1.Effect of cornary-caval shunt accompanied by pericardial devascularization in the treatment of upper gastrointestinal bleeding caused by portal hypertension
Jigang BAI ; Shunbin DONG ; Chang LIU
Chinese Journal of Hepatobiliary Surgery 2013;(1):8-10
Objective To investigate the short-term and long-term effect of cornary-caval shunt accompanied by pericardial devascularization in the treatment of upper gastrointestinal bleeding caused by portal hypertension.Methods Eleven patients with portal hypertension underwent cornary-caval shunt accompanied by partial pericardial devascularization were chosen.Of the 11 patients 6 applied autogenous splenic veins for graft and in 5 cases the coronary vein and inferior vena cava were anastomosed directly.Results Of the 11 patients,no operative mortality or early rebleeding.All patients were followed up from 5 months to 11 years with an average of 5 years and 3 months,of whom two died,others having no rebleeding or hepatic encephalopathy.Conclusion Cornary-caval shunt is a highly selective portosystemic shunt.Cornary-caval shunt accompanied by pericardial devascularization is a surgical treatment of upper gastrointestinal bleeding caused by portal hypertension for its apparent regional antihypertensive effect,the normal blood flow of liver,and reduction of the incidence of rebleeding.
2.Biological ingredient analysis of traditional Chinese medicines utilizing metagenomic approach based on high-throughput-sequencing and big-data-mining.
Hong BAI ; Kang NING ; Chang-yun WANG
Acta Pharmaceutica Sinica 2015;50(3):272-277
The quality of traditional Chinese medicines (TCMs) has been mainly evaluated based on chemical ingredients, yet recently more attentions have been paid on biological ingredients, especially for pill-based preparations. It is a key approach to establish a fast, accurate and systematic method of biological ingredient analysis for realization of modernization, industrialization and internationalization of TCMs. The biological ingredient analysis of TCM preparations could be abstracted as the identification of multiple species from a biological mixture. The metagenomic approach based on high-throughput-sequencing (HTS) and big-data-mining has been considered as one of the most effective methods for multiple species analysis of a biological mixture, which would also be helpful for the analysis of biological ingredients in TCMs. Simultaneous identification of diverse species, including the prescribed species, adulterants, toxic species, protected species and even the biological impurities introduced through production process, could be achieved by selecting appropriate DNA biomarkers, as well as applying large-scale sequence comparison and data mining. By this approach, it is prospective to offer an evaluation basis for the effectiveness, safety and legality of TCM preparations.
Biological Products
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chemistry
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Data Mining
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High-Throughput Nucleotide Sequencing
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Medicine, Chinese Traditional
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Metagenomics
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methods
3.Development of the independent dose verification for treatment planning system in radiotherapy
Sheng CHANG ; Guangjun LI ; Sen BAI
Chinese Journal of Radiological Medicine and Protection 2016;36(10):790-796
With the rapid development of intensity modulated radiation therapy (IMRT) technique,the accuracy of radiotherapy has improved,while the pretreatment dose verification has become more complex.Although the experimental measurements,a widely used way to perform dose verification,is accurate and effective,its time-consuming and labor-intensive is still a challenge for physicist.The independent dose verification method such as the depth dose-off axis ratios (OAR) empirical model,Clarkson integral model,convolution model and Monte Carlo model,could partially solve these problems effectively when the accuracy is ensured within a certain range.This approach could save physicists' time to conduct dose recalculation and plan check,and has become the hotspot in the world.This paper,therefore,mainly introduces the correction-based and the model-based independent dose verification methods,and briefly discusses the development of dose verification for IMRT plans.
4.Preparation and Clinical Application of Sophora Alopecurodies Suppository
Di REN ; Wei CHANG ; Jinliang BAI
China Pharmacy 2001;0(08):-
OBJECTIVE:To prepare Sophora alopecurodies suppository for treating prostatitis chronica and observe its clinical therapeutic effect METHODS:The content of the total alkaloid in the suppository was determined with acid dye spectrophotometry and the therapeutic effect was observed in comparison with qianliean suppository RESULTS:The linear range of TASa was 0 14~15 4?g/ml,standard oxymatriner's recovery was 101 2%,RSD=0 55% CONCLUSION:This suppository is simple in preparation,reliable in quality-control It is slight in irritation to rectum and effective in clinical use The preparation is worth popularizing in clinical practice
5.Clinical Observation of the Acute Osteomyelitis in Children
The Journal of the Korean Orthopaedic Association 1978;13(3):353-957
The clincal experience of thirteen patients with proven acute osteomyelitis under twelve years of age treated by surgical exprolation such as immediate decompression followed by continuous suction-irrigation. Five patients of them who had short duration from the onset improved while three patients who had long duration from the onset had persisting inflammatory change of the bone in spite of the regimen. The causating organisms were mostly staphylococcus aureus in bacterial cultures. The combination of gentamycin, minocin and penclox were the antibiotics of choice. Early diagnosis and early operation is advocated to attain good results in the treatment of acute osteomyelitis in the children.
