Protermycin, the first molecular synthetic of tetracycline and chloramphenicol, has been given trial in 28 patients: acute gonococcal urethritis 10, nongonococcal urethritis 7, acute cystitis 6, chancroid 1 and postoperative cases 4. The doses ranged from 300 to 600 me daily. From this study, it was found that Protermycin proved itself to be most effective in nongonococcal urethritis which could not be treated satisfactorily by other antibiotics. Of 28 cases, 25 showed good result. The remaining 3 cases failed to respond.
Anti-Bacterial Agents ; Chancroid ; Chloramphenicol ; Cystitis ; Humans ; Tetracycline ; Urethritis

A clinical survey on the condyloma acuminatum in the army was carried out during the period of 16 months from July, 1976 to Dec., 1977 by means of ready-made chart and questionare. This study concems a series of 100 maIe patients treated in the ROK Army Hospital. The result can be summarized as follows: 1. 91% of the patients were between the age of 21 and 25, the commonest age being 24(31%) years. The average age was 23.6 years. 86%. of the patients experienced their first sexual contact between the age of 18 and 22, the commonest age being 20 (22%) and 2l(22%) years. The average age was 20years. 2. Predilection sites of the condyloma acuminatum were coronal sulcus (32%), perianal region(22%), glans penis(7%), urethral meatus(7%) and prepuce(4%) 3. Barmaid (58%) was the most frequently suspected sources of prsent infectian and other suspected sources were the prostitute (15%) and the lover (7%). 4. Among the 100 cases of condyloma acuminatum, 78 cases (78%) faund. their skin lesion 1 to 6 months after sexual contact and 49 cases (49%) found it within 8 months. Average incubation period was 3. 7 months. 5. Thirty two cases (32%) of condyloma acuminatum had a past history of other STD and 18 casea (18%) had other coincidently combined STD which were composed of syphilis (15%), urethritis (2%) and chancroid (1% ).
Chancroid ; Hospitals, Military ; Humans ; Sex Workers ; Skin ; Syphilis ; Urethritis

Chancroid is an acute localized, autoinoculable venereaI disease caused by Haemophilus ducreyi, characterized clinicaIly by painful ulceration at the site of incubation, and frequently accompanied by regional lymphadenopathy, and short incubation period. Three cases of chancroid were seen in Won Ju city, Kangwondo, Korea. All of the patients were male, and painful ulcers developed on genital region in 2 to 3 days after sexual contacts. Direct smear showed the characteristic "school-of-fish" arrangement of Haemophilus ducreyi by Gram stain. There were no regional lymphadenopathies and VDRL test were negative. Treatments were done with sulfisoxazole (Gantrisin) in case I, with sulfamethoxydiazine(Bayrena) and streptomycin in case 2, and with sulfamethoxydiazine and tetracycline in case 3 with exccllent results.
Chancroid* ; Gangwon-do ; Haemophilus ducreyi ; Humans ; Korea ; Lymphatic Diseases ; Male ; Streptomycin ; Sulfameter ; Sulfisoxazole ; Tetracycline ; Ulcer

Sexually transmitted diseases (STDs) are the most common infectious diseases worldwide, with over 350 million new cases occurring each year, and have far-reaching health, social, and economic consequences. Failure to diagnose and treat STDs at an early stage may result in serious complications and sequelae. STDs are passed from person to person primarily by sexual contact and are classified into varied groups. Some cause mild, acute symptoms and some are life-threatening. They are caused by many different infectious organisms and are treated in different ways. Syphilis and gonorrhea are ancient afflictions. Now, however, Chlamydia is prevalent and has become the most common bacterial STD. Antimicrobial resistance of several sexually transmitted pathogens is increasing, rendering some regimens ineffective, adding to therapeutic problems. A standardized treatment protocol for STDs is recommended to ensure that all patients receive adequate treatment. Appropriate treatment of STDs is an important public health measure.
Chancroid ; Chlamydia ; Clinical Protocols ; Communicable Diseases ; Dietary Sucrose ; Gonorrhea ; Humans ; Public Health ; Sexually Transmitted Diseases ; Sexually Transmitted Diseases, Bacterial ; Syphilis

Nonsexually acquired genital ulceration (NSAGU) is characterized by the abrupt appearance of painful genital ulcers, most often in young women. The onset may be preceded by an acute systemic illness such as fever or malaise, and many of the patients have a history of oral aphthosis. Its pathogenesis is not fully understood. In our case, a 72-year-old male visited with multiple painful erythematous ulcers on the perianal area. By history taking, laboratory tests, and skin biopsy, we excluded etiologies such as herpes simplex virus infection, syphilis, chancroid, and Behcet's disease. Thus, we diagnosed the patient with NSAGU and treated him with systemic steroids, nonsteroidal anti-inflammatory drugs, antibiotics, cyclosporine, and triamcinolone injection. Approximately 13 months after resolution, there had been no relapse. NSAGU is an uncommon condition and underrecognized by physicians. There have been no documentarily reported cases of NSAGU in Korea. Therefore, we present a case of NSAGU on the perianal area in an elderly man.
Aged* ; Anti-Bacterial Agents ; Biopsy ; Chancroid ; Cyclosporine ; Female ; Fever ; Humans ; Korea ; Male ; Recurrence ; Simplexvirus ; Skin ; Steroids ; Syphilis ; Triamcinolone ; Ulcer*

