1.A Study on the Relation of BMI to Lipid Metabolism and Health Promoting Behavior in Middle-Aged Women.
Kun Ja LEE ; Chun Ja CHANG ; Jae Hee YU
Journal of Korean Academy of Community Health Nursing 2005;16(4):488-497
PURPOSE: This study examined the relation of BMI to lipid metabolism and health promoting behavior in middle-aged women. METHODS: The subjects were 113 women between 40 to 60 years of age. The data was collected from April 2003 to July 2004. BMI was measured using body composition analyzer and lipid metabolism were measured using automatic biochemical analyzer. Health promoting behavior was collected using a structured questionnaire. The SPSSWIN(10.0 version) program was used to analyze the data and get the descriptive statistics and Pearson's correlation coefficients. RESULTS: BMI was negatively correlated with HDL-c and positively correlated with triglyceride, but there was no significance between BMI and total cholesterol. There was no significance of correlation between BMI and total health-promoting behavior. CONCLUSION: This study showed that BMI is meaningful in the identification of the high risk women to prevent HDL-c & triglyceride metabolism disturbance, but additional research is needed to study the correlation between BMI and health promoting behaviors in middle-aged women.
Body Composition
;
Cholesterol
;
Female
;
Humans
;
Lipid Metabolism*
;
Metabolism
;
Triglycerides
;
Surveys and Questionnaires
2.A Case of Atypical Fibroxanthoma.
Soo Il CHUN ; Hee Yong PARK ; Chang Jo KOH
Korean Journal of Dermatology 1984;22(4):454-458
We described a 65-year-old woman with a papule on the left temple area of } year duration. The lesion showed typical findings of atypical fibroxanthoma and was located on the lesion of solar keratosis, So sunlight may be the most important one among the various insults to atypical fibroxanthoma of the skin.
Aged
;
Female
;
Humans
;
Keratosis
;
Skin
;
Sunlight
3.A Case of Intracranial Malignant Teratoma.
Bong Kwon CHUN ; Hee Kyung CHANG ; Man Ha HUH
Korean Journal of Pathology 1990;24(1):85-90
The authors report a case of malignant teratoma in a 3-year-old girl who suffered from occipital headache and vomiting for about 2 months. The tumor occupied left cerebellopontine angle resulting in a moderate degree of hydorcephalus. Histologically, the tumor consisted mainly of neuroepithelial tissues showing varying degrees of differentiation, with areas of epidermis, mature fat tissue, connective tissue, gastrointestinal glands and smooth muscle bundles containing ganglions. Also noted are groups pf polygonal or spindle cells representing immature mesodermal tissue. In contrast to two malignant intracranial teratomas previously reported in Korean literatures, this case is characterized by the presence of predominent neuroepithelial components and by uncommon tumor location, the posterior fossa far from middle line of the body.
4.Restoration of Hormone Dependency in Estrogen Receptor - Lipofected MDA-MB-231 Human Breast Cancer Cells.
Young Jin SUH ; Jae Hee CHANG ; Chung Soo CHUN
Journal of the Korean Cancer Association 1999;31(3):473-482
PURPOSE: The loss of estrogen and progesterone receptors appeats to be associated with a progression to less differentiated and hormone-independent tumors. The gain of hormone independency over time even in estrogen receptor-positive tumors has become another obstacle to endocrine therapy for breast cancer. We tried to regain the hormone dependency in estrogen receptor-negative breast cancer cells by lipofecting estmgen receptor cDNA. MATERIALS AND METHODS: The mutant human estrogen receptor cDNA (pSGS-HEO) was lipofected into estrogen receptor-negative human breast cancer cell line MDA-MB-231, in an attempt to restore their sensitivity to antiestrogen. Then the effects of 17p-estradiol and tamoxifen were studied by counting viable cell numbers after treating the lipofected cell line with either one or together. RESULTS: Culture medium cantaining phenol red, a weak estrogen, has growth advantages compared with culture medium without it. In both culture conditions, cell growth was most profoundly inhibited in 4 days after lipofection with mutant human estrogen receptor cDNA, which was overcome after that day. Tamoxifen, as an antiestrogen, showed a growth inhibitory effect slightly stronger tban combined conditions of tamoxifen and 17- estradiol compared to estrogen-treated group and to control, and the inhibitory effect was lasted 4 days. CONCLUSION: The temporary induction of estrogen receptor by lipofection with pSGS-HEO on estrogen receptor-negative human breast cancer cell line MDA-MB-231 showed negative growth control on these cells by tamoxifen, indicating that liposome-mediated estrogen receptor transfection may be used as a novel therapeutic strategy for hormane independent human breast cancers in the near future.
