No abstract available.
Chungcheongnam-do* ; Family Planning Services* ; Humans

bcl-2 and c-myc protein expression were studied in 44 epidermal (8 seborrheic keratoses, 21 squamous cell carcinomas, and 15 basal cell carcinomas), and 26 melanocytic tumors(8 nevi, and malignant melanomas) by immunohistochemistry using the specific anti-bcl-2 and anti-c-myc monoclonal antibodies. 14 out of 15 basal cell carcinomas(BCC) (93.3%) showed expression of bcl-2 protein, 12 of which (85.7%) showed coexpression of c-myc protein. In the melanocytic tumors, 7 out of 8 nevi showed bcl-2 expression (87.5%). Five of these 7 cases (62.5%) also showed c-myc protein expression. Eight of 18 malignant melanomas(MM) (44.4%) showed expression of bcl-2 protein and 7 of these 8 cases (38.9%) also showed c-myc protein expression. All seborrheic keratoses and squamous cell carcinoma(SCC) were negative for bcl-2 proteins. 12 of 15 SCCs(80%) were positive for c-myc protein. In conclusion, bcl-2 and c-myc proteins were coexpressed in BCCs, nevi, and MMs. Coexpression of bcl-2 and c-myc proteins in these tumors was statistically significant(p<0.01), while no considerable differences of bcl-2 and c-myc expression were found between nevi and MMs. These results suggests that bcl-2 may cooperate with c-myc to promote tumorigenesis of BCCs, nevi, and MMs(p<0.01).
Cell Transformation, Neoplastic

Gastric glomus tumor is an uncommon benign, submucosal neoplasm and does not require radical surgical procedure. Because there are no specific clinical or radiologic features associated with the glomus tumor, it can be recognized only by its histologic characteristics. We report a 30-year-old woman who had 10 years history of epigastric hunger pain. Radiologically, a gastric submucosal tumor was discovered, which was suggestive of leiomyoma. Gastric antrectomy was performed. The tumor cells showed immunohistochemical and ultrastructural evidence of smooth muscle differentiation.
Female ; Humans

We performed the intravitreal injection of air and pure perfluoropropane (C3F8) gas in the pigmented rabbits and observed the changes of gas levels by the ultrasonography. We also observed the changes of the intra-ocular gas levels by the ultrasonography and measured the intraocular pressures (lOPs) in 9 patients who had undergone vitrectomy and fluid-gas exchange with 20% sulfur hexafluoride (SF6) and 14% perfluoropropane (C3F8) gases. In the pigmented rabbits, the air was not expanded and completely absorbed within 2 days, and the C3F8 gas was expanded maximally at 3 to 7 days and completely absorbed after 3 weeks. Among nine human eyes treated with vitrectomy and fluid-gas exchange, the intraocular pressures were elevated above 25mmHg at 1 day after operation in 2 eyes, which were controlled with medical therapy. The lOPs were significantly correlated with the amount of the intraocular gases (r=0.3476, p<0.05). The assessment of intraocular gas level by ultrasonography seems to be easier and more objective method than others previously reported.
Absorption* ; Gases ; Humans ; Intraocular Pressure ; Intravitreal Injections ; Rabbits ; Sulfur Hexafluoride ; Ultrasonography ; Vitrectomy

We performed the intravitreal injection of air and pure perfluoropropane(C3F8) gas in the pigmented rabbits and observed the changes of gas levels by the ultrasonography. We also observed the changes of the intra-ocular gas levels by the ultrasonography and measured the intraocular pressures(IOPs) in 9 patients who had undergone vitrectomy and fluid-gas exchange with 20% sulfur hexafluoride(SF6) and 14% perfluoropropane(C3F8) gases. In the pigmented rabbits, the air was not expanded and completely absorbed within 2 days, and the C3F8 gas was expanded maximally at 3 to 7 days and completely absorbed after 3 weeks. Among nine human eyes treated with vitrectomy and fluid-gas exchange, the intraocular pressures were elevated above 25mmHg at 1 day after operation in 2 eyes, which were controlled with medical therapy. The lOPs were significantly correlated with the amount of the intraocular gases(r=0.3476, p<0.05). The assessment of intraocular gas level by ultrasonography seems to be easier and more objective method than others previously reported.
Absorption* ; Gases ; Humans ; Intraocular Pressure ; Intravitreal Injections ; Rabbits ; Sulfur ; Ultrasonography ; Vitrectomy

No abstract available.
Endometriosis* ; Female ; Omentum*

Merkel cell carcinoma (MCC) is an unusual primary cutaneous tumor, occasionally found con-current with other malignancies. A case of MCC with coexisting squamous cell carcinoma (SCC) was studied histologically, immunohistochemically and ultrastructurally. The MCC and SCC occured at the same site, but each preserved its identity and transition between the two was not identified.
Carcinoma, Merkel Cell* ; Carcinoma, Squamous Cell

No abstract available.
Hypoglycemia*

Pigmented fungiform papillae of the tongue is a rare disorder in Korea. It is characterized clinically by pigmentation confined to the fungiform papillae and histopathologically by the presence of melanophages in the upper dermis. We report a case of pigmented fungiform papillae of the tongue in a 21-year-old woman who had brown to violaceous dots on the fungiform papillae and pigmented patches on the right lateral dorsum of the tongue. Histological findings showed increased melanophages in the upper dermis.
Dermis ; Female ; Humans ; Korea ; Pigmentation ; Tongue* ; Young Adult

No abstract available.
Breast* ; Female* ; Humans