No abstract available.
Animals ; DNA* ; LLC-PK1 Cells* ; Swine

No abstract available.

The object of this study was 336 Korean patients with degenerative arthritic knees and 1000 Koreans with normal knees who had visited the department of orthopaedic surgery of Hanyang University hospital during the period fmm January, 1980 to June, 1981. The purpose of this study was to investigate the changes of tibio-femoral angles and metaphysealdia physeal angles in response to the degenerative changes of the knees. By the roentgenogram, tibio-femoral angles and metaphyseal-diaphyseal angles were measured and those angles were analized statistically. The results were as follows 1. In young age group, the incidence of the degenerative arthritic knees was more frequent in male than in female. However, in the middle and older age groups, the incidence was higher in female than in male. 2. The mean value of tibio-femoral angle of the degenerative arthritic knees was −3.41°±0.22. It was about 1° varus compared with the normal mean value of −4.46°±0.27. The mean value of tibio-femoral angle in normal Korean was reduced appmximately 3°±5°valgus compared with the Westem normal peoples: 3. In general, the valgus tendency appeared a little more in the knees of female than in those of male. 4. The varus tendency was in pmportion to the degree of the aggrevation of the degenerative arthritis in the knees. 5. The mean value of metaphyseal-diaphyseal angle in normal Korean was 3.53°±0.24. It was 3°–4° varus compared with the Western normal peoples. 6.The varus was increased more in the standing position, in the state of weight bearing position, than in the supine position.
Female ; Humans ; Incidence ; Knee ; Male ; Osteoarthritis ; Posture ; Supine Position ; Weight-Bearing

No abstract available.
Adult* ; Humans ; Molecular Epidemiology* ; Oxalobacter formigenes* ; Seoul*

PURPOSE: To evaluate the efficacy of combined treatment of metallic biliary stent placement and radiotherapy in malignant biliary obstruction. MATERIALS AND METHODS: Between January 1992 and February 1994, 22 patients with malignant biliary obstruction were treated with metallic biliary stent placement and radiotherapy. The causes of the obstruction included cholangiocarcinoma(n=14), gallbladder carcinoma(n=4), colon cancer(n=2), pancreatic head cancer (n=1), and stomach cancer(n=1). According to the sites of obstruction level, patient were divided into 2 groups; hilar obstruction(n=18) and common bile duct obstruction(n=4). The patients received dose of 45 Gray/18 fraction by external radiotherapy and 20Gy/8f by high dose rate brachytherapy with iridium--192 source through percutaneous transhepatic biliary drainage(PTBD) catheter. The duration of stent patency after placement, survival period and survival rate by Kaplan Meier method were calculated in dead and alive patients, respectively. RESULTS: In all 22 patients, the duration of stent patency was 5.5(1.3--18.5)months. Survival periods after stent placement and PTBD were 5.3(2.0--8.5 )months and 7.9(4.0--14.7)months respectively in 9 dead patients and 7.7(1.3--21.0)months and 9.5(2.3--23.0)months in 13 alive patients. In all 22 patients, the survival rates in 6, 12 and 18 months were 78.9%, 47.5 % and 35.6 %, respectively. CONCLUSIONS: The results with combined metallic biliary stent placement and radiotherapy for the palliative treatment of malignant biliary obstruction in this study was more favorable, as compared with those of the other authors with only metallic biliary stent placement.
Brachytherapy ; Catheters ; Colon ; Common Bile Duct ; Gallbladder ; Head and Neck Neoplasms ; Humans ; Palliative Care ; Radiotherapy* ; Stents* ; Stomach ; Survival Rate

Free dorsalis pedis flap transfers were performed in twelve cases at the Department of Orthopaedic Surgery of Hanyang University Hospital from January, 1980 to December, 1983. The result were summerized as followings; 1. Among twelve cases of the free dorsalis pedis flap transfer, neurovascular flap transfers were performed in nine cases and tendocutaneous flap transfers in five cases. 2. In all cases the textures of flaps were improved and the bulky subcutaneous fat tissues were shrunk gradually, so cosmetically good results were obtained. 3. Temperature, pain, protective and touch sensations were retained or restored by preservation of sensory nerve. 4. Free dorsalis pedis flap transfer has many advantages compared to conventional skin grafts, such as shorter therapeutic time, lesser physical or economic demands and primary covering to vital organ. 5. In injured hands, the application of free dorsalis pedis flap transfer including long extensor tendons of foot has been shown the excellent clinical result in the point of functional and cosmetic effect in dorsum of hand, as transferring simultaneously free tendon and skin flap. 6. Free dolis pedis flap transfer needs abundant experiences, meticulous microvascular technique and anatomic knowledge.
Clinical Study ; Foot ; Hand ; Microsurgery ; Sensation ; Skin ; Subcutaneous Fat ; Tendons ; Transplants