BACKGROUND: In the management of patients with sexually transmitted diseases(STD), contact tracing is fundamental to get the information of sexual partners to be responsible of STD transmission. OBJECTIVE: The aim of this study was to obtain statistical data of the sexual partners for more effective STD control. METHOD: In order to obtain statistical knowledge of the sexual partners, we retrospectively reviewed medical records of 11,333 male patients who visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul from January 1986 to December 1995. RESULTS: As the source of STD transmission for 11,333 male patients, the so called 'high risk groups' comprised 77.6% including prostitutes 38.3%, bar girl 18.9% and call girl 20.6%. In other groups, the so called 'low risk groups' are as follows; girl friends 10.4%, acquaintance 7.6% and wife 3.5%. In regard to prevalence of STD, nongonococcal urethritis and gonorrhea comprised 46.4% and 42.9%, respectively while chancroid, syphilis, herpes progenitalis and condyloma acuminatum were 2.2%, 0.9%, 0.9% and 1.0% respectively. CONCLUSION: We obtained the epidemiological data of the sexual partners of patients with STD. This will help us make STD prevention strategies.
Chancroid ; Contact Tracing ; Epidemiologic Studies ; Female ; Friends ; Gonorrhea ; Humans ; Male* ; Medical Records ; Prevalence ; Public Health ; Retrospective Studies ; Seoul ; Sex Workers ; Sexual Partners* ; Sexually Transmitted Diseases* ; Spouses ; Syphilis ; Urethritis

Sexually transmitted diseases (STDs) are the most common group of identifiable infectious diseases in many countries. Adolescents and young adults (15-24 years old) comprise only 25% of the sexually active population but represent almost 50% of all newly acquired STDs. In a law for prevention of infectious diseases in Korea, STDs include syphilis, gonorrhea, chancroid, nongonococcal urethritis, clamydial infection, genital herpes, and genital wart. Bacterial vaginosis, trichomoniasis, candidiasis, amebiasis, scabies, phthiriasis, granuloma inguinale, AIDS, and high risk human papilloma virus are also included in the STDs. Individuals infected with STDs are 5-10 times more likely than uninfected individuals to acquire or transmit HIV through sexual contacts. Their control is important considering the high incidences of acute infections, complications, and sequelae, their socioeconomic impact, and their role in increasing transmission of the HIV. The purpose of this paper is to summarize the treatment and management of STDs on the basis of Centers for Disease Control and Prevention treatment guidelines for sexually transmitted diseases published in 2006.
Adolescent ; Amebiasis ; Candidiasis ; Centers for Disease Control and Prevention (U.S.) ; Chancroid ; Communicable Diseases ; Condylomata Acuminata ; Gonorrhea ; Granuloma Inguinale ; Herpes Genitalis ; HIV ; Humans ; Incidence ; Jurisprudence ; Korea ; Papilloma ; Scabies ; Sexually Transmitted Diseases ; Syphilis ; Urethritis ; Vaginosis, Bacterial ; Viruses ; Young Adult

Screening and detecting sexually transmitted diseases (STDs) is a form of secondary prevention, which interrupts further transmission as well as progression of the infection and its sequelae. Unfortunately, primary prevention, by means of education and taking safe sex partners, has not been enough to significantly curb the prevalence and high cost of STDs. Bacterial STDs are decreasing in their prevalence whereas the prevalence of viral STDs has increased significantly in recent years. The differential diagnosis for genital ulcers, urethritis, and genital warts is very important. For example, syphilis, chancroid, lymphogranuloma venereum, and herpes simplex for genital ulcer are mistaken for other causes such as Behcet's syndrome, drug eruption, erythema multiforme, amebiasis, trauma, and carcinoma. Confirmatory testings made by cultures, PCR, or serologic studies are important for appropriate treatment and eradication of the disease in both patients and their partners. The physicians treating STDs should make special efforts to be sure that his or her methods of diagnosis and treatment reflect the latest knowledge, since the epidemiologic characteristics and treatment trends are rapidly changing based on newly appearing resistant strains.
Amebiasis ; Behcet Syndrome ; Chancroid ; Condylomata Acuminata ; Diagnosis, Differential ; Drug Eruptions ; Erythema Multiforme ; Genitalia ; Herpes Simplex ; Humans ; Lymphogranuloma Venereum ; Mass Screening ; Methylmethacrylates ; Polymerase Chain Reaction ; Polystyrenes ; Prevalence ; Primary Prevention ; Safe Sex ; Secondary Prevention ; Sexually Transmitted Diseases ; Syphilis ; Ulcer ; Urethritis

