1.Prevention and treatment of post-prostatectomy incontinence
China Oncology 2014;(3):231-234
Postoperative incontinence is one of the most feared complications of radical prostatectomy with a major impact on patients’ quality of life. There are several ways to treat with the incontinence including pelvic lfoor muscle training and medication as the conservative treatment, nerve-sparing approach during the operation and the urethral sling and the artificial urinary sphincter placement as the operative treatment. The aim of this article is to evaluate the treatment stated above to provide some guidance to deal with post-prostatectomy incontinence.
2.Preparation of Carboxybetaine-based Hydrophilic Interaction Chromatographic Column and Its Performance Exploration
Yuyang CHANG ; Xiaojun DAI ; Bolin GONG
Chinese Journal of Analytical Chemistry 2017;45(5):734-740
2-(Dimethylamino)ethyl methacrylate and sodium monochloroacetate were employed to synthesize [2-(Methacryloyloxy)ethyl] dimethyl ammonium acetate (CBMA) functional monomer.CBMA was grafted on the surface of silica by surface initiated atom transfer radical polymerization (SI-ATRP) to obtain silica-CBMA hydrophilic interaction stationary phase.Three silica-CBMA stationary phases with different grafted density of CBMA monomer were synthesized in SI-ATRP progress by changing the concentration of CBMA under the same conditions.The ability to separate organic acid compounds of the synthesized silica-CBMA stationary phases was evaluated under different conditions, including effects of pH value, salt concentration and content of water of mobile phase on retention of solutes.The results showed that the stationary phases could effectively separate organic acid compounds in HILIC mode, which followed a mixed mode of chromatography of ion exchange and hydrophilic interaction.The retention of solutes decreased with the increases of salt concentration of mobile phase, which consistent with the characteristics of ion exchange;the pH value of mobile phase had significant influence on ionization of the stationary phase and solutes, i.e., the retention of solutes increased as the increasing of pH value of mobile phase.However, the retention of solutes decreased with the increasing of the content of water in mobile phase, which was the typical characteristic of HILIC.The method of hydrophilic interaction chromatography combined with silica-CBMA stationary phases could conveniently determinate the content of vitamin C and rutin in rutin tablets, providing a new method for the separation and determination of strong polar samples.
3.Statistical Observation of Hematuria with Urologic Diseases.
Soe Young LEE ; Woo Won CHANG ; Dai Soo CHANG
Korean Journal of Urology 1968;9(4):189-193
Pyuria, pain and hematuria are the predominant symptoms in urologic diseases. Among them hematuria is the most important complaint referable to the urinary tract in both children and adults Accordingly, hematuria should never be ignored, and no matter how trivial the bleeding a complete urologic investigation into itscause is mandatory. A statistical survey was made on hematuria of the in-patientsin the Department of Urology at ST. Mary's Hospital, during the two years from August 1966 to July 1968 and the following results were obtained. 1. During that period. out of 437 cases who were hospitalized, 246 cases(179 males and 67 females) had hematuria, giving a rate of 5t percent (gross: 24 percent, micro-hematuria: 30 percent) 2. More than 70 percent of all the cases of hematuria processed were found to be calculus, tumor and tuberculosis of the genitourinary tract. 3. Most frequent incidences of hematuria 'were shown to be trauma in children, while calculus, tuberculosis and tumor in young and middle aged group, and tumor in old aged group as well. 4. Among 141 cases of micro-hematuria, grade I showed 78 cases(55 percent) 5. The location of bleeding in 1O5 cases of gross hematuria was in the kidney by 40 percent, bladder, ureter and urethra in that order of frequency.
Adult
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Calculi
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Child
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Hematuria*
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Hemorrhage
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Humans
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Incidence
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Kidney
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Male
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Middle Aged
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Pyuria
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Tuberculosis
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Ureter
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Urethra
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Urinary Bladder
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Urinary Tract
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Urolithiasis
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Urologic Diseases*
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Urology
4.Reappraisal of Delorme's procedure for rectal prolapse.
Sung Yong YOON ; Joong Kil CHANG ; Seong Dai PARK
Journal of the Korean Surgical Society 1993;44(6):875-880
No abstract available.
Rectal Prolapse*
5.A Clinical Observation on Urethroplasty in 49 Cases with Urethral Injury.
