Skin
;
Stupor
;
Ulcer
;
Unconsciousness
;
Urinalysis
;
Vomiting
5.Clinical experience of multiple valve replacement.
Chang Hoon CHO ; Sae Young CHOI ; Chang Kwon PARK ; Kwang Sook LEE ; Young Sun YOO
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(11):1346-1353
No abstract available.
6.Serum and urine potassium changes during, and after extracorporeal circulation in open heart surgery.
Chang Hoon JO ; Sae Young CHOI ; Chang Kwon PARK ; Kwang Sook LEE ; Young Sun YOO
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(1):17-22
No abstract available.
Extracorporeal Circulation*
;
Heart*
;
Potassium*
;
Thoracic Surgery*
7.Coronary Intervention of Cardiogenic Shock in Acute Myocardial Infarction.
Jae Woong CHOI ; Chang Sup SONG ; Chin Woo IMM ; Tae Hoon AHN ; In Seog CHOI ; Ik Kyun SHIN ; Young Hoon PARK
Korean Circulation Journal 1996;26(2):449-454
BACKGROUND: Despite improvement of mortality in acute myocardial infarcrtion, high mortality rate associated with cardiogenic shock remains essentially unchanged. We have reviewed our result of coronary intervention in 15 patients and found relative survival advantage. METHODS: Between Sep. 1992 and Aug. 1995, 15 consecutive patients(M. 10, F. 5) with cardiogenic shock in acute myocardial infarction were treated with coronary intervention using ballon PTCA. IABP was inserted in all patients prior to PTCA. RESULTS: 1) Most commonly found infarct related artery was left anterior descending artery(11) followed by right coronary artery(3) and left main coronary artery(1). 2) Successful reperfusion rate was 86.7%(13/15), and in-hospital mortality rate was 26.7%(4/15). 3) In-hospital mortality was higher in elderly patients compared with less than 70yaer old patients(0%(0/11)vs. 75.0%(3/4)(P < 0.05). 4) Mortality rate was lower in single vessel disease than multivessel disease(11.1%(1/9) vs. 50%(3/6) p<0.05). CONCLUSION: Although this study is uncontrolled, the date suggest that urgent coronary intervention for improving coronary perfusion may reduce mortality of acute myocardial infarction complicated by cardiogenic shock, particularly with single vessel disease and young age group.
Aged
;
Arteries
;
Hospital Mortality
;
Humans
;
Mortality
;
Myocardial Infarction*
;
Perfusion
;
Reperfusion
;
Shock, Cardiogenic*
8.Tracheal homografts in the canine.
Hong Shik CHOI ; Eun Chang CHOI ; Kwang Moon KIM ; Nam Hoon CHO ; Kee Hyun PARK
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(2):304-315
No abstract available.
Allografts*
9.A Case of Limb-Body Wall Complex.
Chang Hoon SONG ; Sang Joon CHOI ; Hyung Gyun ROH ; Kyung LEE ; Hyuk JUNG
Korean Journal of Perinatology 1998;9(1):70-74
Limb-Body Wall complex is a complicated with the essential features of neural-tube defects, body-wall disruption, and limb abnormalities. This complex should be distinguished from other body-wall defects including omphalocele and gastroschisis since the prognosis for limb-body wall is uniformly poor. We have experienced one case of limb-body wall complex in a 22-year-old primigravida, which is presented with a brief review of the literature.
Extremities
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Gastroschisis
;
Hernia, Umbilical
;
Humans
;
Prognosis
;
Young Adult
10.MRI fidings of primary intracranial lymphoma in immunologically normal patients.
Ho Chul KIM ; Kee Hyun CHANG ; Sang Hoon CHA ; Moon Hee HAN ; Choong Gon CHOI
Journal of the Korean Radiological Society 1993;29(4):613-620
Magnetic resonance (MR) images of 14 consecutive patients with pathologically proven primary intracranial lymphoma were reviewed. All patients had a brain MR imaging before any treatment and were immunologically competent. MR images were acquired using 2.07 (n= 6) or 0.57 (n= 8) machine. The MR images were reviewed regarding the location, multiplicity, size, signal intensity, margin, shape, and the extent of surrounding edema of the lesion. Seven patients had multiple lesions, 2 to 4 in number. A total of 26 lesions was found; 25 were parenchymal lesions and one was dural lesion. The location of tumor was either central (r= 11) or peripheral (n= 14). The size of tumor was variable ranging from 0.6cm to 6.0cm in its maximal diameter. The tumors were isointense (n= 19) or hypointense (n= 7) relative to gray matter on T1-weighted images, isointense (n= 24) or hyperintense (n=2) on proton-density weighted images, and isointense (n= 21) or hyperintense (n= 5) on 78-weighted images. On gadolinium-enhanced T1-weighted images of 13 patients strong enhancement was seen in 22 of 23 lesions. Nineteen lesions showed smooth, well-defined margin, whereas remaining 7 lesions showed irregular, ill-defined margin. The shape of the tumor was diverse; round of ovoid (n= 15), lobulated (n= 9), or short linear (n= 2). These results suggest that one should consider the diagnosis of CNS lymphoma in cases with single or multiple masses that abut CSF space and show iso-or similar intensity to gray matter with strong enhancement on MR images.
Brain
;
Diagnosis
;
Edema
;
Gray Matter
;
Humans
;
Lymphoma*
;
Magnetic Resonance Imaging*