BACKGROUND: Almost all STD(sexually tranamitted diseases) have been increasing worldwide since the 1960s. In Korea, the occurrence of STD from recent trends of sexual openness and development in the pleasure-seeking industry is becoming a social issue. However, epidemiological studies and reports concerning the incidence of STD are lacking in Korea, especially in the sexually aetive young age group. OBJECTIVE: We evaluated the incidence of YTD and sexual behavior of recruits in a Korean arrny training center to contribute to the management of STD in Korea. METHODS: We studied 1304 recruits in a Korean army training center by questionnaire, physical examination and laboratory data. The subjects were divided into 3 groups: group 1(1072 persons), those who visited the hospital for evaluation of STD; group 2(641 persons), a control group for coitus rate; and group 3(1304 persons; group 1 plus 232 persons out of group 2), those who had coital experiences. RESULTS: 1. The incidence of STD in group 1 was 65.7%(704/1072) and that of the total number of recruits was 0.43%(704/164,134). 2. Among the 704 cases of STD, the most frequently observed STD was non-gonococcal urethritis, 292 cases(41.5%) and the second was gonorrhea, 236 cases(33.5%). The others were, 68 cases(9.7%) of pediculosis pubis, 41 cases(5.8%) of condyloma acuminatum, 29 cases(4.1%) of syphilis, 20 cases(2.8%) of combined STD, 14 cases(2%) of herpes progenitalis, 2 cases(0.28%) of molluscum cohtagiosum and 2 cases(0.28%) of chancroid. 3. The coitus rate in group 2 was 36.2%(232/641). 4. The incidence of previous STD in group 3 was 20.9%(273/1304). 5. The mn;t common form of STD which the patients experienced previously was urethritis(82.8%) and the others were pediculosis pubis(7.3%), syphilis(3.3%), condylcena acuminahun and herpes progenitalis. 6. The group with more sexual partners tended to have a lower educational level. 7. The experience rate of drug abuse was higher in the group with more sexual partners. 8. The experience rate of oral and anal sex was higher in the group with experiences of clrug abuse than in the ather one. CONCLUSION: In this study, urethritis was the most common form of STD(75% of all STD) and non-gonococcal urethritis showed a greater incidence than gonorrhea. The incidence of STD is thought to be closely related to the factors associated with social or behavioral science, such as the number of sexual partners, grade of education, drug abuse, experience of oral and anal sex. To accomplish more effective management of STD, therefore, the improvement of current social problems involving sexual openness, the pleasure-seeking industry and drug abuse should be achieved.
Behavioral Sciences ; Chancroid ; Coitus ; Education ; Epidemiologic Studies ; Gonorrhea ; Humans ; Incidence ; Korea ; Lice Infestations ; Physical Examination ; Sexual Behavior* ; Sexual Partners ; Sexually Transmitted Diseases* ; Social Problems ; Substance-Related Disorders ; Syphilis ; Urethritis ; Surveys and Questionnaires

The ‘32-year-old sailor’ patient was a native Korean male, infected with HIV through heterosexual contacts in the high risk areas of foreign country, mostly during. 1984 to 1986. During the following 6-months until his death, the skin nodules suggesting Kaposi's sarcoma, and penile ulcers like chancroid were gradually disappeared. Several skin diseases such as condyloma accuminatum, generalized xeiosis of the skin, acquired icthyosis, seborfheic dermatitis, diffuse hair loss and alopecia developed. His health gradually deteriorated with general symptom such as weakness, weight loss, remAtmt mild fever cough with sputum, and dyspnea with frequent pneumonia signs. The tongue became coated white and thick in which candida albicans was detected, and sore throat and dysphagia accompanied. The patients expired suddenly with acute respiratory distress syndrome, which was may be caused by a opportunistic infection of Pneumocystis carinii. In post-mortem autopsy studies, most of the lung tissue showed the findings of severe interstitial pneumonia and hyaline membrane formation, and pneumocystis cadnii and candida albicans were found in histopathological or micorbiological examination. As other infections, add fast bacilli suggesting Mycobacterium avium-intracellulare were found out in the lymph node, spleen, liver. Cytomegalovirus infection was found on the adrenal gland by histopathological examination. And various lymphoid tissue of the lymph node, spleen, thymus, respiratory tract, gastomtestinal tracts showed severe lymphoid depletion with fibrosis. The other findings had multiple glial nodules in the cerebral white matter and focal segmental glomerulosderosm There wasr t any evidence of Kaposi's sarcoma.
Adrenal Glands ; Alopecia ; Autopsy* ; Candida albicans ; Chancroid ; Cough ; Cytomegalovirus ; Cytomegalovirus Infections ; Deglutition Disorders ; Dermatitis ; Dyspnea ; Fever ; Fibrosis ; Hair ; Heterosexuality ; HIV ; Humans ; Hyalin ; Liver ; Lung ; Lung Diseases, Interstitial ; Lymph Nodes ; Lymphoid Tissue ; Male ; Membranes ; Mycobacterium avium Complex ; Opportunistic Infections ; Pharyngitis ; Pneumocystis ; Pneumocystis carinii ; Pneumonia ; Respiratory Distress Syndrome, Adult ; Respiratory System ; Sarcoma, Kaposi ; Skin ; Skin Diseases ; Spleen ; Sputum ; Thymus Gland ; Tongue ; Ulcer ; Weight Loss ; White Matter