The effect of acetabular augmentation with bone graft was reviewed in 12 patients with acetabular deficiency in total hip arthroplasty, performed between 1981 and 1984 at Hanyang University Hospital. Follow-up ranged from 12 to 18 months and averaged 23.3 months. Follow-up radiographs were analyzed. Based on radiography, all grafts were regarded as incorporated and equally successful with autogenous and allograft bone. Long-term follow-up evaluation revealed no evidence of progressive radiolucency or graft resorption. There was one sciatic nerve palsy after operation but recovered at 11 months later.
Acetabulum ; Allografts ; Arthroplasty, Replacement, Hip ; Follow-Up Studies ; Humans ; Radiography ; Sciatic Neuropathy ; Transplants

PURPOSE: Nanobacteria have been reported to induce various pathologic calcifications like atherosclerosis and nephrolithiasis, and they do so by forming an apatite envelope, however, this concept is still controversial. We tried to elucidate whether nanobacteria might be related with urinary calcium stone by performing comparative study. MATERIALS AND METHODS: This study included 38 urinary stone patients who were proved to have calcium-containing stones and 37 healthy adults without urinary stone disease as controls. The subjects' age and gender were well matched between both groups. For the detection of nanobacteria, the serum and urine of all subjects were collected and western blotting for the samples was performed. RESULTS: There was no significant difference in the positive rate of nanobacteria from the serum samples between stone and control groups (52.6% vs 48.6%, respectively, p=0.465). But on the urine samples, the stone group showed a significantly higher positive rate than the control group (71.1% vs 21.6%, respectively, p<0.05). CONCLUSIONS: Nanobacteria might have a relation with urinary calcium stone disease.
Adult ; Atherosclerosis ; Bacteria ; Blotting, Western ; Calcifying Nanoparticles* ; Calcium* ; Humans ; Nephrolithiasis ; Urinary Calculi ; Urolithiasis

A review of 234 patients with cervical cancer during the last 5 years was undertaken to evaluate the efficacy of routine cystoscopic examination in staging cervical cancer. Cystoscopic abnormalities suggesting bladder invasion of the cervical cancer were found in none of the 127 patients with clinical stage 1 and 65 patients with clinical stage 2. In 7(22.6%) out of 31 patients with clinical stage 3 and in 4(80%) out of 5 patients with clinical stage 4. markedly bullous edema and hyperemia suggesting suspicious bladder invasion was identified on cystoscopy. Mucosal biopsy was done in 5 or them which revealed no pathologic invasion. Incidentally found transitional cell carcinoma was found in one patient. From these observations, it can be concluded that routine cystoscopy is not recommended in cervical cancer with clinical stage 1 and 2, and is indicated only in clinical stage 3 or greater.
Biopsy ; Carcinoma, Transitional Cell ; Cystoscopy* ; Edema ; Humans ; Hyperemia ; Urinary Bladder ; Uterine Cervical Neoplasms*

OBJECTIVES: The aim of this study is to confirm the clinical and histopathologic findings of ovarian tumors and determine the malignancy before operation. It will attribute to early diagnosis, determining direction of treatment and improving prognosis of malignant ovarian tumor. METHODS: Seven hundred sixty-five patients who had an operation for ovarian tumors in the department of Obstetrics and Gynecology of Gachon University Gil Medical Center from April 2007 to December 2009 were enrolled as subjects. A retrospective analysis of age, parity, menopausal status, preoperative CA 125, histology, ultrasound, and treatment method was done. RESULTS: 1. Among benign ovarian tumors, endometrial cyst (211 cases, 30.1%) was most common and had the highest preoperative CA 125 (76.07 U/mL). 2. Among borderline ovarian tumors, mucinous type (16 cases, 62.5%) was most common, but preoperative CA 125 was higher in serous type (144.38 U/mL) than mucinous type (82.59 U/mL). 3. Among malignant ovarian tumors, serous adenocarcinoma (14 cases, 29.8%) was most common, and undifferentiated carcinoma had the highest preoperative CA 125 (500.0 U/mL). 4. The preoperative CA 125 showed a tendency to increase in relation to stage in malignant ovarian tumors. 5. Age, preoperative CA 125, menopausal status and ultrasound finding were identified as discriminating factors for malignancy and relative risk of them were 7.19, 7.90, 5.56 and 61.43, respectively. CONCLUSION: Using the combination of age, menopausal status, preoperative CA 125 and ultrasound to diagnose ovarian tumors before the operation will be a help to early diagnosis and determining the treatment and improve prognosis.
Adenocarcinoma ; CA-125 Antigen ; Carcinoma ; Early Diagnosis ; Female ; Gynecology ; Humans ; Mucins ; Obstetrics ; Parity ; Prognosis ; Retrospective Studies