1.Growth and Development in Adolescence.
Journal of the Korean Pediatric Society 2003;46(Suppl 3):S462-S475
No abstract available.
Adolescent*
;
Growth and Development*
;
Humans
2.A Case of Cloverleaf Skull; Kleeblattschael Syndrome.
Chang Hyon YANG ; Kyu Earn KIM ; Chang Ho HONG
Journal of the Korean Pediatric Society 1987;30(4):456-460
No abstract available.
Skull*
3.Antibiotic loaded Plaster of Paris as a Prevention of Experimental Osteomyelitis in Rats
Chang Ju LEE ; Won Ho CHO ; Sung Kee CHANG ; Ho Guen CHANG ; Jae Hong KIM
The Journal of the Korean Orthopaedic Association 1989;24(5):1479-1485
Plaster of Paris is an effective ancillary treatment in the surgery of infected cavities in bone. It is well tolerated and spontaneously absorbed over the period of weeks to months, being replaced by bone of normal architecture. When the antibiotics incorporated into plaster of Paris, the antibiotics are capable of prolonged local release in bactericidal concentrations. Therefore it is proposed that antibiotics loaded plaster of Paris might be a simple adjuvant technique after good surgical debridement for the treatment of bone infection. The authors carried out an experiment to study the effect of plaster of Paris containing antibiotics for a prevention of experimental osteomyelitis, using 45 rats, which were divided into 3 groups. In the Group 1, a defect was made at the proximal metaphysis of the tibia, inoculated by Staphylococcus aureus sensitive to Cephradine and Tobramycin and then filled with plaster of Paris pellet. In the Group 2, a defect was filled with Cephradine loaded plaster of Paris pellet. In the Group 3, a defect was filled with Tobramycin loaded plaster of Paris pellet. Then we observed the healing process of the bone defect in the point of view of the gross findings, radiologic findings and histologic findings at 4th, 8th and 12th week after operation. The results of this study were as follows:l. In the control Group;all 30 cases were infected. 2. In the Group 2;only 4 of 30 cases were infected. 3. In the Group 3;all 30 cases were not infected. 4. The plaster of Paris filled into the defect was absorbed continuously and stimulated the new bone formation.
Animals
;
Anti-Bacterial Agents
;
Calcium Sulfate
;
Cephradine
;
Debridement
;
Osteogenesis
;
Osteomyelitis
;
Rats
;
Staphylococcus aureus
;
Tibia
;
Tobramycin
4.Visual Motor Integration Abilities of Children with Learning Disorders.
Chang Jun COE ; Young Hyuk LEE ; Jung Keun KIM ; Ho Taek KIM ; Chang Ho HONG
Journal of the Korean Pediatric Society 1988;31(3):339-347
No abstract available.
Child*
;
Humans
;
Learning Disorders*
;
Learning*
5.Two Cases of Clear Cell Carcinoma of Ovary.
Chang Jin JEONG ; Ki Hong CHANG ; Yoon Ho LEE ; Jang Ho LEE
Korean Journal of Gynecologic Oncology and Colposcopy 1993;4(3):86-91
Clear cell carcinoma of ovary is a rare epithelial ovarian tumor, and increased in its incidence recently. Clear cell carcinoma of ovary was known t,o be highly malignant than other epithelial ovarian tumors. The clinical and pathologic findings of two casea af clear cell carcinoma of ovary are reported and reviewed briefly.
Female
;
Incidence
;
Ovary*
6.Clomerular deposition of fibrin(Ogen) in glomerulonephritis.
Dong Ho YANG ; Sae Yong HONG ; Chang Jin KIM
Korean Journal of Nephrology 1991;10(3):336-342
No abstract available.
Glomerulonephritis*
7.Shigelle, and Salmonella.
NamSu KIM ; Jae Ho LEE ; Chang Yee HONG
Journal of the Korean Pediatric Society 1982;25(11):1106-1119
No abstract available.
Salmonella*
8.Factors Influencing the Prognosis of Reye Syndrome.