Korean Journal of Urology 1971;12(4):393-399
A clinical observation on urethroplasty in 49 cases with urethral injury among 1150 patients which were admitted for urologic operation at department of urology, St. Mary's Hospital, C.M.C. during the period from Jan. 1966 through Aug. 1971 were performed. Of 49 cases, 37 cases were urethral rupture and remainder, urethral stricture. The urethral rupture was repaired by suprapubic urethroplasty and urethral stricture, by perineal urethroplasty (end to end anastomosis). The results were summarized as follows: 1. The rate of GU injury accounted for 9. 14% to the total operated inpatient and the rate of urethral injury for 46.7% to the G-U injury during 5 years and 8 months 2. The incidence of the urethral injury was the highest in the age of 21 to 30, and majority of the urethral injury (67.3%) was lied between the age of 21 and 50. 3. The most common cause of the urethral injury was car accident (57.1%) and others, recorded in the order of straddle injury and kick and blow. 4. Among 37 cases of urethral rupture, pubic bone fracture was associated in 19cases (51.4%). 5. Removal of urethral catheter after urethroplasty were 2~3 weeks in cases of urethral rupture and 1~2 weeks in the cases of urethral stricture. 6. 12 cases (100%) with urethral stricture were treated by perineal urethroplasty (end to end anastomosis).
Humans
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Incidence
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Inpatients
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Pubic Bone
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Rupture
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Urethral Stricture
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Urinary Catheters
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Urology
6.Clinical study on early colorectal cancer.
Shang Kyun RHO ; Jung Kil CHANG ; Seong Dai PARK
Journal of the Korean Surgical Society 1991;41(6):765-775
No abstract available.
Colorectal Neoplasms*
7.A Clinical Observation on the Normal and Movable Kidney of Korean.
Korean Journal of Urology 1971;12(3):277-286
The clinical and intravenous pyelographic studies on 513 cases of Korean with normal or movable kidneys at St. Mary's Hospital, Catholic Medical College, during the period from January 1965 through September 1969 were performed Of 513 cases, 215 cases, normal kidneys and others, movable kidneys. The results were summarized as follows; 1. The center of the right renal pelvis in the supine position was at the level of the upper part of the second lumbar vertebra, and that of the left was located at the L1-L2 level in normal kidney 2. The angle between the long axis of normal kidney and the vertebral column was 6 degrees - 20 degrees, and no differences were noticed between the right and left side. 3. The range of the angular change obtained by the postural change from the supine to the erect was 1'-10' in normal kidney. 4. The ratio of the movable kidney of the male and female was 1:1.6, and that of the right and left was 20:1. The incidence of the movable kidney was the highest in the age of 31 to 40, and majority of the movable kidney (80.5%) was lied between the age of 20 and 50. 5. The most common clinical findings of the movable kidney wag flank pain (40.6%) and other findings were recorded in the order of hematuria, frequency of urination, palpable mass on the renal region, pyuria and indigestion. 6. Among 52 cases of microscopic hematuria, grade 1 showed 30 cases (57.7%). 7. 104 cases (35.0%) of the movable kidney showed no subjective symptoms. 8. 139 cases (46.6%) of the movable kidney showed poor drainage of contrast media during I.V.P. taken in erect position. 9. Only 25 cases (8.3%) of the movable kidney were treated by operation.
Axis, Cervical Vertebra
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Contrast Media
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Drainage
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Dyspepsia
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Female
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Flank Pain
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Hematuria
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Humans
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Incidence
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Kidney Pelvis
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Kidney*
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Male
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Pyuria
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Spine
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Supine Position
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Urination
8.Automatic measurement of range of motion of human lower limbs using Kinect technique
Xiaolong ZHU ; Junze WANG ; Chang QU ; Aibo DAI
Chinese Journal of Physical Medicine and Rehabilitation 2014;36(10):778-783
Objective In order to improve the accuracy and efficiency of the measurement of range of motion (ROM) of human lower limbs and simplify process of ROM measurement,an automatic measurement of ROM of human lower limbs based on Kinect technique was proposed and tested in this study.Methods Fifty examinee were randomly divided into 5 groups,namely groups a,b,c,d and e,respectively,each group had 10 members.Using the human skeleton tracking technology from Kinect,the positions of the examinee's lower limbs were captured and tracked by processing the depth data of lower limbs' key joints.Then the information of ROM of hip and knee was output on human-computer interaction interface in real-time.By comparison with traditional manual measurement results,the accuracy of automatic measuring method could be verified.Meanwhile,with the aid of speech recognition and output technology,the mode of warning information transfer and the way of subject switch were optimized.Results According to the method of Grubbs-test and t-test,the ROM values | t | from the subjects' hip abduction (t =0.57,P =0.597),hip adduction (t =0.52,P =0.621),hip anteflexion (t =1.01,P =0.371),hip postextension (t =0.12,P =0.902),hip external rotation (t =0.00,P =1.000),hip internal rotation (t =0.34,P =0.753),knee flexion and extension (t =1.12,P =0.280) all were under the threshold value t0.025 (4) =2.776 on the premise of a level of significance α =0.05,which indicated that there was no significant difference between measured results and expected values(P > 0.05).Conclusion The automatic measurement of ROM of lower limbs can be realized which can improve the measurement accuracy,simplify the measurement process and enhance the practicability of ROM of lower limbs measurement.