Breast Neoplasms*
;
Breast*
;
Cell Count
;
Cell Line
;
DNA, Complementary
;
Estradiol
;
Estrogen Receptor Modulators
;
Estrogens*
;
Genetic Therapy
;
Humans*
;
Phenolsulfonphthalein
;
Receptors, Progesterone
;
Tamoxifen
;
Transfection
5.A radiologic findings of periappendiceal abscess : comparison of simple abdomen, B.E., and ultrasonography
Kyung Hee JUNG ; Jae Chun CHANG ; Mi Soo HWANG
Journal of the Korean Radiological Society 1985;21(6):975-984
With simple abdomen, double contrast colon study, and ultrasongraphy, authors retrospectively analyzedradilogic findings of 46 cases which were proved periappendiceal abscess, due to perforation of appendix, byhistology or follow-up ultrasnongraphy from May in 1983 to July in 1985 at Yeung-Nam University Hospital. Theresuls obtained were as follows: 1. Of 46 cases, 24 cases were males and 22 cases females, with the results ofabove statistics, periappendiceal abscess was not influenced by sex. 2. Periappendiceal abscess was mostfrequently demonstrated in forties. 3. Comparison of ultrasonography and B.E. Pseudorenal pattern(Ultrasonography)- well defined defect (B.E.) Cystic pattern(Ultrasonography)- serrated defect (B.E.) 4. Missed 2 cases inultrasonography were detected in B.E., i.e. sensitivity of B.E. is higher than that of ultrasonography. 5.Differences of ultrasonography and B.E.
Abdomen
;
Abscess
;
Appendix
;
Colon
;
Female
;
Follow-Up Studies
;
Humans
;
Male
;
Retrospective Studies
;
Sensitivity and Specificity
;
Ultrasonography
6.Sympathetic skin response in spinal cord injury patients.
Hee CHEONG ; Sei Il CHUN ; Chang Il PARK
Journal of the Korean Academy of Rehabilitation Medicine 1993;17(4):515-524
No abstract available.
Skin*
;
Spinal Cord Injuries*
;
Spinal Cord*
7.Two cases of Korean hemorrhagic fever complicated with pregnancy.
Sun Hee CHUN ; Mi Young CHANG ; Young Ju KIM ; Bok Hee WOO
Korean Journal of Obstetrics and Gynecology 1992;35(5):778-782
No abstract available.
Hemorrhagic Fever with Renal Syndrome*
;
Pregnancy*
8.MR Features in Lymphedema and Phlebedema of Extremities.
Chang Soo KIM ; Chun Phil CHUNG ; Jeong Hee YOON ; Tae Myung MOON
Journal of the Korean Radiological Society 1994;31(4):737-742
PURPOSE: Authors analyzed the MR findings of swollen extremities to evaluate the MR features of lymphedema and phlebedema. MATERIALS AND METHODS: We reviewed MR imagings of 17 cases of swollen extremities, including 12 lymphedemas and 5 phlebedemas. We obtained axial TI-, T2-, and Gd-DTPA enhanced T1WIs using 1.0T superconducting magnet and measured cross-sectional areas of subcutaneous and subfascial tissues of a slice with grossly largest cross-sectional area using perimeter. We also analyzed changes in the signal intensities of the subcutaneous and subfascial tissues on T2WI, presence of enhancement on Gd-DTPA enhanced T1WI, and presence of skin thickening. RESULTS: Both subcutaneous and subfascial tissues of swollen extremities were increased in the cross-sectional areas than those of contralateral normal side. The subcutaneous compartment in lymphedema was statistically significantly increased in cross-sectional area than subfascial compartment in lymphedema(p<0.005) and subcutaneous tissue in phlebedema(p<0.05). Increased signal intensities and characteristic "honeycomb appearance" of subcutaneous tissue in the lymphedema were specific findings on T2WI. CONCLUSION: MR imaging was useful and noninvasive method in the diagnosis of swollen extremities. There were increased cross-sectional area of subcutaneous compartment with "honeycomb appearance" in lymphedema and increased signal intensities of both subcutaneous and subfascial compartment in phlebedema on the T2WI.
Diagnosis
;
Extremities*
;
Gadolinium DTPA
;
Lymphedema*
;
Magnetic Resonance Imaging
;
Skin
;
Subcutaneous Tissue
9.A Study on the Relationship among Climacteric Symptoms, Knowledge of Menopause and Health Promoting Behavior in Middle-Aged Women.
Kun Ja LEE ; Chun Ja CHANG ; Jae Hee YOO
Korean Journal of Women Health Nursing 2003;9(4):400-409
PURPOSE: This study was to identify the correlations among climacteric symptoms, knowledge of menopause and health promoting behavior in middle-aged women. METHOD: 1,360 women between 40-60 years of age living in Incheon, were asked to complete a questionnaire on their health. The data was collected between October 10th and October 30th, 2002. The data was analyzed using T-test, ANOVA and Pearson's correlation coefficients with SPSS/pc program. RESULT: The variables significantly affecting climacteric symptoms, knowledge of menopause and health promoting behavior were education, perceived health status and family health problems. The relationship between knowledge of menopause and health promoting behavior was statistically significant with a positive correlation. CONCLUSION: The knowledge of menopause by middle aged women was in positively correlated with health promoting behavior. Therefore, based on this study, we plan to develop a health education program to promote knowledge of menopause and health promoting behavior.
Climacteric*
;
Education
;
Family Health
;
Female
;
Health Education
;
Humans
;
Incheon
;
Menopause*
;
Middle Aged
;
Surveys and Questionnaires
10.Keratosis Punctata Palmaris et Plantaris in a Patient with Hepatoma.
Min Geol LEE ; Kyung Hee WHANG ; Won Ho LEE ; Soo Il CHUN ; Chang Jo KOH
Korean Journal of Dermatology 1982;20(1):163-169
No abstract available.