Chang Ho HONG ; Heung Dong KIM ; Pyung Kil KIM
Journal of the Korean Pediatric Society 1987;30(11):1252-1258
No abstract available.
Prognosis*
;
Reye Syndrome*
9.An Immunohistochemical Stain in Paget's Disease.
Hong Tak LEE ; Seung Ho CHANG ; Tae Young YOON
Korean Journal of Dermatology 1998;36(5):796-803
BACKGROUND: Generally, there are few problems in the diagnosis of Paget's disease(PD) using the H&E stain. However, the differentiation of PD from the clonal type of Bowens disease and superficial spreading melanoma in situ that shows pagetoid spreading of tumor cells, may present diagnostic difficulties. In addition, the specia1 stains used for demonstrating the presenee of Pagets cells, such as PAS and mucicarmim, are non-specific and not always sensitive. So, inenunohistochemical stains with monoclonal antibodies against various antigens may be helpful for differentiating PD from ather morphologically similar skin lesions. OBJECTIVE: The purpose of this study was to investigate the diagnostic accuracy of immunohisto- chemical staining for diagnostic use in PD. METHODS: Immunohistochemical stains used in the biotin streptavidin amplificxl technique with monoclonal antibodies to several low rnolecular weight cytokeratin(CK)s, EMA and CEA, were performed on formalin-fixed, paraffin-embedded tissue. Twelve cases of PD(10 cases of extranmmmary PD and 2 cases of mammary PD), five cases of superficial spreading melanoma in situ and five cases of Bowens disease were investigated. RESULTS: The results were as follows. 1. Positive reactions with variable intensity using CK7, CKS, CK19 were seen in all cases(100%) of PD and the. staining intensity tor CK7 or CK19 was stronger than that of CKS. 2. Of the 12 cases of PD, both CK18 and CAM5.2 staining showed positivity in 11 cases(92%). 3. EMA and CEA staining showed positivity in 10(83%) and 9(75%) of 12 cases, respectively. 4. Some Pagets cells were negative for CK8, CK18 and EMA, although other positive cells were observed in the same sections. 5. All antigens were consistently negative in all cases of Bowens disease and superficial spreading melanoma in situ. CONCLUSION: The results show that moaoclonal antibodies to low molecular weight CKs are more sensitive than EMA or CEA in the demonstration of Pagets cells. Moreover, among the low molecular weight CK series, CK7 and CK19 are most useful for their high sensitivity and intensity.
Antibodies
;
Antibodies, Monoclonal
;
Biotin
;
Bowen's Disease
;
Coloring Agents
;
Diagnosis
;
Melanoma
;
Molecular Weight
;
Skin
;
Streptavidin
10.A Case of Infantile Myofibromatosis.
Hong Tak LEE ; Seung Ho CHANG ; Tae Young YOON
Korean Journal of Dermatology 1997;35(1):182-186
Infantile myofibromatosis is an uncornmon, benign, self-limiting, localized or generalized process, probably of hamartomatous origin, which consists to a large degree of cells having the characteristics of myofibroblasts and sometimes of pericytes. Both solitary and multicentric forms occur. Most lesions are present at birth or in early infancy, and some are familial in origin. A female newborn presented with a firm, round, red colored, 3 x 3 cm sized tumor with central necrosis on the left chest. Histological examination revealed well-circumscribed nodules consisting of short bundles of plump, spindle shaped cells displaying staining characteristics intermediate between fibroblasts and smooth muscle cells. The tumor was immunoreactive for actin but did not stain for desmin. A Follow-up examination at the age of 3 months revealed a moderate degree of spontaneous regressior of the lesion.
Actins
;
Desmin
;
Female
;
Fibroblasts
;
Follow-Up Studies
;
Humans
;
Infant, Newborn
;
Myocytes, Smooth Muscle
;
Myofibroblasts
;
Myofibromatosis*
;
Necrosis
;
Parturition
;
Pericytes
;
Thorax