Anti-Bacterial Agents
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Child
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Decompression
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Early Diagnosis
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Gentamicins
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Humans
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Minocycline
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Osteomyelitis
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Staphylococcus aureus
6.Role of polycyclic aromatic hydrocarbons and aryl hydrocarbon receptor in the development of tumor
Yuxia HU ; Fuhou CHANG ; Tuya BAI ; Xiaoli LV ; Wanjia YU
Chinese Journal of Biochemical Pharmaceutics 2015;(6):185-188
Polycyclic aromatic hydrocarbons ( PAHs) are ubiquitous environmental pollutants, whose carcinogenicity is determinated.The mechanism of their carcinogenicity: PAHs are able to combine with aryl hydrocarbon hydrocarbon receptor ( AhR ) , resulting in some toxicity and carcinogenicity.AhR is a ligand-dependent activation transcription factor, which is activated by a large variety of ligands, regulating the expression of a series of gene involved in metabolism, and participating in important biological processes, such as singal transduction, cell proliferation,differentiation and apoptosis,and so on.Besides, it's closely related with the tumor development.Thus, it will provide a new approach for cancer prevention and treatment to study the role of PAHs and AhR in the development of tumor.
7.Application of Two Kinds of Video Laryngoscope in General Anesthesia during UPPP Operation
Guiping WANG ; Lihua CHANG ; Peng ZHANG ; Jiujian WANG ; Guang BAI
Tianjin Medical Journal 2014;(8):822-824
Objective To compare success rate of intubation and safety of two types of video laryngoscopes during anesthesia in uvulopalatopharyngoplasty surgery (UPPP) for obstructive sleep apnea syndrome (OSAS) patients. Methods UPPP surgery were operated to 60 patients between January and October of 2013 and those patients were randomly divided into McGrath MAC video laryngoscope group (M group), GlideScope video laryngoscope (G group), and SHUCMAN direct la-ryngoscopy (S group), with 20 patients per group. Mallampati classification scores, Cormack-Lehane grade, intubation suc-cess rate, pre-intubation vs post-intubation heart rate and blood pressure changes were recorded and compared. Results Mallampati classification scores were not significantly different between these three groups, and Cormack-Lehane grade be-tween M group and G group were also not statistically different. M and G group had distinct advantages in Cormack-Lehane grade, success rate in intubation, heart rate, blood pressure at completion of intubation (T3) and 1 minute after intubation (T4), and the differences are statistically significant (P < 0.05). Blood pressure changes were stabler in G group than M group. Conclusion The two video laryngoscopes used in anesthesia intubation during UPPP surgery can both effectively re-veal the structure of the throat, but also work with high success rate and safety. What’s more, in this study the McGrath MAC video laryngoscope was shown to be superior to GlideScope video laryngoscope.
8.Three successful cases treated with moxibustion and embedding needle at auricular points.
Yong-Qing LIN ; Ming chang ZHENG ; Bai-Xiao ZHAO
Chinese Acupuncture & Moxibustion 2013;33(6):571-572
Acupuncture Points
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Acupuncture, Ear
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Adult
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Dizziness
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therapy
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Headache
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therapy
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Humans
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Male
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Middle Aged
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Moxibustion
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Rhinitis, Allergic, Seasonal
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therapy
10.Re-repture after primary flexor tendon repair of the hand.
Dong Bai SHIN ; Bum Soo KIM ; Chang Sung SO
The Journal of the Korean Orthopaedic Association 1997;32(3):719-724
In the treatment of flexor tendon injury of the hand, re-rupture after primary tendon repair is one of complications which occurs occasionally and so impose burden on both the patient and the surgeon. Authors experienced twelve cases of re-rupture after primary flexor tendon repair of 274 patients from Mar. 1989 to Mar.1996. The incidence of re-rupture after primary flexor tendon repair was 4.4% in author's series. One case happened with slip down injury, and in six cases re-rupture occurred during physical therapy with snapping click sound. However in five cases, the patients conldnt recognize any related causes. In majority of cases, re-ruptures were identified between three and five weeks after primary repair by the surgeon and the patient, so it could be suggested that the attention should be paid for the high possiblity of re-rupture during this period. Operative findings were the resorption and friability of repaired end with insecure suture fixation in two cases, rupture of suture material in four cases and loosening of the knot in six cases. From this study, the authors suggest the importance of knot, and recommend to make more than four knots on suture tie with attention to the tie direction, and advise careful physical therapy according to each patients' different situation. In the treatment of re-rupture, end-to-end re-anastomosis was available in seven cases (59%). In five cases (41%), tendon graft was needed. The clinical result of the re-rupture cases was evaluated by the Stickland evaluation method, and it was satisfactory in 67% of the patients who had the complication of re-rupture.
Hand*
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Humans
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Incidence
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Rupture
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Sutures
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Tendon Injuries
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Tendons*
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Transplants