Nursing care was given to 48 HBV-related liver failure cases with abdominal distension through the application of Qi-Tou-Xiao-Gu therapy. It was showed that key points in nursing care should contain aspects of
correct selection of cases, detailed explanation, observation during application, maintain the moisture of Qi-Tou-Xiao-Gu stick, emotional regulation, and cross infection prevention. Good nursing care can improve patients' com-fort degree and satisfaction to the treatment. It can also effectively relieve abdominal distention and reduce ad-verse reactions.

Objective To study the value of transthoracic echocardiography (TTE) in interventional treatment of congenital heart diseases. Methods TTE was used to identify patients with atrial septal defect (ASD, n=26), ventricular septal defect (VSD, n=23) or ductus arteriosus (PDA, n=16). They received interventional treatment with domestic made nitinol occluder. The TTE was then used to monitor the entire process of the surgery and to assess the effect of the surgery. Results The treatment with indigenous nitinol occluder failed in five patients, including two with ASD, two with VSD, and one with PDA. The other sixty-one patients were freated successfully with the occluder. Once the procedure was completed, those patients were found to have neither abnormal valvular regurgination as shown by TTE, nor any shunt flow around the occluder as shown by both TTE and angiocardiography. One month later, TTE demonstrated that the position of all the occluclers remained stable, and no residual leakage or shunt was detected by TTE in all of the sixty-one patients, and the same results were obtained after three months. However, two days after the surgery, ECG showed that three of the patients with VSD suffered from different degrees of atrioventricular block on the second postoperative day, but they eventually recovered after treatment. The successful rate of the procedure was 93.8% (61/65). Conclusions Transthoracic echocardiography may play an important role at three stages (pre-, during- and after), i.e. to select the most suitable patients before the procedure, accurately identify the location, and release of the occluder at the end of the operation; and finally, it serves as a promising method to evaluate the treatment result in patients during their follow-up period.

[Objective]We have made the entity model of human being injured irregular bone model by using rapid prototyping technogy,and discussed the value and prospect of rapid prototyping technology in clinical orthopedics.[Method]This group included 23 cases:15 cases of calcaneus fracture,4 cases of fracture of tibial plateau,2 cases of fracture of first lumbar vertebral body,1 case of scapula fracture,1 case of dysplasia and aseptic necrosis of femoral head.According to the data gotten from CT tomographic scan of 23 cases which had fracture of irregular bone,we made the entity model of bone injury using professional software and equipment,and put it into clinic practice to study the state of illness and tried to assist the operative treatment.[Result]Application of rapid prototyping technology helped to study the state of illness and assisted the operative treatment,and brang on a new mechanism of the trauma and operative methods.By using it we also shortened the operative time and reduced the hemorrhage in the operation,and improved the rate of success in the first operation in order to avoid the second operation.All these cases have received good treatment effects.[Conclusion]The rapid prototyping technology has broad prospect in clinical orthopedics.

Objective To investigate the therapeutic effects of curcumin(Cur)on trinitrobenzene sulphonic acid(TNBS)induced colitis and to investigate cytokines change in colon mucosa,spleen and sera.Methods Colitis was induced in SD rats by intrarectal injection of TNBS(100 mg/kg).Experi- mental animals were divided into negative control group,TNBS group and Cur therapeutic group(Cur, 30 mg?kg~(-1)?d~(-1),intraperitoneal injection).Expression of cytokines mRNA in colon mucosa was observed by RT-PCR,intracellular cytokines of interferon(IFN)-?and interleukin(IL)-4 in splenocytes were detected by flow cytometry(FCM),concentrations of IFN-?and IL-4 in sera were determined by enzyme-link immunosorbent analysis(ELISA).Results After treatment with Cur,macroscopic scores (3.9?1.0 vs.2.2?0.7),myeloperoxidase(MPO)activity(15.0?2.6 vs.7.3?1.4),mRNA of IFN-?(1.02?0.07 vs.0.06?0.02,mRNAof IL-12(0.29?0.05 vs.0.11?0.01)and the ratio of IFN-?/IL-4(11.44?0.97 vs.0.38?0.10)in colon mucosa,proportion of IFN-?CD4~+(31.7?7.5 vs. 21.1?3.7)and the ratio of IFN-?/IL-4 CD4~+(19.9?5.1 vs.6.1?1.8)in splenocytes,concentra tions of IFN-?[(1528?159)pg/ml vs.(513?14)pg/ml] and the ratio of IFN-?/IL-4(19.5?4.1 vs. 4.2?0.6)in sera were all decreased(P＜0.05 or P＜0.01).Meanwhile,mRNA of IL-4(0.09?0.01 vs.0.15?0.04)and IL-10(0.28?0.08 vs.0.63?0.12)in colon mucosa,proportion of IL-4 CD4~+ (1.6?0.5 vs.3.4?1.1)in splenocytes and concentrations of IL-4 in sera[(81?15)pg/ml vs.(124?20) pg/ml] were all increased after the treatment of Cur(P＜0.05 or P＜0.01).Conclusions Cur showed ther- apeutic effects on TNBS-induced colitis,and the mechanism might be through regulating the balance of Th1/ Th2 in colon locally and systematically.