9.Effects of heterogenous suberect spatholobus stem on peripheral blood cell counts of 60Co gamma ray irradiated mice
Hong WANG ; Ping LIU ; Chang DAI ; Dongxiao WANG
Journal of Integrative Medicine 2007;5(2):189-92
OBJECTIVE: To investigate the effects of heterogenous suberect spatholobus stem (Spatholobus suberectu, Mucuna birdwoodiana, Millettia oosperma and Millettia dielsiana) on peripheral blood cell counts of mice with bone marrow suppression induced by (60)Co gamma ray irradiation. METHODS: Bone marrow suppression was induced by sublethal dose of (60)Co gamma ray in mice. White blood cell (WBC), red blood cell (RBC) and platelet (PLT) counts in peripheral blood of the mice were detected one day, 3, 7, 14 and 21 days after intragastric administration of different doses of the four kinds of suberect spatholobus stem, respectively. RESULTS: A slowdown of the decrease of WBC, RBC and PLT counts in peripheral blood of the mice with bone marrow suppression was observed after intragastric administration. The WBC, RBC and PLT counts in the Mucuna birdwoodiana-treated and Spatholobus suberectu-treated groups were significantly higher than those in the untreated group (P<0.05). CONCLUSION: All the four kinds of heterogenous suberect spatholobus stem can accelerate the recovery of WBC, RBC and PLT counts in peripheral blood of mice with bone marrow suppression, while the effects of Spatholobus suberectu and Mucuna birdwoodiana are relatively good.
10.Relationship between the Change of IGF 1 and TGF-β1 Level and Renal Damage in Children with Allergic Purpura
Xin CHANG ; Zhibin DAI ; Guixian LI ; Lifang WANG
Journal of Modern Laboratory Medicine 2017;32(3):101-104,108
Objective To investigate the effects of insulin-like growth factor 1 (IGF 1) and transforming growth factor beta 1 (TGF-β1) in he pathogenesis of children with allergic purpura kidney damage.Methods 135 henoch-schonlein purpura (HSP) children with kidney damage were divided into HSP and HSPN group according to whether associated with renal damage,blood IGF 1,TGF-β1,urinary inhibition C (Cys C),creatinine (SCr) and content of urea nitrogen (BUN) were compared,and blood IGF-1,TGF-β1 and Cys C content of HSPN patients in different pathological grading were compared,the correlation of blood IGF 1,TGF-β1 and Cys C content of the HSPN group were analyzed,Results Blood IGF 1,TGF-β1 and Cys C content of the control group(117.2±18.8 ng/L,164.2±18.4 ng/L,0.9±0.2 mg/L),the HSP group(131.7±19.6 ng/L,282.1±28.3 ng/L,1.1±0.2 mg/L) and the HSPN group (205.3±24.5 ng/L,489.2±32.7 ng/L,1.3±0.3 mg/L) showed a trend of increasing gradually (F=4.824~45.066,P value<0.01),the HSP group and the HSPN group were higher than that of the control group (q=3.397~58.931,P value<0.01),the HSPN group was higher than that of the HSP group (q=16.997,35.193,P value<0.01),the difference was statistically significant.Blood IGF-1 (level Ⅱ 175.6 ± 20.4 ng/L,level m198.5±23.3 ng/L,level Ⅳ241.7±25.1 ng/L),TGF-β1(level Ⅱ 392.8±38.9 ng/L,level Ⅲ 481.3± 44.03 ng/L,level Ⅳ 537.6±42.9 ng/L),Cys C (level 11 1.1±0.3 mg/L,level Ⅲ 1.3±0.4 mg/L,level Ⅳ1.6±0.4 mg/L) content of children with HSPN increased with the increase of renal pathology classification (F=6.594~ 28.317,P value <0.01),blood IGF-1,TGF-β1 and Cys C content of kidney pathology classification of Ⅵ level in children was higher than that of the level of Ⅱ and Ⅲ in children (q=2.415~11.818,P<0.05 or P<0.01),while the contern of blood IGF-1,TGF-β1 and Cys C of level Ⅲ in children was higher than that of the level Ⅱ in children (q=2.577~6.244,P<0.05 orP< 0.01),the difference was statistically significant.Blood IGF-1,TGF-β1 content of children with HSPN were positively correlated with Cys C content of children (r=0.648,0.719,P<0.05),but blood IGF 1 content was significantly positive correlated with TGF-β1 content (r=0.748,P<0.05).Conclusion IGF 1 and TGF-β31 partieipated in the pathogenesis of HSPN,and both were correlated with the degree of the pathological damage.