Objective To abserve the acute toxicity in mice administered with Wuweizi Ningshen oral liquid.Methods The maximum administration dosage(MAD)of Wuweizi Ningshen oral liquid were determined by administration intragastricly in mice.Wuweizi Ningshen oral liquid was administered for 2 weeks,and the growth condition,body weight growth and index of main viscera were measured.Results The index of growth condition,body weight growth and index of main viscera were in normal ranges.Conclusion It could be concluded that Wuweizi Ningshen oral liquid is safe to be administered in the dose prescribed.

This study was aimed to discuss possible problems in the data collection process of traditional Chinese medicine (TCM) clinical medicine and to propose appropriate solutions. Based on analysis of clinical data features and data collection demands among 20 TCM clinical research bases, reference were made on key technologies of the Electronic Medical Records' integration and sharing, to propose the solution of TCM clinical data collection. The re-sults showed that proposing the metadata and data entities synchronized intersecting strategy, analyzing key points on this strategy, and proposing appropriate solutions, found the technical processes of the TCM clinical data collec-tion. It was concluded that the analysis and solution on key points of TCM clinical data collection provided the basis and the reference to data collection issues of TCM clinical research base.

Objective To study the correlation between isokinetic parameters and modified Ashworth Scale (MAS) in ankle spasticity as-sessment. Methods 18 stroke patients (spasticity group) and 16 healthy subjects (control group) in our hospitals from August 2014 to March 2015 were included. MAS was used to assess the ankle muscular tension. The ankle passive movement of both groups was measured with BIODEX isokinetic motor assessment system under 10 °/s, 60 °/s, 120 °/s, 180 °/s, 240 °/s. The peak torque (PT), peak torque/body weight (PT/BW), average torque (AT), and slopes of the linear regression curve of torque-velocity (SLOPE) were recorded. The correlation of the isokinetic paramenters and the MAS were tested with Spearman correlation analysis. Results The PT, PT/BW and AT were higher in the spasticity group than in the control group (P<0.05). And they increased as the angular velocity increased, and slowed after 120 °/s. The corre-lation coefficient of MAS and PT, PT/BW, AT, SLOPE were from 0.3043 to 0.7632 (P<0.01). Conclusion The isokinetic parameters were speed-dependent and closely related to MAS. 120 °/s was of the highest sensitivity, and the SLOPE under this anglular velocity was highly correlated with MAS.

Objective To compare the accuracy of output factor calculation for rectangular inserts of electron beams by using three kinds of algorisms: square root, one dimensional formula and area periphery ration. Methods The differences between the values of output factor calculated by these three algorithms mentioned above and the results measured by ionization chamber for seven rectangular inserts were compared. Results When beam energy was fixed, the difference between calculated and measured output factors was larger for area periphery ration algorithm than that of the square root or one dimensional formula algorithms. The electron cone size, beam energy and rectangular inserts size all had some effect on the value of output factor calculated by the three algorithms. Conclusions The area periphery ration algorithm is not recommended for clinical use because of its great deviation. One dimensional formula and square root algorisms possess a good accuracy. One dimensional formula is superior to square root algorithm, but square root algorithm is more practical for clinical use.

Objective: To explore the relation of psychological abuse and neglect in childhood and college students’ mental health. Methods: Cluster sampling was used to select 457 college students studying in the Central South University and Hunan Commercial College as subjects. The general information questionnaire,Child Psychological Abuse and Neglect Scale (CPANS) and Symptom Checklist 90 (SCL-90) were completed by all subjects. Results: 45.30% of the respondents experienced psychological abuse or neglect in childhood. The total score and scores of each factor of SCL-90 of the group of psychological abuse combined with neglect was above those of psychological-abuse group,neglect-group and neither-abuse-nor-neglect-group. Additionally,ten factor scores and total score of SCL-90 of neglect-group were distinctly higher than those of neither-abuse-nor-neglect-group. The scores of each aspect and sub-scale of CPANS were significantly correlated with every factor and total score of SCL-90(P

Objective To explore the curative mechanism of Jieyuan (JY) Capsule on rats renal failure induced by 5/ 6 nephrectomy. Methods Chronic renal failure (CRF) rat models induced by 5/6 nephrectomy were administered with JY Capsule. The serum levels of blood urea nitrogen (BUN) and serum creatinine (Scr),hematological and biochemical indexes,and renal histological features were observed. Results JY Capsule reduced levels of BUN and Scr,ameliorated the electrolyte,increased the number of red blood cell and hemoglobin content,and alleviated pathological changes of the kidney tissue. Conclusion JY Capsule can relieve the rat CRF symptoms and postpone the progress of CRF.